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  1. Enhanced insulin sensitivity associated with provision of mono and polyunsaturated fatty acids in skeletal muscle cells involves counter modulation of PP2A

    Nardi, F., Lipina, C., Magill, D., Hage Hassan, R., Hajduch, E., Gray, A. & Hundal, H. S. 2014 In : PLoS ONE. 9, 3, e92255

    Research output: Contribution to journalArticle

  2. Dysfunctional astrocytic and synaptic regulation of hypothalamic glutamatergic transmission in a mouse model of early-life adversity: relevance to neurosteroids and programming of the stress-response.

    Gunn, B., Cunningham, L., Cooper, M. A., Corteen, N., Seifi, M., Swinny, J. D., Lambert, J. J. & Belelli, D. 11 Dec 2013 In : Journal of Neuroscience. 33, 50, p. 19534-19554 21 p.

    Research output: Contribution to journalArticle

  3. Prolonged inhibition of 5-HT3 receptors by palonosetron results from surface receptor inhibition rather than inducing receptor internalization

    Hothersall, J. D., Moffat, C. & Connolly, C. N. Jul 2013 In : British Journal of Pharmacology. 169, 6, p. 1252-1262 11 p.

    Research output: Contribution to journalArticle

  4. AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels

    Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J. Jun 2013 In : Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.

    Research output: Contribution to journalArticle

  5. Cholinergic pesticides cause mushroom body neuronal inactivation in honeybees

    Palmer, M. J., Moffat, C., Saranzewa, N., Harvey, J., Wright, G. A. & Connolly, C. N. 27 Mar 2013 In : Nature Communications. 4, 1634

    Research output: Contribution to journalArticle

  6. Beta-secretase 1 (BACE1) inhibition improves obese and diabetic phenotypes in a leptin dependent manner

    Meakin, P. J., Jalicy, S. M., Irvine, S. W. & Ashford, M. L. J. Mar 2013 In : Diabetic Medicine. 30, Suppl. 1, p. 41-41 1 p.P43

    Research output: Contribution to journalMeeting abstract

  7. Hormonal regulation of the Salt-inducible Kinase (SIK), a key mediator that controls hepatic gluconeogenesis

    Patel, K., Goransson, O., Sutherland, C. & Sakamoto, K. Mar 2013 In : Diabetic Medicine. 30, Suppl. 1, p. E2-E2 1 p.P577

    Research output: Contribution to journalMeeting abstract

  8. Hormonal regulation of the Salt-inducible Kinase (SIK), a key mediator that controls hepatic gluconeogenesis

    Patel, K., Goransson, O., Sutherland, C. & Sakamoto, K. Mar 2013

    Research output: Contribution to conferencePoster

  9. How does glucophage (metformin) work? Investigation of the cellular action of chemical analogues

    Logie, L., Bacon, S., Middleton, P., Harthill, J., Coats, J., Stewart, D., Sakamoto, K., McDougall, G. & Rena, G. Mar 2013 In : Diabetic Medicine. 30, Suppl. 1, p. 41-41 1 p.P44

    Research output: Contribution to journalMeeting abstract

  10. Insulin sensitising effects of monounsaturated and polyunsaturated fatty acids in skeletal muscle cells

    Nardi, F., Lipina, C., Magill, D. & Hundal, H. S. Mar 2013 In : Diabetic Medicine. 30, Suppl. 1, p. 49-49 1 p.P70

    Research output: Contribution to journalMeeting abstract

  11. Obesity-Induced Insulin Resistance in Human Skeletal Muscle Is Characterised by Defective Activation of p42/p44 MAP Kinase

    Ruiz-Alcaraz, A. J., Lipina, C., Petrie, J. R., Murphy, M. J., Morris, A. D., Sutherland, C. & Cuthbertson, D. J. 28 Feb 2013 In : PLoS ONE. 8, 2, e56928

    Research output: Contribution to journalArticle

  12. Anorexigenic and orexigenic hormone modulation of mammalian target of rapamycin complex 1 activity and the regulation of hypothalamic agouti-related protein mRNA expression

    Watterson, K. R., Bestow, D., Gallagher, J., Hamilton, D. L., Ashford, F. B., Meakin, P. J. & Ashford, M. L. J. Feb 2013 In : NeuroSignals. 21, 1-2, p. 28-41 14 p.

    Research output: Contribution to journalArticle

  13. The microsporidian parasites Nosema ceranae and Nosema apis are widespread in honeybee (Apis mellifera) colonies across Scotland

    Bollan, K. A., Hothersall, J. D., Moffat, C., Durkacz, J., Saranzewa, N., Wright, G. A., Raine, N. E., Highet, F. & Connolly, C. N. Feb 2013 In : Parasitology Research. 112, 2, p. 751-759 9 p.

    Research output: Contribution to journalArticle

  14. Leptin prevents hippocampal synaptic disruption and neuronal cell death induced by amyloid β.

    Doherty, G. H., Beccano-Kelly, D., Yan, S-D., Gunn-Moore, F. & Harvey, J. Jan 2013 In : Neurobiology of Aging. 34, 1, p. 226-37

    Research output: Contribution to journalArticle

  15. 5-chloroindole: a potent allosteric modulator of the 5-HT3 receptor

    Newman, A. . S., Batis, N., Grafton, G., Caputo, F., Brady, C. A., Lambert, J. J., Peters, J. A., Gordon, J., Barnes, N. M., Brain, K. L., Powell, A. D. & Barnes, N. M. 2013 In : British Journal of Pharmacology. 169, 6, p. 1228-1238 11 p.

    Research output: Contribution to journalArticle

  16. A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABAA receptors

    Jensen, M. L., Wafford, K. A., Brown, A. R., Belelli, D., Lambert, J. J. & Mirza, N. R. 2013 In : British Journal of Pharmacology. 168, 5, p. 1118-1132 15 p.

    Research output: Contribution to journalArticle

  17. Beta-secretase 1 (BACE1) inhibition improves obese and diabetic phenotypes in a leptin dependent manner

    Meakin, P. J., Jalicy, S. M., Irvine, S. W. & Ashford, M. L. J. 2013

    Research output: Contribution to conferencePoster

  18. How does glucophage (metformin) work? Investigation of the cellular action of chemical analogues

    Logie, L., Bacon, S., Middleton, P., Harthill, J., Coats, J., Stewart, D., Sakamoto, K., McDougall, G. & Rena, G. 2013

    Research output: Contribution to conferencePoster

  19. Insulin sensitising effects of monounsaturated and polyunsaturated fatty acids in skeletal muscle cells

    Nardi, F., Lipina, C., Magill, D. & Hundal, H. S. 2013

    Research output: Contribution to conferencePoster

  20. PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8 T cells

    Finlay, D. K., Rosenzweig, E., Sinclair, L. V., Feijoo-Carnero, C., Hukelmann, J. L., Rolf, J., Panteleyev, A. A., Okkenhaug, K. & Cantrell, D. A. 17 Dec 2012 In : Journal of Experimental Medicine. 209, 13, p. 2441-2453 13 p.

    Research output: Contribution to journalArticle

  21. Hypoglycaemia: exercise for the brain?

    Ashford, M., Beall, C. & McCrimmon, R. Oct 2012 In : Journal of Neuroendocrinology. 24, 10, p. 1365-1366 2 p.

    Research output: Contribution to journalArticle

  22. Insulin resistance in the brain: An old-age or new-age problem?

    Williamson, R., McNeilly, A. & Sutherland, C. 15 Sep 2012 In : Biochemical Pharmacology. 84, 6, p. 737-45 9 p.

    Research output: Contribution to journalArticle

  23. Mouse hypothalamic GT1-7 cells demonstrate AMPK-dependent intrinsic glucose-sensing behaviour

    Beall, C., Hamilton, D. L., Gallagher, J., Logie, L., Wright, K., Soutar, M. P., Dadak, S., Ashford, F. B., Haythorne, E., Du, Q., Jovanovic, A., McCrimmon, R. J. & Ashford, M. L. J. Sep 2012 In : Diabetologia. 55, 9, p. 2432-2444 13 p.

    Research output: Contribution to journalArticle

  24. Cannabinoid receptors in submandibular acinar cells: functional coupling between saliva fluid and electrolytes secretion and Ca2+ signalling

    Kopach, O., Vats, J., Netsyk, O., Voitenko, N., Irving, A. & Fedirko, N. 15 Apr 2012 In : Journal of Cell Science. 125, 8, p. 1884-1895 12 p.

    Research output: Contribution to journalArticle

  25. Combining Comparative Proteomics and Molecular Genetics Uncovers Regulators of Synaptic and Axonal Stability and Degeneration In Vivo

    Wishart, T. M., Rooney, T. M., Lamont, D. J., Wright, A. K., Morton, A. J., Jackson, M., Freeman, M. R. & Gillingwater, T. H. 2012 In : PLoS Genetics. 8, 8

    Research output: Contribution to journalArticle

  26. Comparison of effects of biguanide and diguanidine antihyperglycaemic drugs on cell signalling responses

    Bacon, S., Harthill, J., Coats, J., Stewart, D., McDougall, G. & Rena, G. 2012

    Research output: Contribution to conferencePoster

  27. Comparison of effects of biguanide and diguanidine antihyperglycaemic drugs on cell signalling responses

    Bacon, S., Harthill, J., Coates, J., Stewart, D., McDougall, G. & Rena, G. 2012 In : Diabetic Medicine. 29, Suppl. 1, p. 41 1 p.P41

    Research output: Contribution to journalMeeting abstract

  28. Disordered insulin secretion in the development of insulin resistance and Type 2 diabetes

    Schofield, C. J. & Sutherland, C. 2012 In : Diabetic Medicine. 29, 8, p. 972-979 8 p.

    Research output: Contribution to journalBook/Film/Article review

  29. From cannabis to the endocannabinoid system: refocussing attention on potential clinical benefits

    Youssef, F. F. & Irving, A. J. 2012 In : West Indian Medical Journal. 61, 3

    Research output: Contribution to journalArticle

  30. Identifying key knowledge needs for evidence-based conservation of wild insect pollinators: a collaborative cross-sectoral exercise

    Dicks, L. V. , Abrahams, A. , Atkinson, J. , Biesmeijer, J. , Bourn, N. , Brown, C. , Brown, M. J. F. , Carvell, C. , Connolly, C. , Cresswell, J. E. , Croft, P. , Darvill, B. , De Zylva, P. , Effingham, P. , Fountain, M. , Goggin, A. , Harding, D. , Harding, T. , Hartfield, C. , Heard, M. S. & 30 others Heathcote, R., Heaver, D., Holland, J., Howe, M., Hughes, B., Huxley, T., Kunin, W. E., Little, J., Mason, C., Memmott, J., Osborne, J., Pankhurst, T., Paxton, R. J., Pocock, M. J. O., Potts, S. G., Power, E. F., Raine, N. E., Ranelagh, E., Roberts, S., Saunders, R., Smith, K., Smith, R. M., Sutton, P., Tilley, L. A. N., Tinsley, A., Tonhasca, A., Vanbergen, A. J., Webster, S., Wilson, A. & Sutherland, W. J. 2012 In : Insect Conservation and Diversity. 6, 3, p. 435-446 12 p.

    Research output: Contribution to journalArticle

  31. MSK1 regulates homeostatic and experience-dependent synaptic plasticity

    Corrêa, S. A. L., Hunter, C. J., Palygin, O., Wauters, S. C., Martin, K. J., McKenzie, C., McKelvey, K., Morris, R. G. M., Pankratov, Y., Arthur, J. S. C. & Frenguelli, B. 2012 In : Journal of Neuroscience. 32, 38, p. 13039-13051 13 p.

    Research output: Contribution to journalArticle

  32. Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

    Chowdhry, S., Zhang, Y., McMahon, M., Sutherland, C., Cuadrado, A. & Hayes, J. D. 2012 In : Oncogene. 32, p. 3765-3781 17 p.

    Research output: Contribution to journalArticle

  33. Nrf2 orchestrates fuel partitioning for cell proliferation

    Hayes, J. D. & Ashford, M. L. J. 2012 In : Cell Metabolism. 16, 2, p. 139-141 3 p.

    Research output: Contribution to journalArticle

  34. Regulation of AMPA receptor surface trafficking and synaptic plasticity by a cognitive enhancer and antidepressant molecule

    Zhang, H., Etherington, L-A., Hafner, A-S., Belelli, D., Coussen, F., Delagrange, P., Chaouloff, F., Spedding, M., Lambert, J. J., Choquet, D. & Groc, L. 2012 In : Molecular Psychiatry. 18, p. 471-484 14 p.

    Research output: Contribution to journalArticle

  35. Effects of aldosterone and related steroids on LPS-induced increased expression of inducible NOS in rat aortic smooth muscle cells

    Godfrey, V., Martin, A. L., Struthers, A. D. & Lyles, G. A. Dec 2011 In : British Journal of Pharmacology. 164, 8, p. 2003-2014 12 p.

    Research output: Contribution to journalArticle

  36. Guide to Receptors and Channels (GRAC), 5th edition

    Alexander, S. P. H., Mathie, A. & Peters, J. Nov 2011 In : British Journal of Pharmacology. 164, p. 12 2 p.

    Research output: Contribution to journalEditorial

  37. Distinct mechanisms regulate GABA(A) receptor and gephyrin clustering at perisomatic and axo-axonic synapses on CA1 pyramidal cells

    Panzanelli, P., Gunn, B. G., Schlatter, M. C., Benke, D., Tyagarajan, S. K., Scheiffele, P., Belelli, D., Lambert, J. J., Rudolph, U. & Fritschy, J-M. 15 Oct 2011 In : Journal of Physiology. 589, 20, p. 4959-4980 22 p.

    Research output: Contribution to journalArticle

  38. Bioinformatic Prediction and Confirmation of beta-Adducin as a Novel Substrate of Glycogen Synthase Kinase 3

    Farghaian, H., Turnley, A. M., Sutherland, C. & Cole, A. R. 15 Jul 2011 In : Journal of Biological Chemistry. 286, 28, p. 25274-25283 10 p.

    Research output: Contribution to journalArticle

  39. Identification of a Proline-rich Inositol Polyphosphate 5-Phosphatase (PIPP)center dot Collapsin Response Mediator Protein 2 (CRMP2) Complex That Regulates Neurite Elongation

    Astle, M. V., Ooms, L. M., Cole, A. R., Binge, L. C., Dyson, J. M., Layton, M. J., Petratos, S., Sutherland, C. & Mitchell, C. A. 1 Jul 2011 In : Journal of Biological Chemistry. 286, 26, p. 23407-23418 12 p.

    Research output: Contribution to journalArticle

  40. Intracellular ATP Influences Synaptic Plasticity in Area CA1 of Rat Hippocampus via Metabolism to Adenosine and Activity-Dependent Activation of Adenosine A(1) Receptors

    zur Nedden, S., Hawley, S., Pentland, N., Hardie, D. G., Doney, A. S. & Frenguelli, B. 20 Apr 2011 In : Journal of Neuroscience. 31, 16, p. 6221-6234 14 p.

    Research output: Contribution to journalArticle

  41. Neuronal membranes are key to the pathogenesis of Alzheimer's disease: the role of both raft and non-raft membrane domains

    Williamson, R. & Sutherland, C. 1 Mar 2011 In : Current Alzheimer Research. 8, 2, p. 213-221 9 p.

    Research output: Contribution to journalArticle

  42. Deletion of Lkb1 in Pro-Opiomelanocortin Neurons Impairs Peripheral Glucose Homeostasis in Mice

    Ashford, M. L. & 22 others Claret, M., Smith, M. A., Knauf, C., Al-Qassab, H., Woods, A., Heslegrave, A., Piipari, K., Emmanuel, J. J., Colom, A., Valet, P., Cani, P. D., Begum, G., White, A., Mucket, P., Peters, M., Mizuno, K., Batterham, R. L., Giese, K. P., Ashworth, A., Burcelin, R., Carling, D. & Withers, D. J. Mar 2011 In : Diabetes. 60, 3, p. 735-745 11 p.

    Research output: Contribution to journalArticle

  43. CRMP2 Hyperphosphorylation is Characteristic of Alzheimer's Disease and not a Feature Common to Other Neurodegenerative Diseases

    Williamson, R., van Aalten, L., Mann, D. M. A., Platt, B., Plattner, F., Bedford, L., Mayer, J., Howlett, D., Usardi, A., Sutherland, C. & Cole, A. R. 2011 In : Journal of Alzheimer's Disease. 27, 3, p. 615-625 11 p.

    Research output: Contribution to journalArticle

  44. NMDA receptor subunit composition determines the polarity of leptin-induced synaptic plasticity

    Moult, P. R. & Harvey, J. 2011 In : Neuropharmacology. 61, 5-6, p. 924-936 13 p.

    Research output: Contribution to journalArticle

  45. What are the bona fide GSK3 substrates?

    Sutherland, C. 2011 In : International Journal of Alzheimer's Disease. 2011, p. 1-23

    Research output: Contribution to journalArticle

  46. Regulation of Tau-Dependent Toxicity by Brain Selective/SAD Kinases

    Lyn-Adams, C., Frenguelli, B., Moffat, K. & Sutherland, C. Dec 2010 In : Journal of Neurogenetics. 24, p. 12-12 1 p.

    Research output: Contribution to journalMeeting abstract

  47. Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain

    Soutar, M. P. M., Kim, W-Y., Williamson, R., Peggie, M., Hastie, C. J., McLauchlan, H., Snider, W. D., Gordon-Weeks, P. R. & Sutherland, C. Nov 2010 In : Journal of Neurochemistry. 115, 4, p. 974-983 10 p.

    Research output: Contribution to journalArticle

  48. Generation, validation and humanisation of a novel insulin resistant cell model

    Logie, L., Ruiz-Alcaraz, A. J., Schofield, C. J., Hundal, H. S., Feuerstein, G. Z., Brady, J. D., Crowther, D., Tommasi, A. M., Grierson, C. E., Shepherd, B., Morris, A. D., Hansen, M. K., Pearson, E. & Sutherland, C. 1 Oct 2010 In : Biochemical Pharmacology. 80, 7, p. 1042-1049 8 p.

    Research output: Contribution to journalArticle

  49. Loss of AMP-activated protein kinase alpha 2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia

    Beall, C., Piipari, K., Al-Qassab, H., Smith, M. A., Parker, N., Carling, D., Viollet, B., Withers, D. J. & Ashford, M. L. J. 15 Jul 2010 In : Biochemical Journal. 429, 2, p. 323-333 11 p.

    Research output: Contribution to journalArticle

  50. Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles

    Clayton, E. L., Sue, N., Smillie, K. J., O'Leary, T., Bache, N., Cheung, G., Cole, A. R., Wyllie, D. J., Sutherland, C., Robinson, P. J. & Cousin, M. A. Jul 2010 In : Nature Neuroscience. 13, 7, p. 845-U85 9 p.

    Research output: Contribution to journalArticle

  51. Key Role of AMP-Activated Protein Kinase in Pancreatic Beta Cell Glucose-Sensing and Whole Body Glucose Homeostasis

    Piipari, K., Beall, C., Al-Qassab, H., Smith, M. A., Carling, D., Viollet, B., Ashford, M. L. J. & Withers, D. J. Jun 2010 In : Endocrine Reviews. 31, 3, p. S810-S810 1 p.

    Research output: Contribution to journalBook/Film/Article review

  52. Leptin: The Missing Link in Alzheimer Disease?

    Harvey, J. May 2010 In : Clinical Chemistry. 56, 5, p. 696-697 2 p.

    Research output: Contribution to journalEditorial

  53. GSK3 beta Regulates Myelin-Dependent Axon Outgrowth Inhibition through CRMP4

    Alabed, Y. Z., Pool, M., Tone, S. O., Sutherland, C. & Fournier, A. E. 21 Apr 2010 In : Journal of Neuroscience. 30, 16, p. 5635-5643 9 p.

    Research output: Contribution to journalArticle

  54. All tangled up: tau-dependent neurodegeneration

    Lyn-Adams, C., Moffat, K., Sutherland, C. & Frenguelli, B. G. 1 Apr 2010 In : Biochemist. 32, 2, p. 10-13 4 p.

    Research output: Contribution to journalArticle

  55. Impact of the chaperone RIC-3 on the expression of human 5-HT3 receptors: role of 5-HT3 B, C, D and E subunits

    Walstab, J., Hammer, C., Lasitschka, F., Connolly, C., Rappold, G., Boenisch, H. & Niesler, B. Mar 2010 In : Naunyn-Schmiedeberg's Archives of Pharmacology. 381, p. 16-16 1 p.

    Research output: Contribution to journalBook/Film/Article review

  56. Cocaine effects on mouse incentive-learning and human addiction are linked to alpha 2 subunit-containing GABA(A) receptors

    Dixon, C. I., Morris, H. V., Breen, G., Desrivieres, S., Jugurnauth, S., Steiner, R. C., Vallada, H., Guindalini, C., Laranjeira, R., Messas, G., Rosahl, T. W., Atack, J. R., Peden, D. R., Belelli, D., Lambert, J. J., King, S. L., Schumann, G. & Stephens, D. N. 2 Feb 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 5, p. 2289-2294 6 p.

    Research output: Contribution to journalArticle

  57. Neurosteroids: Endogenous allosteric modulators of GABA receptors

    Lambert, J. J., Cooper, M. A., Simmons, R. D. J., Weir, C. J. & Belelli, D. 1 Dec 2009 In : Psychoneuroendocrinology. 34, SUPPL. 1

    Research output: Contribution to journalArticle

  58. Rapid dendritic and axonal responses to neuronal insults

    Mizielinska, S. M., Greenwood, S. M., Tummala, H. & Connolly, C. N. Dec 2009 In : Biochemical Society Transactions. 37, p. 1389-1393 5 p.

    Research output: Contribution to journalArticle

  59. Regulation of glutamate receptor trafficking by leptin

    Moult, P. R. & Harvey, J. Dec 2009 In : Biochemical Society Transactions. 37, p. 1364-1368 5 p.

    Research output: Contribution to journalArticle

  60. Dominant Role of the p110 beta Isoform of PI3K over p110 alpha in Energy Homeostasis Regulation by POMC and AgRP Neurons

    Al-Qassab, H., Smith, M. A., Irvine, E. E., Guillermet-Guibert, J., Claret, M., Choudhury, A. I., Selman, C., Piipari, K., Clements, M., Lingard, S., Chandarana, K., Bell, J. D., Barsh, G. S., Smith, A. J. H., Batterham, R. L., Ashford, M. L. J., Vanhaesebroeck, B. & Withers, D. J. 4 Nov 2009 In : Cell Metabolism. 10, 5, p. 343-354 12 p.

    Research output: Contribution to journalArticle

  61. An in vitro model for the prediction of chemical metabolism and toxicity

    Ding, S-H., Vardy, A., Elcombe, C. R. & Wolf, C. R. 28 Jul 2009 In : Toxicology. 262, 1, p. 23-23 1 p.

    Research output: Contribution to journalBook/Film/Article review

  62. Dissecting insulin signaling pathways: individualised therapeutic targets for diagnosis and treatment of insulin resistant states

    Woods, Y. L., Petrie, J. R. & Sutherland, C. 1 Jun 2009 In : Endocrine, Metabolic and Immune Disorders - Drug Targets. 9, 2, p. 187-198 12 p.

    Research output: Contribution to journalArticle

  63. Increased CRMP2 Phosphorylation is Observed in Alzheimer's Disease: Does this Tell us Anything About Disease Development?

    Soutar, M. P. M., Thornhill, P., Cole, A. R. & Sutherland, C. Jun 2009 In : Current Alzheimer Research. 6, 3, p. 269-278 10 p.

    Research output: Contribution to journalArticle

  64. Blunting of AICAR-induced human skeletal muscle glucose uptake in type 2 diabetes is dependent on age rather than diabetic status

    Babraj, J. A., Mustard, K., Sutherland, C., Towler, M. C., Chen, S., Smith, K., Green, K., Leese, G., Hardie, D. G., Rennie, M. J. & Cuthbertson, D. J. May 2009 In : American Journal of Physiology, Endocrinology and Metabolism. 296, 5, p. E1042-E1048 7 p.

    Research output: Contribution to journalArticle

  65. Leptin-dependent Phosphorylation of PTEN Mediates Actin Restructuring and Activation of ATP-sensitive K+ Channels

    Ning, K., Miller, L. C., Laidlaw, H. A., Watterson, K. R., Gallagher, J., Sutherland, C. & Ashford, M. L. J. 3 Apr 2009 In : Journal of Biological Chemistry. 284, 14, p. 9331-9340 10 p.

    Research output: Contribution to journalArticle

  66. Insulin resistance in polycystic ovary syndrome is associated with defective regulation of ERK1/2 by insulin in skeletal muscle in vivo

    Rajkhowa, M., Brett, S., Cuthbertson, D. J., Lipina, C., Ruiz-Alcaraz, A. J., Thomas, G. E., Logie, L., Petrie, J. R. & Sutherland, C. 15 Mar 2009 In : Biochemical Journal. 418, p. 665-671 7 p.

    Research output: Contribution to journalArticle

  67. 5-ht inhibition of rat insulin 2 promoter cre recombinase transgene and proopiomelanocortin neuron excitability in the mouse arcuate nucleus

    Hisadome, K., Smith, M. A., Choudhury, A. I., Claret, M., Withers, D. J. & Ashford, M. L. J. 3 Mar 2009 In : Neuroscience. 159, 1, p. 83-93 11 p.

    Research output: Contribution to journalArticle

  68. Inhibition of thalamic excitability by 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-ol: a selective role for delta-GABA(A) receptors

    Herd, M. B., Foister, N., Chandra, D., Peden, D. R., Homanics, G. E., Brown, V. J., Balfour, D. J. K., Lambert, J. J. & Belelli, D. Mar 2009 In : European Journal of Neuroscience. 29, 6, p. 1177-1187 11 p.

    Research output: Contribution to journalArticle

  69. Astrocytic adenosine kinase regulates basal synaptic adenosine levels and seizure activity but not activity-dependent adenosine release in the hippocampus

    Etherington, L-A. V., Patterson, G. E., Meechan, L., Boison, D., Irving, A. J., Dale, N. & Frenguelli, B. G. Feb 2009 In : Neuropharmacology. 56, 2, p. 429-437 9 p.

    Research output: Contribution to journalArticle

  70. Leptin reverses long-term potentiation at hippocampal CA1 synapses

    Moult, P. R., Milojkovic, B. & Harvey, J. Feb 2009 In : Journal of Neurochemistry. 108, 3, p. 685-696 12 p.

    Research output: Contribution to journalArticle

  71. Bi-directional modulation of fast inhibitory synaptic transmission by leptin

    Solovyova, N., Moult, P. R., Milojkovic, B., Lambert, J. J. & Harvey, J. Jan 2009 In : Journal of Neurochemistry. 108, 1, p. 190-201 12 p.

    Research output: Contribution to journalArticle

  72. Novel compounds selectively enhance delta subunit containing GABA(A) receptors and increase tonic currents in thalamus

    Wafford, K. A., van Niel, M. B., Ma, Q. P., Horridge, E., Herd, M. B., Peden, D. R., Belelli, D. & Lambert, J. Jan 2009 In : Neuropharmacology. 56, 1, p. 182-189 8 p.

    Research output: Contribution to journalArticle

  73. The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation

    Henstridge, C. M., Balenga, N. A. B., Ford, L. A., Ross, R. A., Waldhoer, M. & Irving, A. J. 2009 In : FASEB Journal. 23, 1, p. 183-193 11 p.

    Research output: Contribution to journalArticle

  74. The identification and characterisation of compounds with insulin-like properties

    Cameron, A. R., Harthill, J. & Rena, G. 2009 In : Diabetologia. 52, Suppl. 1, p. S203-S203 1 p.PS 29

    Research output: Contribution to journalMeeting abstract

  75. Anaesthesia generates neuronal insulin resistance by inducing hypothermia

    Holscher, C., van Aalten, L. & Sutherland, C. 9 Oct 2008 In : BMC Neuroscience. 9, p. - 7 p.100

    Research output: Contribution to journalArticle

  76. Hormonal regulation of hippocampal dendritic morphology and synaptic plasticity

    Moult, P. R. & Harvey, J. 1 Oct 2008 In : Cell Adhesion and Migration. 2, 4, p. 269-275 7 p.

    Research output: Contribution to journalArticle

  77. The orphan adapter protein SLY1 as a novel anti-apoptotic protein required for thymocyte development

    Reis, B., Finkenstaedt, D., Finlay, D. K., Cantrell, D. A., Pfeffer, K. & Beer, S. Aug 2008 In : Wiener Klinische Wochenschrift. 120, Supplement 1, p. 20-20 1 p.057

    Research output: Contribution to journalBook/Film/Article review

  78. Neuroprotective actions of leptin on central and peripheral neurons in vitro

    Doherty, G. H., Oldreive, C. & Harvey, J. 17 Jul 2008 In : Neuroscience. 154, 4, p. 1297-1307 11 p.

    Research output: Contribution to journalArticle

  79. Relative resistance of Cdk5-phosphorylated CRMP2 to dephosphorylation

    Cole, A. R., Soutar, M. P. M., Rembutsu, M., van Aalten, L., Hastie, C. J., Mclauchlan, H., Peggie, M., Balastik, M., Lu, K. P. & Sutherland, C. 27 Jun 2008 In : Journal of Biological Chemistry. 283, 26, p. 18227-18237 11 p.

    Research output: Contribution to journalArticle

  80. Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance

    Bayascas, J. R., Wullschleger, S., Sakamoto, K., Garcia-Martinez, J. M., Clacher, C., Komander, D., van Aalten, D. M. F., Boini, K. M., Lan, F., Lipina, C., Logie, L., Sutherland, C., Chudek, J. A., van Diepen, J. A., Voshol, P. J., Lucocq, J. M. & Alessi, D. R. May 2008 In : Molecular and Cellular Biology. 28, 10, p. 3258-3272 15 p.

    Research output: Contribution to journalArticle

  81. Novel procedure to investigate the effect of phosphorylation on protein complex formation in vitro and in cells

    Rembutsu, M., Soutar, M. P. M., Van Aalten, L., Gourlay, R., Hastie, C. J., McLauchlan, H., Morrice, N. A., Cole, A. R. & Sutherland, C. 19 Feb 2008 In : Biochemistry. 47, 7, p. 2153-2161 9 p.

    Research output: Contribution to journalArticle

  82. Developmental maturation of synaptic and extrasynaptic GABA(A) receptors in mouse thalamic ventrobasal neurones

    Peden, D. R., Petitjean, C. M., Herd, M. B., Durakoglugil, M. S., Rosahl, T. W., Wafford, K., Homanics, G. E., Belelli, D., Fritschy, J-M. & Lambert, J. J. 15 Feb 2008 In : Journal of Physiology. 586, 4, p. 965-987 23 p.

    Research output: Contribution to journalArticle

  83. Identification of small compounds that mimic insulin action on the transcription factor FOXO1a

    Cameron, A., Anton, S., Reetoo, N., Melville, L., Houston, N., Dayal, S., McDougall, G., Stewart, D. & Rena, G. 2008 In : Diabetes. 57, Suppl., p. A699-A700 2 p.

    Research output: Contribution to journalMeeting abstract

  84. Measuring GSK3 expression and activity in cells

    Cole, A. R. & Sutherland, C. 2008 Wnt signaling: pathway methods and mammalian models. Vincan , E. (ed.). Humana Press, p. 45-65 21 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  85. Neurosteroid modulation of GABA(A) receptors: Molecular determinants and significance in health and disease

    Mitchell, E. A., Herd, M. B., Gunn, B. G., Lambert, J. J. & Belelli, D. 2008 In : Neurochemistry International. 52, 4-5, p. 588-595 8 p.

    Research output: Contribution to journalArticle

  86. Neurotrophic effects of leptin on cerebellar Purkinje but not granule neurons in vitro

    Oldreive, C. E., Harvey, J. & Doherty, G. H. 2008 In : Neuroscience Letters. 438, 1, p. 17-21 5 p.

    Research output: Contribution to journalArticle

  87. The identification and characterisation of compounds with insulin-like properties

    Cameron, A. R., Harthill, J. & Rena, G. 2008

    Research output: Contribution to conferencePoster

  88. Trafficking of 5-HT3 and GABA(A) receptors (Review)

    Connolly, C. 2008 In : Molecular Membrane Biology. 25, 4, p. 293-301 9 p.

    Research output: Contribution to journalScientific review

  89. Dendritic and mitochondrial changes during glutamate excitotoxicity

    Greenwood, S. M. & Connolly, C. N. Dec 2007 In : Neuropharmacology. 53, 8, p. 891-898 8 p.

    Research output: Contribution to journalScientific review

  90. Leptin regulation of neuronal excitability and cognitive function

    Harvey, J. Dec 2007 In : Current Opinion in Pharmacology. 7, 6, p. 643-647 5 p.

    Research output: Contribution to journalScientific review

  91. Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression

    Cole, A. R., Noble, W., van Aalten, L., Plattner, F., Meimaridou, R., Hogan, D., Taylor, M., LaFrancois, J., Gunn-Moore, F., Verkhratsky, A., Oddo, S., LaFerla, F., Giese, K. P., Dineley, K. T., Duff, K., Richardson, J. C., Du Yan, S., Hanger, D. P., Allan, S. M. & Sutherland, C. Nov 2007 In : Journal of Neurochemistry. 103, 3, p. 1132-1144 13 p.

    Research output: Contribution to journalArticle

  92. Differential subcellular localization of RIC-3 Isoforms and their role in determining 5-HT3 receptor composition

    Cheng, A., Bollan, K. A., Greenwood, S. M., Irving, A. J. & Connolly, C. N. 7 Sep 2007 In : Journal of Biological Chemistry. 282, 36, p. 26158-26166 9 p.

    Research output: Contribution to journalArticle

  93. Mitochondrial dysfunction and dendritic beading during neuronal toxicity

    Greenwood, S. M., Mizielinska, S. M., Frenguelli, B. G., Harvey, J. & Connolly, C. N. 7 Sep 2007 In : Journal of Biological Chemistry. 282, 36, p. 26235-26244 10 p.

    Research output: Contribution to journalArticle

  94. Characterization of a protein kinase B inhibitor in vitro and in insulin-treated liver cells

    Logie, L., Ruiz-Alcaraz, A. J., Keane, M., Woods, Y. L., Bain, J., Marquez, R., Alessi, D. R. & Sutherland, C. Sep 2007 In : Diabetes. 56, 9, p. 2218-2227 10 p.

    Research output: Contribution to journalArticle

  95. GABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids

    Mitchell, E. A., Gentet, L. J., Dempster, J. & Belelli, D. Sep 2007 In : Journal of Physiology. 583, 3, p. 1021-1040 20 p.

    Research output: Contribution to journalArticle

  96. AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

    Claret, M., Smith, M. A., Batterham, R. L., Selman, C., Choudhury, A. I., Fryer, L. G. D., Clements, M., Al-Qassab, H., Heffron, H., Xu, A. W., Speakman, J. R., Barsh, G. S., Viollet, B., Vaulont, S., Ashford, M. L. J., Carling, D. & Withers, D. J. Aug 2007 In : Journal of Clinical Investigation. 117, 8, p. 2325-2336 12 p.

    Research output: Contribution to journalArticle

  97. Leptin promotes rapid dynamic changes in hippocampal dendritic morphology

    O'Malley, D., MacDonald, N., Mizielinska, S., Connolly, C. N., Irving, A. J. & Harvey, J. Aug 2007 In : Molecular and Cellular Neuroscience. 35, 4, p. 559-572 14 p.

    Research output: Contribution to journalArticle

  98. BVT.3531 reduces body weight and activates KATP channels in isolated arcuate neurons in rats

    Mirshamsi, S., Olsson, M., Arnelo, U., Kinsella, J. M., Permert, J. & Ashford, M. L. J. Jun 2007 In : Regulatory Peptides. 141, 1-3, p. 19-24 6 p.

    Research output: Contribution to journalArticle

  99. Generation and functional characterization of fluorescent, N-terminally tagged CB1 receptor chimeras for live-cell imaging

    McDonald, N. A., Henstridge, C. M., Connolly, C. N. & Irving, A. J. Jun 2007 In : Molecular and Cellular Neuroscience. 35, 2, p. 237-248 12 p.

    Research output: Contribution to journalArticle

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