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MRC Protein Phosphorylation Unit

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  1. MSK1 and MSK2 inhibit lipopolysaccharide-induced prostaglandin production via an interleukin-10 feedback loop

    MacKenzie, K. F., Van den Bosch, M. W. M., Naqvi, S., Elcombe, S. E., McGuire, V. A., Reith, A. D., Blackshear, P. J., Dean, J. L. E. & Arthur, J. S. C. Apr 2013 In : Molecular and Cellular Biology. 33, 7, p. 1456-1467 12 p.

    Research output: Contribution to journalArticle

  2. The clinical significance of calcium-signalling pathways mediating human sperm hyperactivation

    Alasmari, W., Barratt, C. L. R., Publicover, S. J., Whalley, K. M., Foster, E., Kay, V., Martins Da Silva, S. & Oxenham, S. K. Apr 2013 In : Human Reproduction. 28, 4, p. 866-876 11 p.

    Research output: Contribution to journalArticle

  3. CSN-and CAND1-dependent remodelling of the budding yeast SCF complex

    Zemla, A., Thomas, Y., Kedziora, S., Knebel, A., Wood, N. T., Rabut, G. & Kurz, T. 27 Mar 2013 In : Nature Communications. 4, 1641

    Research output: Contribution to journalArticle

  4. Dectin-1 Regulates IL-10 Production via a MSK1/2 and CREB Dependent Pathway and Promotes the Induction of Regulatory Macrophage Markers

    Elcombe, S. E., Naqvi, S., Van den Bosch, M. W. M., MacKenzie, K. F., Cianfanelli, F., Brown, G. D. & Arthur, J. S. C. 22 Mar 2013 In : PLoS ONE. 8, 3, 15 p.e60086

    Research output: Contribution to journalArticle

  5. Regulation of A20 and other OTU deubiquitinases by reversible oxidation

    Kulathu, Y., Garcia, F. J., Mevissen, T. E. T., Busch, M., Arnaudo, N., Carroll, K. S., Barford, D. & Komander, D. 5 Mar 2013 In : Nature Communications. 4, 1569

    Research output: Contribution to journalArticle

  6. Ca2+ signalling through CatSper and Ca2+ stores regulate different behaviours in human sperm

    Alasmari, W., Costello, S., Correia, J., Oxenham, S. K., Morris, J., Fernandes, L., Ramalho Santos, J., Kirkman-Brown, J., Michelangeli, F., Publicover, S. & Barratt, C. L. R. 1 Mar 2013 In : Journal of Biological Chemistry. 288, 9, p. 6248-6258 11 p.

    Research output: Contribution to journalArticle

  7. Structural insights into the activation of MST3 by MO25

    Mehellou, Y., Alessi, D. R., Macartney, T. J., Szklarz, M., Knapp, S. & Elkins, J. M. 15 Feb 2013 In : Biochemical and Biophysical Research Communications. 431, 3, p. 604-609 6 p.

    Research output: Contribution to journalArticle

  8. Anorexigenic and orexigenic hormone modulation of mammalian target of rapamycin complex 1 activity and the regulation of hypothalamic agouti-related protein mRNA expression

    Watterson, K. R., Bestow, D., Gallagher, J., Hamilton, D. L., Ashford, F. B., Meakin, P. J. & Ashford, M. L. J. Feb 2013 In : NeuroSignals. 21, 1-2, p. 28-41 14 p.

    Research output: Contribution to journalArticle

  9. AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues.

    Chen, H-Y., Ducommun, S., Quan, C., Xie, B., Li, M., Wasserman, D. H., Sakamoto, K., MacKintosh, C. & Chen, S. 15 Jan 2013 In : Biochemical Journal. 449, 2, p. 479-489 11 p.

    Research output: Contribution to journalArticle

  10. Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity

    Yao, C., Johnson, W. M., Gao, Y., Wang, W., Zhang, J., Deak, M., Alessi, D. R., Zhu, X., Mieyal, J. J., Roder, H., Wilson-Delfosse, A. L. & Chen, S. G. 15 Jan 2013 In : Human Molecular Genetics. 22, 2, p. 328-344 17 p.

    Research output: Contribution to journalArticle

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