Pharmacology & Neuroscience

5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside acutely stimulates skeletal muscle 2-deoxyglucose uptake in healthy men

Cuthbertson, D. J., Babraj, J. A., Mustard, K. J. W., Towler, M. C., Green, K. A., Wackerhage, H., Leese, G. P., Baar, K., Thomason-Hughes, M., Sutherland, C., Hardie, D. G. & Rennie, M. J. 2007 In : Diabetes. 56, 8, p. 2078-2084, 7 p.

Research output: Contribution to journal › Article

5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase

Lochhead, P. A., Salt, I. P., Walker, K. S., Hardie, D. G. & Sutherland, C. 2000 In : Diabetes. 49, 6, p. 896-903, 8 p.

Research output: Contribution to journal › Article

5-ht inhibition of rat insulin 2 promoter cre recombinase transgene and proopiomelanocortin neuron excitability in the mouse arcuate nucleus

Hisadome, K., Smith, M. A., Choudhury, A. I., Claret, M., Withers, D. J. & Ashford, M. L. J. 3-Mar-2009 In : Neuroscience. 159, 1, p. 83-93, 11 p.

Research output: Contribution to journal › Article

A cytoplasmic region determines single-channel conductance in 5-HT3 receptors

Kelley, S. P., Dunlop, J. I., Kirkness, E. F., Lambert, J. J. & Peters, J. A. Jul-2003 In : Nature. 424, 6946, p. 321-324, 4 p.

Research output: Contribution to journal › Article

A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic β-cells

Ning, K., Miller, L. C., Laidlaw, H. A., Burgess, L. A., Perera, N. M., Downes, C. P., Leslie, N. R. & Ashford, M. L. J. Jun-2006 In : The EMBO Journal. 25, 11, p. 2377-2387, 11 p.

Research output: Contribution to journal › Article

A novel regulation of IRS1 (insulin receptor substrate-1) expression following short term insulin administration

Ruiz-Alcaraz, A. J., Liu, H-K., Cuthbertson, D. J., McManus, E. J., Akhtar, S., Lipina, C., Morris, A. D., Petrie, J. R., Hundal, H. S. & Sutherland, C. 1-Dec-2005 In : Biochemical Journal. 392, p. 345-352, 8 p.

Research output: Contribution to journal › Article

A simple method for sequencing small DNAs by introducing precise overlapping ends into restriction digestion fragments

Rena, G. & Houslay, M. D. 1998 In : Nucleic Acids Research. 26, 16, p. 3867-3868, 2 p.

Research output: Contribution to journal › Article

A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABAA receptors

Jensen, M. L., Wafford, K. A., Brown, A. R., Belelli, D., Lambert, J. J. & Mirza, N. R. 2013 In : British Journal of Pharmacology. 168, 5, p. 1118-1132, 15 p.

Research output: Contribution to journal › Article

A temporal switch in the insulin-signalling pathway that regulates hepatic IGF-binding protein-1 gene expression

Finlay, D., Ruiz-Alcaraz, A. J., Lipina, C., Perrier, S. & Sutherland, C. Oct-2006 In : Journal of Molecular Endocrinology. 37, 2, p. 227-237, 11 p.

Research output: Contribution to journal › Article

Activation of hypothalamic ATP-sensitive K⁺ channels by the aminoguanidine carboxylate BVT.12777

Mirshamsi, S., Laidlaw, H. A., Spanswick, D. & Ashford, M. L. J. Apr-2005 In : Journal of Neuroendocrinology. 17, 4, p. 246-254, 9 p.

Research output: Contribution to journal › Article