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MRC Protein Phosphorylation Unit

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  1. Structural insights into the recognition of substrates and activators by the OSR1 kinase

    Villa, F., Goebel, J., Rafiqi, F. H., Deak, M., Thastrup, J., Alessi, D. R. & van Aalten, D. M. F. 1 Sep 2007 In : EMBO Reports. 8, 9, p. 839-845 7 p.

    Research output: Contribution to journalArticle

  2. Characterization of a protein kinase B inhibitor in vitro and in insulin-treated liver cells

    Logie, L., Ruiz-Alcaraz, A. J., Keane, M., Woods, Y. L., Bain, J., Marquez, R., Alessi, D. R. & Sutherland, C. Sep 2007 In : Diabetes. 56, 9, p. 2218-2227 10 p.

    Research output: Contribution to journalArticle

  3. PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex

    Fonseca, B. D., Smith, E. M., Lee, V. H. -Y., MacKintosh, C. & Proud, C. G. 24 Aug 2007 In : Journal of Biological Chemistry. 282, 34, p. 24514-24524 11 p.

    Research output: Contribution to journalArticle

  4. Identification of protor as a novel rictor-binding component of mTOR complex-2

    Pearce, L. R., Huang, X., Boudeau, J., Pawłowski, R., Wullschleger, S., Deak, M., Ibrahim, A. F. M., Gourlay, R., Magnuson, M. A. & Alessi, D. R. 1 Aug 2007 In : Biochemical Journal. 405, 3, p. 513-522 10 p.

    Research output: Contribution to journalArticle

  5. p38 MAP-kinases pathway regulation, function and role in human diseases

    Cuenda, A. & Rousseau, S. Aug 2007 In : Biochimica et Biophysica Acta: General Subjects. 1773, 8, p. 1358-75 18 p.

    Research output: Contribution to journalArticle

  6. Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage

    Munoz, I. M., Jowsey, P. A., Toth, R. & Rouse, J. Aug 2007 In : Nucleic Acids Research. 35, 16, p. 5312-5322 11 p.

    Research output: Contribution to journalArticle

  7. Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS

    McCoy, C. E., Macdonald, A., Morrice, N. A., Campbell, D. G., Deak, M., Toth, R., McIlrath, J. & Arthur, J. S. C. 15 Mar 2007 In : Biochemical Journal. 402, 3, p. 491-501 11 p.

    Research output: Contribution to journalArticle

  8. Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide

    Windheim, M., Lang, C., Peggie, M., Plater, L. A. & Cohen, P. 9 Mar 2007 In : Biochemical Journal. 404, 2, p. 179-90 12 p.

    Research output: Contribution to journalArticle

  9. SARP, a new alternatively spliced protein phosphatase 1 and DNA interacting protein

    Browne, G. J., Fardilha, M., Oxenham, S. K., Wu, W., Helps, N. R., da Cruz E. Silva, O. A. B., Cohen, P. T. W. & da Cruz E. Silva, E. F. 15 Feb 2007 In : Biochemical Journal. 402, 1, p. 187-196 10 p.

    Research output: Contribution to journalArticle

  10. Balancing BMP signaling through integrated inputs into the Smad1 linker

    Sapkota, G., Alarcón, C., Spagnoli, F. M., Brivanlou, A. H. & Massagué, J. 9 Feb 2007 In : Molecular Cell. 25, 3, p. 441-454 14 p.

    Research output: Contribution to journalArticle

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