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Pharmacology & Neuroscience

  1. Intracellular ATP Influences Synaptic Plasticity in Area CA1 of Rat Hippocampus via Metabolism to Adenosine and Activity-Dependent Activation of Adenosine A(1) Receptors

    zur Nedden, S., Hawley, S., Pentland, N., Hardie, D. G., Doney, A. S. & Frenguelli, B. 20 Apr 2011 In : Journal of Neuroscience. 31, 16, p. 6221-6234 14 p.

    Research output: Contribution to journalArticle

  2. Deletion of Lkb1 in Pro-Opiomelanocortin Neurons Impairs Peripheral Glucose Homeostasis in Mice

    Claret, M. , Smith, M. A. , Knauf, C. , Al-Qassab, H. , Woods, A. , Heslegrave, A. , Piipari, K. , Emmanuel, J. J. , Colom, A. , Valet, P. , Cani, P. D. , Begum, G. , White, A. , Mucket, P. , Peters, M. , Mizuno, K. , Batterham, R. L. , Giese, K. P. , Ashworth, A. , Burcelin, R. & 3 others Ashford, M. L., Carling, D. & Withers, D. J. Mar 2011 In : Diabetes. 60, 3, p. 735-745 11 p.

    Research output: Contribution to journalArticle

  3. CRMP2 Hyperphosphorylation is Characteristic of Alzheimer's Disease and not a Feature Common to Other Neurodegenerative Diseases

    Williamson, R., van Aalten, L., Mann, D. M. A., Platt, B., Plattner, F., Bedford, L., Mayer, J., Howlett, D., Usardi, A., Sutherland, C. & Cole, A. R. 2011 In : Journal of Alzheimer's Disease. 27, 3, p. 615-625 11 p.

    Research output: Contribution to journalArticle

  4. NMDA receptor subunit composition determines the polarity of leptin-induced synaptic plasticity

    Moult, P. R. & Harvey, J. 2011 In : Neuropharmacology. 61, 5-6, p. 924-936 13 p.

    Research output: Contribution to journalArticle

  5. What are the bona fide GSK3 substrates?

    Sutherland, C. 2011 In : International Journal of Alzheimer's Disease. 2011, p. 1-23

    Research output: Contribution to journalArticle

  6. Regulation of Tau-Dependent Toxicity by Brain Selective/SAD Kinases

    Lyn-Adams, C., Frenguelli, B., Moffat, K. & Sutherland, C. Dec 2010 In : Journal of Neurogenetics. 24, p. 12-12 1 p.

    Research output: Contribution to journalMeeting abstract

  7. Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain

    Soutar, M. P. M., Kim, W-Y., Williamson, R., Peggie, M., Hastie, C. J., McLauchlan, H., Snider, W. D., Gordon-Weeks, P. R. & Sutherland, C. Nov 2010 In : Journal of Neurochemistry. 115, 4, p. 974-983 10 p.

    Research output: Contribution to journalArticle

  8. Generation, validation and humanisation of a novel insulin resistant cell model

    Logie, L., Ruiz-Alcaraz, A. J., Schofield, C. J., Hundal, H. S., Feuerstein, G. Z., Brady, J. D., Crowther, D., Tommasi, A. M., Grierson, C. E., Shepherd, B., Morris, A. D., Hansen, M. K., Pearson, E. & Sutherland, C. 1 Oct 2010 In : Biochemical Pharmacology. 80, 7, p. 1042-1049 8 p.

    Research output: Contribution to journalArticle

  9. Loss of AMP-activated protein kinase alpha 2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia

    Beall, C., Piipari, K., Al-Qassab, H., Smith, M. A., Parker, N., Carling, D., Viollet, B., Withers, D. J. & Ashford, M. L. J. 15 Jul 2010 In : Biochemical Journal. 429, 2, p. 323-333 11 p.

    Research output: Contribution to journalArticle

  10. Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles

    Clayton, E. L., Sue, N., Smillie, K. J., O'Leary, T., Bache, N., Cheung, G., Cole, A. R., Wyllie, D. J., Sutherland, C., Robinson, P. J. & Cousin, M. A. Jul 2010 In : Nature Neuroscience. 13, 7, p. 845-U85 9 p.

    Research output: Contribution to journalArticle

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