MRC Protein Phosphorylation Unit

CSN-and CAND1-dependent remodelling of the budding yeast SCF complex

Zemla, A., Thomas, Y., Kedziora, S., Knebel, A., Wood, N. T., Rabut, G. & Kurz, T. 27-Mar-2013 In : Nature Communications. 4, 1641

Research output: Contribution to journal › Article

Dectin-1 Regulates IL-10 Production via a MSK1/2 and CREB Dependent Pathway and Promotes the Induction of Regulatory Macrophage Markers

Elcombe, S. E., Naqvi, S., Van den Bosch, M. W. M., MacKenzie, K. F., Cianfanelli, F., Brown, G. D. & Arthur, J. S. C. 22-Mar-2013 In : PLoS ONE. 8, 3, 15 p., e60086

Research output: Contribution to journal › Article

Regulation of A20 and other OTU deubiquitinases by reversible oxidation

Kulathu, Y., Garcia, F. J., Mevissen, T. E. T., Busch, M., Arnaudo, N., Carroll, K. S., Barford, D. & Komander, D. 5-Mar-2013 In : Nature Communications. 4, 1569

Research output: Contribution to journal › Article

AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues.

Chen, H-Y., Ducommun, S., Quan, C., Xie, B., Li, M., Wasserman, D. H., Sakamoto, K., MacKintosh, C. & Chen, S. 15-Jan-2013 In : Biochemical Journal. 449, 2, p. 479-489, 11 p.

Research output: Contribution to journal › Article

Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity

Yao, C., Johnson, W. M., Gao, Y., Wang, W., Zhang, J., Deak, M., Alessi, D. R., Zhu, X., Mieyal, J. J., Roder, H., Wilson-Delfosse, A. L. & Chen, S. G. 15-Jan-2013 In : Human Molecular Genetics. 22, 2, p. 328-344, 17 p.

Research output: Contribution to journal › Article

PGE2 Induces Macrophage IL-10 Production and a Regulatory-like Phenotype via a Protein Kinase A-SIK-CRTC3 Pathway

Mackenzie, K. F., Clark, K., Naqvi, S., McGuire, V. A., Nöehren, G., Kristariyanto, Y., van den Bosch, M., Mudaliar, M., McCarthy, P. C., Pattison, M. J., Pedrioli, P. G. A., Barton, G. J., Toth, R., Prescott, A. & Arthur, J. S. C. 15-Jan-2013 In : Journal of Immunology. 190, 2, p. 565-77, 13 p.

Research output: Contribution to journal › Article

Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6

MacCallum, S. F., Groves, M. J., James, J., Murray, K., Appleyard, V., Prescott, A. R., Drbal, A. A., Nicolaou, A., Cunningham, J., Haydock, S., Ganley, I. G., Westwood, N. J., Coates, P. J., Lain, S. & Tauro, S. 1-Jan-2013 In : Scientific Reports. 3, 1275

Research output: Contribution to journal › Article

Longitudinal assessment of endothelial function in the microvasculature of mice in-vivo

Belch, J. J. F., Akbar, N., Alapati, V., Petrie, J., Arthur, S. & Khan, F. Jan-2013 In : Microvascular Research. 85, p. 86-92, 7 p.

Research output: Contribution to journal › Article

Ca2+ signalling through CatSper and Ca2+ stores regulate different behaviours in human sperm

Alasmari, W., Costello, S., Correia, J., Oxenham, S. K., Morris, J., Fernandes, L., Ramalho Santos, J., Kirkman-Brown, J., Michelangeli, F., Publicover, S. & Barratt, C. L. R. 2013 In : Journal of Biological Chemistry.

Research output: Contribution to journal › Article

Development of an enzyme-linked immunosorbent assay for detection of cellular and in vivo LRRK2 S935 phosphorylation

Delbroek, L., Van Kolen, K., Steegmans, L., da Cunha, R., Mandemakers, W., Daneels, G., De Bock, P-J., Zhang, J., Gevaert, K., De Strooper, B., Alessi, D. R., Verstreken, P. & Moechars, D. W. 2013 In : Journal of Pharmaceutical and Biomedical Analysis. 76, p. 49-58, 10 p.

Research output: Contribution to journal › Article