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MRC Protein Phosphorylation Unit

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  1. PGE2 induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway

    Mackenzie, K. F., Clark, K., Naqvi, S., McGuire, V. A., Nöehren, G., Kristariyanto, Y., van den Bosch, M., Mudaliar, M., McCarthy, P. C., Pattison, M. J., Pedrioli, P. G. A., Barton, G. J., Toth, R., Prescott, A. & Arthur, J. S. C. 15 Jan 2013 In : Journal of Immunology. 190, 2, p. 565-577 13 p.

    Research output: Contribution to journalArticle

  2. Longitudinal assessment of endothelial function in the microvasculature of mice in-vivo

    Belch, J. J. F., Akbar, N., Alapati, V., Petrie, J., Arthur, S. & Khan, F. Jan 2013 In : Microvascular Research. 85, p. 86-92 7 p.

    Research output: Contribution to journalArticle

  3. Coibamide A Induces mTOR-Independent Autophagy and Cell Death in Human Glioblastoma Cells

    Hau, A. M., Greenwood, J. A., Loehr, C. V., Serrill, J. D., Proteau, P. J., Ganley, I. G., McPhail, K. L. & Ishmael, J. E. 2013 In : PLoS ONE. 8, 6, 16 p. e65250

    Research output: Contribution to journalArticle

  4. Cross talk between the Akt and p38α pathways in macrophages downstream of toll-like receptor signaling

    McGuire, V. A., Gray, A., Monk, C. E., Santos, S. G., Lee, K., Aubareda, A., Crowe, J., Ronkina, N., Schwermann, J., Batty, I. H., Leslie, N. R., Dean, J. L. E., O'Keefe, S. J., Boothby, M., Gaestel, M. & Arthur, J. S. C. 2013 In : Molecular and Cellular Biology. 33, 21, p. 4152-4165 14 p.

    Research output: Contribution to journalArticle

  5. Development of an enzyme-linked immunosorbent assay for detection of cellular and in vivo LRRK2 S935 phosphorylation

    Delbroek, L., Van Kolen, K., Steegmans, L., da Cunha, R., Mandemakers, W., Daneels, G., De Bock, P-J., Zhang, J., Gevaert, K., De Strooper, B., Alessi, D. R., Verstreken, P. & Moechars, D. W. 2013 In : Journal of Pharmaceutical and Biomedical Analysis. 76, p. 49-58 10 p.

    Research output: Contribution to journalArticle

  6. Dual regulation of Glycogen Synthase Kinase 3 (GSK3)alpha/beta by Protein Kinase C (PKC)alpha and Akt promotes Thrombin-mediated Integrin alpha(IIb)beta(3) activation and granule secretion in platelets

    Moore, S. F., van den Bosch, M. T. J., Hunter, R. W., Sakamoto, K., Poole, A. W. & Hers, I. 2013 In : Journal of Biological Chemistry. 288, 6, p. 3918-3928 11 p.

    Research output: Contribution to journalArticle

  7. Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6

    MacCallum, S. F., Groves, M. J., James, J., Murray, K., Appleyard, V., Prescott, A. R., Drbal, A. A., Nicolaou, A., Cunningham, J., Haydock, S., Ganley, I. G., Westwood, N. J., Coates, P. J., Lain, S. & Tauro, S. 2013 In : Scientific Reports. 3, 1275

    Research output: Contribution to journalArticle

  8. Hydrophilic Strong Anion Exchange (hSAX) Chromatography for Highly Orthogonal Peptide Separation of Complex Proteomes

    Ritorto, S., Cook, K., Tyagi, K., Pedrioli, P. G. A. & Trost, M. 2013 In : Journal of Proteome Research. 12, 6, p. 2449-2457 9 p.

    Research output: Contribution to journalArticle

  9. Kinase drug discovery: What's next in the field?

    Cohen, P. & Alessi, D. R. 2013 In : ACS Chemical Biology. 8, 1, p. 96-104 9 p.

    Research output: Contribution to journalArticle

  10. Loss of iron triggers PINK1/Parkin-independent mitophagy

    Allen, G. F. G., Toth, R., James, J. & Ganley, I. G. 2013 In : EMBO Reports. 14, p. 1127-1135 9 p.

    Research output: Contribution to journalArticle

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