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MRC Protein Phosphorylation Unit

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  1. The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

    Hawley, S. A., Fullerton, M. D., Ross, F. A., Schertzer, J. D., Chevtzoff, C., Walker, K. J., Peggie, M. W., Zibrova, D., Green, K. A., Mustard, K. J., Kemp, B. E., Sakamoto, K., Steinberg, G. R. & Hardie, D. G. 18 May 2012 In : Science. 336, 6083, p. 918-922 5 p.

    Research output: Contribution to journalArticle

  2. Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B cell activation and autoantibody production

    Jayachandran, N., Landego, I., Gibson, I., Miller, A., Wullschleger, S., Alessi, D. & Marshall, A. 1 May 2012 In : Journal of Immunology. 188, Suppl.1, 159.5

    Research output: Contribution to journalMeeting abstract

  3. Thr(649)Ala-AS160 knock-in mutation does not impair contraction/AICAR-induced glucose transport in mouse muscle

    Ducommun, S., Wang, H. Y., Sakamoto, K., MacKintosh, C. & Chen, S. May 2012 In : American Journal of Physiology, Endocrinology and Metabolism. 302, 9, p. E1036-E1043 8 p.

    Research output: Contribution to journalArticle

  4. Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death

    Gammoh, N., Lam, D., Puente, C., Marks, P. A., Jiang, X. & Ganley, I. 24 Apr 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 17, p. 6561-6565 5 p.

    Research output: Contribution to journalArticle

  5. AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

    Bultot, L., Guigas, B., Von Wilamowitz-Moellendorff, A., Maisin, L., Vertommen, D., Hussain, N., Beullens, M., Guinovart, J. J., Foretz, M., Viollet, B., Sakamoto, K., Hue, L. & Rider, M. H. 1 Apr 2012 In : Biochemical Journal. 443, p. 193-203 11 p.

    Research output: Contribution to journalArticle

  6. The anti-neurodegenerative agent clioquinol regulates the transcription factor FOXO1a

    Cameron, A. R., Wallace, K., Logie, L., Prescott, A. R., Unterman, T. G., Harthill, J. & Rena, G. 1 Apr 2012 In : Biochemical Journal. 443, 1, p. 57-64 8 p.

    Research output: Contribution to journalArticle

  7. O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release

    Pathak, S., Borodkin, V. S., Albarbarawi, O., Campbell, D. G., Ibrahim, A. & van Aalten, D. M. F. 21 Mar 2012 In : EMBO Journal. 31, 6, p. 1394-1404 11 p.

    Research output: Contribution to journalArticle

  8. Phenformin as prophylaxis and therapy in breast cancer xenografts

    Appleyard, M. V. C. L., Murray, K. E., Coates, P. J., Wullschleger, S., Bray, S. E., Kernohan, N. M., Fleming, S., Alessi, D. R. & Thompson, A. M. 13 Mar 2012 In : British Journal of Cancer. 106, 6, p. 1117-1122 6 p.

    Research output: Contribution to journalArticle

  9. Characterization of TAE684 as a potent LRRK2 kinase inhibitor

    Zhang, J., Deng, X., Choi, H. G., Alessi, D. R. & Gray, N. S. 1 Mar 2012 In : Bioorganic & Medicinal Chemistry Letters. 22, 5, p. 1864-1869 6 p.

    Research output: Contribution to journalArticle

  10. Potentiation effect of the AMPK activator A-769662 on cardiac myocytes metabolism and survival

    Timmermans, A., Ginion, A., De Meester, C., Sakamoto, K., Vanoverschelde, J-L., Horman, S., Beauloye, C. & Bertrand, L. Mar 2012 In : Cardiovascular Research. 93, S1, p. S72-S73 2 p.P-362

    Research output: Contribution to journalArticle

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