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  1. Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

    Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J. 20 Nov 2016 New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January, p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  2. During postnatal development endogenous neurosteroids influence GABA-ergic neurotransmission of mouse cortical neurons

    Brown, A. R., Mitchell, S., Peden, D. R., Herd, M. B., Seifi, M., Swinny, J. D., Belelli, D. & Lambert, J. Apr 2016 In : Neuropharmacology. 103, p. 163-173 11 p.

    Research output: Contribution to journalArticle

  3. Association between allopurinol use and hip fracture in older patients

    Basu, U., Goodbrand, J., McMurdo, M. E. T., Donnan, P. T., McGilchrist, M., Frost, H., George, J. & Witham, M. D. Mar 2016 In : Bone. 84, p. 189-193 5 p.

    Research output: Contribution to journalArticle

  4. A spontaneous increase in intracellular Ca2+ in metaphase II human oocytes in vitro can be prevented by drugs targeting ATP-sensitive K+ channels

    Fernandes, G., Dasai, N., Kozlova, N., Mojadadi, A., Gall, M., Drew, E., Barratt, E., Madamidola, O. A., Brown, S. G., Milne, A. M., Martins Da Silva, S. J., Whalley, K. M., Barratt, C. L. R. & Jovanovic, A. Feb 2016 In : Human Reproduction. 31, 2, p. 287-297 11 p.

    Research output: Contribution to journalArticle

  5. Effect of atorvastatin on glycaemia progression in patients with diabetes: an analysis from the Collaborative Atorvastatin in Diabetes Trial (CARDS)

    Livingstone, S. J., Looker, H. C., Akbar, T., Betteridge, D. J., Durrington, P. N., Hitman, G. A., Neil, H. A. W., Fuller, J. H. & Colhoun, H. M. Feb 2016 In : Diabetologia. 59, 2, p. 299-306 8 p.

    Research output: Contribution to journalArticle

  6. Can angiotensin-converting enzyme inhibitors reduce the incidence, severity, and duration of radiation proctitis?

    Alashkham, A., Paterson, C., Rauchhaus, P. & Nabi, G. Jan 2016 In : International Journal of Radiation Oncology Biology Physics. 94, 1, p. 93-101 9 p.

    Research output: Contribution to journalArticle

  7. Clinical utility of one versus two faecal immunochemical test samples in the detection of advanced colorectal neoplasia in symptomatic patients

    Auge, J. M., Fraser, C. G., Rodriguez, C., Roset, A., Lopez-Ceron, M., Grau, J., Castells, A. & Jimenez, W. Jan 2016 In : Clinical Chemistry and Laboratory Medicine. 54, 1, p. 125-132 8 p.

    Research output: Contribution to journalArticle

  8. From mouse to man: Predicting biased effects of beta-blockers in asthma

    Lipworth, B. J., Anderson, W. J. & Short, P. M. Jan 2016 In : British Journal of Pharmacology. 173, 1, p. 248-249 2 p.

    Research output: Contribution to journalArticle

  9. Inhaled corticosteroid dose-response on blood eosinophils in asthma

    Lipworth, B., Jabbal, S., Manoharan, A., Anderson, W. & Short, P. Jan 2016 In : The Lancet Respiratory Medicine. 4, 1, p. e1

    Research output: Contribution to journalArticle

  10. Re: A proposal to standardize reporting units for fecal immunochemical tests for hemoglobin

    Fraser, C. G., Rapi, S. & Rubeca, T. Jan 2016 In : Journal of the National Cancer Institute. 108, 1, 2 p., djv312

    Research output: Contribution to journalLetter

  11. Effects of adding Tiotropium or Aclidinium as triple therapy using impulse oscillometry in COPD

    Manoharan, A., Morrison, A. E. & Lipworth, B. 2016 In : Lung. 8 p.

    Research output: Contribution to journalArticle

  12. Structured antibiotic 'time-out' audits as recommended by the CDC reduce antibiotic use and costs

    Davey, P. G. 2016 In : Evidence-Based Nursing. 19, 1, p. 24 1 p.

    Research output: Contribution to journalArticle

  13. DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions

    Huang, W. , Thomas, B. , Flynn, R. A. , Gavzy, S. J. , Wu, L. , Kim, S. V. , Hall, J. A. , Miraldi, E. R. , Ng, C. P. , Rigo, F. , Meadows, S. , Montoya, N. R. , Herrera, N. G. , Domingos, A. I. , Rastinejad, F. , Myers, R. M. , Fuller-Pace, F. V. , Bonneau, R. , Chang, H. Y. , Acuto, O. & 1 others Littman, D. R. 24 Dec 2015 In : Nature. 528, 7583, p. 517-522 6 p., 16193

    Research output: Contribution to journalArticle

  14. The copper binding properties of metformin - QCM-D, XPS and nanobead agglomeration

    Quan, X., Uddin, R., Heiskanen, A., Parmvi, M., Nilson, K., Donolato, M., Hansen, M. F., Rena, G. & Boisen, A. 18 Dec 2015 In : Chemical Communications. 51, 97, p. 17313-17316 4 p.

    Research output: Contribution to journalArticle

  15. Functional piezocrystal characterisation under varying conditions

    Liao, X., Qiu, Z., Jiang, T., Sadiq, M. R., Huang, Z., Demore, C. E. M. & Cochran, S. 2 Dec 2015 In : Materials. 8, 12, p. 8304-8326 23 p.

    Research output: Contribution to journalArticle

  16. Decision support for diabetes: implementation and evaluation of the EBMeDS project within NHS Scotland

    Conway, N., Cunningham, S., Forbes, P., Shaik, F., Emslie-Smith, A., Wales, A. & Wake, D. 1 Dec 2015

    Research output: Contribution to conferencePoster

  17. Health state utilities associated with attributes of treatments for hepatitis C

    Matza, L. S., Sapra, S. J., Dillon, J. F., Kalsekar, A., Davies, E. W., Devine, M. K., Jordan, J. B., Landrian, A. S. & Feeny, D. H. 1 Dec 2015 In : European Journal of Health Economics. 16, 9, p. 1005-1018 14 p.

    Research output: Contribution to journalArticle

  18. Clinical practice guidelines and the older patient: wake up call for geriatricians

    Vilches-Moraga, A., Martinez-Velilla, N., Cherubini, A., McMurdo, M., Singh, I. & Pattison, T. Dec 2015 In : European Geriatric Medicine. 6, 6, p. 513-514 2 p.

    Research output: Contribution to journalEditorial

  19. Etiology of non-cystic fibrosis bronchiectasis in adults and its correlation to disease severity

    Lonni, S., Chalmers, J. D., Goeminne, P. C., McDonnell, M. J., Dimakou, K., De Soyza, A., Polverino, E., Van De Kerkhove, C., Rutherford, R., Davison, J., Rosales, E., Pesci, A., Restrepo, M. I., Torres, A. & Aliberti, S. Dec 2015 In : Annals of the American Thoracic Society. 12, 12, p. 1764-1770 7 p.

    Research output: Contribution to journalArticle

  20. Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis

    Riethmuller, C., McAleer, M. A., Koppes, S. A., Abdayem, R., Franz, J., Haftek, M., Campbell, L. E., MacCallum, S. F., McLean, W. H. I., Irvine, A. D. & Kezic, S. Dec 2015 In : Journal of Allergy and Clinical Immunology. 136, 6, p. 1573-1580.e2 10 p.

    Research output: Contribution to journalArticle

  21. Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

    Morris, A. P. & 97 others Artigas, M. S., Wain, L. V., Miller, S., Kheirallah, A. K., Huffman, J. E., Ntalla, I., Shrine, N., Obeidat, M., Trochet, H., McArdle, W. L., Alves, A. C., Hui, J., Zhao, J. H., Joshi, P. K., Teumer, A., Albrecht, E., Imboden, M., Rawal, R., Lopez, L. M., Marten, J., Enroth, S., Surakka, I., Polasek, O., Lyytikäinen, L. P., Granell, R., Hysi, P. G., Flexeder, C., Mahajan, A., Beilby, J., Bossé, Y., Brandsma, C. A., Campbell, H., Gieger, C., Gläser, S., González, J. R., Grallert, H., Hammond, C. J., Harris, S. E., Hartikainen, A. L., Heliövaara, M., Henderson, J., Hocking, L., Horikoshi, M., Hutri-Kähönen, N., Ingelsson, E., Johansson, Å., Kemp, J. P., Kolcic, I., Kumar, A., Lind, L., Melén, E., Musk, A. W., Navarro, P., Nickle, D. C., Padmanabhan, S., Raitakari, O. T., Ried, J. S., Ripatti, S., Schulz, H., Scott, R. A., Sin, D. D., Starr, J. M., Viñuela, A., Völzke, H., Wild, S. H., Wright, A. F., Zemunik, T., Jarvis, D. L., Spector, T. D., Evans, D. M., Lehtimäki, T., Vitart, V., Kähönen, M., Gyllensten, U., Rudan, I., Deary, I. J., Karrasch, S., Probst-Hensch, N. M., Heinrich, J., Stubbe, B., Wilson, J. F., Wareham, N. J., James, A. L., Jarvelin, M. R., Hayward, C., Sayers, I., Strachan, D. P., Hall, I. P., Tobin, M. D., Deloukas, P., Hansell, A. L., Hubbard, R., Jackson, V. E., Marchini, J., Pavord, I., Thomson, N. C. & Zeggini, E. Dec 2015 In : Nature Communications. 6, 89658

    Research output: Contribution to journalArticle

  22. The Concise Guide to PHARMACOLOGY 2015/16: Nuclear hormone receptors

    Alexander, S. P., Cidlowski, J. A., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C. & Davies, J. A. Dec 2015 In : British Journal of Pharmacology. 172, 24, p. 5956-5978 23 p.

    Research output: Contribution to journalArticle

  23. The Concise Guide to PHARMACOLOGY 2015/16: Overview

    Alexander, S. P. H., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C., Buneman, O. P., Catterall, W. A., Cidlowski, J. A., Davenport, A. P., Fabbro, D., Fan, G., McGrath, J. C., Spedding, M. & Davies, J. A. Dec 2015 In : British Journal of Pharmacology. 172, 24, p. 5729-5743 15 p.

    Research output: Contribution to journalArticle

  24. The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors

    Alexander, S. P. H., Davenport, A. P., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C. & Davies, J. A. Dec 2015 In : British Journal of Pharmacology. 172, 24, p. 5744-5869 126 p.

    Research output: Contribution to journalArticle

  25. Towards an ICF core set for ADHD: a worldwide expert survey on ability and disability

    de Schipper, E., Mahdi, S., Coghill, D., de Vries, P. J., Gau, S. S. F., Granlund, M., Holtmann, M., Karande, S., Levy, F., Almodayfer, O., Rohde, L., Tannock, R. & Bölte, S. Dec 2015 In : European Child & Adolescent Psychiatry. 24, 12, p. 1509-1521 13 p.

    Research output: Contribution to journalArticle

  26. Implementation of the Lancet Standing Commission on liver disease in the UK

    Williams, R. , Ashton, K. , Aspinall, R. , Bellis, M. A. , Bosanquet, J. , Cramp, M. E. , Day, N. , Dhawan, A. , Dillon, J. , Dyson, J. , Ferguson, J. , Foster, G. , Gilmore, I. , Glynn, M. , Guthrie, J. A. , Hudson, M. , Kelly, D. , Langford, A. , Newsome, P. , O'Grady, J. & 5 others Pryke, R., Ryder, S., Samyn, M., Sheron, N. & Verne, J. 21 Nov 2015 In : Lancet. 386, 10008, p. 2098-2111 14 p.

    Research output: Contribution to journalArticle

  27. Risk of postoperative acute kidney injury in patients undergoing orthopaedic surgery—development and validation of a risk score and effect of acute kidney injury on survival: observational cohort study

    Bell, S., Dekker, F. W., Vadiveloo, T., Marwick, C., Deshmukh, H., Donnan, P. T. & Van Diepen, M. 11 Nov 2015 In : BMJ. 351, 9 p., h5639

    Research output: Contribution to journalArticle

  28. Activation status of the Pregnane X Receptor influences Vemurafenib availability in humanized mouse models

    MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R. 1 Nov 2015 In : Cancer Research. 75, 21, p. 4573-4581 10 p.

    Research output: Contribution to journalArticle

  29. Strategies for the treatment of Hepatitis C in an era of interferon-free therapies: what public health outcomes do we value most?

    Innes, H., Goldberg, D., Dillon, J. & Hutchinson, S. J. 1 Nov 2015 In : Gut. 64, 11, p. 1800-1809 10 p.

    Research output: Contribution to journalArticle

  30. Association between kidney function, rehabilitation outcome, and survival in older patients discharged from inpatient rehabilitation

    Doyle, E. M., Sloan, J. M., Goodbrand, J. A., McMurdo, M. E. T., Donnan, P. T., McGilchrist, M. M., Frost, H. & Witham, M. D. Nov 2015 In : American Journal of Kidney Diseases. 66, 5, p. 768-774 7 p.

    Research output: Contribution to journalArticle

  31. Association between retinal vasculature and muscle mass in older people

    Sumukadas, D., McMurdo, M., Pieretti, I., Ballerini, L., Price, R., Wilson, P., Doney, A., Leese, G. & Trucco, E. Nov 2015 In : Archives of Gerontology and Geriatrics. 61, 3, p. 425-428 4 p.

    Research output: Contribution to journalArticle

  32. Challenges and controversies in management of pancreatic neuroendocrine tumours in patients with MEN1

    Yates, C. J., Newey, P. J. & Thakker, R. V. Nov 2015 In : The Lancet Diabetes and Endocrinology. 3, 11, p. 895-905 11 p.

    Research output: Contribution to journalArticle

  33. Defining human pathways of drug metabolism in vivo through the development of a multiple humanized mouse model

    Scheer, N., Kapelyukh, Y., Rode, A., Oswald, S., Busch, D., McLaughlin, L. A., Lin, D., Henderson, C. J. & Wolf, C. R. Nov 2015 In : Drug Metabolism and Disposition. 43, 11, p. 1679-1690 12 p.

    Research output: Contribution to journalArticle

  34. Development of small-molecule Trypanosoma brucei N-myristoyltransferase inhibitors: discovery and optimisation of a novel binding mode

    Spinks, D., Smith, V., Thompson, S., Robinson, D. A., Luksch, T., Smith, A., Torrie, L. S., McElroy, S., Stojanovski, L., Norval, S., Collie, I. T., Hallyburton, I., Rao, B., Brand, S., Brenk, R., Frearson, J. A., Read, K. D., Wyatt, P. G. & Gilbert, I. H. Nov 2015 In : ChemMedChem. 10, 11, p. 1821-1836 16 p.

    Research output: Contribution to journalArticle

  35. Early diagnosis improves outcomes in hepatitis C

    Miller, M. H. & Dillon, J. F. Nov 2015 In : Practitioner. 259, 1787, p. 25-27 3 p.

    Research output: Contribution to journalArticle

  36. Expanding the phenotypic spectrum of Olmsted syndrome

    Wilson, N. J., Cole, C., Milstone, L. M., Kiszewski, A. E., Hansen, C. D., O'Toole, E. A., Schwartz, M. E., McLean, W. H. I. & Smith, F. J. D. Nov 2015 In : Journal of Investigative Dermatology. 135, 11, p. 2879-2883 5 p.

    Research output: Contribution to journalLetter

  37. Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease

    Tebay, L. E., Robertson, H., Durant, S. T., Vitale, S. R., Penning, T. M., Dinkova-Kostova, A. T. & Hayes, J. D. Nov 2015 In : Free Radical Biology and Medicine. 88, Part B, p. 108-146 39 p.

    Research output: Contribution to journalArticle

  38. Neuropathic pain phenotyping by international consensus (NeuroPPIC) for genetic studies: a NeuPSIG systematic review, Delphi survey, and expert panel recommendations

    van Hecke, O., Kamerman, P. R., Attal, N., Baron, R., Bjornsdottir, G., Bennett, D. L. H., Bennett, M. I., Bouhassira, D., Diatchenko, L., Freeman, R., Freynhagen, R., Haanpää, M., Jensen, T. S., Raja, S. N., Rice, A. S. C., Seltzer, Z., Thorgeirsson, T. E., Yarnitsky, D. & Smith, B. H. Nov 2015 In : PAIN. 156, 11, p. 2337-2353 17 p.

    Research output: Contribution to journalArticle

  39. Quantitative assessment of Thiel soft-embalmed human cadavers using shear wave elastography

    Joy, J., McLeod, G., Lee, N., Munirama, S., Corner, G., Eisma, R. & Cochran, S. Nov 2015 In : Annals of Anatomy. 202, p. 52-56 5 p.

    Research output: Contribution to journalArticle

  40. Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin

    McAleer, M. A., Pohler, E., Smith, F. J. D., Wilson, N. J., Cole, C., MacGowan, S., Koetsier, J. L., Godsel, L. M., Harmon, R. M., Gruber, R., Crumrine, D., Elias, P. M., McDermott, M., Butler, K., Broderick, A., Sarig, O., Sprecher, E., Green, K. J., McLean, W. H. I. & Irvine, A. D. Nov 2015 In : Journal of Allergy and Clinical Immunology. 136, 5, p. 1268-1276 9 p.

    Research output: Contribution to journalArticle

  41. The 2015 Garrod Lecture: why is improvement difficult?

    Davey, P. Nov 2015 In : Journal of Antimicrobial Chemotherapy. 70, 11, p. 2931-2944 14 p.

    Research output: Contribution to journalArticle

  42. The emerging role of Nrf2 in mitochondrial function

    Dinkova-Kostova, A. T. & Abramov, A. Y. Nov 2015 In : Free Radical Biology and Medicine. 88, Part B, p. 179-188 10 p.

    Research output: Contribution to journalArticle

  43. The role of pulmonary arterial stiffness in COPD

    Weir-McCall, J. R., Struthers, A. D., Lipworth, B. J. & Houston, J. G. Nov 2015 In : Respiratory Medicine. 109, 11, p. 1381-1390 10 p.

    Research output: Contribution to journalArticle

  44. Trends in socio-economic inequalities in the Scottish diet: 2001-2009

    Barton, K. L., Wrieden, W. L., Sherriff, A., Armstrong, J. & Anderson, A. S. Nov 2015 In : Public Health Nutrition. 18, 16, p. 2970-2980 11 p.

    Research output: Contribution to journalArticle

  45. Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer

    Matula, K., Collie-Duguid, E., Murray, G., Parikh, K., Grabsch, H., Tan, P., Lalwani, S., Garau, R., Ong, Y., Bain, G., Smith, A-D., Urquhart, G., Bielawski, J., Finnegan, M. & Petty, R. 22 Oct 2015 In : BMC Cancer. 15, 1, 14 p., 762

    Research output: Contribution to journalArticle

  46. Epidermal Growth Factor (EGFR) copy number aberrations in esophageal and gastro-esophageal junctional carcinoma

    Dahle-Smith, Å., Stevenson, D., Massie, D., Murray, G. I., Dutton, S. J., Roberts, C., Ferry, D., Osborne, A., Clark, C., Petty, R. D. & Miedzybrodzka, Z. 17 Oct 2015 In : Molecular Cytogenetics. 8, 9 p., 78

    Research output: Contribution to journalArticle

  47. FLCN and AMPK confer resistance to hyperosmotic stress via remodeling of glycogen stores

    Possik, E., Ajisebutu, A., Manteghi, S., Gingras, M-C., Vijayaraghavan, T., Flamand, M., Coull, B., Schmeisser, K., Duchaine, T., van Steensel, M., Hall, D. H. & Pause, A. 6 Oct 2015 In : PLoS Genetics. 11, 10, 18 p., e1005520

    Research output: Contribution to journalArticle

  48. A novel GABAA alpha 5 receptor inhibitor with therapeutic potential

    Lambert, J. J. & 22 others Ling, I., Mihalik, B., Etherington, L-A., Kapus, G., Pálvölgyi, A., Gigler, G., Kertész, S., Gaál, A., Pallagi, K., Kiricsi, P., Szabó, É., Szénási, G., Papp, L., Hársing, L. G., Lévay, G., Spedding, M., Belelli, D., Barkóczy, J., Volk, B., Simig, G., Gacsályi, I. & Antoni, F. A. 5 Oct 2015 In : European Journal of Pharmacology. 764, p. 497-507 11 p.

    Research output: Contribution to journalArticle

  49. A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain

    Meng, W., Deshmukh, H. A., Donnelly, L. A., Wellcome Trust Case Control Consortium 2 (WTCCC2), Surrogate markers for Micro- and Macro-vascular hard endpoints for Innovative diabetes Tools (SUMMIT) study group, Torrance, N., Colhoun, H. M., Palmer, C. N. A. & Smith, B. H. Oct 2015 In : EBioMedicine. 2, 10, p. 1386-1393 8 p.

    Research output: Contribution to journalArticle

  50. Biomarkers of rapid chronic kidney disease progression in type 2 diabetes

    Looker, H. C., Colombo, M., Hess, S., Brosnan, M. J., Farran, B., Dalton, R. N., Wong, M. C., Turner, C., Palmer, C. N. A., Nogoceke, E., Groop, L., Salomaa, V., Dunger, D. B., Agakov, F., McKeigue, P. M., Colhoun, H. M. & on behalf of the SUMMIT Investigators Oct 2015 In : Kidney International. 88, 4, p. 888-896 9 p.

    Research output: Contribution to journalArticle

  51. Comparative ergonomic workflow and user experience analysis of MRI versus fluoroscopy-guided vascular interventions: an iliac angioplasty exemplar case study

    Fernández-Gutiérrez, F., Martínez, S., Rube, M. A., Cox, B. F., Fatahi, M., Scott-Brown, K. C., Houston, J. G., McLeod, H., White, R. D., French, K., Gueorguieva, M., Immel, E. & Melzer, A. Oct 2015 In : International Journal of Computer Assisted Radiology and Surgery. 10, 10, p. 1639-1650 12 p.

    Research output: Contribution to journalArticle

  52. Elastic properties of Thiel-embalmed human ankle tendon and ligament

    Liao, X., Kemp, S., Corner, G., Eisma, R. & Huang, Z. Oct 2015 In : Clinical Anatomy. 28, 7, p. 917-924 8 p.

    Research output: Contribution to journalArticle

  53. Global economic impact of dental diseases

    Listl, S., Galloway, J., Mossey, P. A. & Marcenes, W. Oct 2015 In : Journal of Dental Research. 94, 10, p. 1355-1361 7 p.

    Research output: Contribution to journalArticle

  54. Management of noncardiac comorbidities in chronic heart failure

    Chong, V. H., Singh, J., Parry, H., Saunders, J., Chowdhury, F., Mancini, D. M. & Lang, C. C. Oct 2015 In : Cardiovascular Therapeutics. 33, 5, p. 300-315 16 p.

    Research output: Contribution to journalArticle

  55. Secreted mucins and airway bacterial colonization in non-CF bronchiectasis

    Sibila, O., Suarez-Cuartin, G., Rodrigo-Troyano, A., Fardon, T. C., Finch, S., Mateus, E. F., Garcia-Bellmunt, L., Castillo, D., Vidal, S., Sanchez-Reus, F., Restrepo, M. I. & Chalmers, J. D. Oct 2015 In : Respirology . 20, 7, p. 1082-1088 7 p.

    Research output: Contribution to journalArticle

  56. Mice lacking beta2-integrin function remain glucose tolerant in spite of insulin resistance, neutrophil infiltration and inflammation

    Meakin, P. J., Morrison, V. L., Sneddon, C. C., Savinko, T., Uotila, L., Jalicy, S. M., Gabriel, J. L., Kang, L., Ashford, M. L. J. & Fagerholm, S. C. 25 Sep 2015 In : PLoS ONE. 10, 9, 15 p., e0138872

    Research output: Contribution to journalArticle

  57. Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action

    Kostov, R. V., Knatko, E., McLaughlin, L., Henderson, C., Zheng, S., Huang, J. T-J., Honda, T. & Dinkova-Kostova, A. T. 25 Sep 2015 In : Biochemical and Biophysical Research Communications. 465, 3, p. 402-407 6 p.

    Research output: Contribution to journalArticle

  58. Cohort comparison study of cardiac disease and atherosclerotic burden in type 2 diabetic adults using whole body cardiovascular magnetic resonance imaging

    Duce, S. L., Weir-McCall, J. R., Gandy, S. J., Matthew, S. Z., Cassidy, D. B., McCormick, L., Rauchhaus, P., Looker, H., Colhoun, H. M. & Houston, J. G. 18 Sep 2015 In : Cardiovascular Diabetology. 14, 11 p., 122

    Research output: Contribution to journalArticle

  59. Lysyl hydroxylase 3 localizes to epidermal basement membrane and Is reduced in patients with Recessive Dystrophic Epidermolysis Bullosa

    Watt, S. A., Dayal, J. H. S., Wright, S., Riddle, M., Pourreyron, C., McMillan, J. R., Kimble, R. M., Prisco, M., Gartner, U., Warbrick, E., McLean, W. H. I., Leigh, I. M., McGrath, J. A., Salas-Alanis, J. C., Tolar, J. & South, A. P. 18 Sep 2015 In : PLoS ONE. 10, 9, 15 p., e0137639

    Research output: Contribution to journalArticle

  60. Accuracy of patient self-report of stroke: A systematic review from the UK biobank stroke outcomes group

    Woodfield, R. , Sudlow, C. , Al-Shahi Salman, R. , Beral, V. , Chen, Y. , Chen, Z. , Dennis, M. , Kroll, M. , Green, J. , Lewington, S. , Rothwell, P. , Wardlaw, J. , Whiteley, W. , Wild, S. , Wright, L. , Zhang, Q. , Flaig, R. , Danesh, J. , Allen, N. , Atkinson, M. & 22 others Blaveri, E., Brannan, R., Brayne, C., Brophy, S., Chaturvedi, N., Collins, R., De Lusignan, S., Denaxas, S., Desai, P., Eastwood, S., Gallacher, J., Hemingway, H., Hotopf, M., Landray, M., Lyons, R., McGilchrist, M., Moller, H., O'Neil, T., Pringle, M., Sprosen, T., Strachan, D. & Sullivan, F. 10 Sep 2015 In : PLoS ONE. 10, e0137538

    Research output: Contribution to journalArticle

  61. A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial

    Harrison, E. F., Haines, R. H., Cowdell, F., Sach, T. H., Dean, T., Pollock, I., Burrows, N. P., Buckley, H., Batchelor, J., Williams, H. C., Lawton, S., Brown, S. J., Bradshaw, L. E., Ahmed, A., Montgomery, A. A., Mitchell, E. J. & Thomas, K. S. 2 Sep 2015 In : Trials. 16, 12 p., 390

    Research output: Contribution to journalArticle

  62. Construction of a linked health and social care database resource: lessons on process, content and culture

    Witham, M. D., Frost, H., McMurdo, M., Donnan, P. T. & McGilchrist, M. 1 Sep 2015 In : Informatics for Health and Social Care. 40, 3, p. 229-239 11 p.

    Research output: Contribution to journalArticle

  63. Giving structure to the biofilm matrix: an overview of individual strategies and emerging common themes

    Hobley, L., Harkins, C., MacPhee, C. E. & Stanley-Wall, N. R. 1 Sep 2015 In : FEMS Microbiology Reviews. 39, 5, p. 649-669 21 p.

    Research output: Contribution to journalArticle

  64. Multiple quantum filtered 23Na NMR in the Langendorff perfused mouse heart: Ratio of triple/double quantum filtered signals correlate with [Na]i

    Eykyn, T. R., Aksentijević, D., Aughton, K. L., Southworth, R., Fuller, W. & Shattock, M. J. 1 Sep 2015 In : Journal of Molecular and Cellular Cardiology. 86, p. 95-101 7 p.

    Research output: Contribution to journalArticle

  65. A systematic review and meta-analysis of ultrasound versus electrical stimulation for peripheral nerve location and blockade

    Munirama, S. & McLeod, G. Sep 2015 In : Anaesthesia. 70, 9, p. 1084-1091 8 p.

    Research output: Contribution to journalArticle

  66. Are NICE guidelines losing their impartiality?

    Coghill, D. Sep 2015 In : British Journal of Psychiatry. 207, 3, p. 271 1 p.

    Research output: Contribution to journalLetter

  67. Dignity and patient-centred care for people with palliative care needs in the acute hospital setting: A systematic review

    Pringle, J., Johnston, B. & Buchanan, D. Sep 2015 In : Palliative Medicine. 29, 8, p. 675-694 20 p.

    Research output: Contribution to journalArticle

  68. Is photodynamic diagnostic flexible ureterorenoscopy suitable for a patient presenting with chronic actinic dermatitis?

    Valentine, R., Kata, S., Ibbotson, S., Nabi, G. & Moseley, H. Sep 2015 In : Photodermatology, Photoimmunology & Photomedicine. 31, 5, p. 279-281 3 p.

    Research output: Contribution to journalLetter

  69. Localisation and stress-induced plasticity of GABAA receptor subunits within the cellular networks of the mouse dorsal raphe nucleus

    Corteen, N. L., Carter, J. A., Rudolph, U., Belelli, D., Lambert, J. J. & Swinny, J. D. Sep 2015 In : Brain Structure and Function. 220, 5, p. 2739-2763 25 p.

    Research output: Contribution to journalArticle

  70. Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study

    Belch, J. & 20 others Shore, A. C., Colhoun, H. M., Natali, A., Palombo, C., Östling, G., Aizawa, K., Kennbäck, C., Casanova, F., Persson, M., Gates, P. E., Kahn, F., Looker, H. C., Adams, F., Pinnoli, S., Venturi, E., Morizzo, C., Goncalves, I., Ladenvall, C., Nilsson, J. & on behalf of the SUMMIT consortium Sep 2015 In : Journal of Internal Medicine. 278, 3, p. 291-302 12 p.

    Research output: Contribution to journalArticle

  71. Novel CARD11 mutations in human cutaneous squamous cell carcinoma lead to aberrant NF-κB regulation

    Watt, S. A., Purdie, K. J., den Breems, N. Y., Dimon, M., Arron, S. T., McHugh, A. T., Xue, D. J., Dayal, J. H. S., Proby, C. M., Harwood, C. A., Leigh, I. M. & South, A. P. Sep 2015 In : American Journal of Pathology. 185, 9, p. 2354-2363 10 p.

    Research output: Contribution to journalArticle

  72. Screen-printed ultrasonic 2-D matrix array transducers for microparticle manipulation

    Qiu, Y., Wang, H., Gebhardt, S., Bolhovitins, A., Démoré, C. E. M., Schönecker, A. & Cochran, S. Sep 2015 In : Ultrasonics. 62, p. 136-146 11 p.

    Research output: Contribution to journalArticle

  73. Total levels, localization patterns, and proportions of sperm exhibiting phospholipase C zeta are significantly correlated with fertilization rates after intracytoplasmic sperm injection

    Yelumalai, S., Yeste, M., Jones, C., Amdani, S. N., Kashir, J., Mounce, G., Martins Da Silva, S. J., Barratt, C. L., McVeigh, E. & Coward, K. Sep 2015 In : Fertility and Sterility. 104, 3, p. 561-568.e4 12 p.

    Research output: Contribution to journalArticle

  74. mHealth applications for diabetes – user preference and implications for app development

    Conway, N., Campbell, I., Forbes, P., Cunningham, S. & Wake, D. 26 Aug 2015

    Research output: Contribution to conferencePoster

  75. Synthesis of carbohydrate capped silicon nanoparticles and their reduced cytotoxicity, in vivo toxicity, and cellular uptake

    Ahire, J. H., Behray, M., Webster, C. A., Wang, Q., Sherwood, V., Saengkrit, N., Ruktanonchai, U., Woramongkolchai, N. & Chao, Y. 26 Aug 2015 In : Advanced Healthcare Materials. 4, 12, p. 1877-1886 10 p.

    Research output: Contribution to journalArticle

  76. Erratum to: Long-acting methylphenidate formulations in the treatment of attention-deficit/hyperactivity disorder: a systematic review of head-to-head studies

    Coghill, D., Banaschewski, T., Zuddas, A., Pelaz, A., Gagliano, A. & Doepfner, M. 25 Aug 2015 In : BMC Psychiatry. 15, 1 p., 202

    Research output: Contribution to journalArticle

  77. The fanconi anemia DNA repair pathway is regulated by an interaction between ubiquitin and the E2-like fold domain of FANCL

    Miles, J. A., Frost, M. G., Carroll, E., Rowe, M. L., Howard, M. J., Sidhu, A., Chaugule, V. K., Alpi, A. F. & Walden, H. 21 Aug 2015 In : Journal of Biological Chemistry. 290, 34, p. 20995-21006 12 p.

    Research output: Contribution to journalArticle

  78. Cezanne regulates E2F1-dependent HIF2α expression

    Moniz, S., Bandarra, D., Biddlestone, J., Campbell, K. J., Komander, D., Bremm, A. & Rocha, S. 15 Aug 2015 In : Journal of Cell Science. 128, 16, p. 3082-3093 12 p.

    Research output: Contribution to journalArticle

  79. Selective expression of the MAPK phosphatase Dusp9/MKP-4 in mouse plasmacytoid dendritic cells and regulation of IFNβ production1

    Niedzielska, M., Raffi, F. A. M., Tel, J., Muench, S., Jozefowski, K., Alati, N., Lahl, K., Mages, J., Billmeier, U., Schiemann, M., Appelt, U. K., Wirtz, S., Sparwasser, T., Hochrein, H., Figdor, C. G., Keyse, S. M. & Lang, R. 15 Aug 2015 In : Journal of Immunology. 195, 4, p. 1753-1762 10 p.

    Research output: Contribution to journalArticle

  80. The selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expression

    Zhang, Y., Li, S., Xiang, Y., Qiu, L., Zhao, H. & Hayes, J. D. 13 Aug 2015 In : Scientific Reports. 5, 30 p., 12983

    Research output: Contribution to journalArticle

  81. Monotherapy versus dual therapy for the initial treatment of hypertension (PATHWAY-1): a randomised double-blind controlled trial

    MacDonald, T. M., Williams, B., Caulfield, M., Cruickshank, J. K., McInnes, G., Sever, P., Webb, D. J., Mackenzie, I. S., Salsbury, J., Morant, S., Ford, I. & Brown, M. J. 7 Aug 2015 In : BMJ Open. 5, 8, 7 p., e007645

    Research output: Contribution to journalArticle

  82. The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic

    O'Connell, M. A. & Hayes, J. D. 3 Aug 2015 In : Biochemical Society Transactions. 43, 4, p. 687-689 3 p.

    Research output: Contribution to journalArticle

  83. The spatiotemporal regulation of the Keap1-Nrf2 pathway and its importance in cellular bioenergetics

    Dinkova-Kostova, A. T., Baird, L., Holmström, K. M., Meyer, C. J. & Abramov, A. Y. 3 Aug 2015 In : Biochemical Society Transactions. 43, 4, p. 602-610 9 p.

    Research output: Contribution to journalArticle

  84. Bacillus anthracis meningitis during an outbreak of injectional anthrax, Scotland, UK

    Dewar, S., Weir-McCall, J. R., Batchelor, L., Cole, S. & Parcell, B. J. 1 Aug 2015 In : Clinical Microbiology and Infection. 21, 8, p. e49-e50 2 p.

    Research output: Contribution to journalArticle

  85. Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation

    Kazlauskaite, A., Martínez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H. & Muqit, M. M. K. 1 Aug 2015 In : EMBO Reports. 16, 8, p. 939-954 16 p.

    Research output: Contribution to journalArticle

  86. Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)?: Study protocol for a randomized controlled trial

    Witham, M. D., Band, M. M., Littleford, R. C., Avenell, A., Soiza, R. L., McMurdo, M. E. T., Sumukadas, D., Ogston, S. A., Lamb, E. J., Hampson, G., McNamee, P. & BiCARB study group 1 Aug 2015 In : Trials. 16, 326

    Research output: Contribution to journalArticle

  87. Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)? Study protocol for a randomized controlled trial

    Witham, M. D., Band, M. M., Littleford, R. C., Avenell, A., Soiza, R. L., McMurdo, M. E. T., Sumukadas, D., Ogston, S. A., Lamb, E. J., Hampson, G., McNamee, P. & for the BiCARB study group 1 Aug 2015 In : Trials. 16, 9 p., 326

    Research output: Contribution to journalArticle

  88. Insightful practice: a robust measure of medical students' professional response to feedback on their performance

    Murphy, D., Aitchison, P., Hernandez Santiago, V., Davey, P., Mires, G. & Nathwani, D. 1 Aug 2015 In : BMC Medical Education. 15, 1, 11 p., 125

    Research output: Contribution to journalArticle

  89. Agonist- and antagonist-induced up-regulation of surface 5-HT3A receptors

    Morton, R. A., Baptista-Hon, D. T., Hales, T. G. & Lovinger, D. M. Aug 2015 In : British Journal of Pharmacology. 172, 16, p. 4066-4077 12 p.

    Research output: Contribution to journalArticle

  90. Conspecific recognition and aggression reduction to familiars in newly weaned, socially plastic mammals

    Robinson, K. J., Twiss, S. D., Hazon, N., Moss, S., Lonergan, M. & Pomeroy, P. P. Aug 2015 In : Behavioral Ecology and Sociobiology. 69, 8, p. 1383-1394 12 p.

    Research output: Contribution to journalArticle

  91. Correlation between reversal of DNA methylation and clinical symptoms in psoriatic epidermis following narrow-band UVB phototherapy

    Gu, X., Nylander, E., Coates, P. J., Fahraeus, R. & Nylander, K. Aug 2015 In : Journal of Investigative Dermatology. 135, 8, p. 2077-2083 7 p.

    Research output: Contribution to journalArticle

  92. Could tuning of the inhibitory tone involve graded changes in neuronal chloride transport?

    Titz, S., Sammler, E. M. & Hormuzdi, S. G. Aug 2015 In : Neuropharmacology. 95, p. 321-331 11 p.

    Research output: Contribution to journalArticle

  93. Faecal haemoglobin concentrations do vary across geography as well as with age and sex: ramifications for colorectal cancer screening

    Fraser, C. G., Auge, J. M. & on behalf of the PROCOLON Group Aug 2015 In : Clinical Chemistry and Laboratory Medicine. 53, 9, p. e235-e237 3 p.

    Research output: Contribution to journalLetter

  94. Identifying the unmet supportive care needs of men living with and beyond prostate cancer: A systematic review

    Paterson, C., Robertson, A., Smith, A. & Nabi, G. Aug 2015 In : European Journal of Oncology Nursing. 19, 4, p. 405-418 14 p.

    Research output: Contribution to journalArticle

  95. Impact of left ventricular hypertrophy on survival in chronic obstructive pulmonary disease

    Short, P. M., Anderson, W. J., Elder, D. H. J., Struthers, A. D. & Lipworth, B. J. Aug 2015 In : Lung. 193, 4, p. 487-495 9 p.

    Research output: Contribution to journalArticle

  96. No strong relationship between components of the lectin pathway of complement and susceptibility to pulmonary tuberculosis

    Chalmers, J. D., Matsushita, M., Kilpatrick, D. C. & Hill, A. T. Aug 2015 In : Inflammation. 38, 4, p. 1731-1737 7 p.

    Research output: Contribution to journalArticle

  97. Poster advertisements in practice waiting rooms to recruit patients to the Treatment In Morning vs. Evening (TIME) online study

    Rorie, D., Flynn, R., McConnachie, L., Mackenzie, I. S. & MacDonald, T. M. Aug 2015 In : British Journal of Clinical Pharmacology. 80, 2, p. 325-326

    Research output: Contribution to journalLetter

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