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MRC Protein Phosphorylation Unit

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  1. A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

    Alessi, D. R. & 27 others Schönhuber, N., Seidler, B., Schuck, K., Veltkamp, C., Schachtler, C., Zukowska, M., Eser, S., Feyerabend, T. B., Paul, M. C., Eser, P., Klein, S., Lowy, A. M., Banerjee, R., Yang, F., Lee, C-L., Moding, E. J., Kirsch, D. G., Scheideler, A., Varela, I., Bradley, A., Kind, A., Schnieke, A. E., Rodewald, H-R., Rad, R., Schmid, R. M., Schneider, G. & Saur, D. 2014 In : Nature Medicine. 11 p.

    Research output: Contribution to journalArticle

  2. AII amacrine cells discriminate between heterocellular and homocellular locations when assembling connexin36-containing gap junctions

    Meyer, A., Hilgen, G., Dorgau, B., Sammler, E. M., Weiler, R., Monyer, H., Dedek, K. & Hormuzdi, S. G. 2014 In : Journal of Cell Science. 127, 6, p. 1190-1202 13 p.

    Research output: Contribution to journalArticle

  3. ANIA: ANnotation and Integrated Analysis of the 14-3-3 interactome

    Tinti, M., Madeira, F., Murugesan, G., Hoxhaj, G., Toth, R. & Mackintosh, C. 2014 In : Database: the Journal of Biological Databases and Curation. 2014, 15 p.bat085

    Research output: Contribution to journalArticle

  4. GARNL1, a major RalGAP α subunit in skeletal muscle, regulates insulin-stimulated RalA activation and GLUT4 trafficking via interaction with 14-3-3 proteins

    Chen, Q., Quan, C., Xie, B., Chen, L., Zhou, S., Toth, R., Campbell, D. G., Lu, S., Shirakawa, R., Horiuchi, H., Li, C., Yang, Z., MacKintosh, C., Wang, H. Y. & Chen, S. 2014 In : Cellular Signalling. 26, 8, p. 1636-1648 13 p.

    Research output: Contribution to journalArticle

  5. Identification of 2R-ohnologue gene families displaying the same mutation-load skew in multiple cancers

    Tinti, M., Dissanayake, K., Synowsky, S., Albergante, L. & Mackintosh, C. 2014 In : Open Biology. 4, May, 16 p.140029

    Research output: Contribution to journalArticle

  6. Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase

    Banerjee, S., Zagorska, A., Deak, M., Campbell, D. G., Prescott, A. R. & Alessi, D. R. 2014 In : Biochemical Journal. 461, 2, p. 233-245 13 p.

    Research output: Contribution to journalArticle

  7. Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction

    van der Wijst, J., Blanchard, M. G., Woodroof, H. I., Macartney, T. J., Gourlay, R., Hoenderop, J. G., Bindels, R. J. & Alessi, D. R. 2014 In : Biochemical Journal. 460, 2, p. 165-175 11 p.

    Research output: Contribution to journalArticle

  8. Mechanism of Action of Compound-13: an α1-Selective Small Molecule Activator of AMPK

    Hunter, R. W., Foretz, M., Bultot, L., Fullerton, M. D., Deak, M., Ross, F. A., Hawley, S. A., Shpiro, N., Viollet, B., Barron, D., Kemp, B. E., Steinberg, G. R., Hardie, D. G. & Sakamoto, K. 2014 In : Chemistry & Biology. 21, 7, p. 866-879 14 p.

    Research output: Contribution to journalArticle

  9. Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Serine65

    Kazlauskaite, A., Kondapalli, C., Gourlay, R., Campbell, D. G., Ritorto, M. S., Hofmann, K., Alessi, D. R., Knebel, A., Trost, M. & Muqit, M. M. K. 2014 In : Biochemical Journal. 460, 1, p. 127-139 13 p.

    Research output: Contribution to journalArticle

  10. Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling

    Vogt, J., Dingwell, K. S., Herhaus, L., Gourlay, R., Macartney, T., Campbell, D., Smith, J. C. & Sapkota, G. P. 2014 In : Open Biology. 4, FEB

    Research output: Contribution to journalArticle

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