Molecular Medicine

Mechanical stress induces profound remodelling of keratin filaments and cell junctions in epidermolysis bullosa simplex keratinocytes

Russell, D., Andrews, P. D., James, J. & Lane, E. B. Oct-2004 In : Journal of Cell Science. 117, 22, p. 5233-5243, 11 p.

Research output: Contribution to journal › Article

Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity

Xirodimas, D. P., Saville, M. K., Bourdon, J. C., Hay, R. T. & Lane, D. P. 9-Jul-2004 In : Cell. 118, 1, p. 83-97, 15 p.

Research output: Contribution to journal › Article

Human keratin 8 mutations that disturb filament assembly observed in inflammatory bowel disease patients

Owens, D. W., Wilson, N. J., Hill, A. J. M., Rugg, E. L., Porter, R. M., Hutcheson, A. M., Quinlan, R. A., van Heel, D., Parkes, M., Jewell, D. P., Campbell, S. S., Ghosh, S., Satsangi, J. & Lane, E. B. Apr-2004 In : Journal of Cell Science. 117, 10, p. 1989-1999, 11 p.

Research output: Contribution to journal › Article

Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21^WAF1

Burch, L. R., Scott, M., Pohler, E., Meek, D. & Hupp, T. 12-Mar-2004 In : Journal of Molecular Biology. 337, 1, p. 115-128, 14 p.

Research output: Contribution to journal › Article

p14 arf promotes small ubiquitin-like modifier conjugation of Werners helicase

Woods, Y. L., Xirodimas, D. P., Prescott, A. R., Sparks, A., Lane, D. P. & Saville, M. K. 2004 In : Journal of Biological Chemistry. 279, 48, p. 50157-50166, 10 p.

Research output: Contribution to journal › Article

SEP53 and AG-2 may act as proto-oncogenes in Barrett's metaplasia

Dalziel, H. H., Pohler, E., Quayle, L., Cotton, J. P., Hupp, T. R. & Dillon, J. F. 2004 In : Gut. 53, S3, p. A35-A35

Research output: Contribution to journal › Meeting abstract

The Barrett's antigen anterior gradient-2 silences the p53 transcriptional response to DNA damage

Pohler, E., Craig, A. L., Cotton, J., Lawrie, L., Dillon, J. F., Ross, P., Kernohan, N. & Hupp, T. R. 2004 In : Molecular & Cellular Proteomics. 3, 6, p. 534-547, 14 p.

Research output: Contribution to journal › Article

Oligomerization of the human ARF tumor suppressor and its response to oxidative stress

Menendez, S., Khan, Z., Coomber, D., Lane, D., Higgins, M., Koufali, M. M. & Lain, S. May-2003 In : Journal of Biological Chemistry. 278, 21, p. 18720-18729, 10 p.

Research output: Contribution to journal › Article

Alteration of glutathione S-transferase levels in Barrett's metaplasia compared to normal oesophageal epithelium

Cobbe, S. C., Scobie, G. C., Pohler, E., Hayes, J. D., Kernohan, N. M. & Dillon, J. F. 2003 In : European Journal of Gastroenterology & Hepatology. 15, 1, p. 41-47, 7 p.

Research output: Contribution to journal › Article

Dysregulation of the major squamous cell stress responsive system in Barrett's metaplasia

Dalziel, H. H., Pohler, E., Craig, A. L., Kernohan, N., Hopwood, D., Dillon, J. F. & Hupp, T. R. 2003 In : Gut. 52, S1, p. A7-A7, 1 p.

Research output: Contribution to journal › Meeting abstract