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Molecular Medicine

  1. Gene expression profiling in pachyonychia congenita skin

    Cao, Y. A., Hickerson, R. P., Seegmiller, B. L., Grapov, D., Gross, M. M., Bessette, M. R., Phinney, B. S., Flores, M. A., Speaker, T. J., Vermeulen, A., Bravo, A. A., Bruckner, A. L., Milstone, L. M., Schwartz, M. E., Rice, R. H. & Kaspar, R. L. Mar 2015 In : Journal of Dermatological Science. 77, 3, p. 156-165 10 p.

    Research output: Contribution to journalArticle

  2. In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation

    Hegde, V., Hickerson, R. P., Nainamalai, S., Campbell, P. A., Smith, F. J. D., McLean, W. H. I. & Leslie Pedrioli, D. M. 28 Dec 2014 In : Journal of Controlled Release: Official Journal of the Controlled Release Society, and of the Japan Society of Drug Delivery System. 196, p. 355-362 8 p.

    Research output: Contribution to journalArticle

  3. Novel cyclic di-GMP effectors of the YajQ protein family control bacterial virulence

    An, S., Caly, D. L., McCarthy, Y., Murdoch, S. L., Ward, J., Febrer, M., Dow, J. M. & Ryan, R. P. 16 Oct 2014 In : PLoS Pathogens. 10, 10, 12 p.e1004429

    Research output: Contribution to journalArticle

  4. POU2F1 activity regulates HOXD10 and HOXD11 promoting a proliferative and invasive phenotype in Head and Neck cancer

    Sharpe, D. J., Orr, K. S., Moran, M., White, S. J., McQuaid, S., Lappin, T. R., Thompson, A. & James, J. A. 16 Sep 2014 In : Oncotarget. 5, 18, p. 8803-8815 13 p.

    Research output: Contribution to journalArticle

  5. New and recurrent AAGAB mutations in punctate palmoplantar keratoderma

    Pohler, E., Huber, M., Boonen, S. E., Zamiri, M., Gregersen, P. A., Sommerlund, M., Ramsing, M., Hohl, D., McLean, W. H. I. & Smith, F. J. Aug 2014 In : British Journal of Dermatology. 171, 2, p. 433-436

    Research output: Contribution to journalLetter

  6. Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung

    McMillan, S. J., Sharma, R. S., Richards, H. E., Hegde, V. & Crocker, P. R. 18 Jul 2014 In : Journal of Biological Chemistry. 289, 29, p. 20370-20376 7 p.

    Research output: Contribution to journalArticle

  7. The PAS domain-containing histidine kinase RpfS is a second sensor for the diffusible signal factor of Xanthomonas campestris

    An, S-Q., Allan, J. H., McCarthy, Y., Febrer, M., Dow, J. M. & Ryan, R. P. May 2014 In : Molecular Microbiology. 92, 3, p. 586-597 12 p.

    Research output: Contribution to journalArticle

  8. Peptide aptamers define distinct EB1- and EB3-binding motifs and interfere with microtubule dynamics

    Lesniewska, K., Warbrick, E. & Ohkura, H. 1 Apr 2014 In : Molecular Biology of the Cell. 25, 7, p. 1025-1036 12 p.

    Research output: Contribution to journalArticle

  9. Atopic dermatitis and disease severity are the main risk factors for food sensitization in exclusively breastfed infants

    Flohr, C., Perkin, M., Logan, K., Marrs, T., Radulovic, S., Campbell, L. E., Maccallum, S. F., McLean, W. H. I. & Lack, G. Feb 2014 In : Journal of Investigative Dermatology. 134, 2, p. 345-350 6 p.

    Research output: Contribution to journalArticle

  10. How detection of epigenetic alterations of blood-borne DNA could improve melanoma diagnosis

    Hatzimichael, E., Syed, N., Lo Nigro, C., Rao, B. & Crook, T. 2014 In : Expert Review of Molecular Diagnostics. 14, 6, p. 639-642 4 p.

    Research output: Contribution to journalArticle

  11. Heterozygous mutations in AAGAB cause type 1 punctate palmoplantar keratoderma with evidence for increased growth factor signaling

    Pohler, E., Zamiri, M., Harkins, C., Salas-Alanis, J. C., Perkins, W., Smith, F. J. D., McLean, W. H. I. & Brown, S. J. Dec 2013 In : Journal of Investigative Dermatology. 133, 12, p. 2805-2808 4 p.

    Research output: Contribution to journalLetter

  12. A cyclic GMP-dependent signalling pathway regulates bacterial phytopathogenesis

    An, S-Q., Chin, K-H., Febrer, M., McCarthy, Y., Yang, J-G., Liu, C-L., Swarbreck, D., Rogers, J., Dow, J. M., Chou, S-H. & Ryan, R. P. 11 Sep 2013 In : EMBO Journal. 32, 18, p. 2430-2438

    Research output: Contribution to journalArticle

  13. The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage

    Nicol, S. M., Bray, S. E., Derek Black, H., Lorimore, S. A., Wright, E. G., Lane, D. P., Meek, D. W., Coates, P. J. & Fuller-Pace, F. V. 18 Jul 2013 In : Oncogene. 32, 29, p. 3461-3469 9 p.

    Research output: Contribution to journalArticle

  14. Early-onset eczema and disease severity are the main risk factors for food sensitization at 3 months of age in exclusively breastfed infants

    Greenblatt, D., Perkin, M., Logan, K., Marrs, T., Radulovic, S., Campbell, L. E., MacCallum, S. F., McLean, W. H. I., Lack, G. & Flohr, C. Jul 2013 In : British Journal of Dermatology. 169, Suppl. 1, p. 113 1 p.PA01

    Research output: Contribution to journalMeeting abstract

  15. High-resolution transcriptional analysis of the regulatory influence of cell-to-cell signalling reveals novel genes that contribute to Xanthomonas phytopathogenesis

    An, S-Q., Febrer, M., McCarthy, Y., Tang, D-J., Clissold, L., Kaithakottil, G., Swarbreck, D., Tang, J-L., Rogers, J., Dow, J. M. & Ryan, R. P. Jun 2013 In : Molecular Microbiology. 88, 6, p. 1058-1069 12 p.

    Research output: Contribution to journalArticle

  16. Generation and characterisation of keratin 7 (K7) knockout mice

    Sandilands, A., Smith, F. J. D., Lunny, D. P., Campbell, L. E., Davidson, K. M., MacCallum, S. F., Corden, L. D., Christie, L., Fleming, S., Lane, E. B. & McLean, W. H. I. 31 May 2013 In : PLoS ONE. 8, 5, 11 p.e64404

    Research output: Contribution to journalArticle

  17. Reliability and validity of genotyping filaggrin null mutations

    Margolis, D. J., Apter, A. J., Mitra, N., Gupta, J., Hoffstad, O., Papadopoulos, M., Rebbeck, T. R., MacCallum, S., Campbell, L. E., Sandilands, A. & McLean, W. H. I. Apr 2013 In : Journal of Dermatological Science. 70, 1, p. 67-68 2 p.

    Research output: Contribution to journalLetter

  18. A Lack of premature termination codon read-through efficacy of PTC124 (Ataluren) in a diverse array of reporter assays

    McElroy, S. P., Nomura, T., Torrie, L. S., Warbrick, E., Gartner, U., Wood, G. & McLean, W. H. I. 2013 In : PLoS Biology. 11, 6, e1001593

    Research output: Contribution to journalArticle

  19. Allele-specific siRNA silencing for the common keratin 12 founder mutation in Meesmann epithelial corneal dystrophy

    Allen, E. H. A., Atkinson, S. D., Liao, H., Moore, J. E., Pedrioli, D. M. L., Smith, F. J. D., McLean, W. H. I. & Moore, C. B. T. 2013 In : Investigative Ophthalmology & Visual Science. 54, 1, p. 494-502 9 p.

    Research output: Contribution to journalArticle

  20. Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting

    Samuelov, L. , Sarig, O. , Harmon, R. M. , Rapaport, D. , Ishida-Yamamoto, A. , Isakov, O. , Koetsier, J. L. , Gat, A. , Goldberg, I. , Bergman, R. , Spiegel, R. , Eytan, O. , Geller, S. , Peleg, S. , Shomron, N. , Goh, C. S. M. , Wilson, N. J. , Smith, F. J. D. , Pohler, E. , Simpson, M. A. & 6 others McLean, W. H. I., Irvine, A. D., Horowitz, M., McGrath, J. A., Green, K. J. & Sprecher, E. 2013 In : Nature Genetics.

    Research output: Contribution to journalLetter

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