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  1. Secreted cyclic di-GMP induces stalk cell differentiation in the eukaryote Dictyostelium discoideum

    Chen, Z. H. & Schaap, P. Jan 2016 In : Journal of Bacteriology. 198, 1, p. 27-31 5 p.

    Research output: Contribution to journalArticle

  2. Evidence for a functional O-linked N-acetylglucosamine (O-GlcNAc) system in the thermophilic bacterium Thermobaculum terrenum

    Ostrowski, A., Gundogdu, M., Ferenbach, A. T., Lebedev, A. A. & Van Aalten, D. M. F. 18 Dec 2015 In : Journal of Biological Chemistry. 290, 51, p. 30291-30305 15 p.

    Research output: Contribution to journalArticle

  3. Genomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African Trypanosome

    Jones, D. C., Foth, B. J., Urbaniak, M. D., Patterson, S., Ong, H. B., Berriman, M. & Fairlamb, A. H. 18 Dec 2015 In : PLoS Neglected Tropical Diseases. 9, 12, e0004299

    Research output: Contribution to journalArticle

  4. Subverting toll-like receptor signaling by bacterial pathogens

    McGuire, V. A. & Arthur, J. S. C. 1 Dec 2015 In : Frontiers in Immunology. 6, DEC, 8 p., 607

    Research output: Contribution to journalArticle

  5. Integration of an [FeFe]-hydrogenase into the anaerobic metabolism of Escherichia coli

    Kelly, C. L., Pinske, C., Murphy, B. J., Parkin, A., Armstrong, F., Palmer, T. & Sargent, F. Dec 2015 In : Biotechnology Reports. 8, p. 94-104 11 p.

    Research output: Contribution to journalArticle

  6. The Concise Guide to PHARMACOLOGY 2015/16: Overview

    Alexander, S. P. H., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C., Buneman, O. P., Catterall, W. A., Cidlowski, J. A., Davenport, A. P., Fabbro, D., Fan, G., McGrath, J. C., Spedding, M. & Davies, J. A. Dec 2015 In : British Journal of Pharmacology. 172, 24, p. 5729-5743 15 p.

    Research output: Contribution to journalArticle

  7. Transformation of vanadinite (Pb5 (VO4 )3 Cl) by fungi

    Ceci, A., Rhee, Y. J., Kierans, M., Hillier, S., Pendlowski, H., Gray, N., Persiani, A. M. & Gadd, G. M. Jun 2015 In : Environmental Microbiology. 17, 6, p. 2018-2034 17 p.

    Research output: Contribution to journalArticle

  8. Uranium phosphate biomineralization by fungi

    Liang, X., Hillier, S., Pendlowski, H., Gray, N., Ceci, A. & Gadd, G. M. Jun 2015 In : Environmental Microbiology. 17, 6, p. 2064-2075 12 p.

    Research output: Contribution to journalArticle

  9. AMPK: positive and negative regulation, and its role in whole-body energy homeostasis

    Hardie, D. G. Apr 2015 In : Current Opinion in Cell Biology. 33, April, p. 1-7 7 p.

    Research output: Contribution to journalArticle

  10. Evaluation of in-situ magnetic signals from iron oxide nanoparticle-labeled PC12 cells by atomic force microscopy

    Wang, L., Min, Y., Wang, Z., Riggio, C., Calatayud, M. P., Pinkernelle, J., Raffa, V., Goya, G. F. ., Keilhoff, G. & Cuschieri, A. Mar 2015 In : Journal of Biomedical Nanotechnology. 11, 3, p. 457-468 12 p.

    Research output: Contribution to journalArticle

  11. The Dictyostelium prestalk inducer differentiation inducing factor-1 (DIF-1) triggers unexpectedly complex global phosphorylation changes

    Sugden, C., Urbaniak, M. D., Araki, T. & Williams, J. G. 15 Feb 2015 In : Molecular Biology of the Cell. 26, 4, p. 805-820 16 p.

    Research output: Contribution to journalArticle

  12. Enhanced biofuel production using optimality, pathway modification and waste minimization

    Raven, J. A. & Ralph, P. J. Feb 2015 In : Journal of Applied Phycology. 27, 1, p. 1-31 31 p.

    Research output: Contribution to journalArticle

  13. Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes

    Spinelli, L., Black, F. M., Berg, J. N., Eickholt, B. J. & Leslie, N. R. Feb 2015 In : Journal of Medical Genetics. 52, 2, p. 128-134 7 p.

    Research output: Contribution to journalArticle

  14. Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation

    Pirkmajer, S., Kulkarni, S. S., Tom, R. Z., Ross, F. A., Hawley, S. A., Hardie, D. G., Zierath, J. R. & Chibalin, A. V. Feb 2015 In : Diabetes. 64, 2, p. 360-369 10 p.

    Research output: Contribution to journalArticle

  15. TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei

    Fairlamb, A. H. , Ferguson, M. A. J. & 39 others Shameer, S., Logan-Klumpler, F. J., Vinson, F., Cottret, L., Merlet, B., Achcar, F., Boshart, M., Berriman, M., Breitling, R., Bringaud, F., Bütikofer, P., Cattanach, A. M., Bannerman-Chukualim, B., Creek, D. J., Crouch, K., de Koning, H. P., Denise, H., Ebikeme, C., Ginger, M. L., Hertz-Fowler, C., Kerkhoven, E. J., Mäser, P., Michels, P. A. M., Nayak, A., Nes, D. W., Nolan, D. P., Olsen, C., Silva-Franco, F., Smith, T. K., Taylor, M. C., Tielens, A. G. M., Urbaniak, M. D., van Hellemond, J. J., Vincent, I. M., Wilkinson, S. R., Wyllie, S., Opperdoes, F. R., Barrett, M. P. & Jourdan, F. 28 Jan 2015 In : Nucleic Acids Research. 43, D1, p. D637-D644 8 p.

    Research output: Contribution to journalArticle

  16. Managing patients on bisphosphonates: the practice of primary care dentists before and after the publication of national guidance

    Bonetti, D. L., Clarkson, J. E., Elouafkaoui, P., Stirling, D. A., Young, L. & Templeton, A. R. 19 Dec 2014 In : British Dental Journal. 217, p. E25 7 p.

    Research output: Contribution to journalArticle

  17. O-GlcNAcase: promiscuous hexosaminidase or key regulator of O-GlcNAc signalling?

    Alonso , J., Schimpl, M. & van Aalten, D. M. F. 12 Dec 2014 In : Journal of Biological Chemistry. 289, 50, p. 34433-34439 7 p.

    Research output: Contribution to journalArticle

  18. A cyanobacterial light activated adenylyl cyclase partially restores development of a Dictyostelium discoideum, adenylyl cyclase a null mutant

    Chen, Z., Raffelberg, S., Losi, A., Schaap, P. & Gärtner, W. 10 Dec 2014 In : Journal of Biotechnology. 191, p. 246-249 4 p.

    Research output: Contribution to journalArticle

  19. GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes

    Freeman, A. D. J., Liu, Y., Déclais, A-C., Gartner, A. & Lilley, D. M. J. Dec 2014 In : Journal of Molecular Biology. 426, 24, p. 3946-3959 14 p.

    Research output: Contribution to journalArticle

  20. A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

    Alessi, D. R. & 27 others Schönhuber, N., Seidler, B., Schuck, K., Veltkamp, C., Schachtler, C., Zukowska, M., Eser, S., Feyerabend, T. B., Paul, M. C., Eser, P., Klein, S., Lowy, A. M., Banerjee, R., Yang, F., Lee, C-L., Moding, E. J., Kirsch, D. G., Scheideler, A., Varela, I., Bradley, A., Kind, A., Schnieke, A. E., Rodewald, H-R., Rad, R., Schmid, R. M., Schneider, G. & Saur, D. Nov 2014 In : Nature Medicine. 20, 11, p. 1340-1347 8 p.

    Research output: Contribution to journalArticle

  21. A novel osteotomy in shoulder joint replacement based on analysis of the cartilage/metaphyseal interface

    Harrold, F., Malhas, A. & Wigderowitz, C. Nov 2014 In : Clinical Biomechanics. 29, 9, p. 1032-1038 7 p.

    Research output: Contribution to journalArticle

  22. Carnosic acid stimulates glucose uptake in skeletal muscle cells via a PME-1/PP2A/PKB signalling axis

    Lipina, C. & Hundal, H. S. Nov 2014 In : Cellular Signalling. 26, 11, p. 2343-2349 6 p.

    Research output: Contribution to journalArticle

  23. Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

    Bago, R., Malik, N., Munson, M. J., Prescott, A. R., Davies, P., Sommer, E., Shpiro, N., Ward, R., Cross, D., Ganley, I. G. & Alessi, D. R. Nov 2014 In : Biochemical Journal. 463, 3, p. 413-427 15 p.

    Research output: Contribution to journalArticle

  24. Laparoscopic nephrectomy for Adult Polycystic Kidney Disease (APKD): safety, feasibility and early outcomes

    Williamson, A., Paterson, S., Erolin, C., Sweeney, C., Townell, N. & Nabi, G. Nov 2014 In : Journal of Endourology. 28, 11, p. 1268-1277 10 p.

    Research output: Contribution to journalArticle

  25. The spatial effect of protein deuteration on nitroxide spin-label relaxation: implications for EPR distance measurement

    El Mkami, H., Ward, R., Bowman, A., Owen-Hughes, T. & Norman, D. G. Nov 2014 In : Journal of Magnetic Resonance . 248, p. 36-41 6 p.

    Research output: Contribution to journalArticle

  26. Detection of the virulent form of AVR3a from Phytophthora infestans following artificial evolution of potato resistance gene R3a

    Chapman, S., Stevens, L. J., Boevink, P. C., Engelhardt, S., Alexander, C. J., Harrower, B., Champouret, N., McGeachy, K., Van Weymers, P. S. M., Chen, X., Birch, P. R. J. & Hein, I. 23 Oct 2014 In : PLoS ONE. 9, 10, 11 p., e110158

    Research output: Contribution to journalArticle

  27. Two Dictyostelium Tyrosine Kinase-Like kinases function in parallel, stress-induced STAT activation pathways

    Araki, T., Vu, L. H., Sasaki, N., Kawata, T., Eichinger, L. & Williams, J. G. 15 Oct 2014 In : Molecular Biology of the Cell. 25, 20, p. 3222-3233 12 p.

    Research output: Contribution to journalArticle

  28. Improved genome editing in human cell lines using the CRISPR method

    Munoz, I. M., Szyniarowski, P., Toth, R., Rouse, J. & Lachaud, C. 10 Oct 2014 In : PLoS ONE. 9, 10, 6 p., e109752

    Research output: Contribution to journalArticle

  29. Membrane lipid peroxidation by the peroxidase-like activity of magnetite nanoparticles

    Wang, L., Min, Y., Xu, D., Yu, F., Zhou, W. & Cuschieri, A. 4 Oct 2014 In : Chemical Communications. 50, 76, p. 11147-11150 4 p.

    Research output: Contribution to journalArticle

  30. A 3D cellular context for the macromolecular world

    Patwardhan, A. , Ashton, A. , Brandt, R. , Butcher, S. , Carzaniga, R. , Chiu, W. , Collinson, L. , Doux, P. , Duke, E. , Ellisman, M. H. , Franken, E. , Grünewald, K. , Heriche, J-K. , Koster, A. , Kühlbrandt, W. , Lagerstedt, I. , Larabell, C. , Lawson, C. L. , Saibil, H. R. , Sanz-García, E. & 4 others Subramaniam, S., Verkade, P., Swedlow, J. R. & Kleywegt, G. J. Oct 2014 In : Nature Structural & Molecular Biology. 21, 10, p. 841-845 5 p.

    Research output: Contribution to journalComment/debate

  31. Beyond nutrition and agriculture policy: collaborating for a food policy

    Stewart, D., Kennedy, A. & Pavel, A. Oct 2014 In : British Journal of Nutrition. 112 , Suppl. 2, p. S65-S74 10 p.

    Research output: Contribution to journalArticle

  32. Elevated O-GlcNAc levels activate epigenetically repressed genes and delay mouse ES cell differentiation without affecting naive to primed cell transition

    Speakman, C. M., Domke, T. C. E., Wongpaiboonwattana, W., Sanders, K., Mudaliar, M., van Aalten, D. M. F., Barton, G. J. & Stavridis, M. P. Oct 2014 In : Stem Cells. 32, 10, p. 2605-2615

    Research output: Contribution to journalArticle

  33. Fungal transformation of metallic lead to pyromorphite in liquid medium

    Rhee, Y. J., Hillier, S., Pendlowski, H. & Gadd, G. M. Oct 2014 In : Chemosphere. 113, p. 17-21 5 p.

    Research output: Contribution to journalArticle

  34. Oat agriculture, cultivation and breeding targets: implications for human nutrition and health

    Stewart, D. & McDougall, G. Oct 2014 In : British Journal of Nutrition. 112 , Suppl. 2, p. S50-S57 8 p.

    Research output: Contribution to journalArticle

  35. Phosphoproteomics combined with quantitative 14-3-3-affinity capture identifies SIRT1 and RAI as novel regulators of cytosolic double-stranded RNA recognition pathway

    Öhman, T., Söderholm, S., Hintsanen, P., Välimäki, E., Lietzén, N., MacKintosh, C., Aittokallio, T., Matikainen, S. & Nyman, T. A. Oct 2014 In : Molecular & Cellular Proteomics. 13, 10, p. 2604-2617 14 p.

    Research output: Contribution to journalArticle

  36. Photosynthetic potential of planets in 3 : 2 spin-orbit resonances

    Brown, S. P., Mead, A. J., Forgan, D. H., Raven, J. A. & Cockell, C. S. Oct 2014 In : International Journal of Astrobiology. 13, 4, p. 279-289 11 p.

    Research output: Contribution to journalArticle

  37. Siglec-mediated regulation of immune cell function in disease

    Macauley, M. S., Crocker, P. R. & Paulson, J. C. Oct 2014 In : Nature Reviews Immunology. 14, 10, p. 653-666 14 p.

    Research output: Contribution to journalArticle

  38. Stem cell decisions: A twist of fate or a niche market?

    Januschke, J. & Nathke, I. Oct 2014 In : Seminars in Cell & Developmental Biology. 34, p. 116-123 8 p.

    Research output: Contribution to journalScientific review

  39. Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction

    Roche, S. L., Sherman, D. L., Dissanayake, K., Soucy, G., Desmazieres, A., Lamont, D. J., Peles, E., Julien, J-P., Wishart, T. M., Ribchester, R. R., Brophy, P. J. & Gillingwater, T. H. 17 Sep 2014 In : Journal of Neuroscience. 34, 38, p. 12904-12918 15 p.

    Research output: Contribution to journalArticle

  40. Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks

    Albergante, L., Blow, J. J. & Newman, T. J. 2 Sep 2014 In : eLife. 3, 28 p., e02863

    Research output: Contribution to journalArticle

  41. In silico identification and characterization of conserved plant microRNAs in barley

    Wu, X., Hornyik, C., Bayer, M., Marshall, D., Waugh, R. & Zhang, R. Sep 2014 In : Central European Journal of Biology. 9, 9, p. 841-852 12 p.

    Research output: Contribution to journalArticle

  42. Barley has two peroxisomal ABC transporters with multiple functions in β-oxidation

    Mendiondo, G. M., Medhurst, A., van Roermund, C. W., Zhang, X., Devonshire, J., Scholefield, D., Fernández, . J., Axcell, B., Ramsay, L., Waterham, H. R., Waugh, R., Theodoulou, F. L. & Holdsworth, M. J. Sep 2014 In : Journal of Experimental Botany. 65, 17, p. 4833-4847 15 p.

    Research output: Contribution to journalArticle

  43. Crystal structure and mechanistic investigation of the twister ribozyme

    Liu, Y., Wilson, T. J., McPhee, S. A. & Lilley, D. M. J. Sep 2014 In : Nature Chemical Biology. 10, 9, p. 739-744 6 p.

    Research output: Contribution to journalArticle

  44. Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains

    Kneuper, H., Cao, Z. P., Twomey, K. B., Zoltner, M., Jäger, F., Cargill, J. S., Chalmers, J., van der Kooi-Pol, M. M., van Dijl, J. M., Ryan, R. P., Hunter, W. N. & Palmer, T. Sep 2014 In : Molecular Microbiology. 93, 5, p. 928-943 15 p.

    Research output: Contribution to journalArticle

  45. Sequence diversity in the large subunit of RNA polymerase I contributes to Mefenoxam insensitivity in Phytophthora infestans

    Randall, E., Young, V., Sierotzki, H., Scalliet, G., Birch, P. R. J., Cooke, D. E. L., Csukai, M. & Whisson, S. C. Sep 2014 In : Molecular Plant Pathology. 15, 7, p. 664-676 13 p.

    Research output: Contribution to journalArticle

  46. The low recombining pericentromeric region of barley restricts gene diversity and evolution but not gene expression

    Baker, K., Bayer, M., Cook, N., Dreißig, S., Dhillon, T., Russell, J., Hedley, P. E., Morris, J., Ramsay, L., Colas, I., Waugh, R., Steffenson, B., Milne, I., Stephen, G., Marshall, D. & Flavell, A. J. Sep 2014 In : Plant Journal. 79, 6, p. 981-992 12 p.

    Research output: Contribution to journalArticle

  47. Screening-based discovery of Aspergillus fumigatus plant-type chitinase inhibitors

    Lockhart, D. E. A., Schuettelkopf, A., Blair, D. E. & van Aalten, D. M. F. 25 Aug 2014 In : FEBS Letters. 588, 17, p. 3282-3290 9 p.

    Research output: Contribution to journalArticle

  48. A structural and biochemical model of processive chitin synthesis

    Dorfmueller, H. C., Ferenbach, A. T., Borodkin, V. S. & van Aalten, D. M. F. 15 Aug 2014 In : Journal of Biological Chemistry. 289, p. 23020-23028 9 p.

    Research output: Contribution to journalArticle

  49. Direct contacts with colon cancer cells regulate the differentiation of bone marrow mesenchymal stem cells into tumor associated fibroblasts

    Peng, Y., Li, Z., Yang, P., Newton, I. P., Ren, H., Zhang, L., Wu, H. & Li, Z. 15 Aug 2014 In : Biochemical and Biophysical Research Communications. 451, 1, p. 68-73 6 p.

    Research output: Contribution to journalArticle

  50. Structure-based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1

    Khalaf, A. I., Huggan, J. K., Suckling, C. J., Gibson, C. L., Stewart, K., Giordani, F., Barrett, M. P., Wong, P. E., Barrack, K. L. & Hunter, W. N. 14 Aug 2014 In : Journal of Medicinal Chemistry. 57, 15, p. 6479-6494 16 p.

    Research output: Contribution to journalArticle

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