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Gene Regulation and Expression

  1. Ubiquitin-C-terminal hydrolases cleave isopeptide and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers

    Bett, J. S., Ritorto, M. S., Ewan, R., Jaffray, E. G., Virdee, S., Chin, J. W., Knebel, A., Kurz, T., Trost, M., Tatham, M. H. & Hay, R. T. 15 Mar 2015 In : Biochemical Journal. 466, 3, p. 489-498 10 p.

    Research output: Contribution to journalArticle

  2. Erratum: dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans

    Pelisch, F., Sonneville, R., Pourkarimi, E., Agostinho, A., Blow, J. J., Gartner, A. & Hay, R. T. 12 Feb 2015 In : Nature Communications. 6, 6352

    Research output: Contribution to journalArticle

  3. HIF-1α restricts NF-κB-dependent gene expression to control innate immunity signals

    Bandarra, D., Biddlestone, J., Mudie, S., Müller, H. -A. J. & Rocha, S. Feb 2015 In : Disease Models & Mechanisms. 8, 2, p. 169-181 13 p.

    Research output: Contribution to journalArticle

  4. Proteomic analysis of the response to cell cycle arrests in human myeloid leukemia cells

    Ly, T., Endo, A. & Lamond, A. I. 2 Jan 2015 In : eLife. 2015, 4, 15 p.e04534

    Research output: Contribution to journalArticle

  5. PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia

    Mudie, S., Bandarra, D., Batie, M., Biddlestone, J., Moniz, S., Ortmann, B., Shmakova, A. & Rocha, S. 15 Dec 2014 In : Cell Cycle. 13, 24, p. 3878-3891 14 p.

    Research output: Contribution to journalArticle

  6. Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans

    Pelisch, F., Sonneville, R., Pourkarimi, E., Agostinho, A., Blow, J. J., Gartner, A. & Hay, R. T. 5 Dec 2014 In : Nature Communications. 5, 12 p.5485

    Research output: Contribution to journalArticle

  7. Tetraspanin (TSP-17) Protects Dopaminergic Neurons against 6-OHDA-Induced Neurodegeneration in C. elegans

    Masoudi, N., Ibanez-Cruceyra, P., Offenburger, S-L., Holmes, A. & Gartner, A. 4 Dec 2014 In : PLoS Genetics. 10, 12, 15 p.e1004767

    Research output: Contribution to journalArticle

  8. FMDV replicons encoding green fluorescent protein are replication competent

    Tulloch, F., Pathania, U., Luke, G. A., Nicholson, J., Stonehouse, N. J., Rowlands, D. J., Jackson, T., Tuthill, T., Haas, J., Lamond, A. I. & Ryan, M. D. 1 Dec 2014 In : Journal of Virological Methods. 209, p. 35-40 6 p.

    Research output: Contribution to journalArticle

  9. Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner

    Bremm, A., Moniz, S., Mader, J., Rocha, S. & Komander, D. Dec 2014 In : EMBO Reports. 15, 12, p. 1268-1277 10 p.

    Research output: Contribution to journalArticle

  10. GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes

    Freeman, A. D. J., Liu, Y., Déclais, A-C., Gartner, A. & Lilley, D. M. J. Dec 2014 In : Journal of Molecular Biology. 426, 24, p. 3946-3959 14 p.

    Research output: Contribution to journalArticle

  11. Modelling multi-protein complexes using PELDOR distance measurements for rigid body minimisation experiments using XPLOR-NIH

    Hammond, C. M., Owen-Hughes, T. & Norman, D. G. Dec 2014 In : Methods (San Diego, Calif.). 70, 2-3, p. 139-153 15 p.

    Research output: Contribution to journalArticle

  12. Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control

    Bizarro, J., Charron, C., Boulon, S., Westman, B., Pradet-Balade, B., Vandermoere, F., Chagot, M-E., Hallais, M., Ahmad, Y., Leonhardt, H., Lamond, A., Manival, X., Branlant, C., Charpentier, B., Verheggen, C. & Bertrand, E. 24 Nov 2014 In : Journal of Cell Biology. 207, 4, p. 463-480 18 p.

    Research output: Contribution to journalArticle

  13. Having a direct look: analysis of DNA damage and repair mechanisms by next generation sequencing

    Meier, B. & Gartner, A. 15 Nov 2014 In : Experimental Cell Research. 329, 1, p. 35-41 7 p.

    Research output: Contribution to journalArticle

  14. Piezo1 integration of vascular architecture with physiological force

    Li, J. , Hou, B. , Tumova, S. , Muraki, K. , Bruns, A. , Ludlow, M. J. , Sedo, A. , Hyman, A. J. , McKeown, L. , Young, R. S. , Yuldasheva, N. Y. , Majeed, Y. , Wilson, L. A. , Rode, B. , Bailey, M. A. , Kim, H. R. , Fu, Z. , Carter, D. A. L. , Bilton, J. , Imrie, H. & 8 others Ajuh, P., Dear, T. N., Cubbon, R. M., Kearney, M. T., Prasad, K. R., Evans, P. C., Ainscough, J. F. X. & Beech, D. J. 13 Nov 2014 In : Nature. 515, 7526, p. 279-82 4 p.

    Research output: Contribution to journalArticle

  15. Dss1 is a 26S proteasome ubiquitin receptor

    Paraskevopoulos, K., Kriegenburg, F., Tatham, M. H., Rösner, H. I., Medina, B., Larsen, I. B., Brandstrup, R., Hardwick, K. G., Hay, R. T., Kragelund, B. B., Hartmann-Petersen, R. & Gordon, C. 6 Nov 2014 In : Molecular Cell. 56, 3, p. 453-461 9 p.

    Research output: Contribution to journalArticle

  16. Monitoring Keap1-Nrf2 interactions in single live cells

    Baird, L., Swift, S., Llères, D. & Dinkova-Kostova, A. T. 1 Nov 2014 In : Biotechnology Advances. 32, 6, p. 1133-1144 12 p.

    Research output: Contribution to journalArticle

  17. The spatial effect of protein deuteration on nitroxide spin-label relaxation: implications for EPR distance measurement

    El Mkami, H., Ward, R., Bowman, A., Owen-Hughes, T. & Norman, D. G. Nov 2014 In : Journal of Magnetic Resonance . 248, p. 36-41 6 p.

    Research output: Contribution to journalArticle

  18. Prohibitin is required for transcriptional repression by the WT1-BASP1 complex

    Toska, E., Shandilya, J., Goodfellow, S. J., Medler, K. F. & Roberts, S. G. E. 23 Oct 2014 In : Oncogene. 33, 43, p. 5100-5108 9 p.

    Research output: Contribution to journalArticle

  19. Stochasticity in the symmetric division of plant cells: when the exceptions are the rule

    Besson, S. & Dumais, J. 9 Oct 2014 In : Frontiers in Plant Science. 5, October, p. 538

    Research output: Contribution to journalArticle

  20. A 3D cellular context for the macromolecular world

    Patwardhan, A. , Ashton, A. , Brandt, R. , Butcher, S. , Carzaniga, R. , Chiu, W. , Collinson, L. , Doux, P. , Duke, E. , Ellisman, M. H. , Franken, E. , Grünewald, K. , Heriche, J-K. , Koster, A. , Kühlbrandt, W. , Lagerstedt, I. , Larabell, C. , Lawson, C. L. , Saibil, H. R. , Sanz-García, E. & 4 others Subramaniam, S., Verkade, P., Swedlow, J. R. & Kleywegt, G. J. Oct 2014 In : Nature Structural & Molecular Biology. 21, 10, p. 841-845 5 p.

    Research output: Contribution to journalComment/debate

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