Oncology & Molecular Medicine

Oesophageal bacterial biofilm changes in gastro-oesophageal reflux disease, Barrett's and oesophageal carcinoma: association or causality?

Blackett, K. L., Siddhi, S. S., Cleary, S., Steed, H., Miller, M. H., Macfarlane, S., Macfarlane, G. T. & Dillon, J. F. Jun-2013 In : Alimentary Pharmacology & Therapeutics. 37, 11, p. 1084-1092, 9 p.

Research output: Contribution to journal › Article

Effects of antibiotics on bacterial species composition and metabolic activities in chemostats containing defined populations of human gut microorganisms

Newton, D. F., Macfarlane, S. & Macfarlane, G. T. May-2013 In : Antimicrobial Agents and Chemotherapy. 57, 5, p. 2016-2025, 10 p.

Research output: Contribution to journal › Article

Host microRNA molecular signatures associated with human H1N1 and H3N2 influenza A viruses reveal an unanticipated antiviral activity for miR-146a

Terrier, O., Textoris, J., Carron, C., Marcel, V., Bourdon, J-C. & Rosa-Calatrava, M. May-2013 In : Journal of General Virology. 94, 5, p. 985-95, 11 p.

Research output: Contribution to journal › Article

Neurovascular screening in hereditary haemorrhagic telangiectasia: dilemmas for the paediatric neuroscience community

Ganesan, V., Robertson, F. & Berg, J. May-2013 In : Developmental Medicine and Child Neurology. 55, 5, p. 405-407, 3 p.

Research output: Contribution to journal › Article

p53 Protein Isoforms: Key Regulators in the Front Line of Pathogen Infections?

Terrier, O., Bourdon, J-C. & Rosa-Calatrava, M. 4-Apr-2013 In : PLoS Pathogens. 9, 4, p. e1003246

Research output: Contribution to journal › Article

Azacitidine-eligibility in higher-risk myelodysplastic syndromes and chronic myelomonocytic leukaemia: A registry-based study

Durairaj, S., Keenan, N., Hyslop, A., Groves, M. J., Bowen, D. T. & Tauro, S. Apr-2013 In : British Journal of Haematology. 161, 2, p. 280-282, 3 p.

Research output: Contribution to journal › Letter

Palliative care for patients with gastrointestinal cancer dying under surgical care: a case for acute palliative care units?

Young, J. A., Waugh, L., McPhillips, G., Levack, P. & Thompson, A. M. Apr-2013 In : Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 11, 2, p. 72-75, 4 p.

Research output: Contribution to journal › Article

Reliability and validity of genotyping filaggrin null mutations

Margolis, D. J., Apter, A. J., Mitra, N., Gupta, J., Hoffstad, O., Papadopoulos, M., Rebbeck, T. R., MacCallum, S., Campbell, L. E., Sandilands, A. & McLean, W. H. I. Apr-2013 In : Journal of Dermatological Science. 70, 1, p. 67-68, 2 p.

Research output: Contribution to journal › Letter

The clinical significance of calcium-signalling pathways mediating human sperm hyperactivation

Alasmari, W., Barratt, C. L. R., Publicover, S. J., Whalley, K. M., Foster, E., Kay, V., Martins Da Silva, S. & Oxenham, S. K. Apr-2013 In : Human Reproduction. 28, 4, p. 866-876, 11 p.

Research output: Contribution to journal › Article

Trimethoprim prescription and subsequent resistance in childhood urinary infection: multilevel modelling analysis

Duffy, M. A., Hernandez-Santiago, V., Orange, G., Davey, P. G. & Guthrie, B. Apr-2013 In : British Journal of General Practice. 63, 609, p. 238-43, 6 p.

Research output: Contribution to journal › Article

What should it take to describe a substance or product as 'sperm-safe'

Mortimer, D., Barratt, C. L. R., Björndahl, L., de Jager, C., Jequier, A. M. & Muller, C. H. Apr-2013 In : Human Reproduction Update. 19, SUPPL1, p. i1-i45, 45 p.

Research output: Contribution to journal › Article

Measuring endogenous insulin secretion in type 1 diabetes is life changing

Connelly, P. J., Gellatly, E., Bell, L., Shepherd, M., Hattersley, A. T. & Pearson, E. Mar-2013 In : Diabetic Medicine. 30, Suppl. 1, p. 94-95, 2 p., P215

Research output: Contribution to journal › Meeting abstract

Nine out of 10 sunbeds in England emit ultraviolet radiation levels that exceed current safety limits

Tierney, P., Ferguson, J., Ibbotson, S., Dawe, R., Eadie, E. & Moseley, H. Mar-2013 In : British Journal of Dermatology. 168, 3, p. 602-608, 7 p.

Research output: Contribution to journal › Article

Phase IIa randomized, placebo-controlled study of antimicrobial photodynamic therapy in bacterially colonized, chronic leg ulcers and diabetic foot ulcers: a new approach to antimicrobial therapy

Morley, S., Griffiths, J., Philips, G., Moseley, H., O'Grady, C., Mellish, K., Lankester, C. L., Faris, B., Young, R. J., Brown, S. B. & Rhodes, L. E. Mar-2013 In : British Journal of Dermatology. 168, 3, p. 617-624, 8 p.

Research output: Contribution to journal › Article

Transrectal quantitative shear wave elastography in the detection and characterisation of prostate cancer

Ahmad, S., Cao, R., Varghese, T., Bidaut, L. & Nabi, G. Mar-2013 In : Surgical Endoscopy. p. 1-8, 8 p.

Research output: Contribution to journal › Article

Use of aspirin post-diagnosis in a cohort of patients with colorectal cancer and its association with all-cause and colorectal cancer specific mortality

McCowan, C., Munro, A. J., Donnan, P. T. & Steele, R. J. C. Mar-2013 In : European Journal of Cancer. 49, 5, p. 1049-1057, 9 p.

Research output: Contribution to journal › Article

Utility of prognostic genomic tests in breast cancer practice: The IMPAKT 2012 Working Group Consensus Statement

Azim, H. A., Michiels, S., Zagouri, F., Delaloge, S., Filipits, M., Namer, M., Neven, P., Symmans, W. F., Thompson, A., Andre, F., Loi, S. & Swanton, C. Mar-2013 In : Annals of Oncology. 24, 3, p. 647-654, 8 p.

Research output: Contribution to journal › Article

Improved short term surgical outcomes in Scotland for oesophageal cancer

Young, J. A., Shimi, S. M., Waugh, L., McPhillips, G. & Thompson, A. M. Feb-2013 In : European Journal of Surgical Oncology. 39, 2, p. 131-135, 5 p.

Research output: Contribution to journal › Article

Interactions of Apoptotic Cells with Macrophages in Radiation-Induced Bystander Signaling

Rastogi, S., Boylan, M., Wright, E. G. & Coates, P. J. Feb-2013 In : Radiation Research. 179, 2, p. 135-145, 11 p.

Research output: Contribution to journal › Article

Oral 5-aminolevulinic acid induced photodynamic diagnostic ureterorenoscopy - does the blood pressure require monitoring?

Bondad, J., Aboumarzouk, O. M., Moseley, H. & Kata, S. G. Feb-2013 In : Photodiagnosis and Photodynamic Therapy. 10, 1, p. 39-41, 3 p.

Research output: Contribution to journal › Article

p68/DdX5 supports β-Catenin & RNAP II during androgen receptor mediated transcription in prostate cancer

Clark, E. L., Hadjimichael, C., Temperley, R., Barnard, A., Fuller-Pace, F. V. & Robson, C. N. 17-Jan-2013 In : PLoS ONE. 8, 1, 10 p., e54150

Research output: Contribution to journal › Article

p53 is activated in response to disruption of the pre-mRNA splicing machinery

Allende-Vega, N., Dayal, S., Agarwala, U., Sparks, A., Bourdon, J-C. & Saville, M. K. 3-Jan-2013 In : Oncogene. 32, 1, p. 1-14, 14 p.

Research output: Contribution to journal › Article

Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6

MacCallum, S. F., Groves, M. J., James, J., Murray, K., Appleyard, V., Prescott, A. R., Drbal, A. A., Nicolaou, A., Cunningham, J., Haydock, S., Ganley, I. G., Westwood, N. J., Coates, P. J., Lain, S. & Tauro, S. 1-Jan-2013 In : Scientific Reports. 3, 1275

Research output: Contribution to journal › Article

Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation

Dichtel-Danjoy, M-L., Ma, D., Dourlen, P., Chatelain, G., Napoletano, F., Robin, M., Corbet, M., Levet, C., Hafsi, H., Hainaut, P., Ryoo, H. D., Bourdon, J-C. & Mollereau, B. Jan-2013 In : Cell Death & Differentiation. 20, 1, p. 108-116, 9 p.

Research output: Contribution to journal › Article

A surveillance model for skin cancer in organ transplant recipients: A 22-year prospective study in an ethnically diverse population

Harwood, C. A., Mesher, D., McGregor, J. M., Mitchell, L., Leedham-Green, M., Raftery, M., Cerio, R., Leigh, I. M., Sasieni, P. & Proby, C. M. Jan-2013 In : American Journal of Transplantation. 13, 1, p. 119-129, 11 p.

Research output: Contribution to journal › Article

A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

Wypijewski, K. J., Howie, J., Reilly, L., Tulloch, L. B., Aughton, K. L., McLatchie, L. M., Shattock, M. J., Calaghan, S. C. & Fuller, W. 2013 In : Journal of Biological Chemistry.

Research output: Contribution to journal › Article

Ca2+ signalling through CatSper and Ca2+ stores regulate different behaviours in human sperm

Alasmari, W., Costello, S., Correia, J., Oxenham, S. K., Morris, J., Fernandes, L., Ramalho Santos, J., Kirkman-Brown, J., Michelangeli, F., Publicover, S. & Barratt, C. L. R. 2013 In : Journal of Biological Chemistry.

Research output: Contribution to journal › Article

Current controversies in breast cancer surgery

Critchley, A. C., Thompson, A. M., Chan, H. Y. & Reed, M. W. 2013 In : Clinical Oncology. 25, 2, p. 101-108, 8 p.

Research output: Contribution to journal › Article

DEAD box RNA helicase functions in cancer

Fuller-Pace, F. V. 2013 In : RNA Biology. 10, 1, p. 121-132, 12 p.

Research output: Contribution to journal › Article

Expression of TP53 isoforms p53β or p53γ enhances chemosensitivity in TP53(null) cell lines

Silden, E., Hjelle, S. M., Wergeland, L., Sulen, A., Andresen, V., Bourdon, J-C., Micklem, D. R., McCormack, E. & Gjertsen, B. T. 2013 In : PLoS ONE. 8, 2, 11 p., e56276

Research output: Contribution to journal › Article

Longitudinal Analyses of Gut Mucosal Microbiotas in Ulcerative Colitis in Relation to Patient Age and Disease Severity and Duration

Fite, A., Macfarlane, S., Furrie, E., Bahrami, B., Cummings, J. H., Steinke, D. T. & Macfarlane, G. T. 2013 In : Journal of Clinical Microbiology. 51, 3, p. 849-856, 8 p.

Research output: Contribution to journal › Article

Multiparameter DNA content analysis identifies distinct groups in primary breast cancer

Dayal, J., Sales, M. J., Corver, W. E., Purdie, C. A., Jordan, L. B., Quinlan, P. R., Baker, L., ter Haar, N. T., Pratt, N. R. & Thompson, A. M. 2013 In : British Journal of Cancer. 108, 4, p. 873-880, 8 p.

Research output: Contribution to journal › Article

Photopatch testing: recommendations for a European photopatch test baseline series

Gonçalo, M., Ferguson, J., Bonevalle, A., Bruynzeel, D. P., Giménez-Arnau, A., Goossens, A., Kerr, A., Lecha, M., Neumann, N., Niklasson, B., Pigatto, P., Rhodes, L. E., Rustemeyer, T., Sarkany, R., Thomas, P. & Wilkinson, M. 2013 In : Contact Dermatitis. 68, 4, p. 239-243, 5 p.

Research output: Contribution to journal › Article

Regulation of the cardiac Na(+) pump by palmitoylation of its catalytic and regulatory subunits

Howie, J., Tulloch, L. B., Shattock, M. J. & Fuller, W. 2013 In : Biochemical Society Transactions. 41, 1, p. 95-100, 6 p.

Research output: Contribution to journal › Article

Seven years' experience of Mohs micrographic surgery in a UK centre, and development of a UK minimum dataset and audit standards

MacFarlane, L., Waters, A., Evans, A., Affleck, A. & Fleming, C. 2013 In : Clinical and Experimental Dermatology. 38, 3, p. 262-269, 8 p.

Research output: Contribution to journal › Article

The manufacture and assessment of tissue microarrays: suggestions and criteria for analysis, with breast cancer as an example

Pinder, S. E., Brown, J. P., Gillett, C., Purdie, C., Speirs, V., Thompson, A. M., Shaaban, A. M. & NCRI Breast Clinical Studies Grp 2013 In : Journal of Clinical Pathology. 66, 3, p. 169-177, 9 p.

Research output: Contribution to journal › Article

The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow

Lek, H. S., Morrison, V. L., Conneely, M., Campbell, P. A., McGloin, D., Kliche, S., Watts, C., Prescott, A. & Fagerholm, S. C. 2013 In : Journal of Biological Chemistry.

Research output: Contribution to journal › Article

Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1–PP2A protein complex

Krauss, S., Griesche, N., Jastrzebska, E., Chen, C., Rutschow, D., Achmuller, C., Dorn, S., Boesch, S. M., Lalowski, M., Wanker, E., Schneider, R. & Schweiger, S. 2013 In : Nature Communications. 4, 1511

Research output: Contribution to journal › Article

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8 T cells

Finlay, D. K., Rosenzweig, E., Sinclair, L. V., Feijoo-Carnero, C., Hukelmann, J. L., Rolf, J., Panteleyev, A. A., Okkenhaug, K. & Cantrell, D. A. 17-Dec-2012 In : Journal of Experimental Medicine. 209, 13, p. 2441-2453, 13 p.

Research output: Contribution to journal › Article

Selective sampling using confocal Raman spectroscopy provides enhanced specificity for urinary bladder cancer diagnosis

Barman, I., Dingari, N. C., Singh, G. P., Kumar, R., Lang, S. & Nabi, G. 1-Dec-2012 In : Analytical and Bioanalytical Chemistry. 404, 10, p. 3091-3099, 9 p.

Research output: Contribution to journal › Article

2-APB-potentiated channels amplify CatSper-induced Ca signals in human sperm

Lefièvre, L., Nash, K., Mansell, S., Costello, S., Punt, E., Correia, J., Morris, J., Kirkman-Brown, J., Wilson, S. M., Barratt, C. L. R. & Publicover, S. Dec-2012 In : Biochemical Journal. 448, 2, p. 189-200, 12 p.

Research output: Contribution to journal › Article

High throughput targeted gene sequencing in 738 Myelodysplastic Syndromes patients reveals novel oncogenic genes, rare driver mutations and complex molecular signatures with potential impact for patient diagnosis and prognosis in the clinic

Papaemmanuil, E., Gerstung, M., Malcovati, L., Tauro, S., Gundem, G., Van Loo, P., Pellagatti, A., Groves, M. J., Cross, N. C. P., Gambacorti-Passerini, C., Green, A. R., Boultwood, J., Vyas, P., Hellstrom-Lindberg, E., Bowen, D., Cazzola, M., Stratton, M. R. & Campbell, P. 16-Nov-2012 In : Blood. 120, 21, 2 p., LBA-5

Research output: Contribution to journal › Meeting abstract

Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma

Pohler, E. , Mamai, O. , Hirst, J. , Zamiri, M. , Horn, H. , Nomura, T. , Irvine, A. D. , Moran, B. , Wilson, N. J. , Smith, F. J. D. , Goh, C. S. M. , Sandilands, A. , Cole, C. , Barton, G. J. , Evans, A. T. , Shimizu, H. , Akiyama, M. , Suehiro, M. , Konohana, I. , Shboul, M. & 12 others Teissier, S., Boussofara, L., Denguezli, M., Saad, A., Gribaa, M., Dopping-Hepenstal, P. J., McGrath, J. A., Brown, S. J., Goudie, D. R., Reversade, B., Munro, C. S. & McLean, W. H. I. Nov-2012 In : Nature Genetics. 44, 11, p. 1272-1276, 5 p.

Research output: Contribution to journal › Article

Revised international prognostic scoring system for myelodysplastic syndromes

Greenberg, P. L. , Tuechler, H. , Schanz, J. , Sanz, G. , Garcia-Manero, G. , Solé, F. , Bennett, J. M. , Bowen, D. , Fenaux, P. , Dreyfus, F. , Kantarjian, H. , Kuendgen, A. , Levis, A. , Malcovati, L. , Cazzola, M. , Cermak, J. , Fonatsch, C. , Le Beau, M. M. , Slovak, M. L. , Krieger, O. & 14 others Luebbert, M., Maciejewski, J., Magalhaes, S. M. M., Miyazaki, Y., Pfeilstöcker, M., Sekeres, M., Sperr, W. R., Stauder, R., Tauro, S., Valent, P., Vallespi, T., Van De Loosdrecht, A. A., Germing, U. & Haase, D. 20-Sep-2012 In : Blood. 120, 12, p. 2454-2465, 12 p.

Research output: Contribution to journal › Article

Chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer

Bruce, J., Thornton, A. J., Scott, N. W., Marfizo, S., Powell, R., Johnston, M., Wells, M., Heys, S. D. & Thompson, A. M. 4-Sep-2012 In : British Journal of Cancer. 107, p. 937-946, 10 p.

Research output: Contribution to journal › Article

Development of lentiviral gene therapy for type VII collagen deficient epidermolysis bullosa

Georgiadis, C., Thrasher, A., South, A. P., McGrath, J., Qasim, W. & Di, W. Sep-2012 In : Journal of Investigative Dermatology. 132, p. S96-S96, 1 p.

Research output: Contribution to journal › Meeting abstract

Exome level sequencing identifies candidate genes mutated in cutaneous squamous cell carcinoma progression

South, A. P., Purdie, K. J., Watt, S. A., Harwood, C. A., Proby, C. & Leigh, I. M. Sep-2012 In : Journal of Investigative Dermatology. 132, p. S37-S37, 1 p.

Research output: Contribution to journal › Meeting abstract

Expression of activated NOTCH1 induces terminal differentiation in squamous cell carcinoma keratinocytes

Robinson, K. S., Purdie, K. J., Cho, R. J., Aster, J. C., Leigh, I. M. & South, A. P. Sep-2012 In : Journal of Investigative Dermatology. 132, p. S40-S40, 1 p.

Research output: Contribution to journal › Meeting abstract

Impact Assessment of Energy Saving Lamps on Photosensitive Skin

Fenton, L., Ferguson, J., Ibbotson, S. & Moseley, H. Sep-2012 In : Journal of Investigative Dermatology. 132, p. S122-S122, 1 p.

Research output: Contribution to journal › Meeting abstract

Phaeochromocytomas associated with PTEN mutation demonstarate tissue specificity in the anti-tumour effect of mTOR inhibition

Taggart, C. & Fleming, S. Sep-2012 In : Journal of Pathology. 228, Suppl. 1, p. S37-S37, 1 p.

Research output: Contribution to journal › Meeting abstract

Photodynamic therapy and immunosuppression

Ibbotson, S. H. Sep-2012 In : British Journal of Dermatology. 167, 3, p. 465-467, 3 p.

Research output: Contribution to journal › Editorial

Diabetes, Metformin, and Breast Cancer: Lilac Time?

Goodwin, P. J., Thompson, A. M. & Stambolic, V. 10-Aug-2012 In : Journal of Clinical Oncology. 30, 23, p. 2812-2814, 3 p.

Research output: Contribution to journal › Editorial

Assessing physicians' preferences on skin cancer treatment in Europe

Ferrandiz, L., Ruiz-de-Casas, A., Trakatelli, M., de Vries, E., Ulrich, M., Aquilina, S., Saksela, O., Majewski, S., Ranki, A., Proby, C., Magnoni, C., Pitkanen, S., Kalokasidis, K., Siskou, S., Hinrichs, B., Altsitsiadis, E., Stockfleth, E., Moreno-Ramirez, D. & EPIDERM Grp Aug-2012 In : British Journal of Dermatology. 167, p. 29-35, 7 p.

Research output: Contribution to journal › Article

Influenza A viruses control expression of proviral human p53 isoforms p53β and Delta133p53α

Terrier, O., Marcel, V., Cartet, G., Lane, D. P., Lina, B., Rosa-Calatrava, M. & Bourdon, J-C. Aug-2012 In : Journal of Virology. 86, 16, p. 8452-8460, 9 p.

Research output: Contribution to journal › Article

Known and potential new risk factors for skin cancer in European populations: a multicentre case-control study

de Vries, E. , Trakatelli, M. , Kalabalikis, D. , Ferrandiz, L. , Ruiz-de-Casas, A. , Moreno-Ramirez, D. , Sotiriadis, D. , Ioannides, D. , Aquilina, S. , Apap, C. , Micallef, R. , Scerri, L. , Ulrich, M. , Pitkanen, S. , Saksela, O. , Altsitsiadis, E. , Hinrichs, B. , Magnoni, C. , Fiorentini, C. , Majewski, S. & 4 others Ranki, A., Stockfleth, E., Proby, C. & EPIDERM Grp Aug-2012 In : British Journal of Dermatology. 167, p. 1-13, 13 p.

Research output: Contribution to journal › Article

Risk factors for actinic keratosis in eight European centres: a case-control study

Traianou, A. , Ulrich, M. , Apalla, Z. , De Vries, E. , Bakirtzi, K. , Kalabalikis, D. , Ferrandiz, L. , Ruiz-de-Casas, A. , Moreno-Ramirez, D. , Sotiriadis, D. , Ioannides, D. , Aquilina, S. , Apap, C. , Micallef, R. , Scerri, L. , Pitkanen, S. , Saksela, O. , Altsitsiadis, E. , Hinrichs, B. , Magnoni, C. & 7 others Fiorentini, C., Majewski, S., Ranki, A., Proby, C. M., Stockfleth, E., Trakatelli, M. & EPIDERM Grp Aug-2012 In : British Journal of Dermatology. 167, p. 36-42, 7 p.

Research output: Contribution to journal › Article

Sentinel node biopsy in breast cancer has a greater node positivity rate than axillary node sample: results from a retrospective analysis

Macaskill, E. J., Dewar, S., Purdie, C. A., Brauer, K., Baker, L. & Brown, D. C. Aug-2012 In : European Journal of Surgical Oncology. 38, 8, p. 662-669, 8 p.

Research output: Contribution to journal › Article

ARNT controls the expression of epidermal differentiation genes through HDAC- and EGFR-dependent pathways

Robertson, E. D., Weir, L., Romanowska, M., Leigh, I. M. & Panteleyev, A. A. 15-Jul-2012 In : Journal of Cell Science. 125, 14, p. 3320-3332, 13 p.

Research output: Contribution to journal › Article

Current patch test results with the European baseline series and extensions to it from the European Surveillance System on Contact Allergy' network, 2007-2008

Uter, W. , Aberer, W. , Carlos Armario-Hita, J. , Fernandez-Vozmediano, J. M. , Ayala, F. , Balato, A. , Bauer, A. , Ballmer-Weber, B. , Beliauskiene, A. , Fortina, A. B. , Bircher, A. , Brasch, J. , Chowdhury, M. M. U. , Coenraads, P-J. , Schuttelaar, M-L. , Cooper, S. , Czarnecka-Operacz, M. , Zmudzinska, M. , Elsner, P. , English, J. S. C. & 30 others Frosch, P. J., Fuchs, T., Garcia-Gavin, J., Fernandez-Redondo, V., Gawkrodger, D. J., Gimenez-Arnau, A., Green, C. M., Horne, H. L., Johansen, J. D., Jolanki, R., Pesonen, M., King, C. M., Krecisz, B., Chomiczewska, D., Kiec-Swierczynska, M., Larese, F., Mahler, V., Ormerod, A. D., Peserico, A., Rantanen, T., Rustemeyer, T., Sanchez-Perez, J., Sansom, J. E., Silvestre, J. F., Simon, D., Spiewak, R., Statham, B. N., Stone, N., Wilkinson, M. & Schnuch, A. Jul-2012 In : Contact Dermatitis. 67, 1, p. 9-19, 11 p.

Research output: Contribution to journal › Article

Impact of the revised (2008) EORTC/MSG definitions for invasive fungal disease on the rates of diagnosis of invasive aspergillosis

Tsitsikas, D. A., Morin, A., Araf, S., Murtagh, B., Johnson, G., Vinnicombe, S., Ellis, S., Suaris, T., Wilks, M., Doffman, S. & Agrawal, S. G. Jul-2012 In : Medical Mycology : Official Publication of the International Society for Human and Animal Mycology. 50, 5, p. 538-42, 5 p.

Research output: Contribution to journal › Article

Influence of the nuclear membrane, active transport, and cell shape on the Hes1 and p53-Mdm2 pathways: insights from spatio-temporal modelling

Sturrock, M., Terry, A. J., Xirodimas, D. P., Thompson, A. M. & Chaplain, M. A. J. Jul-2012 In : Bulletin of Mathematical Biology. 74, 7, p. 1531-1579, 49 p.

Research output: Contribution to journal › Article

Quantitative analysis of cardiac left ventricular variables obtained by MRI at 3 T: a pre- and post-contrast comparison

Matthew, S., Gandy, S. J., Nicholas, R. S., Waugh, S. A., Crowe, E. A., Lerski, R. A., Dunn, M. H. & Houston, J. G. Jul-2012 In : British Journal of Radiology. 85, 1015, p. E343-E347, 5 p.

Research output: Contribution to journal › Article

The DSPII splice variant is crucial for desmosome-mediated adhesion in HaCaT keratinocytes

Cabral, R. M., Tattersall, D., Patel, V., McPhail, G. D., Hatzimasoura, E., Abrams, D. J., South, A. P. & Kelsell, D. P. 15-Jun-2012 In : Journal of Cell Science. 125, 12, p. 2853-2861, 9 p.

Research output: Contribution to journal › Article

A comparative biomarker study of 514 matched cases of male and female breast cancer reveals gender-specific biological differences

Shaaban, A. M. , Brannan, R. A. , Reall, G. , Verghese, E. T. , Hanby, A. M. , Ball, G. R. , Honarpisheh, H. , Maraqa, L. , Pollock, S. , Speirs, V. , Cserni, G. , Di Benedetto, A. , Mottolese, M. , Dent, J. , Fulford, L. , Jordan, L. , Quinlan, P. R. , Jones, J. L. , Kanthan, R. , Litwiniuk, M. & 4 others Provenzano, E., Shousha, S., Stephens, M. & Walker, R. A. 1-Jun-2012 In : Breast Cancer Research and Treatment. 133, 3, p. 949-958, 10 p.

Research output: Contribution to journal › Article

Chloride channels join the sperm 'channelome'

Publicover, S. J. & Barratt, C. L. R. Jun-2012 In : Journal of Physiology. 590, 11, p. 2553-2554, 2 p.

Research output: Contribution to journal › Article

Complete response in a melanoma patient treated with imatinib

Brown, M. C. & Casasola, R. J. Jun-2012 In : Journal of Laryngology and Otology. 126, 6, p. 638-640, 3 p.

Research output: Contribution to journal › Article

Epidemiology of an Neisseria gonorrhoeae outbreak in a low prevalence area

Shone, J., Cunningham, C., Orange, G., Eastick, K., Yirrell, D. & Allstaff, S. Jun-2012 In : Sexually Transmitted Infections. 88, Suppl.1, p. A35-A35, 1 p.

Research output: Contribution to journal › Meeting abstract

Invasive breast cancer: relationship between shear-wave elastographic findings and histologic prognostic factors

Evans, A., Whelehan, P., Thomson, K., McLean, D., Brauer, K., Purdie, C., Baker, L., Jordan, L., Rauchhaus, P. & Thompson, A. Jun-2012 In : Radiology. 263, 3, p. 673-677, 5 p.

Research output: Contribution to journal › Article

Neisseria gonorrhoeae ST26: emergence of an MSM associated strain within a heterosexual population during an outbreak

Shone, J., Orange, G., Allstaff, S., Cunningham, C., Yirrell, D. & Eastick, K. Jun-2012 In : Sexually Transmitted Infections. 88, Suppl.1, p. A33-A33, 1 p.

Research output: Contribution to journal › Meeting abstract

p63 transcriptionally regulates BNC1, a Pol I and Pol II transcription factor that regulates ribosomal biogenesis and epithelial differentiation

Boldrup, L., Coates, P. J., Laurell, G. & Nylander, K. Jun-2012 In : European Journal of Cancer. 48, 9, p. 1401-1406, 6 p.

Research output: Contribution to journal › Article

Pathways analysis in kidney cancer using proteomics approach

Zakikhani, M., Atrih, A., Lamont, S. R., Goodman, C., Fleming, I. N. & Nabi, G. Jun-2012 In : BJU International. 109, p. 24-24, 1 p.

Research output: Contribution to journal › Special issue

An evaluation of small-molecule p53 activators as chemoprotectants ameliorating adverse effects of anticancer drugs in normal cells

van Leeuwen, I. M. M., Rao, B., Sachweh, M. C. C. & Lain, S. 1-May-2012 In : Cell Cycle. 11, 9, p. 1851-1861, 11 p.

Research output: Contribution to journal › Article

In vivo interactions between ionizing radiation, inflammation and chemical carcinogens identified by increased DNA damage responses

McAllister, K. A., Lorimore, S. A., Wright, E. G. & Coates, P. J. 1-May-2012 In : Radiation Research. 177, 5, p. 584-593, 10 p.

Research output: Contribution to journal › Article

A European multicentre photopatch test study: The European Multicentre Photopatch Test Study (EMCPPTS) taskforce

Kerr, A. C. , Ferguson, J. , Haylett, A. K. , Rhodes, L. E. , Adamski, H. , Alomar, A. , Serra, E. , Antoniou, C. , Aubin, F. , Vigan, M. , Biedermann, T. , Fischer, J. , Bourrain, J-L. , Bruynzeel, D. , Rustemeyer, T. , Carrascosa, J. M. , Chowdhury, M. M. U. , de la Cuadra, J. , Foti, C. , Gardeazabal, J. & 22 others Gawkrodger, D. J., Gimenez-Arnau, A., Goncalo, M., Goossens, A., Ibbotson, S. H., Dawe, R. S., Lecha, M., Marguery, M-C., Neumann, N. J., Niklasson, B., Peyron, J-L., Pigatto, P., Spiewak, R., Stone, N., Tanew, A., Thomas, P., Bonnevalle, A., Wilkinson, S. M., Wolf, P., Gruber-Wackernagel, A., Wulf, H. C. & European Multictr Photopatch Test May-2012 In : British Journal of Dermatology. 166, 5, p. 1002-1009, 8 p.

Research output: Contribution to journal › Article

Axillary lymph node core biopsy for breast cancer metastases - How many needle passes are enough?

Macaskill, E. J., Purdie, C. A., Jordan, L. B., Mclean, D., Whelehan, P., Brown, D. C. & Evans, A. May-2012 In : Clinical Radiology. 67, 5, p. 417-419, 3 p.

Research output: Contribution to journal › Article

Dermal matrix composition promotes development of aggressive squamous cell carcinoma in recessive dystrophic epidermolysis bullosa

Ng, Y., Pourreyron, C., Salas-Alanis, J., Cepeda-Valdes, R., Yan, W., Wright, S., Chen, M., Hogg, F., McGrath, J., Murrell, D., Leigh, I., Lane, E. & South, A. May-2012 In : Journal of Investigative Dermatology. 132, p. S20-S20, 1 p.

Research output: Contribution to journal › Article

Next-generation sequencing identifies Notch receptors as integral tumor suppressors in cutaneous and lung squamous cell carcinomas

Wang, N. J. , Sanborn, Z. , Arnett, K. L. , Bayston, L. J. , Liao, W. , Proby, C. M. , Leigh, I. M. , Gordon, P. B. , Sharma, M. , North, J. P. , Vemula, S. S. , Mauro, T. M. , Neuhaus, I. M. , LeBoit, P. E. , Kwok, P. , Arron, S. T. , Bale, A. E. , Haussler, D. , Cleaver, J. E. , Gray, J. W. & 5 others Spellman, P. T., South, A. P., Aster, J. C., Blacklow, S. C. & Cho, R. J. May-2012 In : Journal of Investigative Dermatology. 132, p. S23-S23, 1 p.

Research output: Contribution to journal › Article

Skin-targeted inhibition of PPAR β/δ by selective antagonists to treat PPAR β/δ-mediated psoriasis-like skin disease in vivo

Hack, K., Reilly, L., Palmer, C., Read, K., Norval, S., Kime, R., Booth, K. & Foerster, J. May-2012 In : PLoS ONE. 7, 5

Research output: Contribution to journal › Article

Milking the stroma in triple-negative breast cancer

Thompson, A. M. & Newman, T. J. 15-Apr-2012 In : Cell Cycle. 11, 8, p. 1487-1487, 1 p.

Research output: Contribution to journal › Comment/debate

The p53 isoforms are differentially modified by Mdm2

Camus, S., Menendez, S., Fernandes, K., Kua, N., Liu, G., Xirodimas, D. P., Lane, D. P. & Bourdon, J-C. 15-Apr-2012 In : Cell Cycle. 11, 8, p. 1646-1655, 10 p.

Research output: Contribution to journal › Article

Sperm are promiscuous and CatSper is to blame...

Barratt, C. L. R. & Publicover, S. J. 4-Apr-2012 In : EMBO Journal. 31, 7, p. 1624-1626, 3 p.

Research output: Contribution to journal › Article

Charged particles in radiotherapy: A 5-year update of a systematic review

De Ruysscher, D., Pijls-Johannesma, M., Mark Lodge, M., Jones, B., Brada, M., Munro, A. & Jefferson, T. 1-Apr-2012 In : Radiotherapy and Oncology. 103, 1, p. 5-7, 3 p.

Research output: Contribution to journal › Article

Involved anterior margins after breast conserving surgery: is re-excision required?

Mullen, R., MacAskill, E. J., Khalil, A., Elseedawy, E., Brown, D. C., Lee, A. C., Purdie, C. A., Jordan, L. B. & Thompson, A. M. 1-Apr-2012 In : European Journal of Surgical Oncology. 38, 4, p. 302-306, 5 p.

Research output: Contribution to journal › Article

A quantitative molecular diagnostic system for predicting progression of vulval intraepithelial neoplasia to invasive squamous cell carcinoma

Purdie, K., Gibbon, K., Proby, C., Leigh, I., Harwood, C. & Teh, T. Apr-2012 In : British Journal of Dermatology. 166, 4, p. e29-e29, 1 p., P-1

Research output: Contribution to journal › Article

Chondroitin sulfate N-acetylgalactosaminyltransferase-1 (CSGalNAcT-1) involved in chondroitin sulfate initiation: Impact of sulfation on activity and specificity

Gulberti, S., Jacquinet, J-C., Chabel, M., Ramalanjaona, N., Magdalou, J., Netter, P., Coughtrie, M. W. H., Ouzzine, M. & Fournel-Gigleux, S. Apr-2012 In : Glycobiology. 22, 4, p. 561-571, 11 p.

Research output: Contribution to journal › Article

Effect of a synbiotic on microbial community structure in a continuous culture model of the gastric microbiota in enteral nutrition patients

Smith, A. R., Macfarlane, G. T., Reynolds, N., O'May, G. A., Bahrami, B. & Macfarlane, S. Apr-2012 In : FEMS Microbiology Ecology. 80, 1, p. 135-145, 11 p.

Research output: Contribution to journal › Article

How genetically heterogeneous is Kabuki syndrome?: MLL2 testing in 116 patients, review and analyses of mutation and phenotypic spectrum

Banka, S. , Veeramachaneni, R. , Reardon, W. , Howard, E. , Bunstone, S. , Ragge, N. , Parker, M. J. , Crow, Y. J. , Kerr, B. , Kingston, H. , Metcalfe, K. , Chandler, K. , Magee, A. , Stewart, F. , McConnell, V. P. M. , Donnelly, D. E. , Berland, S. , Houge, G. , Morton, J. E. , Oley, C. & 32 others Revencu, N., Park, S-M., Davies, S. J., Fry, A. E., Lynch, S. A., Gill, H., Schweiger, S., Lam, W. W. K., Tolmie, J., Mohammed, S. N., Hobson, E., Smith, A., Blyth, M., Bennett, C., Vasudevan, P. C., Garcia-Minaur, S., Henderson, A., Goodship, J., Wright, M. J., Fisher, R., Gibbons, R., Price, S. M., de Silva, D. C., Temple, I. K., Collins, A. L., Lachlan, K., Elmslie, F., McEntagart, M., Castle, B., Clayton-Smith, J., Black, G. C. & Donnai, D. Apr-2012 In : European Journal of Human Genetics. 20, 4, p. 381-388, 8 p.

Research output: Contribution to journal › Article

Methylation profiling of cutaneous squamous cell carcinoma reveals an embryonic stem cell signature among differentially methylated genes

Mladkova, N., McHugh, A., Rakyan, V., Proby, C. & Harwood, C. Apr-2012 In : British Journal of Dermatology. 166, 4, p. e23-e23, 1 p., O-21

Research output: Contribution to journal › Article

Pharmacokinetics, Metabolism, Biodistribution, Radiation Dosimetry, and Toxicology of F-18-Fluoroacetate (F-18-FACE) in Non-human Primates

Nishii, R., Tong, W., Wendt, R., Soghomonyan, S., Mukhopadhyay, U., Balatoni, J., Mawlawi, O., Bidaut, L., Tinkey, P., Borne, A., Alauddin, M., Gonzalez-Lepera, C., Yang, B. & Gelovani, J. G. Apr-2012 In : Molecular Imaging and Biology. 14, 2, p. 213-224, 12 p.

Research output: Contribution to journal › Article

Prevalence and predictors of low vitamin D status in patients referred to a tertiary photodiagnostic service: a retrospective study

Reid, S. M., Robinson, M., Kerr, A. C. & Ibbotson, S. H. Apr-2012 In : Photodermatology, Photoimmunology & Photomedicine. 28, 2, p. 91-96, 6 p.

Research output: Contribution to journal › Article

Regulation of the cardiac sodium pump

Fuller, W., Tulloch, L. B., Howie, J., Wypijewski, K. J., Shattock, M. J. & Calaghan, S. C. Apr-2012 In : Cellular and Molecular Life Sciences. 70, 8, p. 1357-1380, 24 p.

Research output: Contribution to journal › Article

RHBDF2 mutations affect epidermal growth factor signalling in tylosis with oesophageal cancer

Etheridge, S., Blaydon, D., Brooke, M., Risk, J., South, A. & Kelsell, D. Apr-2012 In : British Journal of Dermatology. 166, 4, p. e24-e25, 2 p., O-24

Research output: Contribution to journal › Article

RNAi depletion of PRSS21 induces apoptosis in cutaneous squamous cell carcinoma keratinocytes

Robinson, K., Watt, S., Leigh, I. & South, A. Apr-2012 In : British Journal of Dermatology. 166, 4, p. e25-e25, 1 p., O-25

Research output: Contribution to journal › Article

Role of non-surgical therapies in the management of periocular basal cell carcinoma and squamous intra-epidermal carcinoma: a case series and review of the literature

Attili, S. K., Ibbotson, S. H. & Fleming, C. Apr-2012 In : Photodermatology, Photoimmunology & Photomedicine. 28, 2, p. 68-79, 12 p.

Research output: Contribution to journal › Article

The importance of nonpharmacogenetic factors in endocrine therapy

McCowan, C. & Thompson, A. M. Apr-2012 In : Pharmacogenomics. 13, 6, p. 721-728, 8 p.

Research output: Contribution to journal › Scientific review

Ultraviolet A1 phototherapy: a British Photodermatology Group workshop report

Kerr, A. C., Ferguson, J., Attili, S. K., Beattie, P. E., Coleman, A. J., Dawe, R. S., Eberlein, B., Goulden, V., Ibbotson, S. H., Menage, H. . P., Moseley, H., Novakovic, L., Walker, S. L., Woods, J. A., Young, A. R. & Sarkany, R. P. E. Apr-2012 In : Clinical and Experimental Dermatology. 37, 3, p. 219-226, 8 p.

Research output: Contribution to journal › Article