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  1. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Turcot, V. , Lu, Y. , Highland, H. M. , Schurmann, C. , Justice, A. E. , Fine, R. S. , Bradfield, J. P. , Esko, T. , Giri, A. , Graff, M. , Guo, X. , Hendricks, A. E. , Karaderi, T. , Lempradl, A. , Locke, A. E. , Mahajan, A. , Marouli, E. , Sivapalaratnam, S. , Young, K. L. , Alfred, T. & 380 others Feitosa, M. F., Masca, N. G. D., Manning, A. K., Medina-Gomez, C., Mudgal, P., Ng, M. C. Y., Reiner, A. P., Vedantam, S., Willems, S. M., Winkler, T. W., Abecasis, G., Aben, K. K., Alam, D. S., Alharthi, S. E., Allison, M., Amouyel, P., Asselbergs, F. W., Auer, P. L., Balkau, B., Bang, L. E., Barroso, I., Bastarache, L., Benn, M., Bergmann, S., Bielak, L. F., Blüher, M., Boehnke, M., Boeing, H., Boerwinkle, E., Böger, C. A., Bork-Jensen, J., Bots, M. L., Bottinger, E. P., Bowden, D. W., Brandslund, I., Breen, G., Brilliant, M. H., Broer, L., Brumat, M., Burt, A. A., Butterworth, A. S., Campbell, P. T., Cappellani, S., Carey, D. J., Catamo, E., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Chen, Y. D. I., Chowdhury, R., Christensen, C., Chu, A. Y., Cocca, M., Collins, F. S., Cook, J. P., Corley, J., Corominas Galbany, J., Cox, A. J., Crosslin, D. S., Cuellar-Partida, G., D'Eustacchio, A., Danesh, J., Davies, G., Bakker, P. I. W., Groot, M. C. H., Mutsert, R., Deary, I. J., Dedoussis, G., Demerath, E. W., Heijer, M., Hollander, A. I., Ruijter, H. M., Dennis, J. G., Denny, J. C., Angelantonio, E., Drenos, F., Du, M., Dubé, M. P., Dunning, A. M., Easton, D. F., Edwards, T. L., Ellinghaus, D., Ellinor, P. T., Elliott, P., Evangelou, E., Farmaki, A. E., Farooqi, I. S., Faul, J. D., Fauser, S., Feng, S., Ferrannini, E., Ferrieres, J., Florez, J. C., Ford, I., Fornage, M., Franco, O. H., Franke, A., Franks, P. W., Friedrich, N., Frikke-Schmidt, R., Galesloot, T. E., Gan, W., Gandin, I., Gasparini, P., Gibson, J., Giedraitis, V., Gjesing, A. P., Gordon-Larsen, P., Gorski, M., Grabe, H. J., Grant, S. F. A., Grarup, N., Griffiths, H. L., Grove, M. L., Gudnason, V., Gustafsson, S., Haessler, J., Hakonarson, H., Hammerschlag, A. R., Hansen, T., Harris, K. M., Harris, T. B., Hattersley, A. T., Have, C. T., Hayward, C., He, L., Heard-Costa, N. L., Heath, A. C., Heid, I. M., Helgeland, Ø., Hernesniemi, J., Hewitt, A. W., Holmen, O. L., Hovingh, G. K., Howson, J. M. M., Hu, Y., Huang, P. L., Huffman, J. E., Ikram, M. A., Ingelsson, E., Jackson, A. U., Jansson, J. H., Jarvik, G. P., Jensen, G. B., Jia, Y., Johansson, S., Jørgensen, M. E., Jørgensen, T., Jukema, J. W., Kahali, B., Kahn, R. S., Kähönen, M., Kamstrup, P. R., Kanoni, S., Kaprio, J., Karaleftheri, M., Kardia, S. L. R., Karpe, F., Kathiresan, S., Kee, F., Kiemeney, L. A., Kim, E., Kitajima, H., Komulainen, P., Kooner, J. S., Kooperberg, C., Korhonen, T., Kovacs, P., Kuivaniemi, H., Kutalik, Z., Kuulasmaa, K., Kuusisto, J., Laakso, M., Lakka, T. A., Lamparter, D., Lange, E. M., Lange, L. A., Langenberg, C., Larson, E. B., Lee, N. R., Lehtimäki, T., Lewis, C. E., Li, H., Li, J., Li-Gao, R., Lin, H., Lin, K. H., Lin, L. A., Lin, X., Lind, L., Lindström, J., Linneberg, A., Liu, C. T., Liu, D. J., Liu, Y., Lo, K. S., Lophatananon, A., Lotery, A. J., Loukola, A., Luan, J. A., Lubitz, S. A., Lyytikäinen, L. P., Männistö, S., Marenne, G., Mazul, A. L., McCarthy, M. I., McKean-Cowdin, R., Medland, S. E., Meidtner, K., Milani, L., Mistry, V., Mitchell, P., Mohlke, K. L., Moilanen, L., Moitry, M., Montgomery, G. W., Mook-Kanamori, D. O., Moore, C., Mori, T. A., Morris, A. P., Morris, A. P., Müller-Nurasyid, M., Munroe, P. B., Nalls, M. A., Narisu, N., Nelson, C. P., Neville, M., Nielsen, S. F., Nikus, K., Njølstad, P. R., Nordestgaard, B. G., Nyholt, D. R., O'Connel, J. R., O'Donoghue, M. L., Olde Loohuis, L. M., Ophoff, R. A., Owen, K. R., Packard, C. J., Padmanabhan, S., Palmer, C. N. A., Palmer, N. D., Pasterkamp, G., Patel, A. P., Pattie, A., Pedersen, O., Peissig, P. L., Peloso, G. M., Pennell, C. E., Perola, M., Perry, J. A., Perry, J. R. B., Pers, T. H., Person, T. N., Peters, A., Petersen, E. R. B., Peyser, P. A., Pirie, A., Polasek, O., Polderman, T. J., Puolijoki, H., Raitakari, O. T., Rasheed, A., Rauramaa, R., Reilly, D. F., Renström, F., Rheinberger, M., Ridker, P. M., Rioux, J. D., Rivas, M. A., Roberts, D. J., Robertson, N. R., Robino, A., Rolandsson, O., Rudan, I., Ruth, K. S., Saleheen, D., Salomaa, V., Samani, N. J., Sapkota, Y., Sattar, N., Schoen, R. E., Schreiner, P. J., Schulze, M. B., Scott, R. A., Segura-Lepe, M. P., Shah, S. H., Sheu, W. H. H., Sim, X., Slater, A. J., Small, K. S., Smith, A. V., Southam, L., Spector, T. D., Speliotes, E. K., Starr, J. M., Stefansson, K., Steinthorsdottir, V., Stirrups, K. E., Strauch, K., Stringham, H. M., Stumvoll, M., Sun, L., Surendran, P., Swift, A. J., Tada, H., Tansey, K. E., Tardif, J. C., Taylor, K. D., Teumer, A., Thompson, D. J., Thorleifsson, G., Thorsteinsdottir, U., Thuesen, B. H., Tönjes, A., Tromp, G., Trompet, S., Tsafantakis, E., Tuomilehto, J., Tybjaerg-Hansen, A., Tyrer, J. P., Uher, R., Uitterlinden, A. G., Uusitupa, M., Laan, S. W., Duijn, C. M., Leeuwen, N., Van Setten, J., Vanhala, M., Varbo, A., Varga, T. V., Varma, R., Velez Edwards, D. R., Vermeulen, S. H., Veronesi, G., Vestergaard, H., Vitart, V., Vogt, T. F., Völker, U., Vuckovic, D., Wagenknecht, L. E., Walker, M., Wallentin, L., Wang, F., Wang, C. A., Wang, S., Wang, Y., Ware, E. B., Wareham, N. J., Warren, H. R., Waterworth, D. M., Wessel, J., White, H. D., Willer, C. J., Wilson, J. G., Witte, D. R., Wood, A. R., Wu, Y., Yaghootkar, H., Yao, J., Yao, P., Yerges-Armstrong, L. M., Young, R., Zeggini, E., Zhan, X., Zhang, W., Zhao, J. H., Zhao, W., Zhou, W., Zondervan, K. T., Rotter, J. I., Pospisilik, J. A., Rivadeneira, F., Borecki, I. B., Deloukas, P., Frayling, T. M., Lettre, G., North, K. E., Lindgren, C. M., Hirschhorn, J. N. & Loos, R. J. F. 1 Jan 2018 In : Nature Genetics. 50, 1, p. 26-35 10 p.

    Research output: Contribution to journalArticle

  2. Differential Distribution of Retinal Ca2+/Calmodulin-Dependent Kinase II (CaMKII) Isoforms Indicates CaMKII-β and -δ as Specific Elements of Electrical Synapses Made of Connexin36 (Cx36)

    Tetenborg, S., Yadav, S. C., Hormuzdi, S. G., Monyer, H., Janssen-Bienhold, U. & Dedek, K. 19 Dec 2017 In : Frontiers in Molecular Neuroscience. 10, 15 p., 425

    Research output: Contribution to journalArticle

  3. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein-coupled receptors

    Alexander, S. P. H., Christopoulos, A., Davenport, A. P., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174, Suppl. 1, p. S17-S129 113 p.

    Research output: Contribution to journalArticle

  4. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Voltage-gated ion channels

    Alexander, S. P. H., Striessnig, J., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S160-S194 35 p.

    Research output: Contribution to journalArticle

  5. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Other ion channels

    Alexander, S. P. H., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S195-S207 13 p.

    Research output: Contribution to journalArticle

  6. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Ligand-gated ion channels

    Alexander, S. P. H., Peters, J. A., Kelly, E., Marrion, N. V., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S130-S159 30 p.

    Research output: Contribution to journalArticle

  7. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Catalytic receptors

    Alexander, S. P. H., Fabbro, D., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S225-S271 47 p.

    Research output: Contribution to journalArticle

  8. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview

    Alexander, S. P. H., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Buneman, O. P., Cidlowski, J. A., Christopoulos, A., Davenport, A. P., Fabbro, D., Spedding, M., Striessnig, J., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S1-S16 16 p.

    Research output: Contribution to journalArticle

  9. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes

    Alexander, S. P. H., Fabbro, D., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S272-S359 88 p.

    Research output: Contribution to journalArticle

  10. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Nuclear hormone receptors

    Alexander, S. P. H., Cidlowski, J. A., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S208-S224 17 p.

    Research output: Contribution to journalArticle

  11. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters

    Alexander, S. P. H., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S360-S446 87 p.

    Research output: Contribution to journalArticle

  12. Editorial: Role of protein-protein interactions in metabolism: Genetics, structure, function

    Pandey, A. V., Henderson, C. J., Ishii, Y., Kranendonk, M., Backes, W. L. & Zanger, U. M. 27 Nov 2017 In : Frontiers in Pharmacology. 8, p. 1-3 3 p., 881

    Research output: Contribution to journalEditorial

  13. Interim heterogeneity changes measured using entropy texture features on T2- weighted MRI at 3.0 T predict pathological response to neoadjuvant chemotherapy in primary breast cancer

    Henderson, S., Purdie, C., Michie, C., Evans, A., Lerski, R., Johnston, M., Vinnicombe, S. & Thompson, A. M. Nov 2017 In : European Radiology. 27, 11, p. 4602-4611 10 p.

    Research output: Contribution to journalArticle

  14. New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

    Kraja, A. T. , Cook, J. P. , Warren, H. R. , Surendran, P. , Liu, C. , Evangelou, E. , Manning, A. K. , Grarup, N. , Drenos, F. , Sim, X. , Smith, A. V. , Amin, N. , Blakemore, A. I. F. , Bork-Jensen, J. , Brandslund, I. , Farmaki, A-E. , Fava, C. , Ferreira, T. , Herzig, K-H. , Giri, A. & 124 others Giulianini, F., Grove, M. L., Guo, X., Harris, S. E., Have, C. T., Havulinna, A. S., Zhang, H., Jørgensen, M. E., Käräjämäki, A. M., Kooperberg, C., Linneberg, A., Little, L., Liu, Y., Bonnycastle, L. L., Lu, Y., Mägi, R., Mahajan, A., Malerba, G., Marioni, R. E., Mei, H., Menni, C., Morrison, A. C., Padmanabhan, S., Palmas, W., Poveda, A., Rauramaa, R., Rayner, N. W., Riaz, M., Rice, K., Richard, M. A., Smith, J. A., Southam, L., Stančáková, A., Stirrups, K. E., Tragante, V., Tuomi, T., Tzoulaki, I., Varga, T. V., Weiss, S., Yiorkas, A. M., Young, R., Zhang, W., Barnes, M. R., Cabrera, C. P., Gao, H., Boehnke, M., Boerwinkle, E., Chambers, J. C., Connell, J. M., Christensen, C. K., de Boer, R. A., Deary, I. J., Dedoussis, G., Deloukas, P., Dominiczak, A. F., Dörr, M., Joehanes, R., Edwards, T. L., Esko, T., Fornage, M., Franceschini, N., Franks, P. W., Gambaro, G., Groop, L. C., Hallmans, G., Hansen, T., Hayward, C., Heikki, O., Ingelsson, E., Tuomilehto, J., Jarvelin, M-R., Kardia, S. L. R., Karpe, F., Kooner, J. S., Lakka, T. A., Langenberg, C., Lind, L., Loos, R. J. F., Laakso, M., McCarthy, M. I., Melander, O., Mohlke, K. L., Morris, A. P., Palmer, C. N. A., Pedersen, O., Polasek, O., Poulter, N. R., Province, M. A., Psaty, B. M., Ridker, P. M., Rotter, J. I., Rudan, I., Salomaa, V., Samani, N. J., Sever, P. J., Skaaby, T., Stafford, J. M., Starr, J. M., van der Harst, P., van der Meer, P., van Duijn, C. M., Vergnaud, A-C., Gudnason, V., Wareham, N. J., Wilson, J. G., Willer, C. J., Witte, D. R., Zeggini, E., Saleheen, D., Butterworth, A. S., Danesh, J., Asselbergs, F. W., Wain, L. V., Ehret, G. B., Chasman, D. I., Caulfield, M. J., Elliott, P., Lindgren, C. M., Levy, D., Newton-Cheh, C., Munroe, P. B., Howson, J. M. M., The Understanding Society Scientific Group & behalf of the CHARGE EXOME BP, CHD Exome+, Exome BP, GoT2D:T2DGenes Consortia, The UK Biobank Cardio-Metabolic Traits Consortium Blood Pressure Working Group 13 Oct 2017 In : Circulation: Cardiovascular Genetics. 10, 5, e001778

    Research output: Contribution to journalArticle

  15. Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk

    Brænne, I. , Zeng, L. , Willenborg, C. , Tragante, V. , Kessler, T. , Willer, C. J. , Laakso, M. , Wallentin, L. , Franks, P. W. , Salomaa, V. , Dehghan, A. , Meitinger, T. , Samani, N. J. , Asselbergs, F. W. , Erdmann, J. , Schunkert, H. , Deloukas, P. , Kanoni, S. , Willenborg, C. , Farrall, M. & 198 others Assimes, T. L., Thompson, J. R., Ingelsson, E., Saleheen, D., Erdmann, J., Goldstein, B. A., Stirrups, K., König, I. R., Cazier, J-B., Johansson, Å., Hall, A. S., Lee, J-Y., Willer, C. J., Chambers, J. C., Esko, T., Folkersen, L., Goel, A., Grundberg, E., Havulinna, A. S., Ho, W. K., Hopewell, J. C., Eriksson, N., Kleber, M. E., Kristiansson, K., Lundmark, P., Lyytikäinen, L-P., Rafelt, S., Shun, D., Strawbridge, R. J., Thorleifsson, G., Tikkanen, E., Van Zuydam, N., Voight, B. F., Waite, L. L., Zhang, W., Zieg, A., Absher, D. M., Altshuler, D., Balmforth, A. J., Barroso, I., Braund, P. S., Burgdorf, C., Claudi-Boehm, S., Cox, D. N., Dimitriou, M., Do, R., Doney, A. S. F., El-Mokhtari, N. E., Eriksson, P., Fischer, K., Fontanillas, P., Franco-Cereceda, A., Gigante, B., Groop, L. C., Gustafsson, S., Hager, J., Hallmans, G., Han, B-G., Ehunt, S., Kang, H. M., Illig, T., Kessler, T., Knowles, J. W., Kolovou, G., Kuusisto, J., Langenberg, C., Langford, C. F., Leander, K., Lokki, M-L., Lundmark, A., McCarthy, M. I., Meisinger, C., Melander, O., Mihailov, E., Maouche, S., Morris, A. D., Müller-Nurasyid, M., Nikus, K., Peden, J. F., Rayner, N. W., Rasheed, A., Rosinger, S., Rubin, D., Rumpf, M. P., Schäfer, A., Sivananthan, M., Song, C., Stewart, A. F. R., Tan, S-T., Thorgeirsson, G., van der Schoot, C. E., Wagner, P. J., Wells, G. A., Wild, P. S., Yang, T-P., Amouyel, P., Arveiler, D., Basart, H., Boehnke, M., Boerwinkle, E., Brambilla, P., Cambien, F., Cupples, L. A., de Faire, U., Dehghan, A., Diemert, P., Epstein, S. E., Evans, A., Ferrario, M. M., Ferrières, J., Gauguier, D., Go, A. S., Goodall, A. H., Gudnason, V., Hazen, S. L., Holm, H., Iribarren, C., Jang, Y., Kähönen, M., Kee, F., Kim, H. S., Klopp, N., Koenig, W., Kratzer, W., Kuulasmaa, K., Laakso, M., Laaksonen, R., Lee, J-Y., Lind, L., Ouwehand, W. H., Parish, S., Park, J. E., Pedersen, N. L., Peters, A., Quertermous, T., Rader, D. J., Salomaa, V., Schadt, E. E., Shah, S. H., Sinisalo, J., Stark, K., Stefansson, K., Trégouët, D-A., Virtamo, J., Wallentin, L., Wareham, N. J., Zimmermann, M. E., Nieminen, M. S., Hengsten, C., Sandhu, M. S., Pastinen, T., Syvänen, A-C., Hovingh, G. K., Dedoussis, G., Franks, P. W., Lehtimäki, T., Metspalu, A., Zalloua, P. A., Siegbahn, A., Schreiber, S., Ripatti, S., Blankenberg, S. S., Perola, M., Clarke, R., Oboehm, B., O’Donnell, C., Reilly, M. P., März, W., Collins, R., Kathiresan, S., Hamsten, A., Kooner, J. S., Thorsteinsdottir, U., Danesh, J., Palmer, C. N. A., Roberts, R., Watkins, H., Schunkert, H., Samani, N. J., Assimes, T. L., Boerwinkle, E., Erdmann, J., Hall, A. S., Hengstenberg, C., Kathiresan, S., König, I. R., Laaksonen, R., McPherson, R., Reilly, M. P., Samani, N. J., Schunkert, H., Thompson, J. R., Thorsteinsdottir, U., Ziegler, A., CARDIoGRAM Consortium, CARDIoGRAMplusC4D Consortium, MuTHER Consortium & Wellcome Trust Case Control Consortium 22 Aug 2017 In : PLoS ONE. 12, 8, p. 1-19 19 p., e0182999

    Research output: Contribution to journalArticle

  16. Alcohol and disadvantaged men: a feasibility trial of an intervention delivered by mobile phone

    Crombie, I. K., Irvine, L., Falconer, D. W., Williams, B., Ricketts, I. W., Jones, C., Humphris, G. M., Norrie, J., Slane, P. & Rice, P. 5 Jul 2017 In : Drug and Alcohol Review. 36, 4, p. 468-476 9 p.

    Research output: Contribution to journalArticle

  17. Erratum to: Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers

    Nair, A., McKinlay, L., Williamson, P., Short, P., Burns, P. & Lipworth, B. J. Jun 2017 In : European Journal of Clinical Pharmacology. 73, 6, p. 793-793 1 p.

    Research output: Contribution to journalArticle

  18. Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates

    Bartolome, F., Esteras, N., Martin-Requero, A., Boutoleau-Bretonniere, C., Vercelletto, M., Gabelle, A., Le Ber, I., Honda, T., Dinkova-Kostova, A. T., Hardy, J., Carro, E. & Abramov, A. Y. 10 May 2017 In : Scientific Reports. 7, p. 1-14 14 p., 1666

    Research output: Contribution to journalArticle

  19. Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews

    Geneen, L. J., Moore, R. A., Clarke, C., Martin, D., Colvin, L. A. & Smith, B. H. 24 Apr 2017 In : Cochrane Database of Systematic Reviews. 2017, 4, p. 1-75 75 p., CD011279

    Research output: Contribution to journalReview article

  20. 'Thinking that somebody's going to delay [a tonsillectomy] for one to two years is quite horrifying really': a qualitative feasibility study for the NAtional Trial of Tonsillectomy IN Adults (NATTINA Part 2)

    McSweeney, L. A., O'Hara, J. T., Rousseau, N. S., Stocken, D. D., Sullivan, F., Vale, L., Wilkes, S., Wilson, J. A. & Haighton, C. A. 23 Apr 2017 In : Clinical Otolaryngology. 42, 3, p. 578-583 6 p.

    Research output: Contribution to journalArticle

  21. Better guidelines for better care: accounting for multimorbidity in clinical guidelines – structured examination of exemplar guidelines and health economic modelling

    Guthrie, B., Thompson, A., Dumbreck, S., Flynn, A., Alderson, P., Nairn, M., Treweek, S. & Payne, K. Apr 2017 In : Health Services and Delivery Research. 5, 16, p. 1-179 179 p.

    Research output: Contribution to journalArticle

  22. Progress in identifying epigenetic mechanisms of xenobiotic-induced non-genotoxic carcinogenesis

    Terranova, R., Vitobello, A., Del Rio Espinola, A., Wolf, C. R., Schwarz, M., Thomson, J. M., Meehan, R. & Moggs, J. G. Apr 2017 In : Current Opinion in Toxicology. 3, p. 62-70 9 p.

    Research output: Contribution to journalReview article

  23. Defining drug response for stratified medicine

    Lonergan, M., Senn, S. J., McNamee, C., Daly, A. K., Sutton, R., Hattersley, A., Pearson, E. & Pirmohamed, M. Jan 2017 In : Drug Discovery Today. 22, 1, p. 173-179 7 p.

    Research output: Contribution to journalReview article

  24. The effect of dietary intervention on the metabolic and behavioural impairments generated by short term high fat feeding in the rat

    McNeilly, A. D., Gao, A., Hill, A. Y., Gomersall, T., Balfour, D. J. K., Sutherland, C. & Stewart, C. A. 1 Dec 2016 In : Physiology & Behavior. 167, p. 100-109 10 p.

    Research output: Contribution to journalArticle

  25. Fatal attractions? Correlations of CXCL12–CXCR4–CXCR7 expression with disease progression in melanoma and Kaposi sarcoma

    Spender, L. C. & Inman, G. J. Dec 2016 In : British Journal of Dermatology. 175, 6, p. 1140-1141 2 p.

    Research output: Contribution to journalComment/debate

  26. Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

    Postmus, I. , Warren, H. R. , Trompet, S. , Arsenault, B. J. , Avery, C. L. , Bis, J. C. , Chasman, D. I. , de Keyser, C. E. , Deshmukh, H. A. , Evans, D. S. , Feng, Q. , Li, X. , Smit, R. A. J. , Smith, A. V. , Sun, F. , Taylor, K. D. , Arnold, A. M. , Barnes, M. R. , Barratt, B. J. , Betteridge, J. & 68 others Boekholdt, S. M., Boerwinkle, E., Buckley, B. M., Chen, Y-D. I., de Craen, A. J. M., Cummings, S. R., Denny, J. C., Dubé, M. P., Durrington, P. N., Eiriksdottir, G., Ford, I., Guo, X., Harris, T. B., Heckbert, S. R., Hofman, A., Hovingh, G. K., Kastelein, J. J. P., Launer, L. J., Liu, C-T., Liu, Y., Lumley, T., McKeigue, P. M., Munroe, P. B., Neil, A., Nickerson, D. A., Nyberg, F., O'Brien, E., O'Donnell, C. J., Post, W., Poulter, N., Vasan, R. S., Rice, K., Rich, S. S., Rivadeneira, F., Sattar, N., Sever, P., Shaw-Hawkins, S., Shields, D. C., Slagboom, P. E., Smith, N. L., Smith, J. D., Sotoodehnia, N., Stanton, A., Stott, D. J., Stricker, B. H., Stürmer, T., Uitterlinden, A. G., Wei, W-Q., Westendorp, R. G. J., Whitsel, E. A., Wiggins, K. L., Wilke, R. A., Ballantyne, C. M., Colhoun, H. M., Cupples, L. A., Franco, O. H., Gudnason, V., Hitman, G., Palmer, C. N. A., Psaty, B. M., Ridker, P. M., Stafford, J. M., Stein, C. M., Tardif, J-C., Caulfield, M. J., Jukema, J. W., Rotter, J. I. & Krauss, R. M. Dec 2016 In : Journal of Medical Genetics. 53, 12, p. 835-845 11 p.

    Research output: Contribution to journalArticle

  27. Regulation of the CNC-bZIP transcription factor Nrf2 by Keap1 and the axis between GSK-3 and β-TrCP

    Hayes, J. D., Ebisine, K., Sharma, R. S., Chowdhry, S., Dinkova-Kostova, A. T. & Sutherland, C. Dec 2016 In : Current Opinion in Toxicology. 1, p. 92-103 12 p.

    Research output: Contribution to journalReview article

  28. The multifaceted role of Nrf2 in mitochondrial function

    Holmström, K. M., Kostov, R. V. & Dinkova-Kostova, A. T. Dec 2016 In : Current Opinion in Toxicology. 1, p. 80-91 12 p.

    Research output: Contribution to journalReview article

  29. Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

    Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J. 20 Nov 2016 New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January, p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  30. How can we optimise inhaled beta2 agonist dose as 'reliever' medicine for wheezy pre-school children?: Study protocol for a randomised controlled trial

    Mukhopadhyay, S., Seddon, P., Earl, G., Wileman, E., Symes, L., Olden, C., Alberti, C., Bremner, S., Lansley, A., Palmer, C. N. A. & Beydon, N. 11 Nov 2016 In : Trials. 17, p. 1-9 9 p., 541

    Research output: Contribution to journalArticle

  31. Microbubble–liposome conjugate: Payload evaluation of potential theranostic vehicle

    Malik, R., Pancholi, K. & Melzer, A. 3 Oct 2016 In : Nanobiomedicine. 3, p. 1-8 8 p.

    Research output: Contribution to journalArticle

  32. The ClearPET/XPAD prototype: Development of a simultaneous PET/CT scanner for mice

    Hamonet, M., Dupont, M., Fabiani, T., Cassol, F., Boursier, Y., Bonissent, A., Debarbieux, F., Pottier, G., Bidaut, L. & Morel, C. 3 Oct 2016 2015 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2015. Institute of Electrical and Electronics Engineers Inc., p. 1-3 3 p. 7582074

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  33. Nrf2-mediated neuroprotection response to recurrent hypoglycemia is insufficient to prevent cognitive impairment in a rodent model of type 1 diabetes

    McNeilly, A. D., Gallagher, J. R., Dinkova-Kostova, A. T., Hayes, J. D., Sharkey, J., Ashford, M. L. J. & McCrimmon, R. J. 1 Oct 2016 In : Diabetes. 65, 10, p. 3151-3160 10 p.

    Research output: Contribution to journalArticle

  34. Trends in type 2 diabetes incidence and mortality in Scotland between 2004 and 2013

    Read, S. H., Kerssens, J. J., McAllister, D. A., Colhoun, H. M., Fischbacher, C. M., Lindsay, R. S., McCrimmon, R. J., McKnight, J. A., Petrie, J. R., Sattar, N., Wild, S. H. & On behalf of the Scottish Diabetes Research Network Epidemiology Group Oct 2016 In : Diabetologia. 59, 10, p. 2106-2113 8 p.

    Research output: Contribution to journalArticle

  35. Childhood obesity in relation to poor asthma control and exacerbation: a meta-analysis

    Ahmadizar, F., Vijverberg, S. J. H., Arets, H. G. M., de Boer, A., Lang, J. E., Kattan, M., Palmer, C. N. A., Mukhopadhyay, S., Turner, S. & Maitland-van der Zee, A. H. 30 Sep 2016 In : European Respiratory Journal. 48, 4, p. 1063-1073 11 p.

    Research output: Contribution to journalArticle

  36. Tumour suppressor gene (CDKNA2) status on chromosome 9p in resected renal tissue improves prognosis of localised kidney cancer

    El-Mokadem, I., Kidd, T., Pratt, N., Fleming, S. & Nabi, G. 22 Sep 2016 In : Oncotarget. 7, 45, p. 1-10 10 p.

    Research output: Contribution to journalArticle

  37. Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

    Gonçalves, I. , Edsfeldt, A. , Colhoun, H. M. , Shore, A. C. , Palombo, C. , Natali, A. , Fredrikson, G. N. , Björkbacka, H. , Wigren, M. , Bengtsson, E. , Östling, G. , Aizawa, K. , Casanova, F. , Persson, M. , Gooding, K. , Gates, P. , Khan, F. , Looker, H. C. , Adams, F. , Belch, J. & 7 others Pinnola, S., Venturi, E., Kozakova, M., Gan, L-M., Schnecke, V., Nilsson, J. & on behalf of the SUMMIT consortium 5 Sep 2016 In : BMC Cardiovascular Disorders. 16, p. 1-10 10 p., 171

    Research output: Contribution to journalArticle

  38. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

    Cameron, A. R., Morrison, V., Levin, D., Mohan, M., Forteath, C., Beall, C., McNeilly, A. D., Balfour, D. J. K., Savinko, T., Wong, A. K. F., Viollet, B., Sakamoto, K., Fagerholm, S. C., Foretz, M., Lang, C. C. & Rena, G. 19 Aug 2016 In : Circulation Research. 119, 5, p. 652-665 14 p.

    Research output: Contribution to journalArticle

  39. tRNA methyltransferase homologue gene TRMT10A mutation in young adult-onset diabetes with intellectual disability, microcephaly and epilepsy

    Yew, T. W., McCreight, L., Colclough, K., Ellard, S. & Pearson, E. R. 17 Aug 2016 In : Diabetic Medicine. 33, 9, p. e21-e25 5 p.

    Research output: Contribution to journalArticle

  40. Focal PPK secondary to a novel KRT6C mutation (Pachyonychia congenita-K6c)

    Wee, J. S., Smith, F. J. D., Wilson, N. J. & O'Toole, E. A. 12 Aug 2016 In : Journal of the European Academy of Dermatology and Venereology. 30, 8, p. 1415-1416 2 p.

    Research output: Contribution to journalLetter

  41. Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

    Daniels, M. J. D. , Rivers-Auty, J. , Schilling, T. , Spencer, N. G. , Watremez, W. , Fasolino, V. , Booth, S. J. , White, C. S. , Baldwin, A. G. , Freeman, S. , Wong, R. , Latta, C. , Yu, S. , Jackson, J. , Fischer, N. , Koziel, V. , Pillot, T. , Bagnall, J. , Allan, S. M. , Paszek, P. & 5 others Galea, J., Harte, M. K., Eder, C., Lawrence, C. B. & Brough, D. 11 Aug 2016 In : Nature Communications. 7, p. 1-10 10 p., 12504

    Research output: Contribution to journalArticle

  42. Reports of Perceived Adverse Events of Stimulant Medication on Cognition, Motivation, and Mood: Qualitative Investigation and the Generation of Items for the Medication and Cognition Rating Scale

    Kovshoff, H., Banaschewski, T., Buitelaar, J. K., Carucci, S., Coghill, D., Danckaerts, M., Dittmann, R. W., Falissard, B., Grimshaw, D. G., Hollis, C., Inglis, S., Konrad, K., Liddle, E., McCarthy, S., Nagy, P., Thompson, M., Wong, I. C. K., Zuddas, A. & Sonuga-Barke, E. J. S. 1 Aug 2016 In : Journal of Child and Adolescent Psychopharmacology. 26, 6, p. 537-547 11 p.

    Research output: Contribution to journalArticle

  43. Acute risk factors in fatal opioid overdoses as a result of hypoxia and cardiotoxicity. A systematic review and critical appraisal

    Baldacchino, A., Tolomeo, S., Khan, F., Humphris, G. & Carrà, G. Aug 2016 In : Heroin Addiction and Related Clinical Problems. 18, 4, p. 33-42 10 p.

    Research output: Contribution to journalReview article

  44. CREBBP mutation in human cutaneous squamous cell carcinoma

    Watt, S. A., Purdie, K. J., den Breems, N. Y., Dimon, M., Tucker, S., Arron, S. T., Mchugh, A., Xue, D. J., Dayal, J. H. S., Harwood, C. A., Leigh, I. M., Proby, C. M. & South, A. P. Aug 2016 In : Experimental Dermatology. 25, 8, p. 650-651 2 p.

    Research output: Contribution to journalLetter

  45. Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells

    Leitch, C. S., Natafji, E., Yu, C., Abdul-Ghaffar, S., Madarasingha, N., Venables, Z. C., Chu, R., Fitch, P. M., Muinonen-Martin, A. J., Campbell, L. E., McLean, W. H. I., Schwarze, J., Howie, S. E. M. & Weller, R. B. Aug 2016 In : Journal of Allergy and Clinical Immunology. 138, 2, p. 482-490.e7 16 p.

    Research output: Contribution to journalArticle

  46. Intraoperative Ultrasound-Guided Resection of Gliomas: A Meta-Analysis and Review of the Literature

    Mahboob, S., McPhillips, R., Qiu, Z., Jiang, Y., Meggs, C., Schiavone, G., Button, T., Desmulliez, M., Demore, C., Cochran, S. & Eljamel, S. Aug 2016 In : World Neurosurgery. 92, p. 255-263 9 p.

    Research output: Contribution to journalReview article

  47. Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug

    Cameron, A., Logie, L., Patel, K., Bacon, S., Forteath, C., Harthill, J., Roberts, A., Sutherland, C., Stewart, D., Viollet, B., Sakamoto, K., McDougall, G., Foretz, M. & Rena, G. Aug 2016 In : Biochimica et Biophysica Acta. Molecular Basis of Disease. 1862, 8, p. 1412-1422 11 p.

    Research output: Contribution to journalArticle

  48. Rhodiola rosea L.: from golden root to green cell factories

    Marchev, A. S., Dinkova-Kostova, A. T., György, Z., Mirmazloum, I., Aneva, I. Y. & Georgiev, M. I. Aug 2016 In : Phytochemistry Reviews. 15, 4, p. 515-536 22 p.

    Research output: Contribution to journalArticle

  49. SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models

    Quinti, L. , Casale, M. , Moniot, S. , Pais, T. F. , Van Kanegan, M. J. , Kaltenbach, L. S. , Pallos, J. , Lim, R. G. , Naidu, S. D. , Runne, H. , Meisel, L. , Rauf, N. A. , Leyfer, D. , Maxwell, M. M. , Saiah, E. , Landers, J. E. , Luthi-Carter, R. , Abagyan, R. , Dinkova-Kostova, A. T. , Steegborn, C. & 4 others Marsh, J. L., Lo, D. C., Thompson, L. M. & Kazantsev, A. G. 21 Jul 2016 In : Cell Chemical Biology. 23, 7, p. 849-861 13 p.

    Research output: Contribution to journalArticle

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