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  1. Suppression of the Deubiquitinating Enzyme USP5 Causes the Accumulation of Unanchored Polyubiquitin and the Activation of p53

    Dayal, S., Sparks, A., Jacob, J., Allende-Vega, N., Lane, D. & Saville, M. K. 20 Feb 2009 In : Journal of Biological Chemistry. 284, 8, p. 5030-5041 12 p.

    Research output: Contribution to journalArticle

  2. Autoimmune pancytopenia following combination chemotherapy for chronic lymphocytic leukaemia

    MacCallum, S., Groves, M., Brass, D., Cunningham, J., Sales, M., Gelly, K. & Tauro, S. 2009 In : Journal of Clinical Pathology. 62, 5, p. 468-470 3 p.

    Research output: Contribution to journalArticle

  3. Characterization, chemical optimization and anti-tumour activity of a tubulin poison identified by a p53-based phenotypic screen

    Staples, O. D., Hollick, J. J., Campbell, J., Higgins, M., McCarthy, A. R., Appleyard, V., Murray, K. E., Baker, L., Thompson, A., Ronseaux, S., Slawin, A. M. Z., Lane, D. P., Westwood, N. J. & Lain, S. 1 Nov 2008 In : Cell Cycle. 7, 21, p. 3417-3427 11 p.

    Research output: Contribution to journalArticle

  4. Targeting a nucleolar SUMO protease for degradation: a mechanism by which ARF induces SUMO conjugation

    Xirodimas, D. P. & Lane, D. P. 1 Nov 2008 In : Cell Cycle. 7, 21, p. 3287-3288 2 p.

    Research output: Contribution to journalArticle

  5. Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita

    Leachman, S. A., Hickerson, R. P., Hull, P. R., Smith, F. J. D., Milstone, L. M., Lane, E. B., Bale, S. J., Roop, D. R., McLean, W. H. I. & Kaspar, R. L. Sep 2008 In : Journal of Dermatological Science. 51, 3, p. 151-157 7 p.

    Research output: Contribution to journalScientific review

  6. Unique and recurrent mutations in the filaggrin gene in Singaporean Chinese patients with ichthyosis vulgaris

    Chen, H., Ho, J. C. C., Sandilands, A., Chan, Y. C., Giam, Y. C., Evans, A. T., Lane, E. B. & McLean, W. H. I. Jul 2008 In : Journal of Investigative Dermatology. 128, 7, p. 1669-1675 7 p.

    Research output: Contribution to journalArticle

  7. Discovery, in vivo activity and mechanism of action of a small-molecule p53 activator

    Lain, S., Hollick, J. J., Campbell, J., Staples, O. D., Higgins, M., Aoubala, M., McCarthy, A., Appleyard, V., Murray, K. E., Baker, L., Thompson, A., Mathers, J., Holland, S. J., Stark, M. J. R., Pass, G., Woods, J., Lane, D. P. & Westwood, N. J. 6 May 2008 In : Cancer Cell. 13, 5, p. 454-463 10 p.

    Research output: Contribution to journalArticle

  8. Keratin K6c mutations cause focal keratoderma

    Wilson, N. J., Messenger, A. G., Leachmin, S. A., Lane, E. B., McLean, W. & Smith, F. J. Apr 2008 In : Journal of Investigative Dermatology. 128, p. S127-S127 1 p.Abstract 757

    Research output: Contribution to journalBook/Film/Article review

  9. p53 activating benzoyl urea and benzoyl thiourea compounds

    Lain, S., Lane, D., Stark, M. J. R., McCarthy, A. R., Hollick, J. J. & Westwood, N. J. 13 Mar 2008 WO2008029096

    Research output: Patent

  10. Broken bricks and cracked mortar - epidermal diseases resulting from genetic abnormalities

    Lane, E. B. & McLean, W. H. I. 1 Mar 2008 In : Drug Discovery Today: Disease Mechanisms. 5, 1

    Research output: Contribution to journalArticle

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