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MRC Protein Phosphorylation Unit

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  1. The anti-inflammatory compound BAY-11-7082 is a potent inhibitor of protein tyrosine phosphatases

    Krishnan, N., Bencze, G., Cohen, P. & Tonks, N. K. 2013 In : FEBS Journal. 280, 12, p. 2830-2841 12 p.

    Research output: Contribution to journalArticle

  2. The impact of KLF2 modulation on the transcriptional program and function of CD8 T Cells

    Preston, G. C., Feijoo-Carnero, C., Schurch, N., Cowling, V. H. & Cantrell, D. A. 2013 In : PLoS ONE. 8, 10, 16 p.e77537

    Research output: Contribution to journalArticle

  3. The ULK1 complex Sensing nutrient signals for autophagy activation

    Wong, P-M., Puente, C., Ganley, I. G. & Jiang, X. 2013 In : Autophagy. 9, 2, p. 124-137 14 p.

    Research output: Contribution to journalArticle

  4. Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P-3-dependent mechanisms leading to resistance to PDK1 inhibitors

    Najafov, A., Shpiro, N. & Alessi, D. R. Dec 2012 In : Biochemical Journal. 448, 2, p. 285-295 11 p.

    Research output: Contribution to journalArticle

  5. Selective kinase inhibitors as tools for neuroscience research

    Martin, K. J. & Arthur, J. S. C. Dec 2012 In : Neuropharmacology. 63, 7, p. 1227-1237 11 p.

    Research output: Contribution to journalArticle

  6. Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases

    McIver, E. G., Bryans, J., Birchall, K., Chugh, J., Drake, T., Lewis, S. J., Osborne, J., Smiljanic-Hurley, E., Tsang, W., Kamal, A., Levy, A., Newman, M., Taylor, D., Arthur, J. S. C., Clark, K. & Cohen, P. Dec 2012 In : Bioorganic & Medicinal Chemistry Letters. 22, 23, p. 7169-7173 5 p.

    Research output: Contribution to journalArticle

  7. Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase

    Shehata, S. N., Hunter, R. W., Ohta, E., Peggie, M. W., Lou, H. J., Sicheri, F., Zegiraj, E., Turk, B. E. & Sakamoto, K. Nov 2012 In : Cellular Signalling. 24, 11, p. 2085-2094 10 p.

    Research output: Contribution to journalArticle

  8. Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-beta pathway

    Bruce, D. L., Macartney, T., Yong, W., Shou, W. & Sapkota, G. P. Nov 2012 In : Cellular Signalling. 24, 11, p. 1999-2006 8 p.

    Research output: Contribution to journalArticle

  9. ZNRF2 is released from membranes by growth factors and with ZNRF1 regulates the Na+/K+ATPase

    Hoxhaj, G., Najafov, A., Toth, R., Campbell, D. G., Prescott, A. R. & MacKintosh, C. 1 Oct 2012 In : Journal of Cell Science. 125, 19, p. 4662-4675 14 p.

    Research output: Contribution to journalArticle

  10. Family with Sequence Similarity 60A (FAM60A) Protein Is a Cell Cycle-fluctuating Regulator of the SIN3-HDAC1 Histone Deacetylase Complex

    Munoz, I. M., Macartney, T., Sanchez-Pulido, L., Ponting, C. P., Rocha, S. & Rouse, J. 21 Sep 2012 In : Journal of Biological Chemistry. 287, 39, p. 32346-53 8 p.

    Research output: Contribution to journalArticle

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