MRC Protein Phosphorylation Unit

ZNRF2 is released from membranes by growth factors and with ZNRF1 regulates the Na+/K+ATPase

Hoxhaj, G., Najafov, A., Toth, R., Campbell, D. G., Prescott, A. R. & MacKintosh, C. 1-Oct-2012 In : Journal of Cell Science. 125, 19, p. 4662-4675

Research output: Contribution to journal › Article

Family with Sequence Similarity 60A (FAM60A) Protein Is a Cell Cycle-fluctuating Regulator of the SIN3-HDAC1 Histone Deacetylase Complex

Munoz, I. M., Macartney, T., Sanchez-Pulido, L., Ponting, C. P., Rocha, S. & Rouse, J. 21-Sep-2012 In : Journal of Biological Chemistry. 287, 39, p. 32346-53, 8 p.

Research output: Contribution to journal › Article

Disruptions on the highways of cellular signalling

Alessi, D. Sep-2012 In : FEBS Journal. 279, p. 23-23, 1 p.

Research output: Contribution to journal › Meeting abstract

Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia

Trost, M., Sauvageau, M., Hérault, O., Deleris, P., Pomiès, C., Chagraoui, J., Mayotte, N., Meloche, S., Sauvageau, G. & Thibault, P. 23-Aug-2012 In : Blood. 120, 8, p. e17-27, 11 p.

Research output: Contribution to journal › Article

Cot/tpl2-MKK1/2-Erk1/2 controls mTORC1-mediated mRNA translation in Toll-like receptor-activated macrophages

Lopez Pelaez, M., Sanz, C., Herrero, C., Fernandez, M., Alemany, S., Fumagalli, S. & Guerra, S. 1-Aug-2012 In : Molecular Biology of the Cell. 23, 15, p. 2982-2992, 11 p.

Research output: Contribution to journal › Article

Brain penetrant LRRK2 inhibitor

Choi, H. G., Zhang, J., Deng, X., Hatcher, J. M., Patricelli, M. P., Zhao, Z., Alessi, D. R. & Gray, N. S. Aug-2012 In : ACS Medicinal Chemistry Letters. 3, 8, p. 658-662, 5 p.

Research output: Contribution to journal › Article

Effect of heterozygous deletion of WNK1 on the WNK-OSR1/SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels

Susa, K., Kita, S., Iwamoto, T., Yang, S-S., Lin, S-H., Ohta, A., Sohara, E., Rai, T., Sasaki, S., Alessi, D. R. & Uchida, S. Aug-2012 In : Clinical and Experimental Nephrology. 16, 4, p. 530-538, 9 p.

Research output: Contribution to journal › Article

P38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

Risco, A., Del Dresno, C., Mambol, A., Alsina-Beauchamp, D., MacKenzie, K. F., Yang, H-T., Barber, D. F., Morcelle, C., Arthur, J. S. C., Ley, S. C., Ardavin, C. F. & Cuenda, A. 10-Jul-2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 28, p. 11200-11205, 6 p.

Research output: Contribution to journal › Article

Phosphatases in SMAD regulation

Bruce, D. L. & Sapkota, G. P. 4-Jul-2012 In : FEBS Letters. 586, 14, p. 1897-1905, 9 p.

Research output: Contribution to journal › Article

Quantitative proteomics reveals that only a subset of the endoplasmic reticulum contributes to the phagosome

Campbell-Valois, F-X., Trost, M., Chemali, M., Laplante, A., Duclos, S., Sadeghi, S., Rondeau, C., Desjardins, M., Bell, C., Gagnon, E., Thibault, P., Dill, B. D., Morrow, I. C. & Hatsuzawa, K. 1-Jul-2012 In : Molecular & Cellular Proteomics. 11, 7

Research output: Contribution to journal › Article