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  1. AMPK: positive and negative regulation, and its role in whole-body energy homeostasis

    Hardie, D. G. Apr 2015 In : Current Opinion in Cell Biology. 33, April, p. 1-7 7 p.

    Research output: Contribution to journalArticle

  2. Evaluation of in-situ magnetic signals from iron oxide nanoparticle-labeled PC12 cells by atomic force microscopy

    Wang, L., Min, Y., Wang, Z., Riggio, C., Calatayud, M. P., Pinkernelle, J., Raffa, V., Goya, G. F. ., Keilhoff, G. & Cuschieri, A. Mar 2015 In : Journal of Biomedical Nanotechnology. 11, 3, p. 457-468 12 p.

    Research output: Contribution to journalArticle

  3. Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes

    Spinelli, L., Black, F. M., Berg, J. N., Eickholt, B. J. & Leslie, N. R. 19 Dec 2014 In : Journal of Medical Genetics.

    Research output: Contribution to journalArticle

  4. Managing patients on bisphosphonates: the practice of primary care dentists before and after the publication of national guidance

    Bonetti, D. L., Clarkson, J. E., Elouafkaoui, P., Stirling, D. A., Young, L. & Templeton, A. R. 19 Dec 2014 In : British Dental Journal. 217, 12, p. E25

    Research output: Contribution to journalArticle

  5. The Dictyostelium prestalk inducer Differentiation Inducing Factor-1 (DIF-1) triggers unexpectedly complex global phosphorylation changes

    Sugden, C., Urbaniak, M. D., Araki, T. & Williams, J. G. 17 Dec 2014 In : Molecular Biology of the Cell.

    Research output: Contribution to journalArticle

  6. A cyanobacterial light activated adenylyl cyclase partially restores development of a Dictyostelium discoideum, adenylyl cyclase a null mutant

    Chen, Z., Raffelberg, S., Losi, A., Schaap, P. & Gärtner, W. 10 Dec 2014 In : Journal of Biotechnology. 191, p. 246-249 4 p.

    Research output: Contribution to journalArticle

  7. GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes

    Freeman, A. D. J., Liu, Y., Déclais, A-C., Gartner, A. & Lilley, D. M. J. Dec 2014 In : Journal of Molecular Biology. 426, 24, p. 3946-3959 14 p.

    Research output: Contribution to journalArticle

  8. A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

    Alessi, D. R. & 27 others Schönhuber, N., Seidler, B., Schuck, K., Veltkamp, C., Schachtler, C., Zukowska, M., Eser, S., Feyerabend, T. B., Paul, M. C., Eser, P., Klein, S., Lowy, A. M., Banerjee, R., Yang, F., Lee, C-L., Moding, E. J., Kirsch, D. G., Scheideler, A., Varela, I., Bradley, A., Kind, A., Schnieke, A. E., Rodewald, H-R., Rad, R., Schmid, R. M., Schneider, G. & Saur, D. Nov 2014 In : Nature Medicine. 20, 11, p. 1340-1347 8 p.

    Research output: Contribution to journalArticle

  9. A novel osteotomy in shoulder joint replacement based on analysis of the cartilage/metaphyseal interface

    Harrold, F., Malhas, A. & Wigderowitz, C. Nov 2014 In : Clinical Biomechanics. 29, 9, p. 1032-1038 7 p.

    Research output: Contribution to journalArticle

  10. Carnosic acid stimulates glucose uptake in skeletal muscle cells via a PME-1/PP2A/PKB signalling axis

    Lipina, C. & Hundal, H. S. Nov 2014 In : Cellular Signalling. 26, 11, p. 2343-2349 6 p.

    Research output: Contribution to journalArticle

  11. Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

    Bago, R., Malik, N., Munson, M. J., Prescott, A. R., Davies, P., Sommer, E., Shpiro, N., Ward, R., Cross, D., Ganley, I. G. & Alessi, D. R. Nov 2014 In : Biochemical Journal. 463, 3, p. 413-427 15 p.

    Research output: Contribution to journalArticle

  12. Laparoscopic nephrectomy for Adult Polycystic Kidney Disease (APKD): safety, feasibility and early outcomes

    Williamson, A., Paterson, S., Erolin, C., Sweeney, C., Townell, N. & Nabi, G. Nov 2014 In : Journal of Endourology. 28, 11, p. 1268-1277 10 p.

    Research output: Contribution to journalArticle

  13. The spatial effect of protein deuteration on nitroxide spin-label relaxation: implications for EPR distance measurement

    El Mkami, H., Ward, R., Bowman, A., Owen-Hughes, T. & Norman, D. G. Nov 2014 In : Journal of Magnetic Resonance . 248, p. 36-41 6 p.

    Research output: Contribution to journalArticle

  14. Detection of the virulent form of AVR3a from Phytophthora infestans following artificial evolution of potato resistance gene R3a

    Chapman, S., Stevens, L. J., Boevink, P. C., Engelhardt, S., Alexander, C. J., Harrower, B., Champouret, N., McGeachy, K., Van Weymers, P. S. M., Chen, X., Birch, P. R. J. & Hein, I. 23 Oct 2014 In : PLoS ONE. 9, 10, 11 p.e110158

    Research output: Contribution to journalArticle

  15. Two Dictyostelium Tyrosine Kinase-Like kinases function in parallel, stress-induced STAT activation pathways

    Araki, T., Vu, L. H., Sasaki, N., Kawata, T., Eichinger, L. & Williams, J. G. 15 Oct 2014 In : Molecular Biology of the Cell. 25, 20, p. 3222-3233 12 p.

    Research output: Contribution to journalArticle

  16. Improved genome editing in human cell lines using the CRISPR method

    Munoz, I. M., Szyniarowski, P., Toth, R., Rouse, J. & Lachaud, C. 10 Oct 2014 In : PLoS ONE. 9, 10, 6 p.e109752

    Research output: Contribution to journalArticle

  17. Membrane lipid peroxidation by the peroxidase-like activity of magnetite nanoparticles

    Wang, L., Min, Y., Xu, D., Yu, F., Zhou, W. & Cuschieri, A. 4 Oct 2014 In : Chemical Communications. 50, 76, p. 11147-11150 4 p.

    Research output: Contribution to journalArticle

  18. A 3D cellular context for the macromolecular world

    Patwardhan, A. , Ashton, A. , Brandt, R. , Butcher, S. , Carzaniga, R. , Chiu, W. , Collinson, L. , Doux, P. , Duke, E. , Ellisman, M. H. , Franken, E. , Grünewald, K. , Heriche, J-K. , Koster, A. , Kühlbrandt, W. , Lagerstedt, I. , Larabell, C. , Lawson, C. L. , Saibil, H. R. , Sanz-García, E. & 4 others Subramaniam, S., Verkade, P., Swedlow, J. R. & Kleywegt, G. J. Oct 2014 In : Nature Structural & Molecular Biology. 21, 10, p. 841-845 5 p.

    Research output: Contribution to journalComment/debate

  19. Beyond nutrition and agriculture policy: collaborating for a food policy

    Stewart, D., Kennedy, A. & Pavel, A. Oct 2014 In : British Journal of Nutrition. 112 , Suppl. 2, p. S65-S74 10 p.

    Research output: Contribution to journalArticle

  20. Elevated O-GlcNAc levels activate epigenetically repressed genes and delay mouse ES cell differentiation without affecting naive to primed cell transition

    Speakman, C. M., Domke, T. C. E., Wongpaiboonwattana, W., Sanders, K., Mudaliar, M., van Aalten, D. M. F., Barton, G. J. & Stavridis, M. P. Oct 2014 In : Stem Cells. 32, 10, p. 2605-2615

    Research output: Contribution to journalArticle

  21. Fungal transformation of metallic lead to pyromorphite in liquid medium

    Rhee, Y. J., Hillier, S., Pendlowski, H. & Gadd, G. M. Oct 2014 In : Chemosphere. 113, p. 17-21 5 p.

    Research output: Contribution to journalArticle

  22. Oat agriculture, cultivation and breeding targets: implications for human nutrition and health

    Stewart, D. & McDougall, G. Oct 2014 In : British Journal of Nutrition. 112 , Suppl. 2, p. S50-S57 8 p.

    Research output: Contribution to journalArticle

  23. Phosphoproteomics combined with quantitative 14-3-3-affinity capture identifies SIRT1 and RAI as novel regulators of cytosolic double-stranded RNA recognition pathway

    Öhman, T., Söderholm, S., Hintsanen, P., Välimäki, E., Lietzén, N., MacKintosh, C., Aittokallio, T., Matikainen, S. & Nyman, T. A. Oct 2014 In : Molecular & Cellular Proteomics. 13, 10, p. 2604-2617 14 p.

    Research output: Contribution to journalArticle

  24. Photosynthetic potential of planets in 3: 2 spin-orbit resonances

    Brown, S. P., Mead, A. J., Forgan, D. H., Raven, J. A. & Cockell, C. S. Oct 2014 In : International Journal of Astrobiology. 13, 4, p. 279-289 11 p.

    Research output: Contribution to journalArticle

  25. Siglec-mediated regulation of immune cell function in disease

    Macauley, M. S., Crocker, P. R. & Paulson, J. C. Oct 2014 In : Nature Reviews Immunology. 14, 10, p. 653-666 14 p.

    Research output: Contribution to journalArticle

  26. Stem cell decisions: A twist of fate or a niche market?

    Januschke, J. & Nathke, I. Oct 2014 In : Seminars in Cell & Developmental Biology. 34, p. 116-123 8 p.

    Research output: Contribution to journalScientific review

  27. Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction

    Roche, S. L., Sherman, D. L., Dissanayake, K., Soucy, G., Desmazieres, A., Lamont, D. J., Peles, E., Julien, J-P., Wishart, T. M., Ribchester, R. R., Brophy, P. J. & Gillingwater, T. H. 17 Sep 2014 In : Journal of Neuroscience. 34, 38, p. 12904-12918 15 p.

    Research output: Contribution to journalArticle

  28. Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks

    Albergante, L., Blow, J. J. & Newman, T. J. 2 Sep 2014 In : eLife. 3, 28 p.e02863

    Research output: Contribution to journalArticle

  29. In silico identification and characterization of conserved plant microRNAs in barley

    Wu, X., Hornyik, C., Bayer, M., Marshall, D., Waugh, R. & Zhang, R. Sep 2014 In : Central European Journal of Biology. 9, 9, p. 841-852 12 p.

    Research output: Contribution to journalArticle

  30. Barley has two peroxisomal ABC transporters with multiple functions in β-oxidation

    Mendiondo, G. M., Medhurst, A., van Roermund, C. W., Zhang, X., Devonshire, J., Scholefield, D., Fernández, . J., Axcell, B., Ramsay, L., Waterham, H. R., Waugh, R., Theodoulou, F. L. & Holdsworth, M. J. Sep 2014 In : Journal of Experimental Botany. 65, 17, p. 4833-4847 15 p.

    Research output: Contribution to journalArticle

  31. Crystal structure and mechanistic investigation of the twister ribozyme

    Liu, Y., Wilson, T. J., McPhee, S. A. & Lilley, D. M. J. Sep 2014 In : Nature Chemical Biology. 10, 9, p. 739-744 6 p.

    Research output: Contribution to journalArticle

  32. Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains

    Kneuper, H., Cao, Z. P., Twomey, K. B., Zoltner, M., Jäger, F., Cargill, J. S., Chalmers, J., van der Kooi-Pol, M. M., van Dijl, J. M., Ryan, R. P., Hunter, W. N. & Palmer, T. Sep 2014 In : Molecular Microbiology. 93, 5, p. 928-943 15 p.

    Research output: Contribution to journalArticle

  33. Sequence diversity in the large subunit of RNA polymerase I contributes to Mefenoxam insensitivity in Phytophthora infestans

    Randall, E., Young, V., Sierotzki, H., Scalliet, G., Birch, P. R. J., Cooke, D. E. L., Csukai, M. & Whisson, S. C. Sep 2014 In : Molecular Plant Pathology. 15, 7, p. 664-676 13 p.

    Research output: Contribution to journalArticle

  34. The low recombining pericentromeric region of barley restricts gene diversity and evolution but not gene expression

    Baker, K., Bayer, M., Cook, N., Dreißig, S., Dhillon, T., Russell, J., Hedley, P. E., Morris, J., Ramsay, L., Colas, I., Waugh, R., Steffenson, B., Milne, I., Stephen, G., Marshall, D. & Flavell, A. J. Sep 2014 In : Plant Journal. 79, 6, p. 981-992 12 p.

    Research output: Contribution to journalArticle

  35. Screening-based discovery of Aspergillus fumigatus plant-type chitinase inhibitors

    Lockhart, D. E. A., Schuettelkopf, A., Blair, D. E. & van Aalten, D. M. F. 25 Aug 2014 In : FEBS Letters. 588, 17, p. 3282-3290 9 p.

    Research output: Contribution to journalArticle

  36. Direct contacts with colon cancer cells regulate the differentiation of bone marrow mesenchymal stem cells into tumor associated fibroblasts

    Peng, Y., Li, Z., Yang, P., Newton, I. P., Ren, H., Zhang, L., Wu, H. & Li, Z. 15 Aug 2014 In : Biochemical and Biophysical Research Communications. 451, 1, p. 68-73 6 p.

    Research output: Contribution to journalArticle

  37. Structure-based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1

    Khalaf, A. I., Huggan, J. K., Suckling, C. J., Gibson, C. L., Stewart, K., Giordani, F., Barrett, M. P., Wong, P. E., Barrack, K. L. & Hunter, W. N. 14 Aug 2014 In : Journal of Medicinal Chemistry. 57, 15, p. 6479-6494 16 p.

    Research output: Contribution to journalArticle

  38. Further occurrences of Dohrniphora cornuta (Bigot) (Diptera, Phoridae) in forensic cases indicate likely importance of this species in future cases

    Disney, R. H. L., Garcia-Rojo, A., Lindström, A. & Manlove, J. D. Aug 2014 In : Forensic Science International. 241, p. e20-e22

    Research output: Contribution to journalArticle

  39. Helium: visualization of large scale plant pedigrees

    Shaw, P. D., Graham, M., Kennedy, J., Milne, I. & Marshall, D. F. Aug 2014 In : BMC Bioinformatics. 15, 15 p.259

    Research output: Contribution to journalArticle

  40. Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo

    Olivera-Martinez, I., Schurch, N., Li, R., Song, J., Halley, P. A., Das, R. M., Burt, D. W., Barton, G. J. & Storey, K. G. Aug 2014 In : Development. 141, 16, p. 3266-3276 11 p.

    Research output: Contribution to journalArticle

  41. Safety and feasibility of retrieval of intragastric balloon followed by antiobesity surgery on the same day

    Young, J. A., Alijani, A., Patil, P. V. & Shimi, S. M. Aug 2014 In : Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 24, 4, p. e137-e139 3 p.

    Research output: Contribution to journalArticle

  42. Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung

    McMillan, S. J., Sharma, R. S., Richards, H. E., Hegde, V. & Crocker, P. R. 18 Jul 2014 In : Journal of Biological Chemistry. 289, 29, p. 20370-20376 7 p.

    Research output: Contribution to journalArticle

  43. The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters

    Alessi, D. R., Zhang, J., Khanna, A., Hochdörfer, T., Shang, Y. & Kahle, K. T. 15 Jul 2014 In : Science Signaling. 7, 334, 10 p.re3

    Research output: Contribution to journalArticle

  44. Algae

    Raven, J. A. & Giordano, M. 7 Jul 2014 In : Current Biology. 24, 13, p. R590-R595 6 p.

    Research output: Contribution to journalArticle

  45. Extremely short-duration high-intensity training substantially improves the physical function and self-reported health status of elderly adults

    Adamson, S. B., Lorimer, R., Cobley, J. N. & Babraj, J. Jul 2014 In : Journal of the American Geriatrics Society. 62, 7, p. 1380-1 2 p.

    Research output: Contribution to journalArticle

  46. Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

    Cole, C., Kroboth, K., Schurch, N. J., Sandilands, A., Sherstnev, A., O'Regan, G. M., Watson, R. M., McLean, W. H. I., Barton, G. J., Irvine, A. D. & Brown, S. J. Jul 2014 In : Journal of Allergy and Clinical Immunology. 134, 1, p. 82-91 10 p.

    Research output: Contribution to journalArticle

  47. The contribution of dormant origins to genome stability: from cell biology to human genetics

    Alver, R. C., Chadha, G. S. & Blow, J. J. Jul 2014 In : DNA Repair. 19, p. 182-189 8 p.

    Research output: Contribution to journalArticle

  48. Glycogen Synthase Kinase (GSK) 3β phosphorylates and protects nuclear myosin 1c from proteasome-mediated degradation to activate rDNA transcription in early G1 cells

    Sarshad, A. A., Corcoran, M., Al-Muzzaini, B., Borgonovo-Brandter, L., Von Euler, A., Lamont, D., Visa, N. & Percipalle, P. 5 Jun 2014 In : PLoS Genetics. 10, 6, 17 p.e1004390

    Research output: Contribution to journalArticle

  49. PDK1 controls upstream PI3K expression and PIP3 generation

    Dieterle, A. M., Böhler, P., Keppeler, H., Alers, S., Berleth, N., Drießen, S., Hieke, N., Pietkiewicz, S., Löffler, A. S., Peter, C., Gray, A., Leslie, N. R., Shinohara, H., Kurosaki, T., Engelke, M., Wienands, J., Bonin, M., Wesselborg, S. & Stork, B. 5 Jun 2014 In : Oncogene. 33, 23, p. 3043-3053 11 p.

    Research output: Contribution to journalArticle

  50. A conserved and essential basic region mediates tRNA binding to the Elp1 subunit of the Saccharomyces cerevisiae Elongator complex

    Di Santo, R., Bandau, S. & Stark, M. J. R. Jun 2014 In : Molecular Microbiology. 92, 6, p. 1227-1242 16 p.

    Research output: Contribution to journalArticle

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