MRC Protein Phosphorylation Unit

O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release

Pathak, S., Borodkin, V. S., Albarbarawi, O., Campbell, D. G., Ibrahim, A. & van Aalten, D. M. F. 21-Mar-2012 In : EMBO Journal. 31, 6, p. 1394-1404, 11 p.

Research output: Contribution to journal › Article

A new role of AMP-activated protein kinase in regulating proliferation of mesenchymal stem cells

Bertrand, L., Balteau, M., Timmermans, A., Viollet, B., Sakamoto, K., Feron, O., Horman, S., Vanoverschelde, J. L., Beauloye, C. & De Meester, C. 15-Mar-2012 In : Cardiovascular Research. 93, p. S96-S97, 2 p., P-498

Research output: Contribution to journal › Article

Potentiation effect of the AMPK activator A-769662 on cardiac myocytes metabolism and survival

Timmermans, A., Ginion, A., De Meester, C., Sakamoto, K., Vanoverschelde, J-L., Horman, S., Beauloye, C. & Bertrand, L. 15-Mar-2012 In : Cardiovascular Research. 93, p. S72-S73, 2 p., P-362

Research output: Contribution to journal › Article

Phenformin as prophylaxis and therapy in breast cancer xenografts

Appleyard, M. V. C. L., Murray, K. E., Coates, P. J., Wullschleger, S., Bray, S. E., Kernohan, N. M., Fleming, S., Alessi, D. R. & Thompson, A. M. 13-Mar-2012 In : British Journal of Cancer. 106, 6, p. 1117-1122, 6 p.

Research output: Contribution to journal › Article

Characterization of TAE684 as a potent LRRK2 kinase inhibitor

Zhang, J., Deng, X., Choi, H. G., Alessi, D. R. & Gray, N. S. 1-Mar-2012 In : Bioorganic & Medicinal Chemistry Letters. 22, 5, p. 1864-1869, 6 p.

Research output: Contribution to journal › Article

Discovery of potent and selective covalent inhibitors of JNK

Zhang, T., Inesta-Vaquera, F., Niepel, M., Zhang, J., Ficarro, S. B., Machleidt, T., Xie, T., Marto, J. A., Kim, N., Sim, T., Laughlin, J. D., Park, H., LoGrasso, P. V., Patricelli, M., Nomanbhoy, T. K., Sorger, P. K., Alessi, D. R. & Gray, N. S. 27-Jan-2012 In : Chemistry & Biology. 19, 1, p. 140-154, 15 p.

Research output: Contribution to journal › Article

The Vibrio cholerae colonization factor GbpA possesses a modular structure that governs binding to different host surfaces

Wong, E., Vaaje-Kolstad, G., Ghosh, A., Hurtado-Guerrero, R., Konarev, P. V., Ibrahim, A. F. M., Svergun, D. I., Eijsink, V. G. H., Chatterjee, N. S. & van Aalten, D. M. F. 12-Jan-2012 In : PLoS Pathogens. 8, 1, e1002373

Research output: Contribution to journal › Article

Phosphorylation of FOXO3a on Ser-7 by p38 promotes its nuclear localization in response to doxorubicin

Ho, K-K., McGuire, V. A., Koo, C-Y., Muir, K. W., de Olano, N., Maifoshie, E., Kelly, D. J., McGovern, U. B., Monteiro, L. J., Gomes, A. R., Nebreda, A. R., Campbell, D. G., Arthur, J. S. C. & Lam, E. W. -F. 6-Jan-2012 In : Journal of Biological Chemistry. 287, 2, p. 1545-1555, 11 p.

Research output: Contribution to journal › Article

Characterization of the cellular action of the MSK inhibitor SB-747651A

Naqvi, S., Macdonald, A., McCoy, C. E., Darragh, J., Reith, A. D. & Arthur, J. S. C. 1-Jan-2012 In : Biochemical Journal. 441, p. 347-357, 11 p.

Research output: Contribution to journal › Article

Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system

Goh, E. T. H., Arthur, J. S. C., Cheung, P. C. F., Akira, S., Toth, R. & Cohen, P. 1-Jan-2012 In : Biochemical Journal. 441, p. 339-346, 8 p.

Research output: Contribution to journal › Article