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MRC Protein Phosphorylation Unit

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  1. Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains

    Emmerich, C. H., Ordureau, A., Strickson, S., Arthur, J. S. C., Pedrioli, P. G. A., Komander, D. & Cohen, P. 17 Sep 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 38, p. 15247-15252 6 p.

    Research output: Contribution to journalArticle

  2. Localization-dependent and -independent roles of SLX4 in regulating telomeres

    Wilson, J. S. J., Tejera, A. M., Castor, D., Toth, R., Blasco, M. A. & Rouse, J. 12 Sep 2013 In : Cell Reports. 4, 5, p. 853-860 8 p.

    Research output: Contribution to journalArticle

  3. Effect of IRS4 levels on PI 3-kinase signalling.

    Hoxhaj, G., Dissanayake, K. & MacKintosh, C. 10 Sep 2013 In : PLoS ONE. 8, 9, p. e73327 9 p.

    Research output: Contribution to journalArticle

  4. Protein phosphatase 4 is phosphorylated and inactivated by Cdk in response to spindle toxins and interacts with γ-tubulin

    Voss, M., Campbell, K., Saranzewa, N., Campbell, D. G., Hastie, C. J., Peggie, M. W., Martin-Granados, C., Prescott, A. R. & Cohen, P. T. W. 1 Sep 2013 In : Cell Cycle. 12, 17, p. 2876-2887 12 p.

    Research output: Contribution to journalArticle

  5. Hydrophilic strong anion exchange chromatography for proteomics: what's the future outlook?

    Ritorto, M. S., Trost, M. & Cook, K. Sep 2013 In : Bioanalysis. 5, 18, p. 2219-2221 3 p.

    Research output: Contribution to journalArticle

  6. Molecular mechanism of action of metformin: old or new insights?

    Rena, G., Pearson, E. R. & Sakamoto, K. Sep 2013 In : Diabetologia. 56, 9, p. 1898-1906 9 p.

    Research output: Contribution to journalArticle

  7. OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis

    Mevissen, T. E. T., Hospenthal, M. K., Geurink, P. P., Elliott, P. R., Akutsu, M., Arnaudo, N., Ekkebus, R., Kulathu, Y., Wauer, T., El Oualid, F., Freund, S. M. V., Ovaa, H. & Komander, D. 3 Jul 2013 In : Cell. 154, 1, p. 169-184 16 p.

    Research output: Contribution to journalArticle

  8. X-ray crystal structure of ERK5 (MAPK7) in complex with a specific inhibitor

    Elkins, J. M., Wang, J., Deng, X., Pattison, M. J., Arthur, J. S. C., Erazo, T., Gomez, N., Lizcano, J. M., Gray, N. S. & Knapp, S. 13 Jun 2013 In : Journal of Medicinal Chemistry. 56, 11, p. 4413-4421 9 p.

    Research output: Contribution to journalArticle

  9. OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin

    Keusekotten, K., Elliott, P. R., Glockner, L., Fiil, B. K., Damgaard, R. B., Kulathu, Y., Wauer, T., Hospenthal, M. K., Gyrd-Hansen, M., Krappmann, D., Hofmann, K. & Komander, D. 6 Jun 2013 In : Cell. 153, 6, p. 1312-1326 15 p.

    Research output: Contribution to journalArticle

  10. AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels

    Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J. Jun 2013 In : Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.

    Research output: Contribution to journalArticle

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