MRC Protein Phosphorylation Unit

IFNβ autocrine feedback is required to sustain TLR induced production of MCP-1 in macrophages

Pattison, M. J., MacKenzie, K. F., Elcombe, S. E. & Arthur, J. S. C. 21-May-2013 In : FEBS Letters. 587, 10, p. 1496-1503, 8 p.

Research output: Contribution to journal › Article

Structural biology: Security measures of a master regulator

Alessi, D. R. & Kulathu, Y. 1-May-2013 In : Nature.

Research output: Contribution to journal › Article

The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system

Strickson, S., Campbell, D. G., Emmerich, C. H., Knebel, A., Plater, L., Ritorto, M. S., Shpiro, N. & Cohen, P. 1-May-2013 In : Biochemical Journal. 451, 3, p. 427-437, 11 p.

Research output: Contribution to journal › Article

The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability

Bett, J. S., Ibrahim, A. F. M., Garg, A. K., Kelly, V., Pedrioli, P., Rocha, S. & Hay, R. T. 15-Apr-2013 In : Biochemical Journal. 451, 2, p. 185-194, 10 p., BJ20130026

Research output: Contribution to journal › Article

PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development

Venigalla, R. K. C., McGuire, V. A., Clarke, R., Patterson-Kane, J. C., Najafov, A., Toth, R., McCarthy, P. C., Simeons, F., Stojanovski, L. & Arthur, J. S. C. 3-Apr-2013 In : EMBO Journal. 32, 7, p. 1008-22, 15 p.

Research output: Contribution to journal › Article

The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction

Ohta, A., Schumacher, F-R., Mehellou, Y., Johnson, C., Knebel, A., Macartney, T. J., Wood, N. T., Alessi, D. R. & Kurz, T. 1-Apr-2013 In : Biochemical Journal. 451, 1, p. 111-122, 12 p.

Research output: Contribution to journal › Article

AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to K channels

Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J. Apr-2013 In : Journal of Bioenergetics and Biomembranes. p. 1-13, 13 p.

Research output: Contribution to journal › Article

The clinical significance of calcium-signalling pathways mediating human sperm hyperactivation

Alasmari, W., Barratt, C. L. R., Publicover, S. J., Whalley, K. M., Foster, E., Kay, V., Martins Da Silva, S. & Oxenham, S. K. Apr-2013 In : Human Reproduction. 28, 4, p. 866-876, 11 p.

Research output: Contribution to journal › Article

CSN-and CAND1-dependent remodelling of the budding yeast SCF complex

Zemla, A., Thomas, Y., Kedziora, S., Knebel, A., Wood, N. T., Rabut, G. & Kurz, T. 27-Mar-2013 In : Nature Communications. 4, 1641

Research output: Contribution to journal › Article

Dectin-1 Regulates IL-10 Production via a MSK1/2 and CREB Dependent Pathway and Promotes the Induction of Regulatory Macrophage Markers

Elcombe, S. E., Naqvi, S., Van den Bosch, M. W. M., MacKenzie, K. F., Cianfanelli, F., Brown, G. D. & Arthur, J. S. C. 22-Mar-2013 In : PLoS ONE. 8, 3, 15 p., e60086

Research output: Contribution to journal › Article