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  1. Preference for detail in medical illustrations amongst professionals and laypersons

    Strong, J. & Erolin, C. Jun-2013 In : Journal of Visual Communication in Medicine. 36, 1-2, p. 38-43, 6 p.

    Research output: Contribution to journal › Article

  2. Global Quantitative SILAC Phosphoproteomics Reveals Differential Phosphorylation Is Widespread between the Procyclic and Bloodstream Form Lifecycle Stages of Trypanosoma brucei

    Urbaniak, M. D., Martin, D. M. A. & Ferguson, M. A. J. 3-May-2013 In : Journal of Proteome Research. 12, 5, p. 2233-2244, 12 p.

    Research output: Contribution to journal › Article

  3. Insights into Diphthamide, key Diphtheria Toxin effector

    Abdel-Fattah, W., Scheidt, V., Uthman, S., Stark, M. J. R. & Schaffrath, R. 3-May-2013 5, 5, p. 958-968, 11 p.

    Research output: Contribution to journal › Article

  4. Structural biology: Security measures of a master regulator

    Alessi, D. R. & Kulathu, Y. 1-May-2013 In : Nature.

    Research output: Contribution to journal › Article

  5. The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system

    Strickson, S., Campbell, D. G., Emmerich, C. H., Knebel, A., Plater, L., Ritorto, M. S., Shpiro, N. & Cohen, P. 1-May-2013 In : Biochemical Journal. 451, 3, p. 427-437, 11 p.

    Research output: Contribution to journal › Article

  6. Age estimation from radiographic images of the knee

    Hackman, L. & Black, S. May-2013 In : Journal of Forensic Sciences. 58, 3, p. 732-737, 6 p.

    Research output: Contribution to journal › Article

  7. Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

    Sinclair, L. V., Rolf, J., Emslie, E., Shi, Y-B., Taylor, P. M. & Cantrell, D. A. May-2013 In : Nature Immunology. 14, 5, p. 500-508, 9 p.

    Research output: Contribution to journal › Article

  8. Iron acquisition and allocation in stramenopile algae

    Raven, J. A. May-2013 In : Journal of Experimental Botany. 64, 8, p. 2119-2127, 9 p.

    Research output: Contribution to journal › Comment/debate

  9. Microbial responses to the erosional redistribution of soil organic carbon in arable fields.

    Dungait, J. A. J., Ghee, C., Rowan, J. S., McKenzie, B. M., Hawes, C., Dixon, E. R., Paterson, E. & Hopkins, D. W. May-2013 In : Soil Biology & Biochemistry. 60, p. 195-201, 7 p.

    Research output: Contribution to journal › Article

  10. The vascular collar of the ilium: Three-dimensional evaluation of the dominant nutrient foramen

    Cunningham, C. A. & Black, S. M. May-2013 In : Clinical Anatomy. 26, 4, p. 502-508, 7 p.

    Research output: Contribution to journal › Article

  11. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability

    Bett, J. S., Ibrahim, A. F. M., Garg, A. K., Kelly, V., Pedrioli, P., Rocha, S. & Hay, R. T. 15-Apr-2013 In : Biochemical Journal. 451, 2, p. 185-194, 10 p., BJ20130026

    Research output: Contribution to journal › Article

  12. PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development

    Venigalla, R. K. C., McGuire, V. A., Clarke, R., Patterson-Kane, J. C., Najafov, A., Toth, R., McCarthy, P. C., Simeons, F., Stojanovski, L. & Arthur, J. S. C. 3-Apr-2013 In : EMBO Journal. 32, 7, p. 1008-22, 15 p.

    Research output: Contribution to journal › Article

  13. The architecture of EssB, an integral membrane component of the type VII secretion system

    Zoltner, M., Norman, D. G., Fyfe, P. K., El Mkami, H., Palmer, T. & Hunter, W. N. 2-Apr-2013 In : Structure. 21, 4, p. 595-603, 9 p.

    Research output: Contribution to journal › Article

  14. The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction

    Ohta, A., Schumacher, F-R., Mehellou, Y., Johnson, C., Knebel, A., Macartney, T. J., Wood, N. T., Alessi, D. R. & Kurz, T. 1-Apr-2013 In : Biochemical Journal. 451, 1, p. 111-122, 12 p.

    Research output: Contribution to journal › Article

  15. AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?

    Dandapani, M. & Hardie, D. G. Apr-2013 In : Biochemical Society Transactions. 41, 2, p. 687-693, 7 p.

    Research output: Contribution to journal › Article

  16. Association Between BMI Measured Within a Year After Diagnosis of Type 2 Diabetes and Mortality

    Logue, J., Walker, J. J., Leese, G., Lindsay, R., McKnight, J., Morris, A., Philip, S., Wild, S., Sattar, N. & Scottish Diabetes Research Network Epidemiology Group Apr-2013 In : Diabetes Care. 36, 4, p. 887-893, 7 p.

    Research output: Contribution to journal › Article

  17. Correlative imaging of fluorescent proteins in resin-embedded plant material

    Bell, K., Mitchell, S., Paultre, D., Posch, M. & Oparka, K. Apr-2013 In : Plant Physiology. 161, 4, p. 1595-1603, 9 p.

    Research output: Contribution to journal › Article

  18. Editor's Choice: Evaluating the potential for adverse interactions within genetically engineered breeding stacks

    Steiner, H-Y., Halpin, C., Jez, J. M., Kough, J., Parrott, W., Underhill, L., Weber, N. & Curtis Hannah, L. Apr-2013 In : Plant Physiology. 161, 4, p. 1587-1594, 8 p.

    Research output: Contribution to journal › Article

  19. Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant

    Earnshaw, W. C. , Allshire, R. C. , Black, B. E. , Bloom, K. , Salmon, E. D. , Brinkley, B. R. , Brown, W. , Cheeseman, I. M. , Choo, K. H. A. , Copenhaver, G. P. , DeLuca, J. G. , Luger, K. , Desai, A. , Oegema, K. , Cleveland, D. W. , Diekmann, S. , Erhardt, S. , Fitzgerald-Hayes, M. , Foltz, D. , Fukagawa, T. & 37 others Gassmann, R., Maiato, H., Gerlich, D. W., Glover, D. M., Gorbsky, G. J., Harrison, S. C., Heun, P., Hirota, T., Jansen, L. E. T., Karpen, G., Kops, G. J. P. L., Lampson, M. A., Lens, S. M., Losada, A., Maddox, P. S., Margolis, R. L., Masumoto, H., McAinsh, A. D., Mellone, B. G., O'Neill, R. J., Meraldi, P., Musacchio, A., Scott, K. C., Sullivan, B. A., Straight, A. F., Stukenberg, P. T., Sullivan, K. F., Sunkel, C. E., Swedlow, J. R., Walczak, C. E., Warburton, P. E., Westermann, S., Willard, H. F., Wordeman, L., Yanagida, M., Yen, T. J. & Yoda, K. Apr-2013 In : Chromosome Research. 21, 2, p. 101-106, 6 p.

    Research output: Contribution to journal › Article

  20. Reliability and validity of genotyping filaggrin null mutations

    Margolis, D. J., Apter, A. J., Mitra, N., Gupta, J., Hoffstad, O., Papadopoulos, M., Rebbeck, T. R., MacCallum, S., Campbell, L. E., Sandilands, A. & McLean, W. H. I. Apr-2013 In : Journal of Dermatological Science. 70, 1, p. 67-68, 2 p.

    Research output: Contribution to journal › Letter

  21. Rubisco: still the most abundant protein of Earth?

    Raven, J. A. Apr-2013 In : New Phytologist. 198, 1, p. 1-3, 3 p.

    Research output: Contribution to journal › Article

  22. Test of age-related variation in the craniometry of the adult human foramen magnum region: implications for sex determination methods

    Gapert, R., Black, S. & Last, J. Apr-2013 In : Forensic Science, Medicine and Pathology. p. 1-11, 11 p.

    Research output: Contribution to journal › Article

  23. The clinical significance of calcium-signalling pathways mediating human sperm hyperactivation

    Alasmari, W., Barratt, C. L. R., Publicover, S. J., Whalley, K. M., Foster, E., Kay, V., Martins Da Silva, S. & Oxenham, S. K. Apr-2013 In : Human Reproduction. 28, 4, p. 866-876, 11 p.

    Research output: Contribution to journal › Article

  24. CSN-and CAND1-dependent remodelling of the budding yeast SCF complex

    Zemla, A., Thomas, Y., Kedziora, S., Knebel, A., Wood, N. T., Rabut, G. & Kurz, T. 27-Mar-2013 In : Nature Communications. 4, 1641

    Research output: Contribution to journal › Article

  25. Dectin-1 Regulates IL-10 Production via a MSK1/2 and CREB Dependent Pathway and Promotes the Induction of Regulatory Macrophage Markers

    Elcombe, S. E., Naqvi, S., Van den Bosch, M. W. M., MacKenzie, K. F., Cianfanelli, F., Brown, G. D. & Arthur, J. S. C. 22-Mar-2013 In : PLoS ONE. 8, 3, 15 p., e60086

    Research output: Contribution to journal › Article

  26. Topoisomerase IIα promotes activation of RNA polymerase i transcription by facilitating pre-initiation complex formation

    Ray, S., Panova, T., Miller, G., Volkov, A., Porter, A. C. G., Russell, J., Panov, K. I. & Zomerdijk, J. C. B. M. 19-Mar-2013 In : Nature Communications. 4, 1598

    Research output: Contribution to journal › Article

  27. Sialoadhesin ligand expression identifies a subpopulation of Foxp3- T cells with a distinct activation and glycosylation profile

    Kidder, D., Richards, H. E., Ziltener, H. J., Garden, O. A. & Crocker, P. R. 15-Mar-2013 In : Journal of Immunology. 190, 6, p. 2593-2602, 10 p.

    Research output: Contribution to journal › Article

  28. Siglec-E is a negative regulator of acute pulmonary neutrophil inflammation and suppresses CD11b beta2-integrin-dependent signalling

    McMillan, S. J., Sharma, R. S., McKenzie, E. J., Richards, H. E., Zhang, J., Prescott, A. & Crocker, P. R. 14-Mar-2013 In : Blood. 121, 11, p. 2084-2094, 11 p.

    Research output: Contribution to journal › Article

  29. Contributions of roots and rootstocks to sustainable, intensified crop production

    Gregory, P. J., Atkinson, C. J., Bengough, A. G., Else, M. A., Fernandez-Fernandez, F., Harrison, R. J. & Schmidt, S. Mar-2013 In : Journal of Experimental Botany. 64, 5, p. 1209-1222, 14 p.

    Research output: Contribution to journal › Scientific review

  30. Hormonal regulation of the Salt-inducible Kinase (SIK), a key mediator that controls hepatic gluconeogenesis

    Patel, K., Goransson, O., Sutherland, C. & Sakamoto, K. Mar-2013 In : Diabetic Medicine. 30, Suppl. 1, p. E2-E2, 1 p., P577

    Research output: Contribution to journal › Meeting abstract

  31. Hormonal regulation of the Salt-inducible Kinase (SIK), a key mediator that controls hepatic gluconeogenesis

    Patel, K., Goransson, O., Sutherland, C. & Sakamoto, K. Mar-2013

    Research output: Contribution to conference › Poster

  32. How does glucophage (metformin) work? Investigation of the cellular action of chemical analogues

    Logie, L., Bacon, S., Middleton, P., Harthill, J., Coats, J., Stewart, D., Sakamoto, K., McDougall, G. & Rena, G. Mar-2013 In : Diabetic Medicine. 30, Suppl. 1, p. 41-41, 1 p., P44

    Research output: Contribution to journal › Meeting abstract

  33. Identification and functional characterization of FMN2: a regulator of the cyclin-dependent kinase Inhibitor p21

    Yamada, K., Ono, M., Perkins, N. D., Rocha, S. & Lamond, A. I. Mar-2013 In : Molecular Cell. 49, 5, p. 922-933, 12 p.

    Research output: Contribution to journal › Article

  34. Insulin sensitising effects of monounsaturated and polyunsaturated fatty acids in skeletal muscle cells

    Nardi, F., Lipina, C., Magill, D. & Hundal, H. S. Mar-2013 In : Diabetic Medicine. 30, Suppl. 1, p. 49-49, 1 p., P70

    Research output: Contribution to journal › Meeting abstract

  35. Phase IIa randomized, placebo-controlled study of antimicrobial photodynamic therapy in bacterially colonized, chronic leg ulcers and diabetic foot ulcers: a new approach to antimicrobial therapy

    Morley, S., Griffiths, J., Philips, G., Moseley, H., O'Grady, C., Mellish, K., Lankester, C. L., Faris, B., Young, R. J., Brown, S. B. & Rhodes, L. E. Mar-2013 In : British Journal of Dermatology. 168, 3, p. 617-624, 8 p.

    Research output: Contribution to journal › Article

  36. Obesity-Induced Insulin Resistance in Human Skeletal Muscle Is Characterised by Defective Activation of p42/p44 MAP Kinase

    Ruiz-Alcaraz, A. J., Lipina, C., Petrie, J. R., Murphy, M. J., Morris, A. D., Sutherland, C. & Cuthbertson, D. J. 28-Feb-2013 In : PLoS ONE. 8, 2, e56928

    Research output: Contribution to journal › Article

  37. Genetic and environmental effects on Tannin composition in strawberry (Fragaria x ananassa) cultivars grown in different European locations

    Josuttis, M., Verrall, S., Stewart, D., Krueger, E. & McDougall, G. J. 30-Jan-2013 In : Journal of Agricultural and Food Chemistry. 61, 4, p. 790-800, 11 p.

    Research output: Contribution to journal › Article

  38. The importance of the N-terminus of T7 endonuclease I in the interaction with DNA junctions

    Freeman, A. D. J., Déclais, A-C. & Lilley, D. M. J. 23-Jan-2013 In : Journal of Molecular Biology. 425, 2, p. 395-410, 16 p.

    Research output: Contribution to journal › Article

  39. Metabolism of inflammation limited by AMPK and pseudo-starvation

    O'Neill, L. A. J. & Hardie, D. G. 17-Jan-2013 In : Nature. 493, 7432, p. 346-355, 10 p.

    Research output: Contribution to journal › Article

  40. Characterization of Staphylococcus aureus EssB, an integral membrane component of the Type VII secretion system: atomic resolution crystal structure of the cytoplasmic segment

    Zoltner, M., Fyfe, P. K., Palmer, T. & Hunter, W. N. 15-Jan-2013 In : Biochemical Journal. 449, 2, p. 469-477, 9 p.

    Research output: Contribution to journal › Article

  41. Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity

    Yao, C., Johnson, W. M., Gao, Y., Wang, W., Zhang, J., Deak, M., Alessi, D. R., Zhu, X., Mieyal, J. J., Roder, H., Wilson-Delfosse, A. L. & Chen, S. G. 15-Jan-2013 In : Human Molecular Genetics. 22, 2, p. 328-344, 17 p.

    Research output: Contribution to journal › Article

  42. PGE2 Induces Macrophage IL-10 Production and a Regulatory-like Phenotype via a Protein Kinase A-SIK-CRTC3 Pathway

    Mackenzie, K. F., Clark, K., Naqvi, S., McGuire, V. A., Nöehren, G., Kristariyanto, Y., van den Bosch, M., Mudaliar, M., McCarthy, P. C., Pattison, M. J., Pedrioli, P. G. A., Barton, G. J., Toth, R., Prescott, A. & Arthur, J. S. C. 15-Jan-2013 In : Journal of Immunology. 190, 2, p. 565-77, 13 p.

    Research output: Contribution to journal › Article

  43. Age estimation using foot radiographs from a modern Scottish population

    Hackman, L., Davies, C. M. & Black, S. 1-Jan-2013 In : Journal of Forensic Sciences. 58, S1, p. S146-S150, 5 p.

    Research output: Contribution to journal › Article

  44. Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6

    MacCallum, S. F., Groves, M. J., James, J., Murray, K., Appleyard, V., Prescott, A. R., Drbal, A. A., Nicolaou, A., Cunningham, J., Haydock, S., Ganley, I. G., Westwood, N. J., Coates, P. J., Lain, S. & Tauro, S. 1-Jan-2013 In : Scientific Reports. 3, 1275

    Research output: Contribution to journal › Article

  45. The reliability of the Greulich and Pyle Atlas when applied to a modern Scottish population

    Hackman, L. & Black, S. 1-Jan-2013 In : Journal of Forensic Sciences. 58, 1, p. 114-119, 6 p.

    Research output: Contribution to journal › Article

  46. Longitudinal assessment of endothelial function in the microvasculature of mice in-vivo

    Belch, J. J. F., Akbar, N., Alapati, V., Petrie, J., Arthur, S. & Khan, F. Jan-2013 In : Microvascular Research. 85, p. 86-92, 7 p.

    Research output: Contribution to journal › Article

  47. The role of amino acid transporters in nutrition

    Poncet, N. & Taylor, P. M. Jan-2013 In : Current Opinion in Clinical Nutrition and Metabolic Care. 16, 1, p. 57-65, 9 p.

    Research output: Contribution to journal › Article

  48. A sweet TET-a-tete-synergy of TET proteins and O-GlcNAc transferase in transcription

    Mariappa, D., Pathak, S. & van Aalten, D. M. F. 2013 In : EMBO Journal. 32, 5, p. 612-613, 2 p.

    Research output: Contribution to journal › Editorial

  49. A test of the Whitaker scoring system for estimating age from the bones of the foot

    Davies, C., Black, S. M. & Hackman, L. 2013 In : International Journal of Legal Medicine. 127, 2, p. 481-489, 9 p.

    Research output: Contribution to journal › Article

  50. Ca2+ signalling through CatSper and Ca2+ stores regulate different behaviours in human sperm

    Alasmari, W., Costello, S., Correia, J., Oxenham, S. K., Morris, J., Fernandes, L., Ramalho Santos, J., Kirkman-Brown, J., Michelangeli, F., Publicover, S. & Barratt, C. L. R. 2013 In : Journal of Biological Chemistry.

    Research output: Contribution to journal › Article

  51. Chronic exposure of astrocytes to interferon-alpha reveals molecular changes related to Aicardi-Goutieres syndrome

    Cuadrado, E., Jansen, M. H., Anink, J., De Filippis, L., Vescovi, A. L., Watts, C., Aronica, E., Hol, E. M. & Kuijpers, T. W. 2013 In : Brain. 136, 1, p. 245-258, 14 p.

    Research output: Contribution to journal › Article

  52. Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay.

    De Rycker, M., Hallyburton, I., Thomas, J., Campbell, L., Wyllie, S., Joshi, D., Cameron, S., Gilbert, I. H., Wyatt, P. G., Frearson, J. A., Fairlamb, A. H. & Gray, D. W. 2013 In : Antimicrobial Agents and Chemotherapy.

    Research output: Contribution to journal › Article

  53. Detecting and quantifying p53 isoforms at mRNA level in cell lines and tissues

    Khoury, M. P., Marcel, V., Fernandes, K., Diot, A., Lane, D. P. & Bourdon, J-C. 2013 p53 protocols. Deb, S. & Deb, S. P. (eds.). Totowa, N.J.: Humana Press, Vol. 962, p. 1-14 14 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed)

  54. Detecting p53 isoforms at protein level

    Marcel, V., Khoury, M. P., Fernandes, K., Diot, A., Lane, D. P. & Bourdon, J-C. 2013 p53 protocols. Deb, S. & Deb, S. P. (eds.). Totowa, N.J.: Humana Press, Vol. 962, p. 15-29 15 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed)

  55. Development of an enzyme-linked immunosorbent assay for detection of cellular and in vivo LRRK2 S935 phosphorylation

    Delbroek, L., Van Kolen, K., Steegmans, L., da Cunha, R., Mandemakers, W., Daneels, G., De Bock, P-J., Zhang, J., Gevaert, K., De Strooper, B., Alessi, D. R., Verstreken, P. & Moechars, D. W. 2013 In : Journal of Pharmaceutical and Biomedical Analysis. 76, p. 49-58, 10 p.

    Research output: Contribution to journal › Article

  56. Dual regulation of Glycogen Synthase Kinase 3 (GSK3)alpha/beta by Protein Kinase C (PKC)alpha and Akt promotes Thrombin-mediated Integrin alpha(IIb)beta(3) activation and granule secretion in platelets

    Moore, S. F., van den Bosch, M. T. J., Hunter, R. W., Sakamoto, K., Poole, A. W. & Hers, I. 2013 In : Journal of Biological Chemistry. 288, 6, p. 3918-3928, 11 p.

    Research output: Contribution to journal › Article

  57. Electromechanical Behaviour of Nafion-based Soft Actuators

    Naji, L., Chudek, J. A., Abel, E. W. & Baker, R. T. 2013 In : Journal of Physical Chemistry B. 1, 19, p. 2502-2514, 13 p.

    Research output: Contribution to journal › Article

  58. Fungal biotransformation of zinc silicate and sulfide mineral ores.

    Wei, Z., Liang, X., Pendlowski, H., Hillier, S., Suntornvongsagul, K., Sihanonth, P. & Gadd, G. M. 2013 In : Environmental Microbiology. 14 p.

    Research output: Contribution to journal › Article

  59. How does glucophage (metformin) work? Investigation of the cellular action of chemical analogues

    Logie, L., Bacon, S., Middleton, P., Harthill, J., Coats, J., Stewart, D., Sakamoto, K., McDougall, G. & Rena, G. 2013

    Research output: Contribution to conference › Poster

  60. Humeral head arthroplasty and its ability to restore original humeral head geometry

    Harrold, F. & Wigderowitz, C. 2013 In : Journal of shoulder and elbow surgery. 22, 1, p. 115-121, 7 p.

    Research output: Contribution to journal › Article

  61. Identification and Characterization of miRNA Transcriptome in Potato by High-Throughput Sequencing

    Zhang, R., Marshall, D., Bryan, G. J. & Hornyik, C. 2013 In : PLoS ONE. 8, 2, 9 p., ARTN e57233

    Research output: Contribution to journal › Article

  62. Insulin sensitising effects of monounsaturated and polyunsaturated fatty acids in skeletal muscle cells

    Nardi, F., Lipina, C., Magill, D. & Hundal, H. S. 2013

    Research output: Contribution to conference › Poster

  63. Kinase drug discovery: What's next in the field?

    Cohen, P. & Alessi, D. R. 2013 In : ACS Chemical Biology. 8, 1, p. 96-104, 9 p.

    Research output: Contribution to journal › Article

  64. MSK1 and 2 inhibit LPS induced prostaglandin production via an IL-10 feedback loop

    Mackenzie, K. F., Van Den Bosch, M. W. M., Naqvi, S., Elcombe, S. E., McGuire, V. A., Reith, A. D., Blackshear, P. J., Dean, J. L. & Arthur, J. S. C. 2013 In : Molecular and Cellular Biology.

    Research output: Contribution to journal › Article

  65. Neuroprotective effects of digested polyphenols from wild blackberry species

    Tavares, L., Figueira, I., McDougall, G. J., Vieira, H. L. A., Stewart, D., Alves, P. M., Ferreira, R. B. & Santos, C. N. 2013 In : European Journal of Nutrition. 52, 1, p. 225-236, 12 p.

    Research output: Contribution to journal › Article

  66. Phospholipase C-eta 2 is required for retinoic acid-stimulated neurite growth

    Popovics, P., Gray, A., Arastoo, M., Finelli, D. K., Tan, A. J. L. & Stewart, A. J. 2013 In : Journal of Neurochemistry. 124, 5, p. 632-644, 13 p.

    Research output: Contribution to journal › Article

  67. Proteome wide purification and identification of O-GlcNAc-modified proteins using click chemistry and mass spectrometry

    Hahne, H., Sobotzki, N., Nyberg, T., Helm, D., Borodkin, V. S., van Aalten, D. M. F., Agnew, B. & Kuster, B. 2013 In : Journal of Proteome Research. 12, 2, p. 927-936, 10 p.

    Research output: Contribution to journal › Article

  68. Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer

    Alessi, D. R. & 21 others Eser, S., Reiff, N., Messer, M., Seidler, B., Gottschalk, K., Dobler, M., Hieber, M., Arbeiter, A., Klein, S., Kong, B., Michalski, C. W., Schlitter, A. M., Esposito, I., Kind, A. J., Rad, L., Schnieke, A. E., Baccarini, M., Rad, R., Schmid, R. M., Schneider, G. & Saur, D. 2013 In : Cancer Cell. 23, 3, p. 406-420, 15 p.

    Research output: Contribution to journal › Article

  69. Structure of Pseudomonas aeruginosa inosine 5-monophosphate dehydrogenase

    Rao, V. A., Shepherd, S. M., Owen, R. & Hunter, W. N. 2013 In : Acta Crystallographica F-Structural Biology and Crystallization Communications. 69, 3, p. 243-247, 5 p.

    Research output: Contribution to journal › Article

  70. Team-based learning: A practical guide: Guide Supplement 65.1-Viewpoint

    Khogali, S. E. 2013 In : Medical Teacher. 35, 2, p. 163-165, 3 p.

    Research output: Contribution to journal › Article

  71. The amidation step of Diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction network

    Uthman, S., Baer, C., Scheidt, V., Liu, S., Ten Have, S., Giorgini, F., Stark, M. J. R. & Schaffrath, R. 2013 In : PLoS Genetics. 9, 2, e1003334

    Research output: Contribution to journal › Article

  72. The LKB1-AMPK Pathway-Friend or Foe in Cancer?

    Hardie, D. G. 2013 In : Cancer Cell. 23, 2, p. 131-132, 2 p.

    Research output: Contribution to journal › Editorial

  73. The plasticity of a structural motif in RNA: Structural polymorphism of a kink turn as a function of its environment

    Daldrop, P. & Lilley, D. M. J. 2013 In : RNA: a Publication of the RNA Society. 19, 3, p. 357-364, 8 p.

    Research output: Contribution to journal › Article

  74. The specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability

    Elliott, J. L., Der Perng, M., Prescott, A. R., Jansen, K. A., Koenderink, G. H. & Quinlan, R. A. 2013 In : Philosophical Transactions of the Royal Society B - Biological Sciences. 368, 1617, p. 1-15, 15 p.

    Research output: Contribution to journal › Article

  75. The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow

    Lek, H. S., Morrison, V. L., Conneely, M., Campbell, P. A., McGloin, D., Kliche, S., Watts, C., Prescott, A. & Fagerholm, S. C. 2013 In : Journal of Biological Chemistry.

    Research output: Contribution to journal › Article

  76. PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8 T cells

    Finlay, D. K., Rosenzweig, E., Sinclair, L. V., Feijoo-Carnero, C., Hukelmann, J. L., Rolf, J., Panteleyev, A. A., Okkenhaug, K. & Cantrell, D. A. 17-Dec-2012 In : Journal of Experimental Medicine. 209, 13, p. 2441-2453, 13 p.

    Research output: Contribution to journal › Article

  77. Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P-3-dependent mechanisms leading to resistance to PDK1 inhibitors

    Najafov, A., Shpiro, N. & Alessi, D. R. Dec-2012 In : Biochemical Journal. 448, 2, p. 285-295, 11 p.

    Research output: Contribution to journal › Article

  78. An hnRNP-like RNA-binding protein affects alternative splicing by in vivo interaction with transcripts in Arabidopsis thaliana

    Streitner, C., Köster, T., Simpson, C. G., Shaw, P., Danisman, S., Brown, J. W. S. & Staiger, D. Dec-2012 In : Nucleic Acids Research. 40, 22, p. 11240-11255, 16 p.

    Research output: Contribution to journal › Article

  79. Crop genome plasticity and its Relevance to food and feed safety of genetically engineered breeding stacks

    Weber, N., Halpin, C., Curtis Hannah, L., Jez, J. M., Kough, J. & Parrott, W. Dec-2012 In : Plant Physiology. 160, 4, p. 1842-1853, 12 p.

    Research output: Contribution to journal › Article

  80. Estimating root-soil contact from 3D X-ray microtomographs

    Schmidt, S., Bengough, A. G., Gregory, P. J., Grinev, D. V. & Otten, W. Dec-2012 In : European Journal of Soil Science. 63, 6, p. 776-786, 11 p.

    Research output: Contribution to journal › Article

  81. Relocalization of late blight resistance protein r3a to endosomal compartments is associated with effector recognition and required for the immune response.

    Engelhardt, S., Boevink, P. C., Armstrong, M. R., Ramos, M. B., Hein, I. & Birch, P. R. J. Dec-2012 In : Plant Cell. 24, 12, p. 5142-5158, 16 p.

    Research output: Contribution to journal › Article

  82. Selective kinase inhibitors as tools for neuroscience research

    Martin, K. J. & Arthur, J. S. C. Dec-2012 In : Neuropharmacology. 63, 7, p. 1227-1237, 11 p.

    Research output: Contribution to journal › Article

  83. Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases

    McIver, E. G., Bryans, J., Birchall, K., Chugh, J., Drake, T., Lewis, S. J., Osborne, J., Smiljanic-Hurley, E., Tsang, W., Kamal, A., Levy, A., Newman, M., Taylor, D., Arthur, J. S. C., Clark, K. & Cohen, P. Dec-2012 In : Bioorganic & Medicinal Chemistry Letters. 22, 23, p. 7169-7173, 5 p.

    Research output: Contribution to journal › Article

  84. A physical, genetic and functional sequence assembly of the barley genome

    Mayer, K. F. X., Waugh, R., Brown, J. W. S., Schulman, A., Langridge, P., Platzer, M., Fincher, G. B., Muehlbauer, G. J., Sato, K., Close, T. J., Wise, R. P., Stein, N. & International Barley Genome Sequencing Consortium 29-Nov-2012 In : Nature. 491, 7426, p. 711-6, 6 p.

    Research output: Contribution to journal › Article

  85. A static-cidal assay for Trypanosoma brucei to aid hit prioritisation for progression into drug discovery programmes

    De Rycker, M., O'Neill, S., Joshi, D., Campbell, L., Gray, D. W. & Fairlamb, A. H. 29-Nov-2012 In : PLoS Neglected Tropical Diseases. 6, 11, p. e1932

    Research output: Contribution to journal › Article

  86. Structural plasticity of histones H3–H4 facilitates their allosteric exchange between RbAp48 and ASF1

    Zhang, W., Yyl, M., Ward, R., Sobott, F., Maman, J., Murthy, A., Watson, A., Fedorov, O., Bowman, A., Owen-Hughes, T., El Mkami, H., Murzina, N., Norman, D. G. & Laue, E. 25-Nov-2012 In : Nature Structural & Molecular Biology. 20, 1, p. 29-35

    Research output: Contribution to journal › Article

  87. Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase

    Shehata, S. N., Hunter, R. W., Ohta, E., Peggie, M. W., Lou, H. J., Sicheri, F., Zegiraj, E., Turk, B. E. & Sakamoto, K. Nov-2012 In : Cellular Signalling. 24, 11, p. 2085-2094, 10 p.

    Research output: Contribution to journal › Article

  88. Chemical Proteomic Analysis Reveals the Drugability of the Kinome of Trypanosoma brucei

    Urbaniak, M. D., Mathieson, T., Bantscheff, M., Eberhard, D., Grimaldi, R., Miranda-Saavedra, D., Wyatt, P., Ferguson, M. A. J., Frearson, J. & Drewes, G. Nov-2012 In : ACS Chemical Biology. 7, 11, p. 1858-1865, 8 p.

    Research output: Contribution to journal › Article

  89. New secreted toxins and immunity proteins encoded within the type VI secretion system gene cluster of Serratia marcescens

    English, G., Trunk, K., Rao, V. A., Srikannathasan, V., Hunter, W. N. & Coulthurst, S. J. Nov-2012 In : Molecular Microbiology. 86, 4, p. 921-936, 16 p.

    Research output: Contribution to journal › Article

  90. Ultramorphology of the ovipositor of Venturia canescens (Gravenhorst) and possible mechanisms for oviposition

    Shah, Z. A., Blackwell, A. & Hubbard, S. F. Nov-2012 In : International Journal of Agriculture and Biology. 14, 6, p. 908-914, 7 p.

    Research output: Contribution to journal › Article

  91. Chemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosome

    Jones, D. C., Alphey, M. S., Wyllie, S. & Fairlamb, A. H. Oct-2012 In : Molecular Microbiology. 86, 1, p. 51-64, 14 p.

    Research output: Contribution to journal › Article

  92. Dormant Origins, the Licensing Checkpoint, and the Response to Replicative Stresses

    McIntosh, D. & Blow, J. J. Oct-2012 In : Cold spring harbor perspectives in biology. 4, 10, 10 p., 012955

    Research output: Contribution to journal › Article

  93. Spatiotemporal asymmetry of the meiotic program underlies the predominantly distal distribution of meiotic crossovers in barley

    Higgins, J. D., Perry, R. M., Barakate, A., Ramsay, L., Waugh, R., Halpin, C., Armstrong, S. J. & Franklin, F. C. H. Oct-2012 In : Plant Cell. 24, 10, p. 4096-4109, 14 p.

    Research output: Contribution to journal › Article

  94. Testing the distinctness of shoot ionomes of angiosperm families using the Rothamsted Park Grass Continuous Hay Experiment

    White, P. J., Broadley, M. R., Thompson, J. A., McNicol, J. W., Crawley, M. J., Poulton, P. R. & Johnston, A. E. Oct-2012 In : New Phytologist. 196, 1, p. 101-109, 9 p.

    Research output: Contribution to journal › Article

  95. Thermoplasticity in the plant circadian clock: how plants tell the time-perature

    James, A. B., Hasan-Syed, N., Brown, J. W. S. & Nimmo, H. G. Oct-2012 In : Plant Signaling and Behavior. 7, 10, p. 1219-23, 5 p.

    Research output: Contribution to journal › Article

  96. Family with Sequence Similarity 60A (FAM60A) Protein Is a Cell Cycle-fluctuating Regulator of the SIN3-HDAC1 Histone Deacetylase Complex

    Munoz, I. M., Macartney, T., Sanchez-Pulido, L., Ponting, C. P., Rocha, S. & Rouse, J. 21-Sep-2012 In : Journal of Biological Chemistry. 287, 39, p. 32346-53, 8 p.

    Research output: Contribution to journal › Article

  97. New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes

    Sandholm, N. , Salem, R. M. , McKnight, A. J. , Brennan, E. P. , Forsblom, C. , Isakova, T. , McKay, G. J. , Williams, W. W. , Sadlier, D. M. , Makinen, V-P. , Swan, E. J. , Palmer, C. , Boright, A. P. , Ahlqvist, E. , Deshmukh, H. A. , Keller, B. J. , Huang, H. , Ahola, A. J. , Fagerholm, E. , Gordin, D. & 73 others Harjutsalo, V., He, B., Heikkila, O., Hietala, K., Kyto, J., Lahermo, P., Lehto, M., Lithovius, R., Osterholm, A-M., Parkkonen, M., Pitkaniemi, J., Rosengard-Barlund, M., Saraheimo, M., Sarti, C., Soderlund, J., Soro-Paavonen, A., Syreeni, A., Thorn, L. M., Tikkanen, H., Tolonen, N., Tryggvason, K., Tuomilehto, J., Waden, J., Gill, G. V., Prior, S., Guiducci, C., Mirel, D. B., Taylor, A., Hosseini, S. M., Parving, H-H., Rossing, P., Tarnow, L., Ladenvall, C., Alhenc-Gelas, F., Lefebvre, P., Rigalleau, V., Roussel, R., Tregouet, D-A., Maestroni, A., Maestroni, S., Falhammar, H., Gu, T., Mollsten, A., Cimponeriu, D., Ioana, M., Mota, M., Mota, E., Serafinceanu, C., Stavarachi, M., Hanson, R. L., Nelson, R. G., Kretzler, M., Colhoun, H. M., Panduru, N. M., Gu, H. F., Brismar, K., Zerbini, G., Hadjadj, S., Marre, M., Groop, L., Lajer, M., Bull, S. B., Waggott, D., Paterson, A. D., Savage, D. A., Bain, S. C., Martin, F., Hirschhorn, J. N., Godson, C., Florez, J. C., Groop, P-H., Maxwell, A. P. & DCCT-EDIC Res Grp 20-Sep-2012 In : PLoS Genetics. 8, 9, 13 p., e1002921

    Research output: Contribution to journal › Article

  98. Insulin resistance in the brain: An old-age or new-age problem?

    Williamson, R., McNeilly, A. & Sutherland, C. 15-Sep-2012 In : Biochemical Pharmacology. 84, 6, p. 737-45, 9 p.

    Research output: Contribution to journal › Article

  99. Sialoadhesin Promotes Rapid Proinflammatory and Type I IFN Responses to a Sialylated Pathogen, Campylobacter jejuni

    Klaas, M., Oetke, C., Lewis, L. E., Erwig, L. P., Heikema, A. P., Easton, A., Willison, H. J. & Crocker, P. R. 1-Sep-2012 In : Journal of Immunology. 189, 5, p. 2414-22, 9 p.

    Research output: Contribution to journal › Article

  100. A systems biology view of responses to lignin biosynthesis perturbations in Arabidopsis

    Vanholme, R., Storme, V., Vanholme, B., Sundin, L., Christensen, J. H., Goeminne, G., Halpin, C., Rohde, A., Morreel, K. & Boerjan, W. Sep-2012 In : Plant Cell. 24, 9, p. 3506-3529, 24 p.

    Research output: Contribution to journal › Article

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