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Gene Regulation and Expression

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  1. C. elegans whole genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency.

    Meier, B., Cooke, S. L., Weiss, J., Bailly, A. P., Alexandrov, L. B., Marshall, J., Raine, K., Maddison, M., Anderson, E., Stratton, M. R., Gartner, A. & Campbell, P. J. 16 Jul 2014 In : Genome Research.

    Research output: Contribution to journalArticle

  2. The contribution of dormant origins to genome stability: from cell biology to human genetics

    Alver, R. C., Chadha, G. S. & Blow, J. J. Jul 2014 In : DNA Repair. 19, p. 182-189 8 p.

    Research output: Contribution to journalArticle

  3. Structural insight into SUMO chain recognition and manipulation by the ubiquitin ligase RNF4

    Xu, Y., Plechanovová, A., Simpson, P., Marchant, J., Leidecker, O., Kraatz, S., Hay, R. T. & Matthews, S. J. 27 Jun 2014 In : Nature Communications. 5, 4217

    Research output: Contribution to journalArticle

  4. Proteomic Selection of Immunodiagnostic Antigens for Trypanosoma congolense

    Fleming, J. R., Sastry, L., Crozier, T. W. M., Napier, G. B., Sullivan, L. & Ferguson, M. A. J. 12 Jun 2014 In : PLoS Neglected Tropical Diseases. 8, 6, e2936

    Research output: Contribution to journalArticle

  5. A dynamic microtubule cytoskeleton directs medial actomyosin function during tube formation

    Booth, A. J. R., Blanchard, G. B., Adams, R. J. & Röper, K. 9 Jun 2014 In : Developmental Cell. 29, 5, p. 562-576 15 p.

    Research output: Contribution to journalArticle

  6. A conserved and essential basic region mediates tRNA binding to the Elp1 subunit of the Saccharomyces cerevisiae Elongator complex

    Di Santo, R., Bandau, S. & Stark, M. J. R. Jun 2014 In : Molecular Microbiology. 92, 6, p. 1227-1242 16 p.

    Research output: Contribution to journalArticle

  7. Sp100 isoform-specific regulation of human adenovirus 5 gene expression

    Berscheminski, J., Wimmer, P., Brun, J., Ip, W. H., Groitl, P., Horlacher, T., Jaffray, E., Hay, R. T., Dobner, T. & Schreiner, S. Jun 2014 In : Journal of Virology. 88, 11, p. 6076-6092 17 p.

    Research output: Contribution to journalArticle

  8. The essential roles of cytidine diphosphate-diacylglycerol synthase in bloodstream form Trypanosoma brucei

    Lilley, A. C., Major, L., Young, S., Stark, M. J. R. & Smith, T. K. May 2014 In : Molecular Microbiology. 92, 3, p. 453-470 18 p.

    Research output: Contribution to journalArticle

  9. Proteome-wide identification of SUMO2 modification sites

    Tammsalu, T., Matic, I., Jaffray, E. G., Ibrahim, A. F. M., Tatham, M. H. & Hay, R. T. 29 Apr 2014 In : Science Signaling. 7, 323, 10 p.rs2

    Research output: Contribution to journalArticle

  10. E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin

    Mackay, C., Carroll, E., Ibrahim, A. F. M., Garg, A., Inman, G. J., Hay, R. T. & Alpi, A. F. 15 Apr 2014 In : Cancer Research. 74, 8, p. 2246-2257 12 p.

    Research output: Contribution to journalArticle

  11. A perspective on proteomics in cell biology

    Ahmad, Y. & Lamond, A. I. Apr 2014 In : Trends in Cell Biology. 24, 4, p. 257-264 8 p.

    Research output: Contribution to journalScientific review

  12. NDK-1, the homolog of NM23-H1/H2 regulates cell migration and apoptotic engulfment in C. elegans

    Fancsalszky, L., Monostori, E., Farkas, Z., Pourkarimi, E., Masoudi, N., Hargitai, B., Bosnar, M. H., Deželjin, M., Zsákai, A., Vellai, T., Mehta, A. & Takács-Vellai, K. 21 Mar 2014 In : PLoS ONE. 9, 3, 12 p.e92687

    Research output: Contribution to journalArticle

  13. SUMO chain-induced dimerization activates RNF4

    Rojas-Fernandez, A., Plechanovová, A., Hattersley, N., Jaffray, E., Tatham, M. H. & Hay, R. T. 20 Mar 2014 In : Molecular Cell. 53, 6, p. 880-92 13 p.

    Research output: Contribution to journalArticle

  14. Near real-time processing of proteomics data using Hadoop.

    Hillman, C., Ahmad, Y., Whitehorn, M. & Cobley, A. 14 Mar 2014 In : Big Data. 2, 1, p. 44-49 5 p.

    Research output: Contribution to journalArticle

  15. Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae

    Makrantoni, V., Corbishley, S. J., Rachidi, N., Morrice, N. A., Robinson, D. A. & Stark, M. J. R. 18 Feb 2014 In : PLoS ONE. 9, 2, 15 p.e89399

    Research output: Contribution to journalArticle

  16. Time-resolved quantitative proteomics implicates the core snRNP protein SmB together with SMN in neural trafficking

    Prescott, A. R., Bales, A., James, J., Trinkle-Mulcahy, L. & Sleeman, J. E. 15 Feb 2014 In : Journal of Cell Science. 127, 4, p. 812-827 16 p.

    Research output: Contribution to journalArticle

  17. PML isoforms in response to arsenic: high-resolution analysis of PML body structure and degradation

    Hands, K. J., Cuchet-Lourenco, D., Everett, R. D. & Hay, R. T. 15 Jan 2014 In : Journal of Cell Science. 127, 2, p. 365-375 11 p.

    Research output: Contribution to journalArticle

  18. Grow₂: The HIF system, energy homeostasis and the cell cycle

    Moniz, S., Biddlestone, J. & Rocha, S. 10 Jan 2014 In : Histology and Histopathology.

    Research output: Contribution to journalArticle

  19. Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1

    Poh, W. T., Chadha, G. S., Gillespie, P. J., Kaldis, P. & Blow, J. J. Jan 2014 In : Open Biology. 4, 130138

    Research output: Contribution to journalArticle

  20. Phosphorylated DegU manipulates cell fate differentiation in the Bacillus subtilis biofilm

    Marlow, V. L., Porter, M., Hobley, L., Kiley, T. B., Swedlow, J. R., Davidson, F. A. & Stanley-Wall, N. R. Jan 2014 In : Journal of Bacteriology. 196, 1, p. 16-27 10 p.

    Research output: Contribution to journalArticle

  21. The prevalence and origin of exoprotease producing cells in the Bacillus subtilis biofilm

    Marlow, V. L., Cianfanelli, F. R., Porter, M., Cairns, L. S., Dale, J. K. & Stanley-Wall, N. R. Jan 2014 In : Microbiology-SGM. 160, 1, p. 56-66 11 p.

    Research output: Contribution to journalArticle

  22. Analysis of Global RNA Synthesis at the Single Cell Level following Hypoxia

    Biddlestone, J., Druker, J., Shmakova, A., Ferguson, G., Swedlow, J. R. & Rocha, S. 2014 In : JoVE: Journal of Visualized Experiments. 87

    Research output: Contribution to journalArticle

  23. Biochemical analysis of TssK, a core component of the bacterial Type VI secretion system, reveals distinct oligomeric states of TssK and identifies a TssK-TssFG sub-complex

    English, G., Byron, O., Cianfanelli, F. R., Prescott, A. R. & Coulthurst, S. J. 2014 In : Biochemical Journal. 461, 2, p. 291-304 14 p.

    Research output: Contribution to journalArticle

  24. Cell cycle progression in response to oxygen levels

    Ortmann, B., Rocha, S. & Druker, J. 2014 In : Cellular and Molecular Life Sciences. 14 p.

    Research output: Contribution to journalArticle

  25. siRNA screening to identify ubiquitin and ubiquitin-like system regulators of biological pathways in cultured mammalian cells

    Bett, J. S., Ibrahim, A. F. M., Garg, A. K., Rocha, S. & Hay, R. T. 2014 In : JoVE: Journal of Visualized Experiments. 87, e51572

    Research output: Contribution to journalArticle

  26. The double loop mattress suture

    Biddlestone, J., Samuel, M., Creagh, T. & Ahmad, T. 2014 In : Wound Repair and Regeneration. 22, 3, p. 415-423 9 p.

    Research output: Contribution to journalArticle

  27. The histone chaperones Vps75 and Nap1 form ring-like, tetrameric structures in solution

    Bowman, A., Hammond, C. M., Stirling, A., Ward, R., Shang, W., El-Mkami, H., Robinson, D. A., Svergun, D. I., Norman, D. G., Owen-Hughes, T. & Singh, V. 2014 In : Nucleic Acids Research. 42, 9, p. 6038-6051 13 p.

    Research output: Contribution to journalArticle

  28. Characterization of Native Protein Complexes and Protein Isoform Variation Using Size-fractionation-based Quantitative Proteomics

    Kirkwood, K. J., Ahmad, Y., Larance, M. & Lamond, A. I. 1 Dec 2013 In : Molecular & Cellular Proteomics. 12, 12, p. 3851-3873 23 p.

    Research output: Contribution to journalArticle

  29. Three wise centromere functions: see no error, hear no break, speak no delay

    Tanaka, T. U., Clayton, L. & Natsume, T. Dec 2013 In : EMBO Reports. 14, 12, p. 1073-1083 11 p.

    Research output: Contribution to journalScientific review

  30. Stress Response: Anything that Doesn't Kill You Makes You Stronger

    Gartner, A. & Akay, A. 18 Nov 2013 In : Current Biology. 23, 22, p. R1012-R1014 3 p.

    Research output: Contribution to journalArticle

  31. A comparison of in vitro nucleosome positioning mapped with chicken, frog and a variety of yeast core histones

    Allan, J., Fraser, R. M., Owen-Hughes, T., Docherty, K. & Singh, V. 15 Nov 2013 In : Journal of Molecular Biology. 425, 22, p. 4206-4222 17 p.

    Research output: Contribution to journalArticle

  32. Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

    Brown, S. J. , Madhok, V. B. & 32 others Saunders, S. P., Goh, C. S. M., Palmer, C. N. A., Porter, R. M., Cole, C., Campbell, L. E., Gierlinski, M., Barton, G. J., Schneider, G., Balmain, A., Prescott, A. R., Weidinger, S., Baurecht, H., Kabesch, M., Gieger, C., Lee, Y-A., Tavendale, R., Mukhopadhyay, S., Turner, S. W., Sullivan, F. M., Relton, C., Burn, J., Meggitt, S., Smith, C. H., Allen, M. A., Barker, J. N. W. N., Reynolds, N. J., Cordell, H. J., Irvine, A. D., McLean, W. H. I., Sandilands, A. & Fallon, P. G. Nov 2013 In : Journal of Allergy and Clinical Immunology. 132, 5, p. 1121-1129 9 p.

    Research output: Contribution to journalArticle

  33. RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans

    Akay, A., Craig, A., Lehrbach, N., Larance, M., Pourkarimi, E., Wright, J. E., Lamond, A., Miska, E. & Gartner, A. Nov 2013 In : Open Biology. 3, 130151

    Research output: Contribution to journalArticle

  34. The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing

    Caillat, C., Pefani, D-E., Gillespie, P. J., Taraviras, S., Blow, J. J., Lygerou, Z. & Perrakis, A. Nov 2013 In : Journal of Biological Chemistry. 288, 44, p. 31624-31634 11 p.

    Research output: Contribution to journalArticle

  35. Structural biology: Pivotal findings for a transcription machine

    Zomerdijk, J. 31 Oct 2013 In : Nature. 502, 7473, p. 629-630 2 p.

    Research output: Contribution to journalArticle

  36. Bod1 regulates protein phosphatase 2A at mitotic kinetochores

    Porter, I., Schleicher, K., Porter, M. & Swedlow, J. 25 Oct 2013 In : Nature Communications. 4, 2677

    Research output: Contribution to journalArticle

  37. HIF-independent role of prolyl hydroxylases in the cellular response to amino acids

    Durán, R. V., Mackenzie, E. D., Boulahbel, H., Frezza, C., Heiserich, L., Tardito, S., Bussolati, O., Rocha, S., Hall, M. N. & Gottlieb, E. 19 Sep 2013 In : Oncogene. 32, 38, p. 4549-4556 8 p.

    Research output: Contribution to journalArticle

  38. PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192

    Moser, S. C., Bensaddek, D., Ortmann, B., Maure, J-F., Mudie, S., Blow, J. J., Lamond, A. I., Swedlow, J. R. & Rocha, S. 26 Aug 2013 In : Developmental Cell. 26, 4, p. 381-392 12 p.

    Research output: Contribution to journalArticle

  39. Plant SILAC: stable-isotope labelling with amino acids of Arabidopsis seedlings for quantitative proteomics

    Lewandowska, D., ten Have, S., Hodge, K., Tillemans, V., Lamond, A. I. & Brown, J. W. S. 20 Aug 2013 In : PLoS ONE. 8, 8, e72207

    Research output: Contribution to journalArticle

  40. Locus-specific proteomics by TChP: targeted chromatin purification

    Pourfarzad, F., Aghajanirefah, A., de Boer, E., Ten Have, S., Bryn van Dijk, T., Kheradmandkia, S., Stadhouders, R., Thongjuea, S., Soler, E., Gillemans, N., von Lindern, M., Demmers, J., Philipsen, S. & Grosveld, F. 15 Aug 2013 In : Cell Reports. 4, 3, p. 589-600 12 p.

    Research output: Contribution to journalArticle

  41. The NM23-H1/H2 homolog NDK-1 is required for full activation of Ras signaling in C. elegans

    Masoudi, N., Fancsalszky, L., Pourkarimi, E., Vellai, T., Alexa, A., Reményi, A., Gartner, A., Mehta, A. & Takács-Vellai, K. 15 Aug 2013 In : Development. 140, 16, p. 3486-3495 10 p.

    Research output: Contribution to journalArticle

  42. BslA is a self-assembling bacterial hydrophobin that coats the Bacillus subtilis biofilm

    Hobley, L., Ostrowski, A., Rao, F. V., Bromley, K. M., Porter, M., Prescott, A. R., Macphee, C. E., van Aalten, D. M. F. & Stanley-Wall, N. R. 13 Aug 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 33, p. 13600-13605 6 p.

    Research output: Contribution to journalArticle

  43. Cleaning up the masses: Exclusion lists to reduce contamination with HPLC-MS/MS

    Hodge, K., Ten Have, S., Hutton, L. & Lamond, A. I. 2 Aug 2013 In : Journal of Proteomics. 88, p. 92-103 12 p.

    Research output: Contribution to journalArticle

  44. Clinical proteomics stretch goals: EuPA 2012 roundtable report

    O'Neil, S. E., Palviainen, M. J., Ten Have, S., Filiou, M., Gonzalez, A., Hodge, K., Surinova, S., Penque, D. & Baker, M. S. 2 Aug 2013 In : Journal of Proteomics. 88, p. 37-40 4 p.

    Research output: Contribution to journalArticle

  45. PROTEINCHALLENGE: Crowd sourcing in proteomics analysis and software development

    Martin, S. F., Falkenberg, H., Dyrlund, T. F., Khoudoli, G. A., Mageean, C. J. & Linding, R. 2 Aug 2013 In : Journal of Proteomics. 88, p. 41-46 6 p.

    Research output: Contribution to journalArticle

  46. FMN2 is a novel regulator of the cyclin-dependent kinase inhibitor p21

    Yamada, K., Ono, M., Bensaddek, D., Lamond, A. I. & Rocha, S. 1 Aug 2013 In : Cell cycle (Georgetown, Tex.). 12, 15, p. 2348-2354 7 p.

    Research output: Contribution to journalArticle

  47. Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases

    Agostinho, A., Meier, B., Sonneville, R., Jagut, M., Woglar, A., Blow, J., Jantsch, V. & Gartner, A. 18 Jul 2013 In : PLoS Genetics. 9, 7, e1003591

    Research output: Contribution to journalArticle

  48. Kinetochores coordinate pericentromeric cohesion and early DNA replication by Cdc7-Dbf4 kinase recruitment

    Natsume, T., Müller, C. A., Katou, Y., Retkute, R., Gierlinski, M., Araki, H., Blow, J. J., Shirahige, K., Nieduszynski, C. A. & Tanaka, T. U. 6 Jun 2013 In : Molecular Cell. 50, 5, p. 661-674 14 p.

    Research output: Contribution to journalArticle

  49. Insights into Diphthamide, key Diphtheria Toxin effector

    Abdel-Fattah, W., Scheidt, V., Uthman, S., Stark, M. J. R. & Schaffrath, R. 3 May 2013 In : Toxins. 5, 5, p. 958-968 11 p.

    Research output: Contribution to journalArticle

  50. Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease

    Sharifi, R. , Morra, R. , Appel, C. D. , Tallis, M. , Chioza, B. , Jankevicius, G. , Simpson, M. A. , Matic, I. , Ozkan, E. , Golia, B. , Schellenberg, M. J. , Weston, R. , Williams, J. G. , Rossi, M. N. , Galehdari, H. , Krahn, J. , Wan, A. , Trembath, R. C. , Crosby, A. H. , Ahel, D. & 5 others Hay, R., Ladurner, A. G., Timinszky, G., Williams, R. S. & Ahel, I. 2 May 2013 In : EMBO Journal. 32, 9, p. 1225-1237 13 p.

    Research output: Contribution to journalArticle

  51. miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity

    Remenyi, J., van den Bosch, M. W. M., Palygin, O., Mistry, R. B., McKenzie, C., Macdonald, A., Hutvagner, G., Arthur, J. S. C., Frenguelli, B. G. & Pankratov, Y. 26 Apr 2013 In : PLoS ONE. 8, 4, 14 p.e62509

    Research output: Contribution to journalArticle

  52. Analysis of human protein replacement stable cell lines established using snoMEN-PR vector

    Ono, M., Yamada, K., Endo, A., Avolio, F. & Lamond, A. I. 25 Apr 2013 In : PLoS ONE. 8, 4, 12 p.e62305

    Research output: Contribution to journalArticle

  53. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability

    Bett, J. S., Ibrahim, A. F. M., Garg, A. K., Kelly, V., Pedrioli, P., Rocha, S. & Hay, R. T. 15 Apr 2013 In : Biochemical Journal. 451, 2, p. 185-194 10 p.BJ20130026

    Research output: Contribution to journalArticle

  54. Correlative imaging of fluorescent proteins in resin-embedded plant material

    Bell, K., Mitchell, S., Paultre, D., Posch, M. & Oparka, K. Apr 2013 In : Plant Physiology. 161, 4, p. 1595-1603 9 p.

    Research output: Contribution to journalArticle

  55. Decoding the SUMO signal

    Hay, R. T. Apr 2013 In : Biochemical Society Transactions. 41, 2, p. 463-473 11 p.

    Research output: Contribution to journalArticle

  56. Degradation characteristics of the major PML isoforms in response to arsenic

    Hands, K. J., Cuchet-Lourenco, D., Everett, R. D. & Hay, R. T. Apr 2013 In : British Journal of Haematology. 161, Suppl. 1, p. 17 1 p.35

    Research output: Contribution to journalMeeting abstract

  57. Small RNAs derived from the 5' end of tRNA can inhibit protein translation in human cells

    Sobala, A. & Hutvagner, G. Apr 2013 In : RNA Biology. 10, 4, p. 553-563 11 p.

    Research output: Contribution to journalArticle

  58. Topoisomerase IIα promotes activation of RNA polymerase i transcription by facilitating pre-initiation complex formation

    Ray, S., Panova, T., Miller, G., Volkov, A., Porter, A. C. G., Russell, J., Panov, K. I. & Zomerdijk, J. C. B. M. 19 Mar 2013 In : Nature Communications. 4, 1598

    Research output: Contribution to journalArticle

  59. Global subcellular characterization of protein degradation using quantitative proteomics

    Larance, M., Ahmad, Y., Kirkwood, K. J., Ly, T. & Lamond, A. I. Mar 2013 In : Molecular & Cellular Proteomics. 12, 3, p. 638-650 13 p.

    Research output: Contribution to journalArticle

  60. Identification and functional characterization of FMN2: a regulator of the cyclin-dependent kinase Inhibitor p21

    Yamada, K., Ono, M., Perkins, N. D., Rocha, S. & Lamond, A. I. Mar 2013 In : Molecular Cell. 49, 5, p. 922-933 12 p.

    Research output: Contribution to journalArticle

  61. DNA-binding regulates site-specific ubiquitination of IRF-1

    Landré, V., Pion, E., Narayan, V., Xirodimas, D. P. & Ball, K. L. 1 Feb 2013 In : Biochemical Journal. 449, 3, p. 707-717 11 p.

    Research output: Contribution to journalArticle

  62. Web-based visualisation and analysis of 3D electron-microscopy data from EMDB and PDB

    Lagerstedt, I., Moore, W. J., Patwardhan, A., Sanz-García, E., Best, C., Swedlow, J. R. & Kleywegt, G. J. 1 Jan 2013 In : Journal of Structural Biology. 184, 2, p. 173-181 9 p.

    Research output: Contribution to journalArticle

  63. A role for paralog-specific sumoylation in histone deacetylase 1 stability

    Citro, S., Jaffray, E., Hay, R. T., Seiser, C. & Chiocca, S. 2013 In : Journal of Molecular Cell Biology. 5, 6, p. 416-427 12 p.

    Research output: Contribution to journalArticle

  64. A sweet TET-a-tete-synergy of TET proteins and O-GlcNAc transferase in transcription

    Mariappa, D., Pathak, S. & van Aalten, D. M. F. 2013 In : EMBO Journal. 32, 5, p. 612-613 2 p.

    Research output: Contribution to journalEditorial

  65. CENP-A confers a reduction in height on octameric nucleosomes

    Miell, M. D. D., Barysz, H. M., Rappsilber, J., Allshire, R. C., Fuller, C. J., Straight, A. F., Guse, A., Downes, A. & Owen-Hughes, T. 2013 In : Nature Structural & Molecular Biology.

    Research output: Contribution to journalArticle

  66. Degradation characteristics of the major PML isoforms in response to arsenic

    Hands, K. J., Cuchet-Lourenco, D., Everett, R. D. & Hay, R. T. 2013

    Research output: Contribution to conferenceAbstract

  67. Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant

    Earnshaw, W. C. , Allshire, R. C. , Black, B. E. , Bloom, K. , Salmon, E. D. , Brinkley, B. R. , Brown, W. , Cheeseman, I. M. , Choo, K. H. A. , Copenhaver, G. P. , DeLuca, J. G. , Luger, K. , Desai, A. , Oegema, K. , Cleveland, D. W. , Diekmann, S. , Erhardt, S. , Fitzgerald-Hayes, M. , Foltz, D. , Fukagawa, T. & 37 others Gassmann, R., Maiato, H., Gerlich, D. W., Glover, D. M., Gorbsky, G. J., Harrison, S. C., Heun, P., Hirota, T., Jansen, L. E. T., Karpen, G., Kops, G. J. P. L., Lampson, M. A., Lens, S. M., Losada, A., Maddox, P. S., Margolis, R. L., Masumoto, H., McAinsh, A. D., Mellone, B. G., O'Neill, R. J., Meraldi, P., Musacchio, A., Scott, K. C., Sullivan, B. A., Straight, A. F., Stukenberg, P. T., Sullivan, K. F., Sunkel, C. E., Swedlow, J. R., Walczak, C. E., Warburton, P. E., Westermann, S., Willard, H. F., Wordeman, L., Yanagida, M., Yen, T. J. & Yoda, K. 2013 In : Chromosome Research. 21, 2, p. 101-106 6 p.

    Research output: Contribution to journalArticle

  68. Germ cell apoptosis and DNA damage responses

    Bailly, A. & Gartner, A. 2013 Germ Cell Development in C. elegans. Schedl, T. (ed.). New York: Springer, Vol. 757, p. 249-276 28 p. (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  69. Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes

    Narlikar, G. J., Sundaramoorthy, R. & Owen-Hughes, T. 2013 In : Cell. 154, 3, p. 490-503 14 p.

    Research output: Contribution to journalArticle

  70. Modification of Akt by SUMO conjugation regulates alternative splicing and cell cycle

    Risso, G., Pelisch, F., Pozzi, B., Mammi, P., Blaustein, M., Colman-Lerner, A. & Srebrow, A. 2013 In : Cell Cycle. 12, 19, p. 3165-3174 10 p.

    Research output: Contribution to journalArticle

  71. Modulation of higher order chromatin conformation in mammalian cell nuclei can be mediated by polyamines and divalent cations

    Visvanathan, A., Ahmed, K., Even-Faitelson, L., Lleres, D., Bazett-Jones, D. P. & Lamond, A. I. 2013 In : PLoS ONE. 8, 6, 16 p. e67689

    Research output: Contribution to journalArticle

  72. Replisome stall events have shaped the distribution of replication origins in the genomes of yeasts

    Newman, T. J., Mamun, M. A., Nieduszynski, C. A. & Blow, J. J. 2013 In : Nucleic Acids Research. n/a, 14 p.n/a

    Research output: Contribution to journalArticle

  73. Stochastic association of neighboring replicons creates replication factories in budding yeast

    Saner, N., Karschau, J., Natsume, T., Gierlinski, M., Retkute, R., Hawkins, M., Nieduszynski, C. A., Blow, J. J., de Moura, A. P. S. & Tanaka, T. U. 2013 In : Journal of Cell Biology. 202, 7, p. 1001-1012 12 p.

    Research output: Contribution to journalArticle

  74. Structural biology: Pivotal findings for a transcription machine

    Zomerdijk, J. 2013 In : Nature. 502, 7473, p. 629-630 2 p.

    Research output: Contribution to journalArticle

  75. TfR1 interacts with the IKK complex and is involved in IKK-NF-kappaB signalling

    Kenneth, N. S., Mudie, S., Naron, S. & Rocha, S. 2013 In : Biochemical Journal. 449, p. 275-284

    Research output: Contribution to journalArticle

  76. The amidation step of Diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction network

    Uthman, S., Baer, C., Scheidt, V., Liu, S., Ten Have, S., Giorgini, F., Stark, M. J. R. & Schaffrath, R. 2013 In : PLoS Genetics. 9, 2, e1003334

    Research output: Contribution to journalArticle

  77. Ube2W conjugates ubiquitin to α-amino groups of protein N-termini

    Tatham, M. H., Plechanovova, A., Jaffray, E. G., Salmen, H. & Hay, R. T. 2013 In : Biochemical Journal. 453, 1, p. 137-145 9 p.

    Research output: Contribution to journalArticle

  78. Ubiquitylation-dependent localization of PLK1 in mitosis

    Beck, J., Maerki, S., Posch, M., Metzger, T., Persaud, A., Scheel, H., Hofmann, K., Rotin, D., Pedrioli, P., Swedlow, J. R., Peter, M. & Sumara, I. 2013 In : Nature Cell Biology. 15, 4, p. 430-439 10 p.

    Research output: Contribution to journalArticle

  79. Heterologous SUMO-2/3-Ubiquitin Chains Optimize IκBα Degradation and NF-κB Activity

    Aillet, F., Lopitz-Otsoa, F., Egaña, I., Hjerpe, R., Fraser, P., Hay, R. T., Rodriguez, M. S. & Lang, V. 20 Dec 2012 In : PLoS ONE. 7, 12, e51672

    Research output: Contribution to journalArticle

  80. Structural plasticity of histones H3–H4 facilitates their allosteric exchange between RbAp48 and ASF1

    Zhang, W., Yyl, M., Ward, R., Sobott, F., Maman, J., Murthy, A., Watson, A., Fedorov, O., Bowman, A., Owen-Hughes, T., El Mkami, H., Murzina, N., Norman, D. G. & Laue, E. 25 Nov 2012 In : Nature Structural & Molecular Biology. 20, 1, p. 29-35

    Research output: Contribution to journalArticle

  81. Dormant Origins, the Licensing Checkpoint, and the Response to Replicative Stresses

    McIntosh, D. & Blow, J. J. Oct 2012 In : Cold spring harbor perspectives in biology. 4, 10, 10 p.012955

    Research output: Contribution to journalArticle

  82. Family with Sequence Similarity 60A (FAM60A) Protein Is a Cell Cycle-fluctuating Regulator of the SIN3-HDAC1 Histone Deacetylase Complex

    Munoz, I. M., Macartney, T., Sanchez-Pulido, L., Ponting, C. P., Rocha, S. & Rouse, J. 21 Sep 2012 In : Journal of Biological Chemistry. 287, 39, p. 32346-53 8 p.

    Research output: Contribution to journalArticle

  83. The control of cell energy metabolism by NF-j B transcription factors

    Mauro, C., Leow, S. C., Anso, E., Rocha, S., Thotakura, A. K., Tornatore, L., Moretti, M., De Smaele, E., Beg, A. A., Tergaonkar, V., Chandel, N. S. & Franzoso, G. Sep 2012 In : Immunology. 137, S1, p. 19 1 p.

    Research output: Contribution to journalMeeting abstract

  84. Exploiting the MDM2-CK1α protein-protein interface to develop novel biologics that induce UBL-kinase-modification and inhibit cell growth

    Huart, A-S., MacLaine, N. J., Narayan, V. & Hupp, T. R. 20 Aug 2012 In : PLoS ONE. 7, 8, e43391

    Research output: Contribution to journalArticle

  85. Reanalysis of phosphoproteomics data uncovers ADP-ribosylation sites

    Matic, I., Ahel, I. & Hay, R. T. Aug 2012 In : Nature Methods. 9, 8, p. 771-772 2 p.

    Research output: Contribution to journalLetter

  86. ALDH2 mediates 5-nitrofuran activity in multiple species

    Zhou, L., Ishizaki, H., Spitzer, M., Taylor, K. L., Temperley, N. D., Johnson, S. L., Brear, P., Gautier, P., Zeng, Z., Mitchell, A., Narayan, V., McNeil, E. M., Melton, D. W., Smith, T. K., Tyers, M., Westwood, N. J. & Patton, E. E. 27 Jul 2012 In : Chemistry & Biology. 19, 7, p. 883-892 10 p.

    Research output: Contribution to journalArticle

  87. Influence of the nuclear membrane, active transport, and cell shape on the Hes1 and p53-Mdm2 pathways: insights from spatio-temporal modelling

    Sturrock, M., Terry, A. J., Xirodimas, D. P., Thompson, A. M. & Chaplain, M. A. J. Jul 2012 In : Bulletin of Mathematical Biology. 74, 7, p. 1531-1579 49 p.

    Research output: Contribution to journalArticle

  88. SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage

    Yin, Y., Seifert, A., Chua, J. S., Maure, J-F., Golebiowski, F. & Hay, R. T. 1 Jun 2012 In : Genes & Development. 26, 11, p. 1196-1208 13 p.

    Research output: Contribution to journalArticle

  89. Preparation and use of Xenopus egg extracts to study DNA replication and chromatin associated proteins

    Gillespie, P. J., Gambus, A. & Blow, J. J. Jun 2012 In : Methods. 57, 2, p. 203-13 11 p.

    Research output: Contribution to journalArticle

  90. Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation

    Klotz-Noack, K., McIntosh, D., Schurch, N., Pratt, N. & Blow, J. J. 15 May 2012 In : Journal of Cell Science. 125, 10, p. 2436-2445 10 p.

    Research output: Contribution to journalArticle

  91. A quantitative proteomic analysis of lung epithelial (A549) cells infected with 2009 pandemic influenza A virus using stable isotope labelling with amino acids in cell culture

    Dove, B. K., Surtees, R., Bean, T. J. H., Munday, D., Wise, H. M., Digard, P., Carroll, M. W., Ajuh, P., Barr, J. N. & Hiscox, J. A. May 2012 In : Proteomics. 12, 9, p. 1431-1436 6 p.

    Research output: Contribution to journalArticle

  92. The p53 isoforms are differentially modified by Mdm2

    Camus, S., Menendez, S., Fernandes, K., Kua, N., Liu, G., Xirodimas, D. P., Lane, D. P. & Bourdon, J-C. 15 Apr 2012 In : Cell Cycle. 11, 8, p. 1646-1655 10 p.

    Research output: Contribution to journalArticle

  93. Human box C/D snoRNA processing conservation across multiple cell types

    Scott, M. S., Ono, M., Yamada, K., Endo, A., Barton, G. J. & Lamond, A. I. Apr 2012 In : Nucleic Acids Research. 40, 8, p. 3676-3688 13 p.

    Research output: Contribution to journalArticle

  94. Micrococcal Nuclease Does Not Substantially Bias Nucleosome Mapping

    Allan, J., Fraser, R. M., Owen-Hughes, T. & Keszenman-Pereyra, D. 30 Mar 2012 In : Journal of Molecular Biology. 417, 3, p. 152-164 13 p.

    Research output: Contribution to journalArticle

  95. Diphtheria disease and genes involved in formation of diphthamide, key effector of the diphtheria toxin

    Uthman, S., Liu, S., Giorgini, F., Stark, M. J. R., Costanzo, M. & Schaffrath, R. 21 Mar 2012 Insight and Control of Infectious Disease in Global Scenario . Roy, P. K. (ed.). Croatia: In Tech - Open Access Publisher, p. 333-357 25 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  96. The ubiquitin E1 enzyme Ube1 mediates NEDD8 activation under diverse stress conditions

    Leidecker, O., Matic, I., Mahata, B., Pion, E. & Xirodimas, D. P. 15 Mar 2012 In : Cell Cycle. 11, 6, p. 1142-1150 9 p.

    Research output: Contribution to journalArticle

  97. Polypyrimidine Tract Binding Protein (hnRNP I) Is Possibly a Conserved Modulator of miRNA-Mediated Gene Regulation

    Engels, B., Jannot, G., Remenyi, J., Simard, M. J. & Hutvagner, G. 9 Mar 2012 In : PLoS ONE. 7, 3, p. - 11 p.e33144

    Research output: Contribution to journalArticle

  98. A quantitative spatial proteomics analysis of proteome turnover in human cells

    Boisvert, F-M., Ahmad, Y., Gierlinski, M., Charrière, F., Lamont, D., Scott, M., Barton, G. & Lamond, A. I. 1 Mar 2012 In : Molecular & Cellular Proteomics. 11, 3, M111.011429

    Research output: Contribution to journalArticle

  99. Advancing cell biology through proteomics in space and time (PROSPECTS)

    Lamond, A. I., Uhlen, M., Horning, S., Makarov, A., Robinson, C. V., Serrano, L., Hartl, F. U., Baumeister, W., Werenskiold, A. K., Andersen, J. S., Vorm, O., Linial, M., Aebersold, R. & Mann, M. 1 Mar 2012 In : Molecular & Cellular Proteomics. 11, 3

    Research output: Contribution to journalArticle

  100. Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway

    Larance, M., Kirkwood, K. J., Xirodimas, D. P., Lundberg, E., Uhlen, M. & Lamond, A. I. 1 Mar 2012 In : Molecular & Cellular Proteomics. 11, 3

    Research output: Contribution to journalArticle

  101. OMERO: flexible, model-driven data management for experimental biology

    Allan, C. , Burel, J-M. , Moore, J. , Blackburn, C. , Linkert, M. , Loynton, S. , MacDonald, D. , Moore, W. J. , Neves, C. , Patterson, A. , Porter, M. , Tarkowska, A. , Loranger, B. , Avondo, J. , Lagerstedt, I. , Lianas, L. , Leo, S. , Hands, K. , Hay, R. T. , Patwardhan, A. & 4 others Best, C., Kleywegt, G. J., Zanetti, G. & Swedlow, J. R. 1 Mar 2012 In : Nature Methods. 9, 3, p. 245-253 9 p.

    Research output: Contribution to journalArticle

  102. Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization

    Ahmad, Y., Boisvert, F-M., Lundberg, E., Uhlen, M. & Lamond, A. I. 1 Mar 2012 In : Molecular & Cellular Proteomics. 11, 3

    Research output: Contribution to journalArticle

  103. Tratamiento exitoso de la necrosis isquémica del glande poscircuncisión con oxígeno hiperbárico y pentoxifilina intravenosa

    Elemen, L., Akay, A., Topçu, K. & Gürcan, N. I. 1 Mar 2012 In : Actas Urologicas Espanolas. 36, 3, p. 200-201 2 p.

    Research output: Contribution to journalArticle

  104. Evidence that CED-9/Bcl2 and CED-4/Apaf-1 localization is not consistent with the current model for C. elegans apoptosis induction

    Pourkarimi, E., Greiss, S. & Gartner, A. Mar 2012 In : Cell Death & Differentiation. 19, 3, p. 406-415 10 p.

    Research output: Contribution to journalArticle

  105. Scale integration: the structure and dynamics of macromolecular assemblies, cells and tissues

    Swedlow, J. & Danuser, G. 1 Feb 2012 In : Current Opinion in Cell Biology. 24, 1, p. 1-3 3 p.

    Research output: Contribution to journalArticle

  106. The dynamics of replication licensing in live Caenorhabditis elegans embryos

    Sonneville, R., Querenet, M., Craig, A., Gartner, A. & Blow, J. J. 23 Jan 2012 In : Journal of Cell Biology. 196, 2, p. 233-246 14 p.

    Research output: Contribution to journalArticle

  107. The shark in us: Learning about the evolution of the p53 regulatory circuit

    Rutkowski, R. & Gartner, A. 15 Jan 2012 In : Cell Cycle. 11, 2, p. 216-217 2 p.

    Research output: Contribution to journalComment/debate

  108. Detection and quantitation of SUMO chains by mass spectrometry

    Matic, I. & Hay, R. T. 1 Jan 2012 Ubiquitin family modifiers and the proteasome: reviews and protocols. Dohmen, R. J. & Scheffner, M. (eds.). Humana Press, p. 239-247 9 p. (Methods in molecular biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  109. Innovation in biological microscopy: current status and future directions

    Swedlow, J. R. 1 Jan 2012 In : BioEssays.

    Research output: Contribution to journalArticle

  110. Making sense of transcribing chromatin

    Owen-Hughes, T. & Gkikopoulos, T. 1 Jan 2012 In : Current Opinion in Cell Biology.

    Research output: Contribution to journalArticle

  111. Software tools, data structures, and interfaces for microscope imaging

    Stuurman, N. & Swedlow, J. R. 1 Jan 2012 In : Cold Spring Harbor Protocols. 7, 1, p. 50-61 12 p.

    Research output: Contribution to journalArticle

  112. Chromatin as an oxygen sensor and active player in the hypoxia response

    Melvin, A. & Rocha, S. Jan 2012 In : Cellular Signalling. 24, 1, p. 35-43 9 p.

    Research output: Contribution to journalScientific review

  113. hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: Structural and functional studies

    Drakou, C. E., Malekkou, A., Hayes, J. M., Lederer, C. W., Leonidas, D. D., Oikonomakos, N. G., Lamond, A. I., Santama, N. & Zographos, S. E. Jan 2012 In : Proteins: Structure, Function, and Bioinformatics. 80, 1, p. 206-220 15 p.

    Research output: Contribution to journalArticle

  114. Why are patients with small cell lung cancer (SCLC) not given chemotherapy?

    Khan, M. I., Brown, E. J., Lord, H., Allan, C., Sim, L., Buckle, F. & Rankin, E. M. Jan 2012 In : Lung Cancer. 75, p. S59-S59 1 p.

    Research output: Contribution to journalArticle

  115. ATP-independent cooperative binding of yeast Isw1a to bare and nucleosomal DNA

    De Cian, A., Praly, E., Ding, F., Singh, V., Lavelle, C., Le Cam, E., Croquette, V., Pietrement, O. & Bensimon, D. 2012 In : PLoS ONE. 7, 2, p. - 13 p.e31845

    Research output: Contribution to journalArticle

  116. Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore

    Bock, L. J., Pagliuca, C., Alfieri, C., Golfieri, C., Dal Maschio, M., De Wulf, P., Kobayashi, N., Oku, Y., Tanaka, T. U., Grove, R. A., Shrestha, K., Hazbun, T. R., Oldani, A. & Bermejo, R. 2012 In : Nature Cell Biology. 14, 6, p. 614-624 11 p.

    Research output: Contribution to journalArticle

  117. Cytosolic entry of shiga-like toxin a chain from the yeast endoplasmic reticulum requires catalytically active hrd1p

    Li, S., Spooner, R. A., Hampton, R. Y., Lord, J. M. & Roberts, L. M. 2012 In : PLoS ONE. 7, 7, e41119

    Research output: Contribution to journalArticle

  118. Highly potent activation of Nrf2 by topical tricyclic bis(cyano enone): Implications for protection against UV radiation during thiopurine therapy

    Kalra, S., Knatko, E. V., Zhang, Y., Honda, T., Yamamoto, M. & Dinkova-Kostova, A. T. 2012 In : Cancer Prevention Research. 5, 7, p. 973-981 9 p.

    Research output: Contribution to journalArticle

  119. Human papillomavirus-16 E5 protein: oncogenic role and therapeutic value

    Ganguly, N. 2012 In : Cellular Oncology. 35, 2, p. 67-76 10 p.

    Research output: Contribution to journalScientific review

  120. Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21

    de Wever, V., Lloyd, D. C., Nasa, I., Nimick, M., Trinkle-Mulcahy, L., Gourlay, R., Morrice, N. & Moorhead, G. B. G. 2012 In : PLoS ONE. 7, 6, e39510

    Research output: Contribution to journalArticle

  121. Isolation of NEDDylated proteins in human cells

    Leidecker, O. & Xirodimas, D. P. 2012 Ubiquitin family modifiers and the proteasome: reviews and protocols. Dohmen, R. J. & Scheffner, M. (eds.). Humana Press, p. 133-140 8 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  122. LAAT-1 is the lysosomal lysine/arginine transporter that maintains amino acid homeostasis

    Liu, B., Du, H., Rutkowski, R., Gartner, A. & Wang, X. 2012 In : Science. 337, 6092, p. 351-354 4 p.

    Research output: Contribution to journalArticle

  123. Live imaging of nascent RNA dynamics reveals distinct types of transcriptional pulse regulation

    Muramoto, T., Cannon, D., Gierlinski, M., Corrigan, A., Barton, G. J. & Chubb, J. R. 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 19, p. 7350-7355 6 p.

    Research output: Contribution to journalArticle

  124. Methods for studying the DNA damage response in the Caenorhabdatis elegans germ line

    Craig, A. L., Moser, S. C., Bailly, A. P. & Gartner, A. 2012 Caenorhabditis elegans: Cell Biology and Physiology. Rothman, J. H. & Singson, A. (eds.). Academic Press, Vol. 107, p. 321-352 32 p. (Methods in Cell Biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  125. Modulation of activation-associated host cell gene expression by the apicomplexan parasite Theileria annulata

    Durrani, Z., Weir, W., Pillai, S., Kinnaird, J. & Shiels, B. 2012 In : Cellular Microbiology.

    Research output: Contribution to journalArticle

  126. OMERO: Open source scientific image data management platform

    Swedlow, J. 2012

    Research output: Non-textual formSoftware

  127. Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway

    Arabi, A., Ullah, K., Branca, R. M. M., Johansson, J., Bandarra, D., Haneklaus, M., Fu, J., Ariës, I., Nilsson, P., Den Boer, M. L., Pokrovskaja, K., Grandér, D., Xiao, G., Rocha, S., Lehtiö, J. & Sangfelt, O. 2012 In : Nature Communications. 3, 976

    Research output: Contribution to journalArticle

  128. Quantitative proteomic analysis of yeast DNA replication proteins

    Kubota, T., Stead, D. A., Hiraga, S., ten Have, S. & Donaldson, A. D. 2012 In : Methods (San Diego, Calif.). 57, 2, p. 196-202 7 p.

    Research output: Contribution to journalArticle

  129. Raf1 is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modification

    Buscaino, A., White, S. A., Houston, D. R., Lejeune, E., Simmer, F., de Lima Alves, F., Diyora, P. T., Bayne, E. H., Rappsilber, J., Allshire, R. C. & Urano, T. 2012 In : PLoS Genetics. 8, 2, e1002499

    Research output: Contribution to journalArticle

  130. Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

    Plechanovová, A., Jaffray, E. G., Tatham, M. H., Naismith, J. H. & Hay, R. T. 2012 In : Nature. 489, 7414, p. 115-120 5 p.

    Research output: Contribution to journalArticle

  131. Sulfyhydryl-reactive site-directed cross-linking as a method for probing the tetrameric structure of histones H3 and H4

    Bowman, A. & Owen-Hughes, T. 2012 Chromatin remodeling: methods and protocols. Morse, R. H. (ed.). Humana Press, p. 373-387 15 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  132. The adenomatous polyposis Coli protein contributes to normal compaction of mitotic chromatin

    Dikovskaya, D., Khoudoli, G., Newton, I. P., Chadha, G. S., Klotz, D., Visvanathan, A., Lamond, A., Swedlow, J. R. & Nathke, I. S. 2012 In : PLoS ONE. 7, 6, e38102

    Research output: Contribution to journalArticle

  133. The Function of Snodprot in the Cerato-Platanin Family from Dactylellina cionopaga in Nematophagous Fungi

    Yu, H., Duan, J., Wang, B. & Jiang, X. 2012 In : Bioscience biotechnology and biochemistry. 76, 10, p. 1835-1842 8 p.

    Research output: Contribution to journalArticle

  134. The human T-lymphotropic virus type 1 tax protein inhibits nonsense-mediated mRNA decay by interacting with INT6/EIF3E and UPF1

    Mocquet, V., Neusiedler, J., Rende, F., Cluet, D., Robin, J-P., Terme, J-M., Dodon, M. D., Wittmann, J., Morris, C., Le Hir, H., Ciminale, V. & Jalinot, P. 2012 In : Journal of Virology. 86, 14, p. 7530-7543 14 p.

    Research output: Contribution to journalArticle

  135. The PHD and Chromo Domains Regulate the ATPase Activity of the Human Chromatin Remodeler CHD4

    Watson, A. A., Mahajan, P., Mertens, H. D. T., Deery, M. J., Zhang, W., Chen, Y., Edlich, C., Laue, E. D., Berridge, G., Burgess-Brown, N. A., Gileadi, O., Svergun, D. I., Pham, P., Du, X., Bartke, T., Kouzarides, T., Wiechens, N. & Owen-Hughes, T. 2012 In : Journal of Molecular Biology. 422, 1, p. 3-17 15 p.

    Research output: Contribution to journalArticle

  136. The serine/threonine kinase ULK1 is a target of multiple phosphorylation events

    Bach, M., Larance, M., James, D. E. & Ramm, G. 1 Dec 2011 In : Biochemical Journal. 440, 2, p. 283-291 9 p.

    Research output: Contribution to journalArticle

  137. Identification of RhoGAP22 as an Akt-dependent regulator of cell motility in response to insulin

    Rowland, A. F., Larance, M., Hughes, W. E. & James, D. E. Dec 2011 In : Molecular and Cellular Biology. 31, 23, p. 4789-4800 12 p.

    Research output: Contribution to journalArticle

  138. Kinetochore-Dependent Microtubule Rescue Ensures Their Efficient and Sustained Interactions in Early Mitosis

    Gandhi, S. R., Gierlinski, M., Mino, A., Tanaka, K., Kitamura, E., Clayton, L. & Tanaka, T. U. 15 Nov 2011 In : Developmental Cell. 21, 5, p. 920-933 14 p.

    Research output: Contribution to journalArticle

  139. Quantitative proteomic analysis of the adipocyte plasma membrane

    Prior, M. J., Larance, M., Lawrence, R. T., Soul, J., Humphrey, S., Burchfield, J., Kistler, C., Davey, J. R., La-Borde, P. J., Buckley, M., Kanazawa, H., Parton, R. G., Guilhaus, M. & James, D. E. 4 Nov 2011 In : Journal of Proteome Research. 10, 11, p. 4970-4982 13 p.

    Research output: Contribution to journalArticle

  140. From snoRNA to miRNA: Dual function regulatory non-coding RNAs

    Scott, M. S. & Ono, M. 1 Nov 2011 In : Biochimie. 93, 11, p. 1987-1992 6 p.

    Research output: Contribution to journalArticle

  141. The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH

    Melvin, A., Mudie, S. & Rocha, S. 1 Nov 2011 In : Molecular Biology of the Cell. 22, 21, p. 4171-4181 11 p.

    Research output: Contribution to journalArticle

  142. The Opportunistic Pathogen Serratia marcescens Utilizes Type VI Secretion To Target Bacterial Competitors

    Murdoch, S. L., Trunk, K., English, G., Fritsch, M. J., Pourkarimi, E. & Coulthurst, S. J. Nov 2011 In : Journal of Bacteriology. 193, 21, p. 6057-6069 13 p.

    Research output: Contribution to journalArticle

  143. CDC-48/p97 Coordinates CDT-1 Degradation with GINS Chromatin Dissociation to Ensure Faithful DNA Replication

    Franz, A., Orth, M., Pirson, P. A., Sonneville, R., Blow, J. J., Gartner, A., Stemmann, O. & Hoppe, T. 7 Oct 2011 In : Molecular Cell. 44, 1, p. 85-96 12 p.

    Research output: Contribution to journalArticle

  144. The breath between us

    Spence, P. & Rocha, S. 6 Oct 2011

    Research output: Non-textual formPerformance

  145. Absolute SILAC-compatible expression strain allows SUMO-2 copy number determination in clinical samples

    Matic, I., Jaffray, E. G., Oxenham, S. K., Groves, M. J., Barratt, C. L. R., Tauro, S., Stanley-Wall, N. R. & Hay, R. T. Oct 2011 In : Journal of Proteome Research. 10, 10, p. 4869-4875 7 p.

    Research output: Contribution to journalArticle

  146. An intranucleolar body associated with rDNA

    Hutten, S., Prescott, A., James, J., Riesenberg, S., Boulon, S., Lam, Y. W. & Lamond, A. I. Oct 2011 In : Chromosoma. 120, 5, p. 481-499 19 p.

    Research output: Contribution to journalArticle

  147. Mechanisms for ATP-dependent chromatin remodelling: the means to the end

    Flaus, A. & Owen-Hughes, T. Oct 2011 In : FEBS Journal. 278, 19, p. 3579-3595 17 p.

    Research output: Contribution to journalScientific review

  148. NF-kappa B controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration

    Mauro, C., Leow, S. C., Anso, E., Rocha, S., Thotakura, A. K., Tornatore, L., Moretti, M., De Smaele, E., Beg, A. A., Tergaonkar, V., Chandel, N. S. & Franzoso, G. Oct 2011 In : Nature Cell Biology. 13, 10, p. 1272-U234 18 p.

    Research output: Contribution to journalArticle

  149. Quantitative Proteomics and Dynamic Imaging of the Nucleolus Reveal Distinct Responses to UV and Ionizing Radiation

    Moore, H. M., Bai, B., Boisvert, F-M., Latonen, L., Rantanen, V., Simpson, J. C., Pepperkok, R., Lamond, A. I. & Laiho, M. Oct 2011 In : Molecular & Cellular Proteomics. 10, 10, p. - 15 p.M111.009241.

    Research output: Contribution to journalArticle

  150. Snf2-family proteins: chromatin remodellers for any occasion

    Ryan, D. P. & Owen-Hughes, T. Oct 2011 In : Current Opinion in Chemical Biology. 15, 5, p. 649-656 8 p.

    Research output: Contribution to journalScientific review

  151. Stable-isotope labeling with amino acids in nematodes

    Larance, M., Bailly, A. P., Pourkarimi, E., Hay, R. T., Buchanan, G., Coulthurst, S., Xirodimas, D. P., Gartner, A. & Lamond, A. I. Oct 2011 In : Nature Methods. 8, 10, p. 849-851 3 p.

    Research output: Contribution to journalArticle

  152. SUMOylation plays an essential role in human hepatocyte differentiation and cellular homeostasis

    Hannoun, Z., Jaffray, E., Greenhough, S., Medine, C. N., Forbes, S. J., Wilmut, I., Iredale, J. P., Hay, R. T. & Hay, D. C. Oct 2011 In : Hepatology. 54, S1, p. 958A-958A 1 p.

    Research output: Contribution to journalSpecial issue

  153. A role for Snf2-related nucleosome-spacing enzymes in genome-wide nucleosome organization

    Gkikopoulos, T., Schofield, P., Singh, V., Pinskaya, M., Mellor, J., Smolle, M., Workman, J. L., Barton, G. J. & Owen-Hughes, T. 23 Sep 2011 In : Science. 333, 6050, p. 1758-1760 3 p.

    Research output: Contribution to journalArticle

  154. TAF1B Is a TFIIB-Like Component of the Basal Transcription Machinery for RNA Polymerase I

    Naidu, S., Friedrich, J. K., Russell, J. & Zomerdijk, J. C. B. M. 16 Sep 2011 In : Science. 333, 6049, p. 1640-1642 3 p.

    Research output: Contribution to journalArticle

  155. LimsPortal and BonsaiLIMS: development of a lab information management system for translational medicine

    Bath, T. G., Bozdag, S., Afzal, V. & Crowther, D. 15 Sep 2011 In : Source code for biology and medicine. 6, p. 9

    Research output: Contribution to journalArticle

  156. The role of RelA (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration

    Msaki, A., Sanchez, A. M., Koh, L. F., Barre, B., Rocha, S., Perkins, N. D. & Johnson, R. F. 1 Sep 2011 In : Molecular Biology of the Cell. 22, 17, p. 3032-3040 9 p.

    Research output: Contribution to journalArticle

  157. Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity

    Sasaki, T., Li, A., Gillespie, P. J., Blow, J. J. & Gilbert, D. M. Sep 2011 In : Nucleus. 2, 5, p. 455-464

    Research output: Contribution to journalArticle

  158. In the family with ubiquitin

    Alexandru, G., Pariente, N. & Xirodimas, D. Sep 2011 In : EMBO Reports. 12, 9, p. 880-882 3 p.

    Research output: Contribution to journalEditorial

  159. Mechanism of ubiquitylation by dimeric RING ligase RNF4

    Plechanovova, A., Jaffray, E. G., McMahon, S. A., Johnson, K. A., Navratilova, I., Naismith, J. H. & Hay, R. T. Sep 2011 In : Nature Structural & Molecular Biology. 18, 9, p. 1052-1059 8 p.

    Research output: Contribution to journalArticle

  160. A novel reporter of notch signalling indicates regulated and random notch activation during vertebrate neurogenesis

    Vilas-Boas, F., Fior, R., Swedlow, J. R., Storey, K. G. & Henrique, D. 31 Aug 2011 In : BMC Molecular Biology. 9, p. - 16 p.58

    Research output: Contribution to journalArticle

  161. Exo70, a subunit of the exocyst complex, interacts with SNEVhPrp19/hPso4 and is involved in pre-mRNA splicing

    Dellago, H., Löscher , M., Ajuh, P., Ryder, U., Kaisermayer, C., Grillari-Voglauer, R., Fortschegger, K., Gross, S., Gstraunthaler, A., Borth, N., Eisenhaber, F., Lamond, A. I. & Grillari, J. 15 Aug 2011 In : Biochemical Journal. 438, p. 81-91 11 p.

    Research output: Contribution to journalArticle

  162. PChopper: high throughput peptide prediction for MRM/SRM transition design

    Afzal, V., Huang, J. T-J., Atrih, A. & Crowther, D. J. 15 Aug 2011 In : BMC Bioinformatics. 12, p. - 9 p.338

    Research output: Contribution to journalArticle

  163. OMX: a new platform for multimodal, multichannel wide-field imaging

    Dobbie, I. M., King, E., Parton, R. M., Carlton, P. M., Sedat, J. W., Swedlow, J. R. & Davis, I. 1 Aug 2011 In : Cold Spring Harbor Protocols. 6, 8, p. 899-909 11 p.

    Research output: Contribution to journalArticle

  164. Regulation of Caenorhabditis elegans p53/CEP-1-Dependent Germ Cell Apoptosis by Ras/MAPK Signaling

    Rutkowski, R., Dickinson, R., Stewart, G., Craig, A., Schimpl, M., Keyse, S. M. & Gartner, A. Aug 2011 In : PLoS Genetics. 7, 8, p. - 21 p.e1002238

    Research output: Contribution to journalArticle

  165. The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains

    Ryan, D. P., Sundaramoorthy, R., Martin, D., Singh, V. & Owen-Hughes, T. 6 Jul 2011 In : EMBO Journal. 30, 13, p. 2596-2609 14 p.

    Research output: Contribution to journalArticle

  166. Quantitative Proteomic Analysis of Chromatin Reveals that Ctf18 Acts in the DNA Replication Checkpoint

    Kubota, T., Hiraga, S., Yamada, K., Lamond, A. I. & Donaldson, A. D. Jul 2011 In : Molecular & Cellular Proteomics. 10, 7, p. - 14 p.M110.005561.

    Research output: Contribution to journalArticle

  167. Comparative proteomic analysis identifies a role for SUMO in protein quality control

    Tatham, M. H., Matic, I., Mann, M. & Hay, R. T. 21 Jun 2011 In : Science Signaling. 4, 178, p. - 12 p.rs4

    Research output: Contribution to journalArticle

  168. Erratum: Further insights into the mechanism of hypoxia-induced NFκB (Cell Cycle (2011) 10 (879-82))

    Melvin, A., Mudie, S. & Rocha, S. 15 Jun 2011 In : Cell Cycle. 10, 12, p. 2041 1 p.

    Research output: Contribution to journalArticle

  169. Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication

    Kundu, L. R., Seki, M., Watanabe, N., Murofushi, H., Furukohri, A., Waga, S., Score, A. J., Blow, J. J., Horikoshi, M., Enomoto, T. & Tada, S. Jun 2011 In : Biochimica et Biophysica Acta. Molecular Cell Research. 1813, 6, p. 1129-1136 8 p.

    Research output: Contribution to journalArticle

  170. Channeling the data deluge

    Swedlow, J. R., Zanetti, G. & Best, C. Jun 2011 In : Nature Methods. 8, 6, p. 463-465 3 p.

    Research output: Contribution to journalEditorial

  171. The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans

    Jannot, G., Bajan, S., Giguère, N. J., Bouasker, S., Banville, I. H., Piquet, S., Hutvagner, G. & Simard, M. J. Jun 2011 In : EMBO Reports. 12, 6, p. 581-586 6 p.

    Research output: Contribution to journalArticle

  172. The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4

    Gkikopoulos, T., Singh, V., Tsui, K., Awad, S., Renshaw, M. J., Scholfield, P., Barton, G. J., Nislow, C., Tanaka, T. U. & Owen-Hughes, T. 18 May 2011 In : EMBO Journal. 30, 10, p. 1919-1927 9 p.

    Research output: Contribution to journalArticle

  173. Antagonistic crosstalk between APC and HIF-1 alpha

    Nathke, I. & Rocha, S. 15 May 2011 In : Cell Cycle. 10, 10, p. 1545-1547 3 p.

    Research output: Contribution to journalArticle

  174. Identification of human miRNA precursors that resemble box C/D snoRNAs

    Ono, M., Scott, M. S., Yamada, K., Avolio, F., Barton, G. J. & Lamond, A. I. May 2011 In : Nucleic Acids Research. 39, 9, p. 3879-3891 13 p.

    Research output: Contribution to journalArticle

  175. A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1

    Narayan, V., Halada, P., Hernychová, L., Chong, Y. P., Žáková, J., Hupp, T. R., Vojtesek, B. & Ball, K. L. 22 Apr 2011 In : Journal of Biological Chemistry. 286, 16, p. 14291-14303 13 p.

    Research output: Contribution to journalArticle

  176. HIF-1 alpha depletion results in SP1-mediated cell cycle disruption and alters the cellular response to chemotherapeutic drugs

    Culver, C., Melvin, A., Mudie, S. & Rocha, S. 15 Apr 2011 In : Cell Cycle. 10, 8, p. 1249-1260 12 p.

    Research output: Contribution to journalArticle

  177. MCM2-7 Form Double Hexamers at Licensed Origins in Xenopus Egg Extract

    Gambus, A., Khoudoli, G. A., Jones, R. C. & Blow, J. J. 1 Apr 2011 In : Journal of Biological Chemistry. 286, 13, p. 11855-11864 10 p.

    Research output: Contribution to journalArticle

  178. A Screen for Novel Phosphoinositide 3-kinase Effector Proteins

    Dixon, M. J., Gray, A., Boisvert, F-M., Agacan, M., Morrice, N. A., Gourlay, R., Leslie, N. R., Downes, C. P. & Batty, I. H. Apr 2011 In : Molecular & Cellular Proteomics. 10, 4, p. - 13 p.003178

    Research output: Contribution to journalArticle

  179. An evolutionarily conserved, alternatively spliced, intron in the p68/DDX5 DEAD-box RNA helicase gene encodes a novel miRNA

    Moore, H. C., Johnston, M., Nicol, S. M., Bourdon, J-C., Thompson, A. M., Hutvagner, G. & Fuller-Pace, F. V. Apr 2011 In : RNA: a Publication of the RNA Society. 17, 4, p. 555-562 8 p.

    Research output: Contribution to journalArticle

  180. How to be a mitotic chromosome

    Moser, S. C. & Swedlow, J. R. Apr 2011 In : Chromosome Research. 19, 3, p. 307-319 13 p.

    Research output: Contribution to journalArticle

  181. Spatio-temporal modelling of the Hes1 and p53-Mdm2 intracellular signalling pathways

    Sturrock, M., Terry, A. J., Xirodimas, D. P., Thompson, A. M. & Chaplain, M. A. J. 21 Mar 2011 In : Journal of Theoretical Biology. 273, 1, p. 15-31 17 p.

    Research output: Contribution to journalArticle

  182. Mechanism of hypoxia-induced NFκB

    Melvin, A., Mudie, S. & Rocha, S. 15 Mar 2011 In : Cell Cycle. 10, 6, p. 879-882 4 p.

    Research output: Contribution to journalArticle

  183. Temperature-sensitive ipl1-2/Aurora B mutation is suppressed by mutations in TOR complex 1 via the Glc7/PP1 phosphatase

    Tatchell, K., Makrantoni, V., Stark, M. J. R. & Robinson, L. C. 8 Mar 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 10, p. 3994-3999 6 p.

    Research output: Contribution to journalArticle

  184. Functional interactions between ubiquitin E2 enzymes and TRIM proteins

    Napolitano, L. M., Jaffray, E. G., Hay, R. T. & Meroni, G. 1 Mar 2011 In : Biochemical Journal. 434, p. 309-319 11 p.

    Research output: Contribution to journalArticle

  185. Finding an image in a haystack: the case for public image repositories

    Swedlow, J. R. Mar 2011 In : Nature Cell Biology. 13, 3, p. 183-183 1 p.

    Research output: Contribution to journalEditorial

  186. Mass spectrometry-based immuno-precipitation proteomics - The user's guide

    ten Have, S., Boulon, S., Ahmad, Y. & Lamond, A. I. Mar 2011 In : Proteomics. 11, 6, p. 1153-1159 7 p.

    Research output: Contribution to journalArticle

  187. The histone chaperones Nap1 and Vps75 bind histones H3 and H4 in a tetrameric conformation

    Bowman, A., Ward, R., Wiechens, N., Singh, V., El-Mkami, H., Norman, D. G. & Owen-Hughes, T. 18 Feb 2011 In : Molecular Cell. 41, 4, p. 398-408 11 p.

    Research output: Contribution to journalArticle

  188. The Ndc80 Loop Region Facilitates Formation of Kinetochore Attachment to the Dynamic Microtubule Plus End

    Maure, J-F., Komoto, S., Oku, Y., Mino, A., Pasqualato, S., Natsume, K., Clayton, L., Musacchio, A. & Tanaka, T. U. 8 Feb 2011 In : Current Biology. 21, 3, p. 207-213 7 p.

    Research output: Contribution to journalArticle

  189. Nuclear Speckles

    Spector, D. L. & Lamond, A. I. Feb 2011 In : Cold Spring Harbor Perspectives in Biology. 3, 2, p. - 12 p.a000646

    Research output: Contribution to journalArticle

  190. Purification and identification of endogenous polySUMO conjugates

    Bruderer, R., Tatham, M. H., Plechanovova, A., Matic, I., Garg, A. K. & Hay, R. T. Feb 2011 In : EMBO Reports. 12, 2, p. 142-148 7 p.

    Research output: Contribution to journalArticle

  191. SUMO-modified nuclear cyclin D1 bypasses Ras-induced senescence

    Wang, X. D., Lapi, E., Sullivan, A., Ratnayaka, I., Goldin, R., Hay, R. & Lu, X. Feb 2011 In : Cell Death & Differentiation. 18, 2, p. 304-314 11 p.

    Research output: Contribution to journalArticle

  192. PNAC: a protein nucleolar association classifier

    Scott, M. S., Boisvert, F-M., Lamond, A. I. & Barton, G. J. 27 Jan 2011 In : BMC Genomics. 12, p. - 14 p.74

    Research output: Contribution to journalArticle

  193. RNA polymerase I-specific subunits promote polymerase clustering to enhance the rRNA gene transcription cycle

    Albert, B., Leger-Silvestre, I., Normand, C., Ostermaier, M. K., Perez-Fernandez, J., Panov, K. I., Zomerdijk, J. C. B. M., Schultz, P. & Gadal, O. 24 Jan 2011 In : Journal of Cell Biology. 192, 2, p. 277-293 17 p.

    Research output: Contribution to journalArticle

  194. DNA repair factor APLF is a histone chaperone

    Mehrotra, P. V., Ahel, D., Ryan, D. P., Weston, R., Wiechens, N., Kraehenbuehl, R., Owen-Hughes, T. & Ahel, I. 7 Jan 2011 In : Molecular Cell. 41, 1, p. 46-55 10 p.

    Research output: Contribution to journalArticle

  195. Docking-dependent ubiquitination of the interferon regulatory factor-1 tumor suppressor protein by the ubiquitin ligase CHIP

    Narayan, V., Pion, E., Landré, V., Müller, P. & Ball, K. L. 7 Jan 2011 In : Journal of Biological Chemistry. 286, 1, p. 607-619 13 p.

    Research output: Contribution to journalArticle

  196. A role for SUMOylation in snoRNP biogenesis revealed by quantitative proteomics

    Westman, B. J. & Lamond, A. I. 1 Jan 2011 In : Nucleus. 2, 1, p. 30-37 8 p.

    Research output: Contribution to journalArticle

  197. The dynamic proteome of the nucleolus

    Boisvert, F-M., Ahmad, Y. & Lamond, A. I. 1 Jan 2011 Protein Reviews. Vol. 15, p. 29-42 14 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  198. The SUMO protease SENP6 is a direct regulator of PML nuclear bodies

    Hattersley, N., Shen, L., Jaffray, E. G. & Hay, R. T. 1 Jan 2011 In : Molecular Biology of the Cell. 22, 1, p. 78-90 13 p.

    Research output: Contribution to journalArticle

  199. Evolutionary conserved regulation of HIF-1 beta by NF-kappa B

    van Uden, P., Kenneth, N. S., Webster, R., Muller, H. A., Mudie, S. & Rocha, S. Jan 2011 In : PLoS Genetics. 7, 1, p. - 15 p.e1001285

    Research output: Contribution to journalArticle

  200. Comparison of bipolar electrosurgical devices with ligatures and endoclips in the rat appendicitis model

    Elemen, L., Yazir, Y., Akay, A., Boyacioǧlu, Z., Ceyran, B. & Ceylan, S. 2011 In : Journal of Pediatric Surgery. 46, 10, p. 1923-1929 7 p.

    Research output: Contribution to journalArticle

  201. Using an argument ontology to develop pedagogical tool suites

    Reed, C., Wells, S., Snaith, M., Budzynska, K. & Lawrence, J. 2011 Tools for teaching logic: Third International Congress, TICTTL 2011 Salamanca, Spain, June 1-4, 2011. Proceedings. Blackburn, P., van Ditmarsch, H., Manzano, M. & Soler-Toscano, F. (eds.). Heidelberg: Springer, p. 207-214 8 p. (Lecture notes in computer science).

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  202. Post-translational modification by SUMO

    Hannoun, Z., Greenhough, S., Jaffray, E., Hay, R. T. & Hay, D. C. 30 Dec 2010 In : Toxicology. 278, 3, p. 288-293 6 p.

    Research output: Contribution to journalScientific review

  203. The effect of SUMO modification on hepatic differentiation from hESCs

    Hannoun, Z., Jaffray, E., Greenhough, S., Wilmut, I., Iredale, J. P., Hay, R. T. & Hay, D. C. 30 Dec 2010 In : Toxicology. 278, 3, p. 352-352 1 p.

    Research output: Contribution to journalBook/Film/Article review

  204. Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories

    Ge, X. Q. & Blow, J. J. 27 Dec 2010 In : Journal of Cell Biology. 191, 7, p. 1285-1297 13 p.

    Research output: Contribution to journalArticle

  205. Natural variation of the amino-terminal glutamine-rich domain in Drosophila argonaute2 is not associated with developmental defects

    Hain, D., Bettencourt, B. R., Okamura, K., Csorba, T., Meyer, W., Jin, Z., Biggerstaff, J., Siomi, H., Hutvagner, G., Lai, E. C., Welte, M. & Muller, H-A. J. 16 Dec 2010 In : PLoS ONE. 5, 12, p. - 14 p.e15264

    Research output: Contribution to journalArticle

  206. Kinetochore-microtubule interactions: steps towards bi-orientation

    Tanaka, T. U. 15 Dec 2010 In : EMBO Journal. 29, 24, p. 4070-4082 13 p.

    Research output: Contribution to journalScientific review

  207. Intracellular activation of interferon regulatory factor-1 by nanobodies to the multifunctional (Mf1) domain

    Möller, A., Pion, E., Narayan, V. & Ball, K. L. 3 Dec 2010 In : Journal of Biological Chemistry. 285, 49, p. 38348-38361 14 p.

    Research output: Contribution to journalArticle

  208. Arsenic-induced SUMO-dependent recruitment of RNF4 into PML nuclear bodies

    Geoffroy, M-C., Jaffray, E. G., Walker, K. J. & Hay, R. T. 1 Dec 2010 In : Molecular Biology of the Cell. 21, 23, p. 4227-4239 13 p.

    Research output: Contribution to journalArticle

  209. RRP1B Targets PP1 to Mammalian Cell Nucleoli and Is Associated with Pre-60S Ribosomal Subunits

    Chamousset, D., De Wever, V., Moorhead, G. B., Chen, Y., Boisvert, F-M., Lamond, A. I. & Trinkle-Mulcahy, L. 1 Dec 2010 In : Molecular Biology of the Cell. 21, 23, p. 4212-4226 15 p.

    Research output: Contribution to journalArticle

  210. The nuclear ATPase/adenylate kinase hCINAP is recruited to perinucleolar caps generated upon RNA pol.II inhibition

    Malekkou, A., Lederer, C. W., Lamond, A. I. & Santama, N. 19 Nov 2010 In : FEBS Letters. 584, 22, p. 4559-4564 6 p.

    Research output: Contribution to journalArticle

  211. Adenomatous polyposis coli and hypoxia-inducible factor-1 alpha have an antagonistic connection

    Newton, I. P., Kenneth, N. S., Appleton, P. L., Nathke, I. & Rocha, S. 1 Nov 2010 In : Molecular Biology of the Cell. 21, 21, p. 3630-3638 9 p.

    Research output: Contribution to journalArticle

  212. High-resolution whole-genome sequencing reveals that specific Chromatin Domains from most human chromosomes associate with nucleoli

    van Koningsbruggen, S., Gierlinski, M., Schofield, P., Martin, D., Barton, G. J., Ariyurek, Y., den Dunnen, J. T. & Lamond, A. I. 1 Nov 2010 In : Molecular Biology of the Cell. 21, 21, p. 3735-3748 14 p.

    Research output: Contribution to journalArticle

  213. Characterization and prediction of protein nucleolar localization sequences

    Scott, M. S., Boisvert, F-M., McDowall, M. D., Lamond, A. I. & Barton, G. J. Nov 2010 In : Nucleic Acids Research. 38, 21, p. 7388-7399 12 p.

    Research output: Contribution to journalArticle

  214. EPR distance measurements in deuterated proteins

    Ward, R., Bowman, A., Sozudogru, E., El-Mkami, H., Owen-Hughes, T. & Norman, D. G. Nov 2010 In : Journal of Magnetic Resonance Imaging. 207, 1, p. 164-167 4 p.

    Research output: Contribution to journalArticle

  215. p53-Dependent subcellular proteome localization following DNA damage

    Boisvert, F-M. & Lamond, A. I. Nov 2010 In : Proteomics. 10, 22, p. 4087-4097 11 p.

    Research output: Contribution to journalArticle

  216. SUMOylation of the GTPase Rac1 is required for optimal cell migration

    Castillo-Lluva, S., Tatham, M. H., Jones, R. C., Jaffray, E. G., Edmondson, R. D., Hay, R. T. & Malliri, A. Nov 2010 In : Nature Cell Biology. 12, 11, p. 1078-U70 21 p.

    Research output: Contribution to journalArticle

  217. ATRX: put me on repeat

    Whitehouse, I. & Owen-Hughes, T. 29 Oct 2010 In : Cell. 143, 3, p. 335-336 2 p.

    Research output: Contribution to journalEditorial

  218. Regulation of miRNA transcription in macrophages in response to Candida albicans

    Monk, C. E., Hutvagner, G. & Arthur, J. S. C. 27 Oct 2010 In : PLoS ONE. 5, 10, p. - 12 p.e13669

    Research output: Contribution to journalArticle

  219. The Nucleolus under Stress

    Boulon, S., Westman, B. J., Hutten, S., Boisvert, F-M. & Lamond, A. I. 22 Oct 2010 In : Molecular Cell. 40, 2, p. 216-227 12 p.

    Research output: Contribution to journalScientific review

  220. p53-dependent repression of polo-like kinase-1 (PLK1)

    McKenzie, L., King, S., Marcar, L., Nicol, S., Dias, S., Schumm, K., Robertson, P., Bourdon, J-C., Perkins, N., Fuller-Pace, F. & Meek, D. W. 15 Oct 2010 In : Cell Cycle. 9, 20, p. 4200-4212 13 p.

    Research output: Contribution to journalArticle

  221. Mechanism of Hypoxia-Induced NF-kappa B

    Culver, C., Sundqvist, A., Mudie, S., Melvin, A., Xirodimas, D. & Rocha, S. 10 Oct 2010 In : Molecular and Cellular Biology. 30, 20, p. 4901-4921 21 p.

    Research output: Contribution to journalArticle

  222. Sds22 regulates aurora B activity and microtubule-kinetochore interactions at mitosis

    Posch, M., Khoudoli, G. A., Swift, S., King, E. M., DeLuca, J. G. & Swedlow, J. R. 4 Oct 2010 In : Journal of Cell Biology. 191, 1, p. 61-74 14 p.

    Research output: Contribution to journalArticle

  223. HSP90 and Its R2TP/Prefoldin-like Cochaperone Are Involved in the Cytoplasmic Assembly of RNA Polymerase II

    Boulon, S., Pradet-Balade, B., Verheggen, C., Molle, D., Boireau, S., Georgieva, M., Azzag, K., Robert, M-C., Ahmad, Y., Neel, H., Lamond, A. I. & Bertrand, E. 24 Sep 2010 In : Molecular Cell. 39, 6, p. 912-924 13 p.

    Research output: Contribution to journalArticle

  224. Advanced hardware and software tools for fast multidimensional imaging of living cells

    Swedlow, J. R. 14 Sep 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 37, p. 16005-16006 2 p.

    Research output: Contribution to journalEditorial

  225. The serine/arginine-rich protein SF2/ASF regulates protein sumoylation

    Pelisch, F., Gerez, J., Druker, J., Schor, I. E., Munoz, M. J., Risso, G., Petrillo, E., Westman, B. J., Lamond, A. I., Arzt, E. & Srebrow, A. 14 Sep 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 37, p. 16119-16124 6 p.

    Research output: Contribution to journalArticle

  226. IKK and NF-kappa B-mediated regulation of Claspin impacts on ATR checkpoint function

    Kenneth, N. S., Mudie, S. & Rocha, S. 1 Sep 2010 In : EMBO Journal. 29, 17, p. 2966-2978 13 p.

    Research output: Contribution to journalArticle

  227. Live-cell imaging RNAi screen identifies PP2A-B55 alpha and importin-beta 1 as key mitotic exit regulators in human cells

    Schmitz, M. H. A., Held, M., Janssens, V., Hutchins, J. R. A., Hudecz, O., Ivanova, E., Goris, J., Trinkle-Mulcahy, L., Lamond, A. I., Poser, I., Hyman, A. A., Mechtler, K., Peters, J-M. & Gerlich, D. W. Sep 2010 In : Nature Cell Biology. 12, 9, p. 886-893 8 p.

    Research output: Contribution to journalArticle

  228. The "Mutated in Colorectal Cancer" Protein Is a Novel Target of the UV-Induced DNA Damage Checkpoint

    Pangon, L., Sigglekow, N. D., Larance, M., Al-Sohaily, S., Mladenova, D. N., Selinger, C. I., Musgrove, E. A. & Kohonen-Corish, M. R. J. Sep 2010 In : Genes and Cancer. 1, 9, p. 917-926 10 p.

    Research output: Contribution to journalArticle

  229. A Proteomic Screen for Nucleolar SUMO Targets Shows SUMOylation Modulates the Function of Nop5/Nop58

    Westman, B. J., Verheggen, C., Hutten, S., Lam, Y. W., Bertrand, E. & Lamond, A. I. 27 Aug 2010 In : Molecular Cell. 39, 4, p. 618-631 14 p.

    Research output: Contribution to journalArticle

  230. Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif

    Matic, I., Schimmel, J., Hendriks, I. . A., van Santen, M. A., van de Rijke, F., van Dam, H., Gnad, F., Mann, M. & Vertegaal, A. C. O. 27 Aug 2010 In : Molecular Cell. 39, 4, p. 641-652 12 p.

    Research output: Contribution to journalArticle

  231. Condensins Promote Chromosome Recoiling during Early Anaphase to Complete Sister Chromatid Separation

    Renshaw, M. J., Ward, J. J., Kanemaki, M., Natsume, K., Nedelec, F. J. & Tanaka, T. U. 17 Aug 2010 In : Developmental Cell. 19, 2, p. 232-244 13 p.

    Research output: Contribution to journalArticle

  232. Clusters, factories and domains: The complex structure of S-phase comes into focus

    Gillespie, P. J. & Blow, J. 15 Aug 2010 In : Cell Cycle. 9, 16, p. 3218-3226 9 p.

    Research output: Contribution to journalArticle

  233. Identification of KIAA1018/FAN1, a DNA Repair Nuclease Recruited to DNA Damage by Monoubiquitinated FANCD2

    MacKay, C., Declais, A-C., Lundin, C., Agostinho, A., Deans, A. J., MacArtney, T. J., Hofmann, K., Gartner, A., West, S. C., Helleday, T., Lilley, D. M. J. & Rouse, J. 9 Jul 2010 In : Cell. 142, 1, p. 65-76 12 p.

    Research output: Contribution to journalArticle

  234. Paraspeckles

    Fox, A. H. & Lamond, A. I. Jul 2010 In : Cold Spring Harbor Perspectives in Biology. 2, 7, p. - 14 p.a000687

    Research output: Contribution to journalArticle

  235. Phylogeny and Function of the Invertebrate p53 Superfamily

    Rutkowski, R., Hofmann, K. & Gartner, A. Jul 2010 In : Cold Spring Harbor Perspectives in Biology. 2, 7, p. - 13 p.a001131

    Research output: Contribution to journalArticle

  236. Tagging the dead: a bridging factor for Caenorhabditis elegans phagocyte receptors

    Rutkowski, R. & Gartner, A. Jul 2010 In : Nature Cell Biology. 12, 7, p. 638-640 4 p.

    Research output: Contribution to journalEditorial

  237. The Caenorhabditis elegans Homolog of Gen1/Yen1 Resolvases Links DNA Damage Signaling to DNA Double-Strand Break Repair

    Bailly, A. P., Freeman, A., Hall, J., Declais, A-C., Alpi, A., Lilley, D. M. J., Ahmed, S. & Gartner, A. Jul 2010 In : PLoS Genetics. 6, 7, p. - 16 p.e1001025

    Research output: Contribution to journalArticle

  238. Determinants of Myosin II Cortical Localization during Cytokinesis

    Uehara, R., Goshima, G., Mabuchi, I., Vale, R. D., Spudich, J. A. & Griffis, E. R. 22 Jun 2010 In : Current Biology. 20, 12, p. 1080-1085 6 p.

    Research output: Contribution to journalArticle

  239. Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins

    Remenyi, J., Hunter, C. J., Cole, C., Ando, H., Impey, S., Monk, C. E., Martin, K. J., Barton, G. J., Hutvagner, G. & Arthur, J. S. C. 1 Jun 2010 In : Biochemical Journal. 428, 2, p. 281-291 11 p.

    Research output: Contribution to journalArticle

  240. Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice

    Lleres, D., Denegri, M., Biggiogera, M., Ajuh, P. & Lamond, A. I. Jun 2010 In : EMBO Reports. 11, 6, p. 445-451 7 p.

    Research output: Contribution to journalArticle

  241. Metadata matters: access to image data in the real world

    Linkert, M., Rueden, C. T., Allan, C., Burel, J-M., Moore, W., Patterson, A., Loranger, B., Moore, J., Neves, C., MacDonald, D., Tarkowska, A., Sticco, C., Hill, E., Rossner, M., Eliceiri, K. W. & Swedlow, J. R. 31 May 2010 In : Journal of Cell Biology. 189, 5, p. 777-782 6 p.

    Research output: Contribution to journalEditorial

  242. Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK

    Li, X., Vadrevu, S., Dunlop, A., Day, J., Advant, N., Troeger, J., Klussmann, E., Jaffray, E., Hay, R. T., Adams, D. R., Houslay, M. D. & Baillie, G. S. 15 May 2010 In : Biochemical Journal. 428, p. 55-65 11 p.

    Research output: Contribution to journalArticle

  243. Nuclear DBF-2-related Kinases Are Essential Regulators of Cytokinesis in Bloodstream Stage Trypanosoma brucei

    Ma, J., Benz, C., Grimaldi, R., Stockdale, C., Wyatt, P., Frearson, J. & Hammarton, T. C. 14 May 2010 In : Journal of Biological Chemistry. 285, 20, p. 15356-15368 13 p.

    Research output: Contribution to journalArticle

  244. Analysis of Human Small Nucleolar RNAs (snoRNA) and the Development of snoRNA Modulator of Gene Expression Vectors

    Ono, M., Yamada, K., Avolio, F., Scott, M. S., van Koningsbruggen, S., Barton, G. J. & Lamond, A. I. 1 May 2010 In : Molecular Biology of the Cell. 21, 9, p. 1569-1584 16 p.

    Research output: Contribution to journalArticle

  245. HSP90 protein stabilizes unloaded Argonaute complexes and microscopic P-bodies in human cells

    Johnston, M., Geoffroy, M-C., Sobala, A., Hay, R. & Hutvagner, G. 1 May 2010 In : Molecular Biology of the Cell. 21, 9, p. 1462-1469 8 p.

    Research output: Contribution to journalArticle

  246. Establishment of a protein frequency library and its application in the reliable identification of specific protein interaction partners

    Boulon, S., Ahmad, Y., Trinkle-Mulcahy, L., Verheggen, C., Cobley, A., Gregor, P., Bertrand, E., Whitehorn, M. & Lamond, A. I. May 2010 In : Molecular & Cellular Proteomics. 9, 5, p. 861-879 19 p.

    Research output: Contribution to journalArticle

  247. Oligomerization conditions Mdm2-mediated efficient p53 polyubiquitylation but not its proteasomal degradation

    Hjerpe, R., Aillet, F., Lopitz-Otsoa, F., Lang, V., Torres-Ramos, M., Farras, R., Hay, R. T. & Rodriguez, M. S. May 2010 In : International Journal of Biochemistry & Cell Biology. 42, 5, p. 725-735 11 p.

    Research output: Contribution to journalArticle

  248. Cell biology forum: genome-wide view of mitosis

    Swedlow, J. R., Cotta-Ramusino, C. & Elledge, S. J. 1 Apr 2010 In : Nature. 464, 7289, p. 684-685 2 p.

    Research output: Contribution to journalEditorial

  249. Global phosphoproteomics identifies a major role for AKT and 14-3-3 in regulating EDC3

    Larance, M., Rowland, A. F., Hoehn, K. L., Humphreys, D. T., Preiss, T., Guilhaus, M. & James, D. E. Apr 2010 In : Molecular & Cellular Proteomics. 9, 4, p. 682-694 13 p.

    Research output: Contribution to journalArticle

  250. The Snf2 Homolog Fun30 acts as a homodimeric ATP-dependent chromatin-remodeling enzyme

    Awad, S., Ryan, D., Prochasson, P., Owen-Hughes, T. & Hassan, A. H. 26 Mar 2010 In : Journal of Biological Chemistry. 285, 13, p. 9477-9484 8 p.

    Research output: Contribution to journalArticle

  251. Methylation of H3K4 is required for inheritance of active transcriptional states

    Muramoto, T., Mueller, I., Thomas, G., Melvin, A. & Chubb, J. R. 9 Mar 2010 In : Current Biology. 20, 5, p. 397-406 10 p.

    Research output: Contribution to journalArticle

  252. Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases

    Jaqaman, K., King, E. M., Amaro, A. C., Winter, J. R., Dorn, J. F., Elliott, H. L., Mchedlishvili, N., McClelland, S. E., Porter, I. M., Posch, M., Toso, A., Danuser, G., McAinsh, A. D., Meraldi, P. & Swedlow, J. R. 8 Mar 2010 In : Journal of Cell Biology. 188, 5, p. 665-679 15 p.

    Research output: Contribution to journalArticle

  253. Stc1: A Critical Link between RNAi and Chromatin Modification Required for Heterochromatin Integrity

    Bayne, E. H., White, S. A., Kagansky, A., Bijos, D. A., Sanchez-Pulido, L., Hoe, K-L., Kim, D-U., Park, H-O., Ponting, C. P., Rappsilber, J. & Allshire, R. C. 5 Mar 2010 In : Cell. 140, 5, p. 666-677 12 p.

    Research output: Contribution to journalArticle

  254. Microtubule assembly by the Apc protein is regulated by importin-beta-RanGTP

    Dikovskaya, D., Li, Z., Newton, I. P., Davidson, I., Hutchins, J. R. A., Kalab, P., Clarke, P. R. & Nathke, I. S. 1 Mar 2010 In : Journal of Cell Science. 123, 5, p. 736-746 11 p.

    Research output: Contribution to journalArticle

  255. A Quantitative Proteomics Analysis of Subcellular Proteome Localization and Changes Induced by DNA Damage

    Boisvert, F-M., Lam, Y. W., Lamont, D. & Lamond, A. I. Mar 2010 In : Molecular & Cellular Proteomics. 9, 3, p. 457-470 14 p.

    Research output: Contribution to journalArticle

  256. Cell-Nonautonomous Regulation of C. elegans Germ Cell Death by kri-1

    Ito, S., Greiss, S., Gartner, A. & Derry, W. B. 23 Feb 2010 In : Current Biology. 20, 4, p. 333-338 6 p.

    Research output: Contribution to journalArticle

  257. Kinetochores Generate Microtubules with Distal Plus Ends: Their Roles and Limited Lifetime in Mitosis

    Kitamura, E., Tanaka, K., Komoto, S., Kitamura, Y., Antony, C. & Tanaka, T. U. 16 Feb 2010 In : Developmental Cell. 18, 2, p. 248-259 12 p.

    Research output: Contribution to journalArticle

  258. Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP

    Fogarty, S., Hawley, S. A., Green, K. A., Saner, N., Mustard, K. J. & Hardie, D. G. 15 Feb 2010 In : Biochemical Journal. 426, p. 109-118 10 p.

    Research output: Contribution to journalArticle

  259. Modelling contact spread of infection in host-parasitoid systems: Vertical transmission of pathogens can cause chaos

    Preedy, K. F., Schofield, P. G., Liu, S., Matzavinos, A., Chaplain, M. A. J. & Hubbard, S. F. 7 Feb 2010 In : Journal of Theoretical Biology. 262, 3, p. 441-451 11 p.

    Research output: Contribution to journalArticle

  260. Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels

    Thomson, A. M., Gillespie, P. J. & Blow, J. J. 25 Jan 2010 In : Journal of Cell Biology. 188, 2, p. 209-221 13 p.

    Research output: Contribution to journalArticle

  261. Histone Acetylation by HBO1 Tightens Replication Licensing

    Chadha, G. S. & Blow, J. J. 15 Jan 2010 In : Molecular Cell. 37, 1, p. 5-6 2 p.

    Research output: Contribution to journalEditorial

  262. Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity

    Hoehn, K. L., Turner, N., Swarbrick, M. M., Wilks, D., Preston, E., Phua, Y., Joshi, H., Furler, S. M., Larance, M., Hegarty, B. D., Leslie, S. J., Pickford, R., Hoy, A. J., Kraegen, E. W., James, D. E. & Cooney, G. J. 6 Jan 2010 In : Cell Metabolism. 11, 1, p. 70-76 7 p.

    Research output: Contribution to journalArticle

  263. On the connection between RNAi and heterochromatin at centromeres

    Lejeune, E., Bayne, E. H. & Allshire, R. C. 1 Jan 2010 In : Cold Spring Harbor Symposia on Quantitative Biology. 75, p. 275-283 9 p.

    Research output: Contribution to journalArticle

  264. Probing the (H3-H4)(2) histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling

    Bowman, A., Ward, R., El-Mkami, H., Owen-Hughes, T. & Norman, D. G. Jan 2010 In : Nucleic Acids Research. 38, 2, p. 695-707 13 p.

    Research output: Contribution to journalArticle

  265. Spatial regulation and organization of DNA replication within the nucleus

    Natsume, T. & Tanaka, T. U. Jan 2010 In : Chromosome Research. 18, 1, p. 7-17 11 p.

    Research output: Contribution to journalArticle

  266. The Caenorhabditis elegans Werner Syndrome Protein functions upstream of ATR and ATM in response to DNA Replication Inhibition and Double-Strand DNA Breaks

    Lee, S-J., Gartner, A., Hyun, M., Ahn, B. & Koo, H-S. Jan 2010 In : PLoS Genetics. 6, 1, p. - 11 p.e1000801

    Research output: Contribution to journalArticle

  267. Building arguments with argumentation: the role of illocutionary force in computational models of argument

    Reed, C., Wells, S., Budzynska, K. & Devereux, J. 2010 Computational Models of Argument : proceedings of COMMA 2010. Baroni, P., Cerutti, F., Giacomin, M. & Simari, G. R. (eds.). Amsterdam: IOS Press, p. 415-426 12 p. (Frontiers in artificial intelligence and applications).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  268. Building arguments with argumentation: the role of illocutionary force in computational models of argument

    Reed, C., Wells, S., Budzynska, K. & Devereux, J. 2010

    Research output: Contribution to conferencePaper

  269. High-stringency tandem affinity purification of proteins conjugated to ubiquitin-like moieties

    Golebiowski, F., Tatham, M. H., Nakamura, A. & Hay, R. T. 2010 In : Nature Protocols. 5, 5, p. 873-882 10 p.

    Research output: Contribution to journalArticle

  270. Involvement of the nuclear cap-binding protein complex in alternative splicing in Arabidopsis thaliana

    Raczynska, K. D., Simpson, C. G., Ciesiolka, A., Szewc, L., Lewandowska, D., McNicol, J., Szweykowska-Kulinska, Z., Brown, J. W. S. & Jarmolowski, A. 2010 In : Nucleic Acids Research. 38, 1, p. 265-278 14 p.

    Research output: Contribution to journalArticle

  271. LigaSure compared with ligatures and endoclips in experimental appendectomy: How safe is it?

    Elemen, L., Tugay, M., Akay, A., Yazir, Y., Ceylan, S., Aydin, S. & Yanar, K. 2010 In : Pediatric Surgery International. 26, 5, p. 539-545 7 p.

    Research output: Contribution to journalArticle

  272. Live-cell analysis of kinetochore-microtubule interaction in budding yeast

    Tanaka, K., Kitamura, E. & Tanaka, T. U. 2010 In : Methods (San Diego, Calif.). 51, 2, p. 206-13 8 p.

    Research output: Contribution to journalArticle

  273. p53 and immunity

    Narayan, V., Meek, S. E. M. & Ball, K. 2010 p53. Ayed, A. & Hupp, T. (eds.). Austin, TX: Landes Bioscience, p. 178-186 9 p. (Molecular Biology Intelligence Unit).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  274. Proteomics Analysis of the Nucleolus in Adenovirus-infected Cells

    Lam, Y. W., Evans, V. C., Heesom, K. J., Lamond, A. I. & Matthews, D. A. 2010 In : Molecular & Cellular Proteomics. 9, 1, p. 117-130 14 p.

    Research output: Contribution to journalArticle

  275. Analysis of small RNA in fission yeast; centromeric siRNAs are potentially generated through a structured RNA

    Djupedal, I., Kos-Braun, I. C., Mosher, R. A., Soderholm, N., Simmer, F., Hardcastle, T. J., Fender, A., Heidrich, N., Kagansky, A., Bayne, E., Wagner, E. G. H., Baulcombe, D. C., Allshire, R. C. & Ekwall, K. 16 Dec 2009 In : EMBO Journal. 28, 24, p. 3832-3844 13 p.

    Research output: Contribution to journalArticle

  276. The Nup107-160 nucleoporin complex promotes mitotic events via control of the localization state of the chromosome passenger complex

    Platani, M., Santarella-Mellwig, R., Posch, M., Walczak, R., Swedlow, J. R. & Mattaj, I. W. 15 Dec 2009 In : Molecular Biology of the Cell. 20, 24, p. 5260-5275 16 p.

    Research output: Contribution to journalArticle

  277. Ipl1-dependent phosphorylation of Dam1 is reduced by tension applied on kinetochores

    Keating, P., Rachidi, N., Tanaka, T. U. & Stark, M. J. R. 1 Dec 2009 In : Journal of Cell Science. 122, 23, p. 4375-4382 8 p.

    Research output: Contribution to journalArticle

  278. Cell fate decisions are specified by the dynamic ERK interactome

    von Kriegsheim, A., Baiocchi, D., Birtwistle, M., Sumpton, D., Bienvenut, W., Morrice, N., Yamada, K., Lamond, A., Kalna, G., Orton, R., Gilbert, D. & Kolch, W. Dec 2009 In : Nature Cell Biology. 11, 12, p. 1458-1464 7 p.

    Research output: Contribution to journalArticle

  279. Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs

    Cole, C., Sobala, A., Lu, C., Thatcher, S. R., Bowman, A., Brown, J. W. S., Green, P. J., Barton, G. J. & Hutvagner, G. Dec 2009 In : RNA: a Publication of the RNA Society. 15, 12, p. 2147-2160 14 p.

    Research output: Contribution to journalArticle

  280. The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegans

    Meier, B., Barber, L. J., Liu, Y., Shtessel, L., Boulton, S. J., Gartner, A. & Ahmed, S. 18 Nov 2009 In : EMBO Journal. 28, 22, p. 3549-3563 15 p.

    Research output: Contribution to journalArticle

  281. Quantitative analysis of chromatin compaction in living cells using FLIM-FRET

    Lleres, D., James, J., Swift, S., Norman, D. G. & Lamond, A. I. 16 Nov 2009 In : Journal of Cell Biology. 187, 4, p. 481-496 16 p.

    Research output: Contribution to journalArticle

  282. Distinct subsets of Sit4 holophosphatases are required for inhibition of saccharomyces cerevisiae growth by rapamycin and zymocin

    Jablonowski, D., Taeubert, J-E., Baer, C., Stark, M. J. R. & Schaffrath, R. Nov 2009 In : Eukaryotic Cell. 8, 11, p. 1637-1647 11 p.

    Research output: Contribution to journalArticle

  283. Iso-seco-tanapartholides: isolation, synthesis and biological evaluation

    Makiyi, E. F., Frade, R. F. M., Lebl, T., Jaffray, E. G., Cobb, S. E., Harvey, A. L., Slawin, A. M. Z., Hay, R. T. & Westwood, N. J. Nov 2009 In : European Journal of Organic Chemistry. 33, p. 5711-5715 5 p.

    Research output: Contribution to journalArticle

  284. Open source bioimage informatics for cell biology

    Swedlow, J. R. & Eliceiri, K. W. Nov 2009 In : Trends in Cell Biology. 19, 11, p. 656-660 5 p.

    Research output: Contribution to journalScientific review

  285. p38 alpha- and DYRK1A-dependent phosphorylation of caspase-9 at an inhibitory site in response to hyperosmotic stress

    Seifert, A. & Clarke, P. R. Nov 2009 In : Cellular Signalling. 21, 11, p. 1626-1633 8 p.

    Research output: Contribution to journalArticle

  286. Sirtuin/Sir2 phylogeny, evolutionary considerations and structural conservation

    Greiss, S. & Gartner, A. Nov 2009 In : Molecules and Cells. 28, 5, p. 407-415 9 p.

    Research output: Contribution to journalScientific review

  287. Blom7 alpha Is a Novel Heterogeneous Nuclear Ribonucleoprotein K Homology Domain Protein Involved in Pre-mRNA Splicing That Interacts with SNEVPrp19-Pso4

    Grillari, J., Löscher , M., Denegri, M., Lee, K., Fortschegger, K., Eisenhaber, F., Ajuh, P., Lamond, A. I., Katinger, H. & Grillari-Voglauer, R. 16 Oct 2009 In : Journal of Biological Chemistry. 284, 42, p. 29193-29204 12 p.

    Research output: Contribution to journalArticle

  288. A method for genetically installing site-specific acetylation in recombinant histories defines the effects of H3 K56 acetylation

    Neumann, H., Hancock, S. M., Buning, R., Routh, A., Chapman, L., Somers, J., Owen-Hughes, T., van Noort, J., Rhodes, D. & Chin, J. W. 9 Oct 2009 In : Molecular Cell. 36, 1, p. 153-163 11 p.

    Research output: Contribution to journalArticle

  289. A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome

    Gambus, A., van Deursen, F., Polychronopoulos, D., Foltman, M., Jones, R. C., Edmondson, R. D., Calzada, A. & Labib, K. 7 Oct 2009 In : EMBO Journal. 28, 19, p. 2992-3004 13 p.

    Research output: Contribution to journalArticle

  290. Role of the IRF-1 enhancer domain in signalling polyubiquitination and degradation

    Pion, E., Narayan, V., Eckert, M. & Ball, K. L. Oct 2009 In : Cellular Signalling. 21, 10, p. 1479-1487 9 p.

    Research output: Contribution to journalArticle

  291. Cooperative regulation of the interferon regulatory factor-1 tumor suppressor protein by core components of the molecular chaperone machinery

    Narayan, V., Eckert, M., Zylicz, A., Zylicz, M. & Ball, K. L. 18 Sep 2009 In : Journal of Biological Chemistry. 284, 38, p. 25889-25899 11 p.

    Research output: Contribution to journalArticle

  292. Dynamic localisation of Ran GTPase during the cell cycle

    Hutchins, J. R. A., Moore, W. J. & Clarke, P. R. 18 Sep 2009 In : BMC Cell Biology. 10, p. - 10 p.66

    Research output: Contribution to journalArticle

  293. Mutations of NFKBIA, encoding I kappa B alpha, are a recurrent finding in classical Hodgkin lymphoma but are not a unifying feature of non-EBV-associated cases

    Lake, A., Shield, L. A., Cordano, P., Chui, D. T. Y., Osborne, J., Crae, S., Wilson, K. S., Tosi, S., Knight, S. J. L., Gesk, S., Siebert, R., Hay, R. T. & Jarrett, R. F. 15 Sep 2009 In : International Journal of Cancer. 125, 6, p. 1334-1342 9 p.

    Research output: Contribution to journalArticle

  294. Dynamics of myosin, microtubules, and Kinesin-6 at the cortex during cytokinesis in Drosophila S2 cells

    Vale, R. D., Spudich, J. A. & Griffis, E. R. 7 Sep 2009 In : Journal of Cell Biology. 186, 5, p. 727-738 12 p.

    Research output: Contribution to journalArticle

  295. ABC50 promotes translation initiation in mammalian cells

    Paytubi, S., Wang, X., Lam, Y. W., Izquierdo, L., Hunter, M. J., Jan, E., Hundal, H. S. & Proud, C. G. 4 Sep 2009 In : Journal of Biological Chemistry. 284, 36, p. 24061-24073 13 p.

    Research output: Contribution to journalArticle

  296. Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1

    Ahel, D., Horejsi, Z., Wiechens, N., Polo, S. E., Garcia-Wilson, E., Ahel, I., Flynn, H., Skehel, M., West, S. C., Jackson, S. P., Owen-Hughes, T. & Boulton, S. J. 4 Sep 2009 In : Science. 325, 5945, p. 1240-1243 4 p.

    Research output: Contribution to journalArticle

  297. Elongator function depends on antagonistic regulation by casein kinase Hrr25 and protein phosphatase Sit4

    Mehlgarten, C., Jablonowski, D., Breunig, K. D., Stark, M. J. R. & Schaffrath, R. Sep 2009 In : Molecular Microbiology. 73, 5, p. 869-881 13 p.

    Research output: Contribution to journalArticle

  298. Human miRNA Precursors with Box H/ACA snoRNA Features

    Scott, M. S., Avolio, F., Ono, M., Lamond, A. I. & Barton, G. J. Sep 2009 In : PLoS Computational Biology. 5, 9, p. - 13 p.e1000507

    Research output: Contribution to journalArticle

  299. The NM23 family in development

    Bilitou, A., Watson, J., Gartner, A. & Ohnuma, S. Sep 2009 In : Molecular and Cellular Biochemistry. 329, 1-2, p. 17-33 17 p.

    Research output: Contribution to journalArticle

  300. Structured-illumination microscopy of living cells

    Gustafsson, M. G. L., Kner, P., Chhun, B. B. & Griffis, E. R. 16 Aug 2009 In : Abstracts of Papers of the American Chemical Society. 238, p. - 1 p.

    Research output: Contribution to journalBook/Film/Article review

  301. Efficient chromosome biorientation and the tension checkpoint in saccharomyces cerevisiae both require Bir1

    Makrantoni, V. & Stark, M. J. R. 15 Aug 2009 In : Molecular and Cellular Biology. 29, 16, p. 4552-4562 11 p.

    Research output: Contribution to journalArticle

  302. The licensing checkpoint opens up

    Ge, X. Q. & Blow, J. J. 1 Aug 2009 In : Cell Cycle. 8, 15, p. 2320-2322 3 p.

    Research output: Contribution to journalComment/debate

  303. An additional role for SUMO in ubiquitin-mediated proteolysis

    Geoffroy, M-C. & Hay, R. T. Aug 2009 In : Nature Reviews Molecular Cell Biology. 10, 8, p. 564-568 5 p.

    Research output: Contribution to journalScientific review

  304. Neurogenesis, mitosis and centrosome: the role of DYRK1A

    Ferrandl, A. I., Storey, K. G. & Swedlow, J. R. Aug 2009 In : Mechanisms of Development. 126, Supplement, p. S128-S128 1 p.06-P028

    Research output: Contribution to journalBook/Film/Article review

  305. Quantitative Analysis of Proteome Localisation and Dynamics

    Lamond, A. Aug 2009 In : Molecular & Cellular Proteomics. 8, 8; suppl. 1, p. S26-S26 1 p.3.1

    Research output: Contribution to journalBook/Film/Article review

  306. SWI/SNF and Asf1p cooperate to displace histones during induction of the saccharomyces cerevisiae HO promoter

    Gkikopoulos, T., Havas, K. M., Dewar, H. & Owen-Hughes, T. Aug 2009 In : Molecular and Cellular Biology. 29, 15, p. 4057-4066 10 p.

    Research output: Contribution to journalArticle

  307. The developmental mutant talpid(3) lacks primary cilia

    Bangs, F., Yin, Y., Paton, R., Prescott, A., James, J., Davey, M., Whitley, P., Genikhovich, G., Technau, U., Briscoe, J., Burt, D. & Tickle, C. Aug 2009 In : Mechanisms of Development. 126, p. S262-S262 1 p.

    Research output: Contribution to journalBook/Film/Article review

  308. Characterization of SENP7, a SUMO-2/3-specific isopeptidase

    Shen, L. N., Geoffroy, M-C., Jaffray, E. G. & Hay, R. T. 15 Jul 2009 In : Biochemical Journal. 421, p. 223-230 8 p.

    Research output: Contribution to journalArticle

  309. Phosphorylation of the Tumor Suppressor Fat Is Regulated by Its Ligand Dachsous and the Kinase Discs Overgrown

    Sopko, R., Silva, E., Clayton, L., Gardano, L., Barrios-Rodiles, M., Wrana, J., Varelas, X., Arbouzova, N. I., Shaw, S., Saburi, S., Matakatsu, H., Blair, S. & McNeill, H. 14 Jul 2009 In : Current Biology. 19, 13, p. 1112-1117 6 p.

    Research output: Contribution to journalArticle

  310. PolySUMO chains target proteins for degradation

    Geoffroy, M. -C., Tatham, M. H., Shen, L., Plechanovova, A., Hattersley, N., Jaffray, E. G. & Hay, R. T. Jul 2009 In : Journal of Neurochemistry. 110, p. 32-32 1 p.

    Research output: Contribution to journalBook/Film/Article review

  311. The open microscopy environment: informatics and quantitative analysis for biological microscopy

    Swedlow, J. R., Allan, C., Burel, J-M., Linkert, M., Loranger, B., MacDonald, D., Moore, W. J., Patterson, A. J., Rueden, C., Tarkowska, A., Goldberg, I. G. & Eliceiri, K. W. Jul 2009 In : Microscopy and Microanalysis. 15, p. 1520-1521 2 p.

    Research output: Contribution to journalArticle

  312. Building a scientific data grid with DIGS

    Beckett, M. G., Allton, C. R., Davies, C. T. H., Davis, I., Flynn, J. M., Grant, E. J., Hamilton, R. S., Irving, A. C., Kenway, R. D., Ostrowski, R. H., Perry, J. T., Swedlow, J. R. & Trew, A. 28 Jun 2009 In : Philosophical Transactions of the Royal Society A - Mathematical Physical and Engineering Sciences. 367, 1897, p. 2471-2481 11 p.

    Research output: Contribution to journalArticle

  313. Phosphorylation of histone H3 Thr-45 is linked to apoptosis

    Hurd, P. J., Bannister, A. J., Halls, K., Dawson, M. A., Vermeulen, M., Olsen, J. V., Ismail, H., Somers, J., Mann, M., Owen-Hughes, T., Gout, I. & Kouzarides, T. 12 Jun 2009 In : Journal of Biological Chemistry. 284, 24, p. 16575-16583 9 p.

    Research output: Contribution to journalArticle

  314. System-wide changes to SUMO modifications in response to heat shock

    Golebiowski, F., Matic, I., Tatham, M. H., Cole, C., Yin, Y., Nakamura, A., Cox, J., Barton, G. J., Mann, M. & Hay, R. T. 26 May 2009 In : Science Signaling. 2, 72, 12 p.ra24

    Research output: Contribution to journalArticle

  315. Mutations to the histone H3 alpha N region selectively alter the outcome of ATP-dependent nucleosome-remodelling reactions

    Somers, J. & Owen-Hughes, T. May 2009 In : Nucleic Acids Research. 37, 8, p. 2504-2513 10 p.

    Research output: Contribution to journalArticle

  316. Super-resolution video microscopy of live cells by structured illumination

    Kner, P., Chhun, B. B., Griffis, E. R., Winoto, L. & Gustafsson, M. G. L. May 2009 In : Nature Methods. 6, 5, p. 339-342 4 p.

    Research output: Contribution to journalArticle

  317. FACT facilitates chromatin transcription by RNA polymerases I and III

    Birch, J. L., Tan, B. C-M., Panov, K. I., Panova, T. B., Andersen, J. S., Owen-Hughes, T. A., Russell, J., Lee, S-C. & Zomerdijk, J. C. B. M. 8 Apr 2009 In : EMBO Journal. 28, 7, p. 854-865 12 p.

    Research output: Contribution to journalArticle

  318. A model for DNA replication showing how dormant origins safeguard against replication fork failure

    Blow, J. J. & Ge, X. Q. Apr 2009 In : EMBO Reports. 10, 4, p. 406-412 7 p.

    Research output: Contribution to journalArticle

  319. Functional dissection of Caenorhabditis elegans CLK-2/TEL2 cell cycle defects during embryogenesis and germline development

    Moser, S. C., von Elsner, S., Buessing, I., Alpi, A., Schnabel, R. & Gartner, A. Apr 2009 In : PLoS Genetics. 5, 4, p. - 15 p.e1000451

    Research output: Contribution to journalArticle

  320. Glycosylation Directs Targeting and Activation of Cystatin F from Intracellular and Extracellular Sources

    Colbert, J. D., Plechanovova, A. & Watts, C. Apr 2009 In : Traffic. 10, 4, p. 425-437 13 p.

    Research output: Contribution to journalArticle

  321. The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation

    Yin, Y., Bangs, F., Paton, I. R., Prescott, A., James, J., Davey, M. G., Whitley, P., Genikhovich, G., Technau, U., Burt, D. W. & Tickle, C. 15 Feb 2009 In : Development. 136, 4, p. 655-664 10 p.

    Research output: Contribution to journalArticle

  322. SWI/SNF regulates the cellular response to hypoxia

    Kenneth, N. S., Mudie, S., van Uden, P. & Rocha, S. 13 Feb 2009 In : Journal of Biological Chemistry. 284, 7, p. 4123-4131 9 p.

    Research output: Contribution to journalArticle

  323. Long distance PELDOR measurements on the histone core particle

    Ward, R., Bowman, A., El-Mkami, H., Owen-Hughes, T. & Norman, D. G. 4 Feb 2009 In : Journal of the American Chemical Society. 131, 4, p. 1348-+ 3 p.

    Research output: Contribution to journalArticle

  324. Nucleosomes can invade DNA territories occupied by their neighbors

    Engeholm, M., de Jager, M., Flaus, A., Brenk, R., van Noort, J. & Owen-Hughes, T. Feb 2009 In : Nature Structural & Molecular Biology. 16, 2, p. 151-158 8 p.

    Research output: Contribution to journalArticle

  325. ABF1-binding sites promote efficient global genome nucleotide excision repair

    Yu, S., Smirnova, J. B., Friedberg, E. C., Stillman, B., Akiyama, M., Owen-Hughes, T., Waters, R. & Reed, S. H. 9 Jan 2009 In : Journal of Biological Chemistry. 284, 2, p. 966-973 8 p.

    Research output: Contribution to journalArticle

  326. In vivo imaging of mammalian cells: cell engineering and viability

    Swedlow, J. R., Andrews, P. D. & Platani, M. 1 Jan 2009 In : Cold Spring Harbor Protocols. 4, 9

    Research output: Contribution to journalArticle

  327. In vivo imaging of mammalian cells: image acquisition and analysis

    Swedlow, J. R., Andrews, P. D. & Platani, M. 1 Jan 2009 In : Cold Spring Harbor Protocols. 4, 9

    Research output: Contribution to journalArticle

  328. Towards a project community approach to academic scientific software development

    Loynton, S., Sloan, D., Burel, J-M. & MacAulay, C. 1 Jan 2009 e-science 2009: proceedings of the 2009 5th IEEE International Conference on e-Science Workshops. Institute of Electrical and Electronics Engineers, p. 120-124 5 p.

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  329. NOPdb: Nucleolar proteome database - 2008 Update

    Ahmad, Y., Boisvert, F-M., Gregor, P., Cobley, A. & Lamond, A. I. Jan 2009 In : Nucleic Acids Research. 37, Suppl. 1, p. D181-D184 4 p.

    Research output: Contribution to journalArticle

  330. Bioimage informatics for experimental biology

    Swedlow, J. R., Goldberg, I. G., Eliceiri, K. W. & OME Consortium 2009 In : Annual Review of Biophysics. 38, p. 327-346 20 p.

    Research output: Contribution to journalScientific review

  331. Chromosome biorientation in yeast

    Stark, M. J. R. 2009

    Research output: Non-textual formWeb publication/site

  332. Detection of protein SUMOylation in vivo

    Tatham, M. H., Rodriguez, M. S., Xirodimas, D. P. & Hay, R. T. 2009 In : Nature Protocols. 4, 9, p. 1363-1371 9 p.

    Research output: Contribution to journalArticle

  333. FRET-based in vitro assays for the analysis of SUMO protease activities

    Tatham, M. H. & Hay, R. T. 2009 SUMO protocols. Ulrich, H. D. (ed.). Humana Press, Vol. 6, p. 253-268 16 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  334. hExo70, a subunit of the exocyst complex -: a possible link between vesicular transport, pre-mRNA splicing and aging?

    Dellago, H., Grillari, J., Löscher , M., Ajuh, P., Ritter, G., Eisenhaber, F., Lamond, A. & Katinger, H. 2009 In : Experimental Gerontology. 44, 1-2, p. 128-128 1 p.

    Research output: Contribution to journalBook/Film/Article review

  335. Identification of nucleolar associated chromatin loci reveals clues for nuclear architecture

    van Koningsbruggen, S., Martin, D. M. A., Ariyurek, Y., den Dunnen, J. T. & Lamond, A. I. 2009 In : Cellular Oncology. 31, 2, p. 105-106 2 p.O16

    Research output: Contribution to journalBook/Film/Article review

  336. Kinetochore-microtubule interactions

    Clayton, L. & Tanaka, T. U. 2009 The kinetochore: from molecular discoveries to cancer therapy. De Wulf , P. & Earnshaw , W. C. (eds.). New York: Springer, p. 269-292 24 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  337. Live cell imaging of kinetochore capture by microtubules in budding yeast

    Tanaka, K. & Tanaka, T. U. 2009 Mitosis: methods and protocols. McAinsh, A. D. (ed.). Humana Press, p. 233-242 10 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  338. Live TIRF fluorescence imaging at 100nm resolution through structured illumination

    Kner, P., Chhun, B., Griffis, E., Winoto, L., Shao, L. & Gustafsson, M. G. L. 2009 Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XVI. Conchello, J. A., Cogswell, C. J. & Wilson, T. (eds.). Bellingham: SPIE-International Society for Optical Engineering, Vol. 7184, p. - 9 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  339. QUANTITATIVE ANALYSIS OF CHROMATIN HIGHER-ORDER ORGANIZATION IN LIVING CELLS

    Lieres, D., Visvanathan, A., James, J., Swift, S. & Lamond, A. I. 2009 In : Cellular Oncology. 31, 2, p. 121-121 1 p.P22

    Research output: Contribution to journalBook/Film/Article review

  340. Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing

    De Marco, V., Gillespie, P. J., Li, A., Karantzelis, N., Christodoulou, E., Klompmaker, R., van Gerwen, S., Fish, A., Petoukhov, M. V., Iliou, M. S., Lygerou, Z., Medema, R. H., Blow, J. J., Svergun, D. I., Taraviras, S. & Perrakis, A. 2009 In : Proceedings of the National Academy of Sciences of the United States of America. 106, 47, p. 19807-19812 6 p.

    Research output: Contribution to journalArticle

  341. Role of chromatin remodeling enzymes in the cellular response to hypoxia

    Melvin, A., Kenneth, N., Mudie, S. & Rocha, S. 2009 In : International Journal of Molecular Medicine. 24, p. S23-S23 1 p.

    Research output: Contribution to journalBook/Film/Article review

  342. TOPALi v2: a rich graphical interface for evolutionary analyses of multiple alignments on HPC clusters and multi-core desktops

    Milne, I., Lindner, D., Bayer, M., Husmeier, D., McGuire, G., Marshall, D. F. & Wright, F. 2009 In : Bioinformatics. 25, 1, p. 126-127 2 p.

    Research output: Contribution to journalArticle

  343. Usability and user-centered design in scientific software development

    Macaulay, C., Sloan, D., Jiang, X., Forbes, P., Loynton, S., Swedlow, J. R. & Gregor, P. 2009 In : IEEE Software. 26, 1, p. 96-102 7 p.

    Research output: Contribution to journalArticle

  344. User research in a scientific software development project

    Sloan, D., MacAulay, C., Forbes, P., Loynton, S. & Gregor, P. 2009 BCS-HCI '09: Proceedings of the 23rd British HCI Group Annual Conference on People and Computers: Celebrating People and Technology . Swindon: British Computer Society, p. 423-429 7 p.

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  345. MacroH2A allows ATP-dependent chromatin remodeling by SWI/SNF and ACF complexes but specifically reduces recruitment of SWI/SNF

    Chang, E. Y., Ferreira, H., Somers, J., Nusinow, D. A., Owen-Hughes, T. & Narlikar, G. J. 23 Dec 2008 In : Biochemistry. 47, 51, p. 13726-13732 7 p.

    Research output: Contribution to journalArticle

  346. Bi-orienting chromosomes: acrobatics on the mitotic spindle

    Tanaka, T. U. Dec 2008 In : Chromosoma. 117, 6, p. 521-533 13 p.

    Research output: Contribution to journalScientific review

  347. DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine

    Seifert, A., Allan, L. A. & Clarke, P. R. Dec 2008 In : FEBS Journal. 275, 24, p. 6268-6280 13 p.

    Research output: Contribution to journalArticle

  348. Structure of staphylococcus aureus EsxA suggests a contribution to virulence by action as a transport chaperone and/or adaptor protein

    Sundaramoorthy, R., Fyfe, P. K. & Hunter, W. N. 14 Nov 2008 In : Journal of Molecular Biology. 383, 3, p. 603-614 12 p.

    Research output: Contribution to journalArticle

  349. CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes

    Yip, M. F., Ramm, G., Larance, M., Hoehn, K. L., Wagner, M. C., Guilhaus, M. & James, D. E. 5 Nov 2008 In : Cell Metabolism. 8, 5, p. 384-398 15 p.

    Research output: Contribution to journalArticle

  350. Targeting a nucleolar SUMO protease for degradation: a mechanism by which ARF induces SUMO conjugation

    Xirodimas, D. P. & Lane, D. P. 1 Nov 2008 In : Cell Cycle. 7, 21, p. 3287-3288 2 p.

    Research output: Contribution to journalArticle

  351. The ubiquitin-proteasome system is a key component of the SUMO-2/3 cycle

    Schimmel, J., Larsen, K. M., Matic, I., van Hagen, M., Cox, J., Mann, M., Andersen, J. S. & Vertegaal, A. C. O. 1 Nov 2008 In : Molecular & Cellular Proteomics. 7, 11, p. 2107-2122 16 p.

    Research output: Contribution to journalArticle

  352. Splicing factors facilitate RNAi-directed silencing in fission yeast

    Bayne, E. H., Portoso, M., Kagansky, A., Kos-Braun, I. C., Urano, T., Ekwall, K., Alves, F., Rappsilber, J. & Allshire, R. C. 24 Oct 2008 In : Science. 322, 5901, p. 602-606 5 p.

    Research output: Contribution to journalArticle

  353. Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes

    Trinkle-Mulcahy, L., Boulon, S., Lam, Y. W., Urcia, R., Boisvert, F-M., Vandermoere, F., Morrice, N. A., Swift, S., Rothbauer, U., Leonhardt, H. & Lamond, A. 20 Oct 2008 In : Journal of Cell Biology. 183, 2, p. 223-239 17 p.

    Research output: Contribution to journalArticle

  354. C. elegans SIR-2.1 translocation is linked to a proapoptotic pathway parallel to cep-1/p53 during DNA damage-induced apoptosis

    Greiss, S., Hall, J., Ahmed, S. & Gartner, A. 15 Oct 2008 In : Genes & Development. 22, 20, p. 2831-2842 12 p.

    Research output: Contribution to journalArticle

  355. Novel substrates and functions for the ubiquitin-like molecule NEDD8

    Xirodimas, D. P. Oct 2008 In : Biochemical Society Transactions. 36, 5, p. 802-806 5 p.

    Research output: Contribution to journalArticle

  356. Replication licensing and cancer -: a fatal entanglement?

    Blow, J. J. & Gillespie, P. J. Oct 2008 In : Nature Reviews Cancer. 8, 10, p. 799-806 8 p.

    Research output: Contribution to journalScientific review

  357. Reversible Accumulation of PEGylated Single-Walled Carbon Nanotubes in the Mammalian Nucleus

    Cheng, J., Fernando, K. A. S., Veca, L. M., Sun, Y-P., Lamond, A. I., Lam, Y. W. & Cheng, S. H. Oct 2008 In : ACS Nano. 2, 10, p. 2085-2094 10 p.

    Research output: Contribution to journalArticle

  358. Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo

    Miles, W. O., Jaffray, E., Campbell, S. G., Takeda, S., Bayston, L. J., Basu, S. P., Li, M., Raftery, L. A., Ashe, M. P., Hay, R. T. & Ashe, H. L. 15 Sep 2008 In : Genes & Development. 22, 18, p. 2578-2590 13 p.

    Research output: Contribution to journalArticle

  359. Regulation of cyclin D1 RNA stability by SNIP1

    Bracken, C. P., Wall, S. J., Barré, B., Panov, K. I., Ajuh, P. M. & Perkins, N. D. 15 Sep 2008 In : Cancer Research. 68, 18, p. 7621-8 8 p.

    Research output: Contribution to journalArticle

  360. Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein

    Brummer, T., Larance, M., Herrera Abreu, M. T., Lyons, R. J., Timpson, P., Emmerich, C. H., Fleuren, E. D. G., Lehrbach, G. M., Schramek, D., Guilhaus, M., James, D. E. & Daly, R. J. 3 Sep 2008 In : EMBO Journal. 27, 17, p. 2305-2316 12 p.

    Research output: Contribution to journalArticle

  361. Cell cycle progression requires the CDC-48(UFD-1/NPL-4) complex for efficient DNA replication

    Mouysset, J., Deichsel, A., Moser, S., Hoege, C., Hyman, A. A., Gartner, A. & Hoppe, T. 2 Sep 2008 In : Proceedings of the National Academy of Sciences of the United States of America. 105, 35, p. 12879-12884 6 p.

    Research output: Contribution to journalArticle

  362. Using dialogical argument as an interface to complex debates

    Wells, S. & Reed, C. 1 Sep 2008 In : IEEE Potentials. 27, 5, p. 26-30 5 p.

    Research output: Contribution to journalArticle

  363. A versatile partner of eukaryotic protein complexes that is involved in multiple biological processes: Kti11/Dph3

    Baer, C., Zabel, R., Liu, S., Stark, M. J. R. & Schaffrath, R. Sep 2008 In : Molecular Microbiology. 69, 5, p. 1221-1233 13 p.

    Research output: Contribution to journalArticle

  364. ATP-dependent looping of DNA by ISWI

    Lia, G., Indrieri, M., Owen-Hughes, T., Finzi, L., Podesta, A., Milani, P. & Dunlap, D. Sep 2008 In : Journal of Biophotonics. 1, 4, p. 280-286 7 p.

    Research output: Contribution to journalArticle

  365. Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts

    Bru, T., Clarke, C., McGrew, M. J., Sang, H. M., Wilmut, I. & Blow, J. J. 15 Aug 2008 In : Experimental Cell Research. 314, 14, p. 2634-2642 9 p.

    Research output: Contribution to journalArticle

  366. Regulation of gene expression by hypoxia

    Kenneth, N. S. & Rocha, S. 15 Aug 2008 In : Biochemical Journal. 414, 1, p. 19-29 11 p.

    Research output: Contribution to journalScientific review

  367. Guidelines for reporting the use of gel electrophoresis in proteomics

    Gibson, F. , Anderson, L. , Babnigg, G. , Baker, M. , Berth, M. , Binz, P-A. , Borthwick, A. , Cash, P. , Day, B. W. , Friedman, D. B. , Garland, D. , Gutstein, H. B. , Hoogland, C. , Jones, N. A. , Khan, A. , Klose, J. , Lamond, A. I. , Lemkin, P. F. , Lilley, K. S. , Minden, J. & 10 others Morris, N. J., Paton, N. W., Pisano, M. R., Prime, J. E., Rabilloud, T., Stead, D. A., Taylor, C. F., Voshol, H., Wipat, A. & Jones, A. R. Aug 2008 In : Nature Biotechnology. 26, 8, p. 863-864 2 p.

    Research output: Contribution to journalLetter

  368. Regulation of the RelA (p65) transactivation domain

    O'Shea, J. M. & Perkins, N. D. Aug 2008 In : Biochemical Society Transactions. 36, Pt 4, p. 603-8 6 p.

    Research output: Contribution to journalArticle

  369. Structure and function of ribosomal RNA gene chromatin

    Birch, J. L. & Zomerdijk, J. C. B. M. Aug 2008 In : Biochemical Society Transactions. 36, p. 619-624 6 p.

    Research output: Contribution to journalArticle

  370. Transcriptional profiling in C-elegans suggests DNA damage dependent apoptosis as an ancient function of the p53 family

    Greiss, S., Schumacher, B., Grandien, K., Rothblatt, J. & Gartner, A. 15 Jul 2008 In : BMC Genomics. 9, p. - 10 p.334

    Research output: Contribution to journalArticle

  371. A population study of common truncating polymorphisms of profilaggrin and dry skin phenotype

    Sergeant, A., Campbell, L. E., Porter, M., Hull, P. R., Smith, F. J. D., McLean, W. H. I. & Munro, C. S. Jul 2008 In : British Journal of Dermatology. 159, p. 68-69 2 p.

    Research output: Contribution to journalBook/Film/Article review

  372. HIF-1alpha is a novel target of the SWI/SNF chromatin remodelling complex

    Rocha, S., Kenneth, N. S., van Uden, P. & Mudie, S. Jul 2008 In : EJC Supplements. 6, 9, p. 90-90 1 p.352

    Research output: Contribution to journalBook/Film/Article review

  373. Three-dimensional electron microscopy analysis of ndc10-1 mutant reveals an aberrant organization of the mitotic spindle and spindle pole body defects in Saccharomyces cerevisiae

    Romao, M., Tanaka, K., Sibarita, J-B., Ly-Hartig, N. T. B., Tanaka, T. U. & Antony, C. Jul 2008 In : Journal of Structural Biology. 163, 1, p. 18-28 11 p.

    Research output: Contribution to journalArticle

  374. Where in the cell is the minor spliceosome?

    Steitz, J. A., Dreyfuss, G., Krainer, A. R., Lamond, A. I., Matera, A. G. & Padgett, R. A. 24 Jun 2008 In : Proceedings of the National Academy of Sciences of the United States of America. 105, 25, p. 8485-8486 2 p.

    Research output: Contribution to journalEditorial

  375. Nuclear functions in space and time: Gene expression in a dynamic, constrained environment

    Trinkle-Mulcahy, L. & Lamond, A. I. 18 Jun 2008 In : FEBS Letters. 582, 14, p. 1960-1970 11 p.

    Research output: Contribution to journalScientific review

  376. Spatial mapping of splicing factor complexes involved in exon and intron definition

    Ellis, J. D., Lleres, D., Denegri, M., Lamond, A. I. & Caceres, J. F. 16 Jun 2008 In : Journal of Cell Biology. 181, 6, p. 921-934 14 p.

    Research output: Contribution to journalArticle

  377. Regulation of hypoxia-inducible factor-1 alpha by NF-kappa B

    van Uden, P., Kenneth, N. S. & Rocha, S. 15 Jun 2008 In : Biochemical Journal. 412, 3, p. 477-484 8 p.

    Research output: Contribution to journalArticle

  378. Temporal profiling of the chromatin proteome reveals system-wide responses to replication inhibition

    Khoudoli, G. A., Gillespie, P. J., Stewart, G., Andersen, J. S., Swedlow, J. R. & Blow, J. J. 3 Jun 2008 In : Current Biology. 18, 11, p. 838-843 6 p.

    Research output: Contribution to journalArticle

  379. Global view of nucleolar protein dynamics for P14ARF tumor suppressor signaling

    Yamada, K., Ono, M., Rocha, S., Perkins, N. & Lamond, A. Jun 2008 In : FEBS Journal. 275, Suppl. 1, p. 143-143 1 p.PP2B-36

    Research output: Contribution to journalBook/Film/Article review

  380. Protein dynamics in the cell nucleus

    Lamond, A., Boivert, F. M., Ono, M., Trinkle-Mulcahy, L., Koningsbruggen, S. V., Lleres, D., Andersen, J. & Mann, M. Jun 2008 In : FEBS Journal. 275, Suppl. 1, p. 8-8 1 p.IL 1C-5

    Research output: Contribution to journalBook/Film/Article review

  381. Targetes gene regulation mediated by nucleolar snoRNAs

    Ono, M., Scott, M., Yamada, K., Barton, G., Hutvagner, G. & Lamond, A. Jun 2008 In : FEBS Journal. 275, S1, p. 73-73 1 p.

    Research output: Contribution to journalBook/Film/Article review

  382. The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior

    Lee, H., Cho, J. S., Lambacher, N., Lee, J., Lee, S-J., Lee, T. H., Gartner, A. & Koo, H-S. 30 May 2008 In : Journal of Biological Chemistry. 283, 22, p. 14988-14993 6 p.

    Research output: Contribution to journalArticle

  383. Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

    Richard, D. J., Bolderson, E., Cubeddu, L., Wadsworth, R. I. M., Savage, K., Sharma, G. G., Nicolette, M. L., Tsvetanov, S., McIlwraith, M. J., Pandita, R. K., Takeda, S., Hay, R. T., Gautier, J., West, S. C., Paull, T. T., Pandita, T. K., White, M. F. & Khanna, K. K. 29 May 2008 In : Nature. 453, 7195, p. 677-U13 6 p.

    Research output: Contribution to journalArticle

  384. Discovery, in vivo activity and mechanism of action of a small-molecule p53 activator

    Lain, S., Hollick, J. J., Campbell, J., Staples, O. D., Higgins, M., Aoubala, M., McCarthy, A., Appleyard, V., Murray, K. E., Baker, L., Thompson, A., Mathers, J., Holland, S. J., Stark, M. J. R., Pass, G., Woods, J., Lane, D. P. & Westwood, N. J. 6 May 2008 In : Cancer Cell. 13, 5, p. 454-463 10 p.

    Research output: Contribution to journalArticle

  385. RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

    Tatham, M. H., Geoffroy, M-C., Shen, L., Plechanovova, A., Hattersley, N., Jaffray, E. G., Palvimo, J. J. & Hay, R. T. May 2008 In : Nature Cell Biology. 10, 5, p. 538-546 9 p.

    Research output: Contribution to journalArticle

  386. Correction: Human topoisomerase 2 alpha conjugates with SUMO-2 (vol 68, pg 2409, 2008)

    Agostinho, M., Santos, V., Ferreira, F., Costa, R., Cardoso, J., Pinheiro, I., Rino, J., Jaffray, E., Hay, R. T. & Ferreira, J. 15 Apr 2008 In : Cancer Research. 68, 8, p. 3076-3076 1 p.

    Research output: Contribution to journalArticle

  387. Conjugation of human topoisomerase 2 alpha with small ubiquitin-like modifiers 2/3 in response to topoisomerase inhibitors: cell cycle stage and chromosome domain specificity

    Agostinho, M., Santos, V., Ferreira, F., Costa, R., Cardoso, J., Pinheiro, I., Rino, J., Jaffray, E., Hay, R. T. & Ferreira, J. 1 Apr 2008 In : Cancer Research. 68, 7, p. 2409-2418 10 p.

    Research output: Contribution to journalArticle

  388. NF-kappa B is a critical regulator of the survival of rodent and human hepatic myofibroblasts

    Watson, M. R., Wallace, K., Gieling, R. G., Manas, D. M., Jaffray, E., Hay, R. T., Mann, D. A. & Oakley, F. Apr 2008 In : Journal of Hepatology. 48, 4, p. 589-597 9 p.

    Research output: Contribution to journalArticle

  389. Quantitative analysis of multi-protein interactions using FRET: application to the SUMO pathway

    Martin, S. F., Tatham, M. H., Hay, R. T. & Samuel, I. D. W. Apr 2008 In : Protein Science. 17, 4, p. 777-784 8 p.

    Research output: Contribution to journalArticle

  390. p53 activating benzoyl urea and benzoyl thiourea compounds

    Lain, S., Lane, D., Stark, M. J. R., McCarthy, A. R., Hollick, J. J. & Westwood, N. J. 13 Mar 2008 WO2008029096

    Research output: Patent

  391. Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE)

    Deutsch, E. W. , Ball, C. A. , Berman, J. J. , Bova, G. S. , Brazma, A. , Bumgarner, R. E. , Campbell, D. , Causton, H. C. , Christiansen, J. H. , Daian, F. , Dauga, D. , Davidson, D. R. , Gimenez, G. , Goo, Y. A. , Grimmond, S. , Henrich, T. , Herrmann, B. G. , Johnson, M. H. , Korb, M. , Mills, J. C. & 20 others Oudes, A. J., Parkinson, H. E., Pascal, L. E., Pollet, N., Quackenbush, J., Ramialison, M., Ringwald, M., Salgado, D., Sansone, S-A., Sherlock, G., Stoeckert, C. J., Swedlow, J., Taylor, R. C., Walashek, L., Warford, A., Wilkinson, D. G., Zhou, Y., Zon, L. I., Liu, A. Y. & True, L. D. Mar 2008 In : Nature Biotechnology. 26, 3, p. 305-312 8 p.

    Research output: Contribution to journalArticle

  392. Ribosomal proteins are targets for the NEDD8 pathway

    Xirodimas, D. P., Sundqvist, A., Nakamura, A., Shen, L., Botting, C. & Hay, R. T. Mar 2008 In : EMBO Reports. 9, 3, p. 280-286 7 p.

    Research output: Contribution to journalArticle

  393. The human intermediate filament database: Comprehensive information on a gene family involved in many human diseases

    Szeverenyi, I. , Cassidy, A. J. , Chung, C. W. , Lee, B. T. K. , Common, J. E. A. , Ogg, S. C. , Chen, H. , Sim, S. Y. , Goh, W. L. R. , Ng, K. W. , Simpson, J. A. , Chee, L. L. , Eng, G. H. , Li, B. , Lunny, D. P. , Chuon, D. , Venkatesh, A. , Khoo, K. H. , McLean, W. H. I. , Lim, Y. P. & 1 others Lane, E. B. Mar 2008 In : Human Mutation. 29, 3, p. 351-360 10 p.

    Research output: Contribution to journalArticle

  394. The GLUT4 code

    Larance, M., Ramm, G. & James, D. E. 1 Feb 2008 In : Molecular Endocrinology. 22, 2, p. 226-233 8 p.

    Research output: Contribution to journalArticle

  395. Kinetochore-microtubule interactions: the means to the end

    Tanaka, T. U. & Desai, A. Feb 2008 In : Current Opinion in Cell Biology. 20, 1, p. 53-63 11 p.

    Research output: Contribution to journalScientific review

  396. Displacement affinity chromatography of protein phosphatase one (PP1) complexes

    Moorhead, G. B. G., Trinkle-Mulcahy, L., Nimick, M., De Wever, V., Campbell, D. G., Gourlay, R., Lam, Y. W. & Lamond, A. I. 1 Jan 2008 In : BMC Biochemistry. 9, 1

    Research output: Contribution to journalArticle

  397. Germline survival and apoptosis

    Gartner, A., Boag, P. R. & Blackwell, T. K. 1 Jan 2008 In : WormBook. p. 1-20 20 p.

    Research output: Contribution to journalArticle

  398. In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy

    Matic, I., van Hagen, M., Schimmel, J., Macek, B., Ogg, S. C., Tatham, M. H., Hay, R. T., Lamond, A. I., Mann, M. & Vertegaal, A. C. O. 1 Jan 2008 In : Molecular & Cellular Proteomics. 7, 1, p. 132-144 13 p.

    Research output: Contribution to journalArticle

  399. Argonaute proteins: key players in RNA silencing

    Hutvagner, G. & Simard, M. J. Jan 2008 In : Nature Reviews Molecular Cell Biology. 9, 1, p. 22-32 11 p.

    Research output: Contribution to journalArticle

  400. Surface plasmon resonance imaging for real-time, label-free analysis of protein interactions with carbohydrate microarrays

    Karamanska, R., Clarke, J., Blixt, O., MacRae, J. I., Zhang, J. Q., Crocker, P. R., Laurent, N., Wright, A., Flitsch, S. L., Russell, D. A. & Field, R. A. Jan 2008 In : Glycoconjugate Journal. 25, 1, p. 69-74 6 p.

    Research output: Contribution to journalArticle

  401. AIF: Dialogue in the argument interchange format

    Reed, C., Wells, S., Devereux, J. & Rowe, G. 2008 Computational Models of Argument. Amsterdam: IOS Press, Vol. 172, p. 311-323 13 p. (Frontiers in Artifical Intelligence and Applications; 172).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  402. AIF(+): dialogue in the argument interchange format

    Reed, C., Wells, S., Devereux, J. & Rowe, G. 2008 COMPUTATIONAL MODELS OF ARGUMENT, PROCEEDINGS OF COMMA 2008. Besnard, P., Doutre, S. & Hunter, A. (eds.). AMSTERDAM: IOS Press, p. 311-323 13 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  403. Dual-specificity phosphatases in the hypo-osmotic stress response of keratin-defective epithelial cell lines

    Liovic, M., Lee, B., Tomic-Canic, M., D'Alessandro, M., Bolshakov, V. N. & Lane, E. B. 2008 In : Experimental Cell Research. 314, 10, p. 2066-2075 10 p.

    Research output: Contribution to journalArticle

  404. MAgtALO: an agent-based system for persuasive online interaction

    Wells, S. & Reed, C. 2008 AISB 2008 Convention Communication, Interaction and Social Intelligence: Volume 3: Proceedings of the AISB 2008 Symposium on Persuasive Technology. Society for the Study of Artificial Intelligence and Simulation of Behaviour, Vol. 3, p. 29-32 4 p.

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  405. Open tools for storage and management of quantitative image data

    Moore, J., Allan, C., Burel, J-M., Loranger, B., MacDonald, D., Monk, J. & Swedlow, J. R. 2008 Fluorescent Proteins. 2nd ed. San Diego: Academic Press, Vol. 85, p. 555-+ 20 p. (Methods in Cell Biology).

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  406. PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage

    Goehler, T., Munoz, I. M., Rouse, J. & Blow, J. J. 2008 In : DNA Repair. 7, 5, p. 775-787 13 p.

    Research output: Contribution to journalArticle

  407. Replication forks, chromatin loops and dormant replication origins

    Blow, J. J. & Ge, X. Q. 2008 In : Genome Biology. 9, 12, p. - 4 p.244

    Research output: Contribution to journalScientific review

  408. Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism

    Maure, J-F., Kitamura, E. & Tanaka, T. U. 18 Dec 2007 In : Current Biology. 17, 24, p. 2175-2182 8 p.

    Research output: Contribution to journalArticle

  409. Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress

    Ge, X. Q., Jackson, D. A. & Blow, J. J. 15 Dec 2007 In : Genes & Development. 21, 24, p. 3331-3341 11 p.

    Research output: Contribution to journalArticle

  410. Kinetochore-microtubule interaction during S phase in Saccharomyces cerevisiae

    Kitamura, E., Tanaka, K., Kitamura, Y. & Tanaka, T. U. 15 Dec 2007 In : Genes & Development. 21, 24, p. 3319-3330 12 p.

    Research output: Contribution to journalArticle

  411. A novel role for the yeast protein kinase Dbf2p in vacuolar H+-ATPase function and sorbic acid stress tolerance

    Makrantoni, V., Dennison, P., Stark, M. J. R. & Coote, P. J. Dec 2007 In : Microbiology-SGM. 153, p. 4016-4026 11 p.

    Research output: Contribution to journalArticle

  412. Caenorhabditis elegans prom-1 is required for meiotic prophase progression and homologous chromosome pairing

    Jantsch, V., Tang, L., Pasierbek, P., Penkner, A., Nayak, S., Baudrimont, A., Schedl, T., Gartner, A. & Loidl, J. Dec 2007 In : Molecular Biology of the Cell. 18, 12, p. 4911-4920 10 p.

    Research output: Contribution to journalArticle

  413. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator

    Lain, S., Hollick, J., Campbell, J., Staples, O. D., Higgins, M., Aoubala, M., McCarthy, A., Appleyard, V., Murray, K., Thompson, A., Mathers, J., Holland, S., Stark, M. J. R., Lane, D. & Westwood, N. J. Dec 2007 In : Molecular Cancer Therapeutics. 6, 12, p. 3476S-3477S 2 p.

    Research output: Contribution to journalBook/Film/Article review

  414. Evaluating performance in three-dimensional fluorescence microscopy

    Murray, J. M., Appleton, P. L., Swedlow, J. R. & Waters, J. C. Dec 2007 In : Journal of Microscopy. 228, 3, p. 390-405 16 p.

    Research output: Contribution to journalArticle

  415. Histone modifications influence the action of Snf2 family remodelling enzymes by different mechanisms

    Ferreira, H., Flaus, A. & Owen-Hughes, T. 30 Nov 2007 In : Journal of Molecular Biology. 374, 3, p. 563-579 17 p.

    Research output: Contribution to journalArticle

  416. Bod1, a novel kinetochore protein required for chromosome biorientation

    Porter, I. M., McClelland, S. E., Khoudoli, G. A., Hunter, C. J., Andersen, J. S., McAinsh, A. D., Blow, J. J. & Swedlow, J. R. 15 Oct 2007 In : Journal of Cell Biology. 179, 2, p. 187-197 11 p.

    Research output: Contribution to journalArticle

  417. ELYS/MEL-28 chromatin association coordinates nuclear pore complex assembly and replication licensing

    Gillespie, P. J., Khoudoli, G. A., Stewart, G., Swedlow, J. R. & Blow, J. J. 9 Oct 2007 In : Current Biology. 17, 19, p. 1657-62 6 p.

    Research output: Contribution to journalArticle

  418. Detecting protein-protein interactions in vivo with FRET using multiphoton fluorescence lifetime imaging microscopy (FLIM)

    Llères, D., Swift, S. & Lamond, A. I. Oct 2007 John Wiley & Sons

    Research output: Other contribution

  419. SUMO modification of the DEAD box protein p68 modulates its transcriptional activity and promotes its interaction with HDAC1

    Jacobs, A-M., Nicol, S. M., Hislop, R. G., Jaffray, E. G., Hay, R. T. & Fuller-Pace, F. V. 30 Aug 2007 In : Oncogene. 26, 40, p. 5866-76 11 p.

    Research output: Contribution to journalArticle

  420. Gene regulation under low oxygen: holding your breath for transcription

    Rocha, S. Aug 2007 In : Trends in Biochemical Sciences. 32, 8, p. 389-97 9 p.

    Research output: Contribution to journalArticle

  421. SUMO-specific proteases: a twist in the tail

    Hay, R. T. Aug 2007 In : Trends in Cell Biology. 17, 8, p. 370-6 7 p.

    Research output: Contribution to journalArticle

  422. Regulation of ATR-dependent pathways by the FHA domain containing protein SNIP1

    Roche, K. C., Rocha, S., Bracken, C. P. & Perkins, N. D. 5 Jul 2007 In : Oncogene. 26, 31, p. 4523-30 8 p.

    Research output: Contribution to journalArticle

  423. Blom7 - a novel splicing factor involved in cellular aging

    Schosserer, M., Lee, K., Löscher , M., Ajuh, P., Denegri, M., Lamond, A. I., Katinger, H., Voglauer, R. & Grillari, J. Jul 2007 In : FEBS Journal. 274, p. 361-361 1 p.C4-93

    Research output: Contribution to journalBook/Film/Article review

  424. Pyrosequencing positions nucleosomes precisely

    Owen-Hughes, T. & Engeholm, M. 27 Jun 2007 In : Genome Biology. 8, 6, p. 217

    Research output: Contribution to journalArticle

  425. Mitotic spindle orientation distinguishes stem cell and terminal modes of neuron production in the early spinal cord

    Wilcock, A. C., Swedlow, J. R. & Storey, K. G. 15 May 2007 In : Development. 134, 10, p. 1943-54 12 p.

    Research output: Contribution to journalArticle

  426. Analysis of Nucleolar Protein Dynamics Reveals the Nuclear Degradation of Ribosomal Proteins

    Lam, Y. W., Lamond, A. I., Mann, M. & Andersen, J. S. May 2007 In : Current Biology. 17, 9, p. 749-760 12 p.

    Research output: Contribution to journalArticle

  427. A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription

    Gorski, J. J., Pathak, S., Panov, K., Kasciukovic, T., Panova, T., Russell, J. & Zomerdijk, J. C. B. M. Mar 2007 In : The EMBO Journal. 26, 6, p. 1560-1568 9 p.

    Research output: Contribution to journalArticle

  428. 'Open minded' cells: how cells can change fate

    Costa, S. & Shaw, P. Mar 2007 In : Trends in Cell Biology. 17, 3, p. 101-6 6 p.

    Research output: Contribution to journalArticle

  429. Screening and characterization of microbial inhibitors against eukaryotic protein phosphatases (PP1 and PP2A)

    Ong, S. M., Voo, L. Y. C., Lai, N. S., Stark, M. J. R. & Ho, C. C. Mar 2007 In : Journal of Applied Microbiology. 102, 3, p. 680-92 13 p.

    Research output: Contribution to journalArticle

  430. Yeast genetics and strain construction

    Stansfield, I. & Stark, M. J. R. 1 Jan 2007 Methods in microbiology: yeast gene analysis. Stansfield, I. & Stark, M. J. R. (eds.). 2 ed. Netherlands: Academic Press, Vol. 36, p. 23-43 21 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  431. Integrating cell-signalling pathways with NF-κB and IKK function

    Perkins, N. D. Jan 2007 In : Nature Reviews Molecular Cell Biology. 8, 1, p. 49-62 14 p.

    Research output: Contribution to journalArticle

  432. A cell cycle regulatory network controlling NF-B subunit activity and function

    Barre, B. & Perkins, N. 2007 In : The EMBO Journal. 26, 23, p. 4841-4855 15 p.

    Research output: Contribution to journalArticle

  433. Characterization of a new SUMO-1 nuclear body (SNB) enriched in pCREB, CBP, c-Jun in neuron-like UR61 cells

    Navascues, J., Bengoechea, R., Tapia, O., Vaqué, J. P., Lafarga, M. & Berciano, M. T. 2007 In : Chromosoma. 116, 5, p. 441-451 11 p.

    Research output: Contribution to journalArticle

  434. Disease induced dynamics in host-parasitoid systems: chaos and coexistence

    Preedy, K. F., Schofield, P. G., Chaplain, M. A. J. & Hubbard, S. F. 2007 In : Journal of the Royal Society Interface. 4, 14, p. 463-471 9 p.

    Research output: Contribution to journalArticle

  435. FRG1P-mediated aggregation of proteins involved in pre-mRNA processing

    van Koningsbruggen, S., Straasheijm, K. R., Sterrenburg, E., de Graaf, N., Dauwerse, H. G., Frants, R. R. & van der Maarel, S. M. 2007 In : Chromosoma. 116, 1, p. 53-64 12 p.

    Research output: Contribution to journalArticle

  436. Histone tails and the H3 alphaN helix regulate nucleosome mobility and stability

    Ferreira, H., Somers, J., Webster, R., Flaus, A. & Owen-Hughes, T. 2007 In : Molecular and Cellular Biology. 27, 11, p. 4037-48 12 p.

    Research output: Contribution to journalArticle

  437. Ipl1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores

    King, E., Rachidi, N., Morrice, N., Hardwick, K. G. & Stark, M. J. R. 2007 In : Genes & Development. 21, 10, p. 1163-1168 6 p.

    Research output: Contribution to journalArticle

  438. Molecular mechanisms of microtubule-dependent kinetochore transport toward spindle poles

    Tanaka, K., Kitamura, E., Kitamura, Y. & Tanaka, T. U. 2007 In : Journal of Cell Biology. 178, 2, p. 269-81 13 p.

    Research output: Contribution to journalArticle

  439. Proenkephalin assists stress-activated apoptosis through transcriptional repression of NF-B- and p53-regulated gene targets

    McTavish, N., Copeland, L. A., Saville, M. K., Perkins, N. D. & Spruce, B. A. 2007 In : Cell Death & Differentiation. 14, 9, p. 1700-1710 11 p.

    Research output: Contribution to journalArticle

  440. Proteins interacting with Saccharomyces cerevisiae type 1 protein phosphatase catalytic subunit identified by single-step affinity purification and mass spectrometry

    Walsh, E. P., Lamont, D., Beattie, K. A. & Stark, M. J. R. 2007 Protein phosphatase protocols. Moorhead, G. (ed.). Humana Press, p. 235-246 12 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  441. Quantitative fluorescence microscopy and image deconvolution

    Swedlow, J. R. 2007 In : Methods in Cell Biology. 81, p. 447-65 19 p.

    Research output: Contribution to journalArticle

  442. Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases

    Fox, G. C., Shafiq, M., Briggs, D. C., Knowles, P. P., Collister, M., Didmon, M. J., Makrantoni, V., Dickinson, R. J., Hanrahan, S., Totty, N., Stark, M. J. R., Keyse, S. M. & McDonald, N. Q. 2007 In : Nature. 447, 7143, p. 487-492 6 p.

    Research output: Contribution to journalArticle

  443. Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore

    Griffis, E. R., Stuurman, N. & Vale, R. D. 2007 In : Journal of Cell Biology. 177, 6, p. 1005-15 11 p.

    Research output: Contribution to journalArticle

  444. Studying essential genes: generating and using promoter fusions and conditional alleles

    Stark, M. J. R. 2007 Yeast gene analysis . Stansfield, I. & Stark, M. J. R. (eds.). 2nd ed. San Diego: Academic Press, Vol. 36, p. 79-102 24 p. (Methods in Microbiology).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  445. The complement of protein kinases of the microsporidium Encephalitozoon cuniculi in relation to those of Saccharomyces cerevisiae and Schizosaccharomyces pombe

    Miranda-Saavedra, D., Stark, M. J. R., Packer, J. C., Vivares, C. P., Doerig, C. & Barton, G. J. 2007 In : BMC Genomics. 8, 309

    Research output: Contribution to journalArticle

  446. The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2

    Stevenson, L. F., Sparks, A., Allende-Vega, N., Xirodimas, D. P., Lane, D. & Saville, M. K. 2007 In : The EMBO Journal. 26, 4, p. 976-986 11 p.

    Research output: Contribution to journalArticle

  447. The elusive determinants of replication origins

    Costa, S. & Blow, J. J. 2007 In : EMBO Reports. 8, 4, p. 332-4 3 p.

    Research output: Contribution to journalArticle

  448. The multifunctional nucleolus

    Boisvert, F-M., van Koningsbruggen, S., Navascués, J. & Lamond, A. I. 2007 In : Nature Reviews Molecular Cell Biology. 8, 7, p. 574-585 12 p.

    Research output: Contribution to journalArticle

  449. The STAT3 oncogene as a predictive marker of drug resistance

    Barré, B., Vigneron, A., Perkins, N., Roninson, I. B., Gamelin, E. & Coqueret, O. 2007 In : Trends in Molecular Medicine. 13, 1, p. 4-11 8 p.

    Research output: Contribution to journalArticle

  450. The tagged microarray marker (TAM) method for high-throughput detection of single nucleotide and indel polymorphisms

    Jing, R., Bolshakov, V. & Flavell, A. J. 2007 In : Nature Protocols. 2, 1, p. 168-177 10 p.

    Research output: Contribution to journalArticle

  451. Toward a high-resolution view of nuclear dynamics

    Trinkle-Mulcahy, L. & Lamond, A. I. 2007 In : Science. 318, 5855, p. 1402-1407 6 p.

    Research output: Contribution to journalArticle

  452. Transcriptional profiling of the LPS induced NF-kappaB response in macrophages

    Sharif, O., Bolshakov, V. N., Raines, S., Newham, P. & Perkins, N. D. 2007 In : BMC Immunology. 8, p. 1

    Research output: Contribution to journalArticle

  453. Yeast gene analysis: the remaining challenges

    Stark, M. J. R. & Stansfield, I. 2007 Yeast gene analysis . 2 ed. San Diego: Academic Press, Vol. 36, p. 667-683 17 p. (Methods in Microbiology).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  454. SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes

    Fujii, M., Lyakh, L. A., Bracken, C. P., Fukuoka, J., Hayakawa, M., Tsukiyama, T., Soll, S. J., Harris, M., Rocha, S., Roche, K. C., Tominaga, S., Jen, J., Perkins, N. D., Lechleider, R. J. & Roberts, A. B. 8 Dec 2006 In : Molecular Cell. 24, 5, p. 771-83 13 p.

    Research output: Contribution to journalArticle

  455. SUMO protease SENP1 induces isomerization of the scissile peptide bond

    Shen, L., Tatham, M. H., Dong, C., Zagorska, A., Naismith, J. H. & Hay, R. T. Dec 2006 In : Nature Structural & Molecular Biology. 13, 12, p. 1069-1077 9 p.

    Research output: Contribution to journalArticle

  456. Identification of novel inhibitors of UDP-Glc 4 '-epimerase, a validated drug target for African sleeping sickness

    Urbaniak, M. D., Tabudravu, J. N., Msaki, A., Matera, K. M., Brenk, R., Jaspars, M. & Ferguson, M. A. J. 15 Nov 2006 In : Bioorganic & Medicinal Chemistry Letters. 16, 22, p. 5744-5747 4 p.

    Research output: Contribution to journalArticle

  457. UV-induced fragmentation of Cajal bodies

    Cioce, M., Boulon, S., Matera, A. G. & Lamond, A. I. 6 Nov 2006 In : Journal of Cell Biology. 175, 3, p. 401-413 13 p.

    Research output: Contribution to journalArticle

  458. Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision

    Davidson, I. F., Li, A. & Blow, J. J. Nov 2006 In : Molecular Cell. 24, 3, p. 433-443 11 p.

    Research output: Contribution to journalArticle

  459. Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit

    Schumm, K., Rocha, S., Caamano, J. & Perkins, N. D. Oct 2006 In : The EMBO Journal. 25, 20, p. 4820-4832 13 p.

    Research output: Contribution to journalArticle

  460. A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160

    Ramm, G., Larance, M., Guilhaus, M. & James, D. E. 29 Sep 2006 In : Journal of Biological Chemistry. 281, 39, p. 29174-29180 7 p.

    Research output: Contribution to journalArticle

  461. The DNA repair helicases XPD and FancJ have essential iron-sulfur domains

    Rudolf, J., Makrantoni, V., Ingledew, W. J., Stark, M. J. R. & White, M. F. 15 Sep 2006 In : Molecular Cell. 23, 6, p. 801-8 8 p.

    Research output: Contribution to journalArticle

  462. RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor

    Panov, K. I., Panova, T. B., Gadal, O., Nishiyama, K., Saito, T., Russell, J. & Zomerdijk, J. C. B. M. Jul 2006 In : Molecular and Cellular Biology. 26, 14, p. 5436-5448 13 p.

    Research output: Contribution to journalArticle

  463. The Saccharomyces cerevisiae orthologue of the human protein phosphatase 4 core regulatory subunit R2 confers resistance to the anticancer drug cisplatin

    Hastie, C. J., Vázquez-Martin, C., Philp, A., Stark, M. J. R. & Cohen, P. T. W. Jul 2006 In : FEBS Journal. 273, 14, p. 3322-34 13 p.

    Research output: Contribution to journalArticle

  464. Regulating the licensing of DNA replication origins in metazoa

    DePamphilis, M. L., Blow, J. J., Ghosh, S., Saha, T., Noguchi, K. & Vassilev, A. Jun 2006 In : Current Opinion in Cell Biology. 18, 3, p. 231-9 9 p.

    Research output: Contribution to journalArticle

  465. Mating-type locus control of killer toxins from Kluyveromyces lactis and Pichia acaciae

    Klassen, R., Jablonowski, D., Stark, M. J. R., Schaffrath, R. & Meinhardt, F. May 2006 In : FEMS Yeast Research. 6, 3, p. 404-13 10 p.

    Research output: Contribution to journalArticle

  466. The suppression of galactose metabolism in Trypanosoma cruzi epimastigotes causes changes in cell surface molecular architecture and cell morphology

    MacRae, J. I., Obado, S. O., Turnock, D. C., Roper, J. R., Kierans, M., Kelly, J. M. & Ferguson, M. A. J. May 2006 In : Molecular and Biochemical Parasitology. 147, 1, p. 126-136 11 p.

    Research output: Contribution to journalArticle

  467. Direct observation of DNA distortion by the RSC complex

    Lia, G., Praly, E., Ferreira, H., Stockdale, C., Tse-Dinh, Y. C., Dunlap, D., Croquette, V., Bensimon, D. & Owen-Hughes, T. Feb 2006 In : Molecular Cell. 21, 3, p. 417-425 9 p.

    Research output: Contribution to journalArticle

  468. Cisplatin mimics ARF tumor suppressor regulation of RelA (p65) nuclear factor-kappaB transactivation

    Campbell, K. J., Witty, J. M., Rocha, S. & Perkins, N. D. Jan 2006 In : Cancer Research. 66, 2, p. 929-935 7 p.

    Research output: Contribution to journalArticle

  469. Analysis of nucleosome repositioning by yeast ISWI and Chd1 chromatin remodeling complexes

    Stockdale, C., Flaus, A., Ferreira, H. & Owen-Hughes, T. 2006 In : Journal of Biological Chemistry. 281, 24, p. 16279-88 10 p.

    Research output: Contribution to journalArticle

  470. Casein kinase 2 associates with initiation-competent RNA polymerase I and has multiple roles in ribosomal DNA transcription

    Panova, T. B., Panov, K. I., Russell, J. & Zomerdijk, J. C. B. M. 2006 In : Molecular and Cellular Biology. 26, 16, p. 5957-5968 12 p.

    Research output: Contribution to journalArticle

  471. Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress

    Woodward, A. M., Göhler, T., Luciani, M. G., Oehlmann, M., Ge, X., Gartner, A., Jackson, D. A. & Blow, J. J. 2006 In : Journal of Cell Biology. 173, 5, p. 673-83 11 p.

    Research output: Contribution to journalArticle

  472. Knowing when to bargain: the role of negotiation and persuasion in dialogue

    Wells, S. & Reed, C. 2006 Computational models of argument. Dunne, P. E. & BenchCapon, T. J. M. (eds.). AMSTERDAM: Oxford University Press for The International Institute for Strategic Studies, p. 235-246 12 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  473. Live-cell imaging reveals replication of individual replicons in eukaryotic replication factories

    Kitamura, E., Blow, J. J. & Tanaka, T. U. 2006 In : Cell. 125, 7, p. 1297-1308 12 p.

    Research output: Contribution to journalArticle

  474. Modelling the spatio-temporal dynamics of multi-species host-parasitoid interactions: heterogeneous patterns and ecological implications

    Pearce, I. G., Chaplain, M. A. J., Schofield, P. G., Anderson, A. R. A. & Hubbard, S. F. 2006 In : Journal of Theoretical Biology. 241, 4, p. 876-886 11 p.

    Research output: Contribution to journalArticle

  475. Snf2 family ATPases and DExx box helicases: differences and unifying concepts from high-resolution crystal structures

    Dürr, H., Flaus, A., Owen-Hughes, T. & Hopfner, K-P. 2006 In : Nucleic Acids Research. 34, 15, p. 4160-7 8 p.

    Research output: Contribution to journalArticle

  476. The RNA polymerase I transcription machinery

    Russell, J. & Zomerdijk, J. C. B. M. 2006 Transcription: papers from the Biochemical Society symposium no. 73, held at Imperial College, London, April 2005. Roberts, S., Weinzierl, R. & White, R. (eds.). London: Portland Press Ltd, p. 203-216 14 p. (Biochemical Society symposia).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  477. UBF activates RNA polymerase I transcription by stimulating promoter escape

    Panov, K. I., Friedrich, J. K., Russell, J. & Zomerdijk, J. C. B. M. 2006 In : The EMBO Journal. 25, 14, p. 3310-3322 13 p.

    Research output: Contribution to journalArticle

  478. Global analysis of protein phosphorylation in yeast

    Stark, M. J. R. & 24 others Ptacek, J., Devgan, G., Michaud, G., Zhu, H., Zhu, X., Fasolo, J., Guo, H., Jona, G., Breitkreutz, A., Sopko, R., McCartney, R. R., Schmidt, M. C., Rachidi, N., Lee, S-J., Mah, A. S., Meng, L., Stern, D. F., De Virgilio, C., Tyers, M., Andrews, B., Gerstein, M., Schweitzer, B., Predki, P. F. & Snyder, M. 1 Dec 2005 In : Nature. 438, 7068, p. 679-684 6 p.

    Research output: Contribution to journalLetter

  479. Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking

    Larance, M., Ramm, G., Stöckli, J., van Dam, E. M., Winata, S., Wasinger, V., Simpson, F., Graham, M., Junutula, J. R., Guilhaus, M. & James, D. E. 11 Nov 2005 In : Journal of Biological Chemistry. 280, 45, p. 37803-37813 11 p.

    Research output: Contribution to journalArticle

  480. p53 isoforms can regulate p53 transcriptional activity

    Bourdon, J. C., Fernandes, K., Murray-Zmijewski, F., Liu, G., Diot, A., Xirodimas, D. P., Saville, M. K. & Lane, D. P. 15 Sep 2005 In : Genes & Development. 19, 18, p. 2122-2137 16 p.

    Research output: Contribution to journalArticle

  481. Two-dimensional liquid chromatography/tandem mass spectrometry analysis of Gradiflow fractionated native human plasma

    Wasinger, V. C., Locke, V. L., Raftery, M. J., Larance, M., Rothemund, D., Liew, A., Bate, I. & Guilhaus, M. Aug 2005 In : Proteomics. 5, 13, p. 3397-3401 5 p.

    Research output: Contribution to journalArticle

  482. ARF the integrator: linking NF-kappaB, p53 and checkpoint kinases

    Rocha, S. & Perkins, N. D. Jun 2005 In : Cell Cycle. 4, 6, p. 756-9 4 p.

    Research output: Contribution to journalArticle

  483. The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number

    Roper, J. R., Guther, M. L. S., MacRae, J. I., Prescott, A. R., Hallyburton, I., Acosta-Serrano, A. & Ferguson, M. A. J. 20 May 2005 In : Journal of Biological Chemistry. 280, 20, p. 19728-19736 9 p.

    Research output: Contribution to journalArticle

  484. Mannosyl-diinositolphospho-ceramide, the major yeast plasma membrane sphingolipid, governs toxicity of Kluyveromyces lactis zymocin

    Zink, S., Mehlgarten, C., Kitamoto, H. K., Nagase, J., Jablonowski, D., Dickson, R. C., Stark, M. J. R. & Schaffrath, R. May 2005 In : Eukaryotic Cell. 4, 5, p. 879-89 11 p.

    Research output: Contribution to journalArticle

  485. Structural characterization of NETNES, a novel glycoconjugate in Trypanosoma cruzi epimastigotes

    MacRae, J. I., Acosta-Serrano, A., Morrice, N. A., Mehlert, A. & Ferguson, M. A. J. 1 Apr 2005 In : Journal of Biological Chemistry. 280, 13, p. 12201-12211 11 p.

    Research output: Contribution to journalArticle

  486. Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1

    Shen, L., Liu, H., Dong, C., Xirodimas, D., Naismith, J. H. & Hay, R. T. Apr 2005 In : The EMBO Journal. 24, 7, p. 1341-1351 11 p.

    Research output: Contribution to journalArticle

  487. Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor

    Rocha, S., Garrett, M. D., Campbell, K. J., Schumm, K. & Perkins, N. D. Mar 2005 In : EMBO Journal. 24, 6, p. 1157-1169 13 p.

    Research output: Contribution to journalArticle

  488. The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor

    Bates, G. J., Nicol, S. M., Wilson, B. J., Jacobs, A-M. F., Bourdon, J-C., Wardrop, J., Gregory, D. J., Lane, D. P., Perkins, N. D. & Fuller-Pace, F. V. 9 Feb 2005 In : The EMBO Journal. 24, 3, p. 543-553 11 p.

    Research output: Contribution to journalArticle

  489. A robust and selective method for the quantification of glycosylphosphatidylinositols in biological samples

    MacRae, J. I. & Ferguson, M. A. J. Feb 2005 In : Glycobiology. 15, 2, p. 131-138 8 p.

    Research output: Contribution to journalArticle

  490. Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis

    Schumacher, B., Hanazawa, M., Lee, M-H., Nayak, S., Volkmann, K., Hofmann, R., Hengartner, M., Schedl, T. & Gartner, A. Feb 2005 In : Cell. 120, 3, p. 357-368 12 p.

    Research output: Contribution to journalArticle

  491. Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus

    Li, A. & Blow, J. J. Jan 2005 In : The EMBO Journal. 24, 2, p. 395-404 10 p.

    Research output: Contribution to journalArticle

  492. Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection

    Tatham, M. H., Kim, S., Jaffray, E., Song, J., Chen, Y. & Hay, R. T. Jan 2005 In : Nature Structural & Molecular Biology. 12, 1, p. 67-74 8 p.

    Research output: Contribution to journalArticle

  493. Chromosome bi-orientation on the mitotic spindle

    Tanaka, T. U. 2005 In : Philosophical Transactions of the Royal Society B - Biological Sciences. 360, 1455, p. 581-9 9 p.

    Research output: Contribution to journalArticle

  494. Evolution of searching and life history characteristics in individual-based models of host-parasitoid-microbe associations

    Schofield, P., Chaplain, M. & Hubbard, S. 2005 In : Journal of Theoretical Biology. 237, 1, p. 1-16 16 p.

    Research output: Contribution to journalArticle

  495. Functional domains of the Xenopus replication licensing factor Cdt1

    Ferenbach, A., Li, A., Brito-Martins, M. & Blow, J. J. 2005 In : Nucleic Acids Research. 33, 1, p. 316-24 9 p.

    Research output: Contribution to journalArticle

  496. Glutathione transferases

    Hayes, J. D., Flanagan, J. U. & Jowsey, I. R. 2005 In : Annual Review of Pharmacology and Toxicology. 45, p. 51-88 38 p.

    Research output: Contribution to journalArticle

  497. Kinetochore capture and bi-orientation on the mitotic spindle

    Tanaka, T. U., Stark, M. J. R. & Tanaka, K. 2005 In : Nature Reviews Molecular Cell Biology. 6, 12, p. 929-42 14 p.

    Research output: Contribution to journalArticle

  498. Molecular mechanisms of kinetochore capture by spindle microtubules

    Tanaka, K., Mukae, N., Dewar, H., Breugel, M. V., James, E. K., Prescott, A. R., Antony, C. & Tanaka, T. U. 2005 In : Nature. 434, 7036, p. 987-994 8 p.

    Research output: Contribution to journalArticle

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