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  1. Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

    Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J. 20 Nov 2016 New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January, p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  2. During postnatal development endogenous neurosteroids influence GABA-ergic neurotransmission of mouse cortical neurons

    Brown, A. R., Mitchell, S., Peden, D. R., Herd, M. B., Seifi, M., Swinny, J. D., Belelli, D. & Lambert, J. Apr 2016 In : Neuropharmacology. 103, p. 163-173 11 p.

    Research output: Contribution to journalArticle

  3. Association between allopurinol use and hip fracture in older patients

    Basu, U., Goodbrand, J., McMurdo, M. E. T., Donnan, P. T., McGilchrist, M., Frost, H., George, J. & Witham, M. D. Mar 2016 In : Bone. 84, p. 189-193 5 p.

    Research output: Contribution to journalArticle

  4. A spontaneous increase in intracellular Ca2+ in metaphase II human oocytes in vitro can be prevented by drugs targeting ATP-sensitive K+ channels

    Fernandes, G., Dasai, N., Kozlova, N., Mojadadi, A., Gall, M., Drew, E., Barratt, E., Madamidola, O. A., Brown, S. G., Milne, A. M., Martins Da Silva, S. J., Whalley, K. M., Barratt, C. L. R. & Jovanovic, A. Feb 2016 In : Human Reproduction. 31, 2, p. 287-297 11 p.

    Research output: Contribution to journalArticle

  5. Effect of atorvastatin on glycaemia progression in patients with diabetes: an analysis from the Collaborative Atorvastatin in Diabetes Trial (CARDS)

    Livingstone, S. J., Looker, H. C., Akbar, T., Betteridge, D. J., Durrington, P. N., Hitman, G. A., Neil, H. A. W., Fuller, J. H. & Colhoun, H. M. Feb 2016 In : Diabetologia. 59, 2, p. 299-306 8 p.

    Research output: Contribution to journalArticle

  6. Can angiotensin-converting enzyme inhibitors reduce the incidence, severity, and duration of radiation proctitis?

    Alashkham, A., Paterson, C., Rauchhaus, P. & Nabi, G. Jan 2016 In : International Journal of Radiation Oncology Biology Physics. 94, 1, p. 93-101 9 p.

    Research output: Contribution to journalArticle

  7. Clinical utility of one versus two faecal immunochemical test samples in the detection of advanced colorectal neoplasia in symptomatic patients

    Auge, J. M., Fraser, C. G., Rodriguez, C., Roset, A., Lopez-Ceron, M., Grau, J., Castells, A. & Jimenez, W. Jan 2016 In : Clinical Chemistry and Laboratory Medicine. 54, 1, p. 125-132 8 p.

    Research output: Contribution to journalArticle

  8. From mouse to man: Predicting biased effects of beta-blockers in asthma

    Lipworth, B. J., Anderson, W. J. & Short, P. M. Jan 2016 In : British Journal of Pharmacology. 173, 1, p. 248-249 2 p.

    Research output: Contribution to journalArticle

  9. Inhaled corticosteroid dose-response on blood eosinophils in asthma

    Lipworth, B., Jabbal, S., Manoharan, A., Anderson, W. & Short, P. Jan 2016 In : The Lancet Respiratory Medicine. 4, 1, p. e1

    Research output: Contribution to journalArticle

  10. Re: A proposal to standardize reporting units for fecal immunochemical tests for hemoglobin

    Fraser, C. G., Rapi, S. & Rubeca, T. Jan 2016 In : Journal of the National Cancer Institute. 108, 1, 2 p., djv312

    Research output: Contribution to journalLetter

  11. Effects of adding Tiotropium or Aclidinium as triple therapy using impulse oscillometry in COPD

    Manoharan, A., Morrison, A. E. & Lipworth, B. 2016 In : Lung. 8 p.

    Research output: Contribution to journalArticle

  12. Structured antibiotic 'time-out' audits as recommended by the CDC reduce antibiotic use and costs

    Davey, P. G. 2016 In : Evidence-Based Nursing. 19, 1, p. 24 1 p.

    Research output: Contribution to journalArticle

  13. DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions

    Huang, W. , Thomas, B. , Flynn, R. A. , Gavzy, S. J. , Wu, L. , Kim, S. V. , Hall, J. A. , Miraldi, E. R. , Ng, C. P. , Rigo, F. , Meadows, S. , Montoya, N. R. , Herrera, N. G. , Domingos, A. I. , Rastinejad, F. , Myers, R. M. , Fuller-Pace, F. V. , Bonneau, R. , Chang, H. Y. , Acuto, O. & 1 others Littman, D. R. 24 Dec 2015 In : Nature. 528, 7583, p. 517-522 6 p., 16193

    Research output: Contribution to journalArticle

  14. The copper binding properties of metformin - QCM-D, XPS and nanobead agglomeration

    Quan, X., Uddin, R., Heiskanen, A., Parmvi, M., Nilson, K., Donolato, M., Hansen, M. F., Rena, G. & Boisen, A. 18 Dec 2015 In : Chemical Communications. 51, 97, p. 17313-17316 4 p.

    Research output: Contribution to journalArticle

  15. Functional piezocrystal characterisation under varying conditions

    Liao, X., Qiu, Z., Jiang, T., Sadiq, M. R., Huang, Z., Demore, C. E. M. & Cochran, S. 2 Dec 2015 In : Materials. 8, 12, p. 8304-8326 23 p.

    Research output: Contribution to journalArticle

  16. Decision support for diabetes: implementation and evaluation of the EBMeDS project within NHS Scotland

    Conway, N., Cunningham, S., Forbes, P., Shaik, F., Emslie-Smith, A., Wales, A. & Wake, D. 1 Dec 2015

    Research output: Contribution to conferencePoster

  17. Health state utilities associated with attributes of treatments for hepatitis C

    Matza, L. S., Sapra, S. J., Dillon, J. F., Kalsekar, A., Davies, E. W., Devine, M. K., Jordan, J. B., Landrian, A. S. & Feeny, D. H. 1 Dec 2015 In : European Journal of Health Economics. 16, 9, p. 1005-1018 14 p.

    Research output: Contribution to journalArticle

  18. Clinical practice guidelines and the older patient: wake up call for geriatricians

    Vilches-Moraga, A., Martinez-Velilla, N., Cherubini, A., McMurdo, M., Singh, I. & Pattison, T. Dec 2015 In : European Geriatric Medicine. 6, 6, p. 513-514 2 p.

    Research output: Contribution to journalEditorial

  19. Etiology of non-cystic fibrosis bronchiectasis in adults and its correlation to disease severity

    Lonni, S., Chalmers, J. D., Goeminne, P. C., McDonnell, M. J., Dimakou, K., De Soyza, A., Polverino, E., Van De Kerkhove, C., Rutherford, R., Davison, J., Rosales, E., Pesci, A., Restrepo, M. I., Torres, A. & Aliberti, S. Dec 2015 In : Annals of the American Thoracic Society. 12, 12, p. 1764-1770 7 p.

    Research output: Contribution to journalArticle

  20. Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis

    Riethmuller, C., McAleer, M. A., Koppes, S. A., Abdayem, R., Franz, J., Haftek, M., Campbell, L. E., MacCallum, S. F., McLean, W. H. I., Irvine, A. D. & Kezic, S. Dec 2015 In : Journal of Allergy and Clinical Immunology. 136, 6, p. 1573-1580.e2 10 p.

    Research output: Contribution to journalArticle

  21. Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

    Morris, A. P. & 97 others Artigas, M. S., Wain, L. V., Miller, S., Kheirallah, A. K., Huffman, J. E., Ntalla, I., Shrine, N., Obeidat, M., Trochet, H., McArdle, W. L., Alves, A. C., Hui, J., Zhao, J. H., Joshi, P. K., Teumer, A., Albrecht, E., Imboden, M., Rawal, R., Lopez, L. M., Marten, J., Enroth, S., Surakka, I., Polasek, O., Lyytikäinen, L. P., Granell, R., Hysi, P. G., Flexeder, C., Mahajan, A., Beilby, J., Bossé, Y., Brandsma, C. A., Campbell, H., Gieger, C., Gläser, S., González, J. R., Grallert, H., Hammond, C. J., Harris, S. E., Hartikainen, A. L., Heliövaara, M., Henderson, J., Hocking, L., Horikoshi, M., Hutri-Kähönen, N., Ingelsson, E., Johansson, Å., Kemp, J. P., Kolcic, I., Kumar, A., Lind, L., Melén, E., Musk, A. W., Navarro, P., Nickle, D. C., Padmanabhan, S., Raitakari, O. T., Ried, J. S., Ripatti, S., Schulz, H., Scott, R. A., Sin, D. D., Starr, J. M., Viñuela, A., Völzke, H., Wild, S. H., Wright, A. F., Zemunik, T., Jarvis, D. L., Spector, T. D., Evans, D. M., Lehtimäki, T., Vitart, V., Kähönen, M., Gyllensten, U., Rudan, I., Deary, I. J., Karrasch, S., Probst-Hensch, N. M., Heinrich, J., Stubbe, B., Wilson, J. F., Wareham, N. J., James, A. L., Jarvelin, M. R., Hayward, C., Sayers, I., Strachan, D. P., Hall, I. P., Tobin, M. D., Deloukas, P., Hansell, A. L., Hubbard, R., Jackson, V. E., Marchini, J., Pavord, I., Thomson, N. C. & Zeggini, E. Dec 2015 In : Nature Communications. 6, 89658

    Research output: Contribution to journalArticle

  22. The Concise Guide to PHARMACOLOGY 2015/16: Nuclear hormone receptors

    Alexander, S. P., Cidlowski, J. A., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C. & Davies, J. A. Dec 2015 In : British Journal of Pharmacology. 172, 24, p. 5956-5978 23 p.

    Research output: Contribution to journalArticle

  23. The Concise Guide to PHARMACOLOGY 2015/16: Overview

    Alexander, S. P. H., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C., Buneman, O. P., Catterall, W. A., Cidlowski, J. A., Davenport, A. P., Fabbro, D., Fan, G., McGrath, J. C., Spedding, M. & Davies, J. A. Dec 2015 In : British Journal of Pharmacology. 172, 24, p. 5729-5743 15 p.

    Research output: Contribution to journalArticle

  24. The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors

    Alexander, S. P. H., Davenport, A. P., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C. & Davies, J. A. Dec 2015 In : British Journal of Pharmacology. 172, 24, p. 5744-5869 126 p.

    Research output: Contribution to journalArticle

  25. Towards an ICF core set for ADHD: a worldwide expert survey on ability and disability

    de Schipper, E., Mahdi, S., Coghill, D., de Vries, P. J., Gau, S. S. F., Granlund, M., Holtmann, M., Karande, S., Levy, F., Almodayfer, O., Rohde, L., Tannock, R. & Bölte, S. Dec 2015 In : European Child & Adolescent Psychiatry. 24, 12, p. 1509-1521 13 p.

    Research output: Contribution to journalArticle

  26. Implementation of the Lancet Standing Commission on liver disease in the UK

    Williams, R. , Ashton, K. , Aspinall, R. , Bellis, M. A. , Bosanquet, J. , Cramp, M. E. , Day, N. , Dhawan, A. , Dillon, J. , Dyson, J. , Ferguson, J. , Foster, G. , Gilmore, I. , Glynn, M. , Guthrie, J. A. , Hudson, M. , Kelly, D. , Langford, A. , Newsome, P. , O'Grady, J. & 5 others Pryke, R., Ryder, S., Samyn, M., Sheron, N. & Verne, J. 21 Nov 2015 In : Lancet. 386, 10008, p. 2098-2111 14 p.

    Research output: Contribution to journalArticle

  27. Risk of postoperative acute kidney injury in patients undergoing orthopaedic surgery—development and validation of a risk score and effect of acute kidney injury on survival: observational cohort study

    Bell, S., Dekker, F. W., Vadiveloo, T., Marwick, C., Deshmukh, H., Donnan, P. T. & Van Diepen, M. 11 Nov 2015 In : BMJ. 351, 9 p., h5639

    Research output: Contribution to journalArticle

  28. Activation status of the Pregnane X Receptor influences Vemurafenib availability in humanized mouse models

    MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R. 1 Nov 2015 In : Cancer Research. 75, 21, p. 4573-4581 10 p.

    Research output: Contribution to journalArticle

  29. Strategies for the treatment of Hepatitis C in an era of interferon-free therapies: what public health outcomes do we value most?

    Innes, H., Goldberg, D., Dillon, J. & Hutchinson, S. J. 1 Nov 2015 In : Gut. 64, 11, p. 1800-1809 10 p.

    Research output: Contribution to journalArticle

  30. Association between kidney function, rehabilitation outcome, and survival in older patients discharged from inpatient rehabilitation

    Doyle, E. M., Sloan, J. M., Goodbrand, J. A., McMurdo, M. E. T., Donnan, P. T., McGilchrist, M. M., Frost, H. & Witham, M. D. Nov 2015 In : American Journal of Kidney Diseases. 66, 5, p. 768-774 7 p.

    Research output: Contribution to journalArticle

  31. Association between retinal vasculature and muscle mass in older people

    Sumukadas, D., McMurdo, M., Pieretti, I., Ballerini, L., Price, R., Wilson, P., Doney, A., Leese, G. & Trucco, E. Nov 2015 In : Archives of Gerontology and Geriatrics. 61, 3, p. 425-428 4 p.

    Research output: Contribution to journalArticle

  32. Challenges and controversies in management of pancreatic neuroendocrine tumours in patients with MEN1

    Yates, C. J., Newey, P. J. & Thakker, R. V. Nov 2015 In : The Lancet Diabetes and Endocrinology. 3, 11, p. 895-905 11 p.

    Research output: Contribution to journalArticle

  33. Defining human pathways of drug metabolism in vivo through the development of a multiple humanized mouse model

    Scheer, N., Kapelyukh, Y., Rode, A., Oswald, S., Busch, D., McLaughlin, L. A., Lin, D., Henderson, C. J. & Wolf, C. R. Nov 2015 In : Drug Metabolism and Disposition. 43, 11, p. 1679-1690 12 p.

    Research output: Contribution to journalArticle

  34. Development of small-molecule Trypanosoma brucei N-myristoyltransferase inhibitors: discovery and optimisation of a novel binding mode

    Spinks, D., Smith, V., Thompson, S., Robinson, D. A., Luksch, T., Smith, A., Torrie, L. S., McElroy, S., Stojanovski, L., Norval, S., Collie, I. T., Hallyburton, I., Rao, B., Brand, S., Brenk, R., Frearson, J. A., Read, K. D., Wyatt, P. G. & Gilbert, I. H. Nov 2015 In : ChemMedChem. 10, 11, p. 1821-1836 16 p.

    Research output: Contribution to journalArticle

  35. Early diagnosis improves outcomes in hepatitis C

    Miller, M. H. & Dillon, J. F. Nov 2015 In : Practitioner. 259, 1787, p. 25-27 3 p.

    Research output: Contribution to journalArticle

  36. Expanding the phenotypic spectrum of Olmsted syndrome

    Wilson, N. J., Cole, C., Milstone, L. M., Kiszewski, A. E., Hansen, C. D., O'Toole, E. A., Schwartz, M. E., McLean, W. H. I. & Smith, F. J. D. Nov 2015 In : Journal of Investigative Dermatology. 135, 11, p. 2879-2883 5 p.

    Research output: Contribution to journalLetter

  37. Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease

    Tebay, L. E., Robertson, H., Durant, S. T., Vitale, S. R., Penning, T. M., Dinkova-Kostova, A. T. & Hayes, J. D. Nov 2015 In : Free Radical Biology and Medicine. 88, Part B, p. 108-146 39 p.

    Research output: Contribution to journalArticle

  38. Neuropathic pain phenotyping by international consensus (NeuroPPIC) for genetic studies: a NeuPSIG systematic review, Delphi survey, and expert panel recommendations

    van Hecke, O., Kamerman, P. R., Attal, N., Baron, R., Bjornsdottir, G., Bennett, D. L. H., Bennett, M. I., Bouhassira, D., Diatchenko, L., Freeman, R., Freynhagen, R., Haanpää, M., Jensen, T. S., Raja, S. N., Rice, A. S. C., Seltzer, Z., Thorgeirsson, T. E., Yarnitsky, D. & Smith, B. H. Nov 2015 In : PAIN. 156, 11, p. 2337-2353 17 p.

    Research output: Contribution to journalArticle

  39. Quantitative assessment of Thiel soft-embalmed human cadavers using shear wave elastography

    Joy, J., McLeod, G., Lee, N., Munirama, S., Corner, G., Eisma, R. & Cochran, S. Nov 2015 In : Annals of Anatomy. 202, p. 52-56 5 p.

    Research output: Contribution to journalArticle

  40. Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin

    McAleer, M. A., Pohler, E., Smith, F. J. D., Wilson, N. J., Cole, C., MacGowan, S., Koetsier, J. L., Godsel, L. M., Harmon, R. M., Gruber, R., Crumrine, D., Elias, P. M., McDermott, M., Butler, K., Broderick, A., Sarig, O., Sprecher, E., Green, K. J., McLean, W. H. I. & Irvine, A. D. Nov 2015 In : Journal of Allergy and Clinical Immunology. 136, 5, p. 1268-1276 9 p.

    Research output: Contribution to journalArticle

  41. The 2015 Garrod Lecture: why is improvement difficult?

    Davey, P. Nov 2015 In : Journal of Antimicrobial Chemotherapy. 70, 11, p. 2931-2944 14 p.

    Research output: Contribution to journalArticle

  42. The emerging role of Nrf2 in mitochondrial function

    Dinkova-Kostova, A. T. & Abramov, A. Y. Nov 2015 In : Free Radical Biology and Medicine. 88, Part B, p. 179-188 10 p.

    Research output: Contribution to journalArticle

  43. The role of pulmonary arterial stiffness in COPD

    Weir-McCall, J. R., Struthers, A. D., Lipworth, B. J. & Houston, J. G. Nov 2015 In : Respiratory Medicine. 109, 11, p. 1381-1390 10 p.

    Research output: Contribution to journalArticle

  44. Trends in socio-economic inequalities in the Scottish diet: 2001-2009

    Barton, K. L., Wrieden, W. L., Sherriff, A., Armstrong, J. & Anderson, A. S. Nov 2015 In : Public Health Nutrition. 18, 16, p. 2970-2980 11 p.

    Research output: Contribution to journalArticle

  45. Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer

    Matula, K., Collie-Duguid, E., Murray, G., Parikh, K., Grabsch, H., Tan, P., Lalwani, S., Garau, R., Ong, Y., Bain, G., Smith, A-D., Urquhart, G., Bielawski, J., Finnegan, M. & Petty, R. 22 Oct 2015 In : BMC Cancer. 15, 1, 14 p., 762

    Research output: Contribution to journalArticle

  46. Epidermal Growth Factor (EGFR) copy number aberrations in esophageal and gastro-esophageal junctional carcinoma

    Dahle-Smith, Å., Stevenson, D., Massie, D., Murray, G. I., Dutton, S. J., Roberts, C., Ferry, D., Osborne, A., Clark, C., Petty, R. D. & Miedzybrodzka, Z. 17 Oct 2015 In : Molecular Cytogenetics. 8, 9 p., 78

    Research output: Contribution to journalArticle

  47. FLCN and AMPK confer resistance to hyperosmotic stress via remodeling of glycogen stores

    Possik, E., Ajisebutu, A., Manteghi, S., Gingras, M-C., Vijayaraghavan, T., Flamand, M., Coull, B., Schmeisser, K., Duchaine, T., van Steensel, M., Hall, D. H. & Pause, A. 6 Oct 2015 In : PLoS Genetics. 11, 10, 18 p., e1005520

    Research output: Contribution to journalArticle

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