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  1. AMPK: positive and negative regulation, and its role in whole-body energy homeostasis

    Hardie, D. G. Apr 2015 In : Current Opinion in Cell Biology. 33, April, p. 1-7 7 p.

    Research output: Contribution to journalArticle

  2. Evaluation of in-situ magnetic signals from iron oxide nanoparticle-labeled PC12 cells by atomic force microscopy

    Wang, L., Min, Y., Wang, Z., Riggio, C., Calatayud, M. P., Pinkernelle, J., Raffa, V., Goya, G. F. ., Keilhoff, G. & Cuschieri, A. Mar 2015 In : Journal of Biomedical Nanotechnology. 11, 3, p. 457-468 12 p.

    Research output: Contribution to journalArticle

  3. Carnosic acid stimulates glucose uptake in skeletal muscle cells via a PME-1/PP2A/PKB signalling axis

    Lipina, C. & Hundal, H. S. Nov 2014 In : Cellular Signalling. 26, 11, p. 2343-2349 6 p.

    Research output: Contribution to journalArticle

  4. Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

    Bago, R., Malik, N., Munson, M. J., Prescott, A. R., Davies, P., Sommer, E., Shpiro, N., Ward, R., Cross, D., Ganley, I. G. & Alessi, D. R. Nov 2014 In : Biochemical Journal. 463, 3, p. 413-427 15 p.

    Research output: Contribution to journalArticle

  5. The spatial effect of protein deuteration on nitroxide spin-label relaxation: implications for EPR distance measurement

    El Mkami, H., Ward, R., Bowman, A., Owen-Hughes, T. & Norman, D. G. Nov 2014 In : Journal of Magnetic Resonance . 248, p. 36-41 6 p.

    Research output: Contribution to journalArticle

  6. Detection of the virulent form of AVR3a from Phytophthora infestans following artificial evolution of potato resistance gene R3a

    Chapman, S., Stevens, L. J., Boevink, P. C., Engelhardt, S., Alexander, C. J., Harrower, B., Champouret, N., McGeachy, K., Van Weymers, P. S. M., Chen, X., Birch, P. R. J. & Hein, I. 23 Oct 2014 In : PLoS ONE. 9, 10, 11 p.e110158

    Research output: Contribution to journalArticle

  7. Two Dictyostelium Tyrosine Kinase-Like kinases function in parallel, stress-induced STAT activation pathways

    Araki, T., Vu, L. H., Sasaki, N., Kawata, T., Eichinger, L. & Williams, J. G. 15 Oct 2014 In : Molecular Biology of the Cell. 25, 20, p. 3222-3233 12 p.

    Research output: Contribution to journalArticle

  8. Improved genome editing in human cell lines using the CRISPR method

    Munoz, I. M., Szyniarowski, P., Toth, R., Rouse, J. & Lachaud, C. 10 Oct 2014 In : PLoS ONE. 9, 10, 6 p.e109752

    Research output: Contribution to journalArticle

  9. Membrane lipid peroxidation by the peroxidase-like activity of magnetite nanoparticles

    Wang, L., Min, Y., Xu, D., Yu, F., Zhou, W. & Cuschieri, A. 4 Oct 2014 In : Chemical Communications. 50, 76, p. 11147-11150 4 p.

    Research output: Contribution to journalArticle

  10. A 3D cellular context for the macromolecular world

    Patwardhan, A. , Ashton, A. , Brandt, R. , Butcher, S. , Carzaniga, R. , Chiu, W. , Collinson, L. , Doux, P. , Duke, E. , Ellisman, M. H. , Franken, E. , Grünewald, K. , Heriche, J-K. , Koster, A. , Kühlbrandt, W. , Lagerstedt, I. , Larabell, C. , Lawson, C. L. , Saibil, H. R. , Sanz-García, E. & 4 others Subramaniam, S., Verkade, P., Swedlow, J. R. & Kleywegt, G. J. Oct 2014 In : Nature Structural & Molecular Biology. 21, 10, p. 841-845 5 p.

    Research output: Contribution to journalComment/debate

  11. Beyond nutrition and agriculture policy: collaborating for a food policy

    Stewart, D., Kennedy, A. & Pavel, A. Oct 2014 In : British Journal of Nutrition. 112 , Suppl. 2, p. S65-S74 10 p.

    Research output: Contribution to journalArticle

  12. Elevated O-GlcNAc levels activate epigenetically repressed genes and delay mouse ES cell differentiation without affecting naive to primed cell transition

    Speakman, C. M., Domke, T. C. E., Wongpaiboonwattana, W., Sanders, K., Mudaliar, M., van Aalten, D. M. F., Barton, G. J. & Stavridis, M. P. Oct 2014 In : Stem Cells. 32, 10, p. 2605-2615

    Research output: Contribution to journalArticle

  13. Fungal transformation of metallic lead to pyromorphite in liquid medium

    Rhee, Y. J., Hillier, S., Pendlowski, H. & Gadd, G. M. Oct 2014 In : Chemosphere. 113, p. 17-21 5 p.

    Research output: Contribution to journalArticle

  14. Oat agriculture, cultivation and breeding targets: implications for human nutrition and health

    Stewart, D. & McDougall, G. Oct 2014 In : British Journal of Nutrition. 112 , Suppl. 2, p. S50-S57 8 p.

    Research output: Contribution to journalArticle

  15. Phosphoproteomics combined with quantitative 14-3-3-affinity capture identifies SIRT1 and RAI as novel regulators of cytosolic double-stranded RNA recognition pathway

    Öhman, T., Söderholm, S., Hintsanen, P., Välimäki, E., Lietzén, N., MacKintosh, C., Aittokallio, T., Matikainen, S. & Nyman, T. A. Oct 2014 In : Molecular & Cellular Proteomics. 13, 10, p. 2604-2617 14 p.

    Research output: Contribution to journalArticle

  16. Stem cell decisions: A twist of fate or a niche market?

    Januschke, J. & Nathke, I. Oct 2014 In : Seminars in Cell & Developmental Biology. p. 116-123

    Research output: Contribution to journalScientific review

  17. Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction

    Roche, S. L., Sherman, D. L., Dissanayake, K., Soucy, G., Desmazieres, A., Lamont, D. J., Peles, E., Julien, J-P., Wishart, T. M., Ribchester, R. R., Brophy, P. J. & Gillingwater, T. H. 17 Sep 2014 In : Journal of Neuroscience. 34, 38, p. 12904-12918 15 p.

    Research output: Contribution to journalArticle

  18. Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks

    Albergante, L., Blow, J. J. & Newman, T. J. 2 Sep 2014 In : eLife. 3, 28 p.e02863

    Research output: Contribution to journalArticle

  19. In silico identification and characterization of conserved plant microRNAs in barley

    Wu, X., Hornyik, C., Bayer, M., Marshall, D., Waugh, R. & Zhang, R. Sep 2014 In : Central European Journal of Biology. 9, 9, p. 841-852 12 p.

    Research output: Contribution to journalArticle

  20. Barley has two peroxisomal ABC transporters with multiple functions in β-oxidation

    Mendiondo, G. M., Medhurst, A., van Roermund, C. W., Zhang, X., Devonshire, J., Scholefield, D., Fernández, . J., Axcell, B., Ramsay, L., Waterham, H. R., Waugh, R., Theodoulou, F. L. & Holdsworth, M. J. Sep 2014 In : Journal of Experimental Botany. 65, 17, p. 4833-4847 15 p.

    Research output: Contribution to journalArticle

  21. Crystal structure and mechanistic investigation of the twister ribozyme

    Liu, Y., Wilson, T. J., McPhee, S. A. & Lilley, D. M. J. Sep 2014 In : Nature Chemical Biology. 10, 9, p. 739-744 6 p.

    Research output: Contribution to journalArticle

  22. Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains

    Kneuper, H., Cao, Z. P., Twomey, K. B., Zoltner, M., Jäger, F., Cargill, J. S., Chalmers, J., van der Kooi-Pol, M. M., van Dijl, J. M., Ryan, R. P., Hunter, W. N. & Palmer, T. Sep 2014 In : Molecular Microbiology. 93, 5, p. 928-943 15 p.

    Research output: Contribution to journalArticle

  23. Sequence diversity in the large subunit of RNA polymerase I contributes to Mefenoxam insensitivity in Phytophthora infestans

    Randall, E., Young, V., Sierotzki, H., Scalliet, G., Birch, P. R. J., Cooke, D. E. L., Csukai, M. & Whisson, S. C. Sep 2014 In : Molecular Plant Pathology. 15, 7, p. 664-676 13 p.

    Research output: Contribution to journalArticle

  24. The low recombining pericentromeric region of barley restricts gene diversity and evolution but not gene expression

    Baker, K., Bayer, M., Cook, N., Dreißig, S., Dhillon, T., Russell, J., Hedley, P. E., Morris, J., Ramsay, L., Colas, I., Waugh, R., Steffenson, B., Milne, I., Stephen, G., Marshall, D. & Flavell, A. J. Sep 2014 In : Plant Journal. 79, 6, p. 981-992 12 p.

    Research output: Contribution to journalArticle

  25. Screening-based discovery of Aspergillus fumigatus plant-type chitinase inhibitors

    Lockhart, D. E. A., Schuettelkopf, A., Blair, D. E. & van Aalten, D. M. F. 25 Aug 2014 In : FEBS Letters. 588, 17, p. 3282-3290 9 p.

    Research output: Contribution to journalArticle

  26. Direct contacts with colon cancer cells regulate the differentiation of bone marrow mesenchymal stem cells into tumor associated fibroblasts

    Peng, Y., Li, Z., Yang, P., Newton, I. P., Ren, H., Zhang, L., Wu, H. & Li, Z. 15 Aug 2014 In : Biochemical and Biophysical Research Communications. 451, 1, p. 68-73 6 p.

    Research output: Contribution to journalArticle

  27. Structure-based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1

    Khalaf, A. I., Huggan, J. K., Suckling, C. J., Gibson, C. L., Stewart, K., Giordani, F., Barrett, M. P., Wong, P. E., Barrack, K. L. & Hunter, W. N. 14 Aug 2014 In : Journal of Medicinal Chemistry. 57, 15, p. 6479-6494 16 p.

    Research output: Contribution to journalArticle

  28. Further occurrences of Dohrniphora cornuta (Bigot) (Diptera, Phoridae) in forensic cases indicate likely importance of this species in future cases

    Disney, R. H. L., Garcia-Rojo, A., Lindström, A. & Manlove, J. D. Aug 2014 In : Forensic Science International. 241, p. e20-e22

    Research output: Contribution to journalArticle

  29. Helium: visualization of large scale plant pedigrees

    Shaw, P. D., Graham, M., Kennedy, J., Milne, I. & Marshall, D. F. Aug 2014 In : BMC Bioinformatics. 15, 15 p.259

    Research output: Contribution to journalArticle

  30. Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo

    Olivera-Martinez, I., Schurch, N., Li, R., Song, J., Halley, P. A., Das, R. M., Burt, D. W., Barton, G. J. & Storey, K. G. Aug 2014 In : Development. 141, 16, p. 3266-3276 11 p.

    Research output: Contribution to journalArticle

  31. Safety and feasibility of retrieval of intragastric balloon followed by antiobesity surgery on the same day

    Young, J. A., Alijani, A., Patil, P. V. & Shimi, S. M. Aug 2014 In : Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 24, 4, p. e137-e139 3 p.

    Research output: Contribution to journalArticle

  32. Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung

    McMillan, S. J., Sharma, R. S., Richards, H. E., Hegde, V. & Crocker, P. R. 18 Jul 2014 In : Journal of Biological Chemistry. 289, 29, p. 20370-20376 7 p.

    Research output: Contribution to journalArticle

  33. The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters

    Alessi, D. R., Zhang, J., Khanna, A., Hochdörfer, T., Shang, Y. & Kahle, K. T. 15 Jul 2014 In : Science Signaling. 7, 334, 10 p.re3

    Research output: Contribution to journalArticle

  34. Algae

    Raven, J. A. & Giordano, M. 7 Jul 2014 In : Current Biology. 24, 13, p. R590-R595 6 p.

    Research output: Contribution to journalArticle

  35. Extremely short-duration high-intensity training substantially improves the physical function and self-reported health status of elderly adults

    Adamson, S. B., Lorimer, R., Cobley, J. N. & Babraj, J. Jul 2014 In : Journal of the American Geriatrics Society. 62, 7, p. 1380-1 2 p.

    Research output: Contribution to journalArticle

  36. Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

    Cole, C., Kroboth, K., Schurch, N. J., Sandilands, A., Sherstnev, A., O'Regan, G. M., Watson, R. M., McLean, W. H. I., Barton, G. J., Irvine, A. D. & Brown, S. J. Jul 2014 In : Journal of Allergy and Clinical Immunology. 134, 1, p. 82-91 10 p.

    Research output: Contribution to journalArticle

  37. The contribution of dormant origins to genome stability: from cell biology to human genetics

    Alver, R. C., Chadha, G. S. & Blow, J. J. Jul 2014 In : DNA Repair. 19, p. 182-189 8 p.

    Research output: Contribution to journalArticle

  38. Glycogen Synthase Kinase (GSK) 3β phosphorylates and protects nuclear myosin 1c from proteasome-mediated degradation to activate rDNA transcription in early G1 cells

    Sarshad, A. A., Corcoran, M., Al-Muzzaini, B., Borgonovo-Brandter, L., Von Euler, A., Lamont, D., Visa, N. & Percipalle, P. 5 Jun 2014 In : PLoS Genetics. 10, 6, 17 p.e1004390

    Research output: Contribution to journalArticle

  39. PDK1 controls upstream PI3K expression and PIP3 generation

    Dieterle, A. M., Böhler, P., Keppeler, H., Alers, S., Berleth, N., Drießen, S., Hieke, N., Pietkiewicz, S., Löffler, A. S., Peter, C., Gray, A., Leslie, N. R., Shinohara, H., Kurosaki, T., Engelke, M., Wienands, J., Bonin, M., Wesselborg, S. & Stork, B. 5 Jun 2014 In : Oncogene. 33, 23, p. 3043-3053 11 p.

    Research output: Contribution to journalArticle

  40. A conserved and essential basic region mediates tRNA binding to the Elp1 subunit of the Saccharomyces cerevisiae Elongator complex

    Di Santo, R., Bandau, S. & Stark, M. J. R. Jun 2014 In : Molecular Microbiology. 92, 6, p. 1227-1242 16 p.

    Research output: Contribution to journalArticle

  41. Immune diseases caused by mutations in kinases and components of the ubiquitin system

    Cohen, P. Jun 2014 In : Nature Immunology. 15, 6, p. 521-529 9 p.

    Research output: Contribution to journalArticle

  42. Low levels of ribosomal RNA partly account for the very high photosynthetic phosphorus-use efficiency of Proteaceae species

    Sulpice, R., Ishihara, H., Schlereth, A., Cawthray, G. R., Encke, B., Giavalisco, P., Ivakov, A., Arrivault, S., Jost, R., Krohn, N., Kuo, J., Laliberté, E., Pearse, S. J., Raven, J. A., Scheible, W-R., Teste, F., Veneklaas, E. J., Stitt, M. & Lambers, H. Jun 2014 In : Plant, Cell & Environment. 37, 6, p. 1276-1298 23 p.

    Research output: Contribution to journalArticle

  43. The TLR and IL-1 signalling network at a glance

    Cohen, P. Jun 2014 In : Journal of Cell Science. 127, 11, p. 2383-2390 8 p.

    Research output: Contribution to journalArticle

  44. The RNA helicase/transcriptional co-regulator, p68 (DDX5), stimulates expression of oncogenic protein kinase, Polo-like kinase-1 (PLK1), and is associated with elevated PLK1 levels in human breast cancers

    Iyer, R. S., Nicol, S. M., Quinlan, P. R., Thompson, A. M., Meek, D. W. & Fuller-Pace, F. V. 1 May 2014 In : Cell cycle (Georgetown, Tex.). 13, 9, p. 1413-1423 11 p.

    Research output: Contribution to journalArticle

  45. Biosorption: current perspectives on concept, definition and application

    Fomina, M. & Gadd, G. M. May 2014 In : Bioresource Technology. 160, p. 3-14 12 p.

    Research output: Contribution to journalArticle

  46. VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase

    Baron, Y., Pedrioli, P. G., Tyagi, K., Johnson, C., Wood, N. T., Fountaine, D., Wightman, M. & Alexandru, G. May 2014 In : BMC Biology. 12, 20 p.39

    Research output: Contribution to journalArticle

  47. Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies

    Pearce, O. M. T., Läubli, H., Verhagen, A., Secrest, P., Zhang, J., Varki, N. M., Crocker, P. R., Bui, J. D. & Varki, A. 22 Apr 2014 In : Proceedings of the National Academy of Sciences of the United States of America. 111, 16, p. 5998-6003 6 p.

    Research output: Contribution to journalArticle

  48. Biochemical and genetic characterization of Trypanosoma cruzi N-myristoyltransferase

    Roberts, A. J., Torrie, L. S., Wyllie, S. & Fairlamb, A. H. 15 Apr 2014 In : Biochemical Journal. 459, 2, p. 323-332 10 p.

    Research output: Contribution to journalArticle

  49. Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells

    Hawley, S. A., Ross, F. A., Gowans, G. J., Tibarewal, P., Leslie, N. R. & Hardie, D. G. 15 Apr 2014 In : Biochemical Journal. 459, 2, p. 275-287 13 p.

    Research output: Contribution to journalArticle

  50. Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy

    Wishart, T. M. , Mutsaers, C. A. , Riessland, M. , Reimer, M. M. , Hunter, G. , Hannam, M. L. , Eaton, S. L. , Fuller, H. R. , Roche, S. L. , Somers, E. , Morse, R. , Young, P. J. , Lamont, D. J. , Hammerschmidt, M. , Joshi, A. , Hohenstein, P. , Morris, G. E. , Parson, S. H. , Skehel, P. A. , Becker, T. & 4 others Robinson, I. M., Becker, C. G., Wirth, B. & Gillingwater, T. H. 1 Apr 2014 In : Journal of Clinical Investigation. 124, 4, p. 1821-1834 14 p.

    Research output: Contribution to journalArticle

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