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Gene Regulation and Expression

  1. The nucleoporin ALADIN regulates Aurora A localization to ensure robust mitotic spindle formation

    Carvalhal, S., Abreu Ribeiro, S., Arocena, M., Kasciukovic, T., Temme, A., Koehler, K., Huebner, A. & Griffis, E. R. 1 Oct 2015 In : Molecular Biology of the Cell. 26, 19, p. 3424-3438 15 p.

    Research output: Contribution to journalArticle

  2. Screen for multi-SUMO-binding proteins reveals a multi-SIM-binding mechanism for recruitment of the transcriptional regulator ZMYM2 to chromatin

    Aguilar-Martinez, E., Chen, X., Webber, A., Mould, A. P., Seifert, A., Hay, R. T. & Sharrocks, A. D. 1 Sep 2015 In : Proceedings of the National Academy of Sciences of the United States of America. 112, 35, p. E4854-E4863 10 p.

    Research output: Contribution to journalArticle

  3. Cezanne regulates E2F1-dependent HIF2α expression

    Moniz, S., Bandarra, D., Biddlestone, J., Campbell, K. J., Komander, D., Bremm, A. & Rocha, S. 15 Aug 2015 In : Journal of Cell Science. 128, 16, p. 3082-3093 12 p.

    Research output: Contribution to journalArticle

  4. Discovery of an unconventional centromere in budding yeast redefines evolution of point centromeres

    Kobayashi, N., Suzuki, Y., Schoenfeld, L., Müller, C., Nieduszynski, C., Wolfe, K. & Tanaka, T. 3 Aug 2015 In : Current Biology. 25, 15, p. 2026-2033 8 p.

    Research output: Contribution to journalArticle

  5. Structural basis for the RING catalyzed synthesis of K63 linked ubiquitin chains

    Branigan, E., Plechanovova, A., Jaffray, E. G., Naismith, J. H. & Hay, R. T. Aug 2015 In : Nature Structural & Molecular Biology. 22, 8, p. 597-602 6 p.

    Research output: Contribution to journalArticle

  6. Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C.elegans Embryos

    Sonneville, R., Craig, G., Labib, K., Gartner, A. & Blow, J. J. 21 Jul 2015 In : Cell Reports. 12, 3, p. 405-417 13 p.

    Research output: Contribution to journalArticle

  7. Proteotoxic stress reprograms the chromatin landscape of SUMO modification

    Seifert, A., Schofield, P., Barton, G. & Hay, R. 7 Jul 2015 In : Science Signaling. 8, 384, p. rs7 14 p.

    Research output: Contribution to journalArticle

  8. Global proteomics analysis of the response to starvation in C. elegans

    Larance, M., Pourkarimi, E., Wang, B., Brenes Murillo, A., Kent, R., Lamond, A. I. & Gartner, A. 1 Jul 2015 In : Molecular & Cellular Proteomics. 14, 7, p. 1989-2001 13 p.

    Research output: Contribution to journalArticle

  9. Maintenance of distinct melanocyte populations in the interfollicular epidermis

    Glover, J. D., Knolle, S., Wells, K. L., Liu, D., Jackson, I. J., Mort, R. L. & Headon, D. J. 1 Jul 2015 In : Pigment Cell and Melanoma Research. 28, 4, p. 476-480 5 p.

    Research output: Contribution to journalArticle

  10. Multidimentional proteomics for cell biology

    Larance, M. & Lamond, A. I. May 2015 In : Nature Reviews Molecular Cell Biology. 16, 5, p. 269-280 12 p.

    Research output: Contribution to journalArticle

  11. Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9

    Rojas-Fernandez, A., Herhaus, L., Macartney, T., Lachaud, C., Hay, R. T. & Sapkota, G. P. 29 Apr 2015 In : Scientific Reports. 5, 6 p., 9811

    Research output: Contribution to journalArticle

  12. HIF-1α, a novel piece in the NF-κB puzzle

    Bandarra, D. & Rocha, S. 28 Apr 2015 In : Infammation and Cell Signaling. 2, 1, 4 p., e792

    Research output: Contribution to journalArticle

  13. Dose-dependent effects of Allopurinol on human foreskin fibroblast cell and human umbilical vein endothelial cell under hypoxia

    Sun, Y., George, J. & Rocha, S. 1 Apr 2015 In : PLoS ONE. 10, 4, 12 p., e0123649

    Research output: Contribution to journalArticle

  14. The role of hypoxia in inflammatory disease (Review)

    Biddlestone, J., Bandarra, D. & Rocha, S. 1 Apr 2015 In : International Journal of Molecular Medicine. 35, 4, p. 859-869 11 p.

    Research output: Contribution to journalArticle

  15. Kinetochore-microtubule error correction is driven by differentially regulated interaction modes

    Kalantzaki, M., Kitamura, E., Zhang, T., Mino, A., Novák , B. & Tanaka, T. U. Apr 2015 In : Nature Cell Biology. 17, 4, p. 421-433 13 p.

    Research output: Contribution to journalArticle

  16. Ubiquitin-C-terminal hydrolases cleave isopeptide and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers

    Bett, J. S., Ritorto, M. S., Ewan, R., Jaffray, E. G., Virdee, S., Chin, J. W., Knebel, A., Kurz, T., Trost, M., Tatham, M. H. & Hay, R. T. 15 Mar 2015 In : Biochemical Journal. 466, 3, p. 489-498 10 p.

    Research output: Contribution to journalArticle

  17. Erratum: dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans

    Pelisch, F., Sonneville, R., Pourkarimi, E., Agostinho, A., Blow, J. J., Gartner, A. & Hay, R. T. 12 Feb 2015 In : Nature Communications. 6, 6352

    Research output: Contribution to journalArticle

  18. Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

    Shlien, A. , Campbell, B. B. , De Borja, R. , Alexandrov, L. B. , Merico, D. , Wedge, D. , Van Loo, P. , Tarpey, P. S. , Coupland, P. , Behjati, S. , Pollett, A. , Lipman, T. , Heidari, A. , Deshmukh, S. , Avitzur, N. , Meier, B. , Gerstung, M. , Hong, Y. , Merino, D. M. , Ramakrishna, M. & 42 others Remke, M., Arnold, R., Panigrahi, G. B., Thakkar, N. P., Hodel, K. P., Henninger, E. E., Göksenin, A. Y., Bakry, D., Charames, G. S., Druker, H., Lerner-Ellis, J., Mistry, M., Dvir, R., Grant, R., Elhasid, R., Farah, R., Taylor, G. P., Nathan, P. C., Alexander, S., Ben-Shachar, S., Ling, S. C., Gallinger, S., Constantini, S., Dirks, P., Huang, A., Scherer, S. W., Grundy, R. G., Durno, C., Aronson, M., Gartner, A., Meyn, M. S., Taylor, M. D., Pursell, Z. F., Pearson, C. E., Malkin, D., Futreal, P. A., Stratton, M. R., Bouffet, E., Hawkins, C., Campbell, P. J., Tabori, U. & for the Biallelic Mismatch Repair Deficiency Consortium 2 Feb 2015 In : Nature Genetics. 47, 3, p. 257-262 6 p.

    Research output: Contribution to journalLetter

  19. HIF-1α restricts NF-κB-dependent gene expression to control innate immunity signals

    Bandarra, D., Biddlestone, J., Mudie, S., Müller, H. -A. J. & Rocha, S. Feb 2015 In : Disease Models & Mechanisms. 8, 2, p. 169-181 13 p.

    Research output: Contribution to journalArticle

  20. Phosphorylation of Elp1 by Hrr25 is required for Elongator-dependent tRNA modification in yeast

    Abdel-Fattah, W., Jablonowski, D., Di Santo, R., Thüring, K. L., Scheidt, V., Hammermeister, A., ten Have, S., Helm, M., Schaffrath, R. & Stark, M. J. R. 8 Jan 2015 In : PLoS Genetics. 11, 1, 16 p., e1004931

    Research output: Contribution to journalArticle

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