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  1. The effect of dietary intervention on the metabolic and behavioural impairments generated by short term high fat feeding in the rat

    McNeilly, A. D., Gao, A., Hill, A. Y., Gomersall, T., Balfour, D. J. K., Sutherland, C. & Stewart, C. A. 1 Dec 2016 In : Physiology & Behavior. 167, p. 100-109 10 p.

    Research output: Contribution to journalArticle

  2. Isolated recessive nail dysplasia caused by FZD6 mutations: report of three families and review of the literature

    Kasparis, C., Reid, D., Wilson, N. J., Okur, V., Cole, C., Hansen, C. D., Bosse, K., Betz, R. C., Khan, M. & Smith, F. J. D. Dec 2016 In : Clinical and Experimental Dermatology. 41, 8, p. 884-889 6 p.

    Research output: Contribution to journalArticle

  3. An mTORC1/AKT1/Cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in Atopic Dermatitis

    Naeem, A. S., Tommasi, C., Cole, C., Brown, S. J., Zhu, Y., Way, B., Willis Owen, S. A. G., Moffatt, M., Cookson, W. O., Harper, J. I., Di, W. L., Brown, S. J., Reinheckel, T. & O'Shaughnessy, R. F. L. 29 Nov 2016 In : Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalArticle

  4. The feasibility of micro-ultrasound as a tool to image peripheral nerves

    Chandra, A., Eisma, R., Felts, P., Munirama, S., Corner, G. A., Demore, C. E. M. & McLeod, G. 29 Nov 2016 In : Anaesthesia. 7 p.

    Research output: Contribution to journalArticle

  5. Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

    Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J. 20 Nov 2016 New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January, p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  6. Atopic dermatitis patients with filaggrin loss-of-function mutations show good but lower responses to immunosuppressive treatment

    Roekevisch, E., Leeflang, M. M. G., Schram, M. E., Campbell, L. E., Irwin McLean, W. H., Kezic, S., Bos, J. D., Spuls, P. I. & Middelkamp-Hup, M. A. 19 Nov 2016 In : British Journal of Dermatology.

    Research output: Contribution to journalLetter

  7. A novel KRT6A mutation in a case of pachyonychia congenita from India

    Tiwary, A. K., Wilson, N. J., Schwartz, M. E. & Smith, F. J. D. 11 Nov 2016 In : Indian Journal of Dermatology, Venereology and Leprology.

    Research output: Contribution to journalLetter

  8. Combined effect of educational status and cardiovascular risk factors on the incidence of coronary heart disease and stroke in European cohorts: Implications for prevention

    Veronesi, G., Tunstall-Pedoe, H., Ferrario, M. M., Kee, F., Kuulasmaa, K., Chambless, L. E., Amouyel, P., Arveiler, D., Bobak, M., Ferrieres, J., Giampaoli, S., Jørgensen, T., Peters, A., Salomaa, V., Soderberg, S., Tamosiunas, A., Cesana, G. & for the MORGAM Project 11 Nov 2016 10 p.

    Research output: Contribution to journalArticle

  9. How can we optimise inhaled beta2 agonist dose as 'reliever' medicine for wheezy pre-school children?: Study protocol for a randomised controlled trial

    Mukhopadhyay, S., Seddon, P., Earl, G., Wileman, E., Symes, L., Olden, C., Alberti, C., Bremner, S., Lansley, A., Palmer, C. N. A. & Beydon, N. 11 Nov 2016 In : Trials. 17, 9 p., 541

    Research output: Contribution to journalArticle

  10. Your professionalism is not my professionalism: congruence and variance in the views of medical students and faculty about professionalism

    Sattar, K., Roff, S. & Meo, S. A. 8 Nov 2016 In : BMC Medical Education. 16, 7 p., 285

    Research output: Contribution to journalArticle

  11. Defining drug response for stratified medicine

    Lonergan, M., Senn, S. J., McNamee, C., Daly, A. K., Sutton, R., Hattersley, A., Pearson, E. & Pirmohamed, M. 3 Nov 2016 In : Drug Discovery Today. 7 p.

    Research output: Contribution to journalReview article

  12. Analysis of physical pore space characteristics of two pyrolytic biochars and potential as microhabitat

    Schnee, L. S., Knauth, S., Hapca, S., Otten, W. & Eickhorst, T. Nov 2016 In : Plant and Soil. 408, 1, p. 357-368 12 p.

    Research output: Contribution to journalArticle

  13. Systematic population screening, using biomarkers and genetic testing, identifies 2.5% of the U.K. pediatric diabetes population with monogenic diabetes

    Shepherd, M., Shields, B., Hammersley, S., Hudson, M., McDonald, T. J., Colclough, K., Oram, R. A., Knight, B., Hyde, C., Cox, J., Mallam, K., Moudiotis, C., Smith, R., Fraser, B., Robertson, S., Greene, S., Ellard, S., Pearson, E. R., Hattersley, A. T. & on behalf of the UNITED Team Nov 2016 In : Diabetes Care. 39, 11, p. 1879-1888 10 p.

    Research output: Contribution to journalArticle

  14. An evidence-based treatment algorithm for colorectal polyp cancers: results from the Scottish Screen-detected Polyp Cancer Study (SSPoCS)

    Steele, R. J. C. & 21 others Richards, C. H., Ventham, N. T., Mansouri, D., Wilson, M., Ramsay, G., Mackay, C. D., Parnaby, C. N., Smith, D., On, J., Speake, D., McFarlane, G., Neo, Y. N., Aitken, E., Forrest, C., Knight, K., McKay, A., Nair, H., Mulholland, C., Robertson, J. H., Carey, F. A. & on behalf of the Scottish Surgical Research Group 27 Oct 2016 In : Gut. 8 p.

    Research output: Contribution to journalArticle

  15. 'Thinking that somebody's going to delay [a tonsillectomy] for one to two years is quite horrifying really': a qualitative feasibility study for the NAtional Trial of Tonsillectomy IN Adults (NATTINA Part 2)

    McSweeney, L. A., O'Hara, J. T., Rousseau, N. S., Stocken, D. D., Sullivan, F., Vale, L., Wilkes, S., Wilson, J. A. & Haighton, C. A. 19 Oct 2016 In : Clinical Otolaryngology. 6 p.

    Research output: Contribution to journalArticle

  16. Plasma and blood viscosity in the prediction of cardiovascular disease and mortality in the Scottish Heart Health Extended Cohort Study

    Peters, S. A. E., Woodward, M., Rumley, A., Tunstall-Pedoe, H. D. & Lowe, G. D. O. 17 Oct 2016 7 p.

    Research output: Contribution to journalArticle

  17. Six years' experience of grenz ray therapy for the treatment of inflammatory skin conditions

    Fenton, L. & Dawe, R. S. 16 Oct 2016 In : Clinical and Experimental Dermatology. 7 p.

    Research output: Contribution to journalArticle

  18. Erratum to: The effect of a performance-based intra-procedural checklist on a simulated emergency laparoscopic task in novice surgeons

    Boghdady, M. E., Tang, B. & Alijani, A. 5 Oct 2016 In : Surgical Endoscopy. 1 p.

    Research output: Contribution to journalArticle

  19. Laparoscopic assisted colonoscopy: results and follow up endoscopic success

    Quyn, A. J., Vujovic, Z., Ziyaie, D., Steele, R. J. C. & Campbell, K. L. 4 Oct 2016 In : Colorectal Disease. 18, 10, p. 0376-0379 4 p.

    Research output: Contribution to journalArticle

  20. The ClearPET/XPAD prototype: Development of a simultaneous PET/CT scanner for mice

    Hamonet, M., Dupont, M., Fabiani, T., Cassol, F., Boursier, Y., Bonissent, A., Debarbieux, F., Pottier, G., Bidaut, L. & Morel, C. 3 Oct 2016 2015 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2015. Institute of Electrical and Electronics Engineers Inc., p. 1-3 3 p. 7582074

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  21. A hydraulically driven colonoscope

    Coleman, S. A., Tapia Siles, S. C., Pakleppa, M., Vorstius, J. B., Keatch, R. P., Tang, B. & Cuschieri, A. Oct 2016 In : Surgical Endoscopy. 30, 10, p. 4515-4524 11 p.

    Research output: Contribution to journalArticle

  22. Trends in type 2 diabetes incidence and mortality in Scotland between 2004 and 2013

    Read, S. H., Kerssens, J. J., McAllister, D. A., Colhoun, H. M., Fischbacher, C. M., Lindsay, R. S., McCrimmon, R. J., McKnight, J. A., Petrie, J. R., Sattar, N., Wild, S. H. & On behalf of the Scottish Diabetes Research Network Epidemiology Group Oct 2016 In : Diabetologia. 59, 10, p. 2106-2113 8 p.

    Research output: Contribution to journalArticle

  23. Childhood obesity in relation to poor asthma control and exacerbation: a meta-analysis

    Ahmadizar, F., Vijverberg, S. J. H., Arets, H. G. M., de Boer, A., Lang, J. E., Kattan, M., Palmer, C. N. A., Mukhopadhyay, S., Turner, S. & Maitland-van der Zee, A. H. 30 Sep 2016 In : European Respiratory Journal. p. 1063-1073

    Research output: Contribution to journalArticle

  24. A prospective comparison of ER, PR, Ki67 and gene expression in paired sequential core biopsies of primary, untreated breast cancer

    Hadad, S. M., Jordan, L. B., Roy, P. G., Purdie, C. A., Iwamoto, T., Pusztai, L., Moulder-Thompson, S. L. & Thompson, A. M. 22 Sep 2016 In : BMC Cancer. 16, p. 1-11 11 p., 745

    Research output: Contribution to journalArticle

  25. Tumour suppressor gene (CDKNA2) status on chromosome 9p in resected renal tissue improves prognosis of localised kidney cancer

    El-Mokadem, I., Kidd, T., Pratt, N., Fleming, S. & Nabi, G. 22 Sep 2016 In : Oncotarget. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  26. Progress and divergence in palliative care education for medical students: A comparative survey of UK course structure, content, delivery, contact with patients and assessment of learning

    Walker, S., Gibbins, J., Barclay, S., Adams, A., Paes, P., Chandratilake, M., Gishen, F., Lodge, P. & Wee, B. 12 Sep 2016 In : Palliative Medicine. 30, 9, p. 834-842 9 p.

    Research output: Contribution to journalArticle

  27. Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

    Khan, F. , Belch, J. & 25 others Gonçalves, I., Edsfeldt, A., Colhoun, H. M., Shore, A. C., Palombo, C., Natali, A., Fredrikson, G. N., Björkbacka, H., Wigren, M., Bengtsson, E., Östling, G., Aizawa, K., Casanova, F., Persson, M., Gooding, K., Gates, P., Looker, H. C., Adams, F., Pinnola, S., Venturi, E., Kozakova, M., Gan, L-M., Schnecke, V., Nilsson, J. & on behalf of the SUMMIT consortium 5 Sep 2016 In : BMC Cardiovascular Disorders. 16, p. 1-10 10 p., 171

    Research output: Contribution to journalArticle

  28. Skin microbiome prior to development of atopic dermatitis: early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year

    Kennedy, E. A., Connolly, J., O.'B. Hourihane, J., Fallon, P. G., McLean, W. H. I., Murray, D., Jo, J-H., Segre, J. A., Kong, H. H. & Irvine, A. D. 5 Sep 2016 In : Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalArticle

  29. Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

    Postmus, I. , Warren, H. R. , Trompet, S. , Arsenault, B. J. , Avery, C. L. , Bis, J. C. , Chasman, D. I. , de Keyser, C. E. , Deshmukh, H. A. , Evans, D. S. , Feng, Q. , Li, X. , Smit, R. A. J. , Smith, A. V. , Sun, F. , Taylor, K. D. , Arnold, A. M. , Barnes, M. R. , Barratt, B. J. & 69 others Betteridge, J., Boekholdt, S. M., Boerwinkle, E., Buckley, B. M., Chen, Y-D. I., de Craen, A. J. M., Cummings, S. R., Denny, J. C., Dubé, M. P., Durrington, P. N., Eiriksdottir, G., Ford, I., Guo, X., Harris, T. B., Heckbert, S. R., Hofman, A., Hovingh, G. K., Kastelein, J. J. P., Launer, L. J., Liu, C-T., Liu, Y., Lumley, T., McKeigue, P. M., Munroe, P. B., Neil, A., Nickerson, D. A., Nyberg, F., O'Brien, E., O'Donnell, C. J., Post, W., Poulter, N., Vasan, R. S., Rice, K., Rich, S. S., Rivadeneira, F., Sattar, N., Sever, P., Shaw-Hawkins, S., Shields, D. C., Slagboom, P. E., Smith, N. L., Smith, J. D., Sotoodehnia, N., Stanton, A., Stott, D. J., Stricker, B. H., Stürmer, T., Uitterlinden, A. G., Wei, W-Q., Westendorp, R. G. J., Whitsel, E. A., Wiggins, K. L., Wilke, R. A., Ballantyne, C. M., Colhoun, H. M., Cupples, L. A., Franco, O. H., Gudnason, V., Hitman, G., Palmer, C. N. A., Psaty, B. M., Ridker, P. M., Stafford, J. M., Stein, C. M., Tardif, J-C., Caulfield, M. J., Jukema, J. W., Rotter, J. I. & Krauss, R. M. 1 Sep 2016 In : Journal of Medical Genetics. 11 p.

    Research output: Contribution to journalArticle

  30. The effect of a performance based intra-procedural checklist on a simulated emergency laparoscopic task in novice surgeons

    El Boghdady, M., Tang, B. & Alijani, A. 1 Sep 2016 In : Surgical Endoscopy. 5 p.

    Research output: Contribution to journalArticle

  31. 30-day mortality after systemic anticancer treatment for breast and lung cancer in England: a population-based, observational study

    Wallington, M., Saxon, E. B., Bomb, M., Smittenaar, R., Wickenden, M., McPhail, S., Rashbass, J., Chao, D., Dewar, J., Talbot, D., Peake, M., Perren, T., Wilson, C. & Dodwell, D. Sep 2016 In : Lancet Oncology. 17, 9, p. 1203-1216 14 p.

    Research output: Contribution to journalArticle

  32. A cadaver study comparing spread of dye and nerve involvement after three different quadratus lumborum blocks

    Carline, L., McLeod, G. A. & Lamb, C. Sep 2016 In : British Journal of Anaesthesia. 117, 3, p. 387-394 18 p.

    Research output: Contribution to journalArticle

  33. MEK is a therapeutic and chemopreventative target in squamous cell carcinoma

    Adelmann, C. H., Truong, K. A., Liang, R. J., Bansal, V., Gandee, L., Saporito, R., Lee, W., Du, L., Nicholas, C., Napoli, M., Mino, B., South, A. P., Proby, C. M., Leigh, I. M., Coarfa, C., Flores, E. R. & Tsai, K. Y. Sep 2016 In : Journal of Investigative Dermatology. 136, 9, p. 1920-1924 5 p.

    Research output: Contribution to journalLetter

  34. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

    Cameron, A. R., Morrison, V., Levin, D., Mohan, M., Forteath, C., Beall, C., McNeilly, A. D., Balfour, D. J. K., Savinko, T., Wong, A. K. F., Viollet, B., Sakamoto, K., Fagerholm, S. C., Foretz, M., Lang, C. C. & Rena, G. 19 Aug 2016 In : Circulation Research. 119, 5, p. 652-665 14 p.

    Research output: Contribution to journalArticle

  35. Mutations in the mevalonate pathway genes in Chinese patients with porokeratosis

    Li, M., Li, Z., Wang, J., Ni, C., Sun, Z., Wilson, N. J., Zhang, J., Chen, F., Li, X., Du, X., Yu, H., Zhang, L., Smith, F. J. D., Zhang, G. & Yao, Z. 19 Aug 2016 In : Journal of the European Academy of Dermatology and Venereology. 30, 9, p. 1512-1517 6 p.

    Research output: Contribution to journalArticle

  36. tRNA methyltransferase homologue gene TRMT10A mutation in young adult-onset diabetes with intellectual disability, microcephaly and epilepsy

    Yew, T. W., McCreight, L., Colclough, K., Ellard, S. & Pearson, E. R. 17 Aug 2016 In : Diabetic Medicine. 33, 9, p. e21-e25 5 p.

    Research output: Contribution to journalArticle

  37. Focal PPK secondary to a novel KRT6C mutation (Pachyonychia congenita-K6c)

    Wee, J. S., Smith, F. J. D., Wilson, N. J. & O'Toole, E. A. 12 Aug 2016 In : Journal of the European Academy of Dermatology and Venereology. 30, 8, p. 1415-1416 2 p.

    Research output: Contribution to journalLetter

  38. Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

    Daniels, M. J. D. , Rivers-Auty, J. , Schilling, T. , Spencer, N. G. , Watremez, W. , Fasolino, V. , Booth, S. J. , White, C. S. , Baldwin, A. G. , Freeman, S. , Wong, R. , Latta, C. , Yu, S. , Jackson, J. , Fischer, N. , Koziel, V. , Pillot, T. , Bagnall, J. , Allan, S. M. & 6 others Paszek, P., Galea, J., Harte, M. K., Eder, C., Lawrence, C. B. & Brough, D. 11 Aug 2016 In : Nature Communications. 7, p. 1-10 10 p., 12504

    Research output: Contribution to journalArticle

  39. Respiratory effect of beta-blocker eye drops in asthma: population-based study and meta-analysis of clinical trials

    Morales, D. R., Dreischulte, T., Lipworth, B. J., Donnan, P. T., Jackson, C. & Guthrie, B. 8 Aug 2016 In : British Journal of Clinical Pharmacology. 82, 3, p. 814-822 9 p.

    Research output: Contribution to journalArticle

  40. The genetic architecture of type 2 diabetes

    Fuchsberger, C. , Flannick, J. , Teslovich, T. M. , Mahajan, A. , Agarwala, V. , Gaulton, K. J. , Ma, C. , Fontanillas, P. , Moutsianas, L. , McCarthy, D. J. , Rivas, M. A. , Perry, J. R. B. , Sim, X. , Blackwell, T. W. , Robertson, N. R. , Rayner, N. W. , Cingolani, P. , Locke, A. E. , Tajes, J. F. & 282 others Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B-J., Kim, Y., Kim, Y. J., Kwon, M-S., Lee, J., Lee, S., Lin, K-H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B-G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S-H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C-Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C-C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., van der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S-T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., Hrabé de Angelis, M., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A-C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J-Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M., Altshuler, D. & McCarthy, M. I. 4 Aug 2016 In : Nature. 536, p. 41-47 29 p., 18642

    Research output: Contribution to journalArticle

  41. Arterio-venous differences in cord levels of catecholamines, glucose, lactate and blood gases

    Koh, D. K. M., Hume, R., Eisenhofer, G., Watson, J. & Williams, F. L. R. 1 Aug 2016 In : Journal of Perinatal Medicine. 44, 6, p. 695-704 10 p.

    Research output: Contribution to journalArticle

  42. Reports of Perceived Adverse Events of Stimulant Medication on Cognition, Motivation, and Mood: Qualitative Investigation and the Generation of Items for the Medication and Cognition Rating Scale

    Kovshoff, H., Banaschewski, T., Buitelaar, J. K., Carucci, S., Coghill, D., Danckaerts, M., Dittmann, R. W., Falissard, B., Grimshaw, D. G., Hollis, C., Inglis, S., Konrad, K., Liddle, E., McCarthy, S., Nagy, P., Thompson, M., Wong, I. C. K., Zuddas, A. & Sonuga-Barke, E. J. S. 1 Aug 2016 In : Journal of Child and Adolescent Psychopharmacology. 26, 6, p. 537-547 11 p.

    Research output: Contribution to journalArticle

  43. Acute risk factors in fatal opioid overdoses as a result of hypoxia and cardiotoxicity. A systematic review and critical appraisal

    Baldacchino, A., Tolomeo, S., Khan, F., Humphris, G. & Carrà, G. Aug 2016 In : Heroin Addiction and Related Clinical Problems. 18, 4, p. 33-42 10 p.

    Research output: Contribution to journalReview article

  44. CREBBP mutation in human cutaneous squamous cell carcinoma

    Watt, S. A., Purdie, K. J., den Breems, N. Y., Dimon, M., Tucker, S., Arron, S. T., Mchugh, A., Xue, D. J., Dayal, J. H. S., Harwood, C. A., Leigh, I. M., Proby, C. M. & South, A. P. Aug 2016 In : Experimental Dermatology. 25, 8, p. 650-651 2 p.

    Research output: Contribution to journalLetter

  45. Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells

    Leitch, C. S., Natafji, E., Yu, C., Abdul-Ghaffar, S., Madarasingha, N., Venables, Z. C., Chu, R., Fitch, P. M., Muinonen-Martin, A. J., Campbell, L. E., McLean, W. H. I., Schwarze, J., Howie, S. E. M. & Weller, R. B. Aug 2016 In : Journal of Allergy and Clinical Immunology. 138, 2, p. 482-490.e7 16 p.

    Research output: Contribution to journalArticle

  46. Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug

    Cameron, A., Logie, L., Patel, K., Bacon, S., Forteath, C., Harthill, J., Roberts, A., Sutherland, C., Stewart, D., Viollet, B., Sakamoto, K., McDougall, G., Foretz, M. & Rena, G. Aug 2016 In : Biochimica et Biophysica Acta. Molecular Basis of Disease. 1862, 8, p. 1412-1422 11 p.

    Research output: Contribution to journalArticle

  47. Rhodiola rosea L.: from golden root to green cell factories

    Marchev, A. S., Dinkova-Kostova, A. T., György, Z., Mirmazloum, I., Aneva, I. Y. & Georgiev, M. I. Aug 2016 In : Phytochemistry Reviews. 15, 4, p. 515-536 22 p.

    Research output: Contribution to journalArticle

  48. SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models

    Dinkova-Kostova, A. T. & 23 others Quinti, L., Casale, M., Moniot, S., Pais, T. F., Van Kanegan, M. J., Kaltenbach, L. S., Pallos, J., Lim, R. G., Naidu, S. D., Runne, H., Meisel, L., Rauf, N. A., Leyfer, D., Maxwell, M. M., Saiah, E., Landers, J. E., Luthi-Carter, R., Abagyan, R., Steegborn, C., Marsh, J. L., Lo, D. C., Thompson, L. M. & Kazantsev, A. G. 21 Jul 2016 In : Cell Chemical Biology. 23, 7, p. 849-861 13 p.

    Research output: Contribution to journalArticle

  49. Feedback in surgical education

    El Boghdady, M. & Alijani, A. 15 Jul 2016 In : Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 6 p.

    Research output: Contribution to journalArticle

  50. Expression of P53 and isoforms in bening and malignant lesions of the head and neck

    Trovato, M., Ruggeri, R. M., Guzzo, E., Certo, R., Alibrandi, A., Scifo, S., Scardigno, M., Vitarelli, E., Arena, G., Gambadoro, O., Catalano, N., Bourdon, J. C., Galletti, B., Galletti, F. & Cavallari, V. 14 Jul 2016 In : Histology and Histopathology. 11802

    Research output: Contribution to journalArticle

  51. The experiences of doctors across the trainee-trained doctor transition: a longitudinal audiodiary study

    Gordon, L., Jindal-Snape, D., Morrison, J., Needham, G., Seibert, S. & Rees, C. 7 Jul 2016

    Research output: Contribution to conferencePaper

  52. Safety, complications and patients' acceptance of Mohs micrographic surgery (MMS) under local anaesthesia - results from the UK MAPS (Mohs Acceptance and Patient Safety) Collaboration Group

    Hussain, W., Affleck, A., Al-Niaimi, F., Cooper, A., Craythorne, E., Fleming, C., Ghura, V., Langtry, J., Lawrence, C., Loghdey, S., Naysmith, L., Oliphant, T., Rahim, R., Rice, S., Sivaramkrishan, M., Stables, G., Varma, S. & Mallipeddi, R. 5 Jul 2016 In : British Journal of Dermatology.

    Research output: Contribution to journalLetter

  53. ADHD symptoms in children aged 5 to 15 years in Zhabei District, Shanghai

    Jin, W. L., Li, G. Z., Du, Y. S., Coghill, D., Au, S. & Zhong, X. Y. 1 Jul 2016 In : European Journal of Psychiatry. 30, 3, p. 173-182 10 p.

    Research output: Contribution to journalArticle

  54. An empirical comparison of joint and stratified frameworks for studying G x E interactions: systolic blood pressure and smoking in the CHARGE gene-lifestyle interactions working group

    Smith, B. H. & 57 others Sung, Y. J., Winkler, T. W., Manning, A. K., Aschard, H., Gudnason, V., Harris, T. B., Smith, A. V., Boerwinkle, E., Brown, M. R., Morrison, A. C., Fornage, M., Lin, L. A., Richard, M., Bartz, T. M., Psaty, B. M., Hayward, C., Polasek, O., Marten, J., Rudan, I., Feitosa, M. F., Kraja, A. T., Province, M. A., Deng, X., Fisher, V. A., Zhou, Y., Bielak, L. F., Smith, J., Huffman, J. E., Padmanabhan, S., Ding, J., Liu, Y., Lohman, K., Bouchard, C., Rankinen, T., Rice, T. K., Arnett, D., Schwander, K., Guo, X., Palmas, W., Rotter, J. I., Alfred, T., Bottinger, E. P., Loos, R. J. F., Amin, N., Franco, O. H., van Duijn, C. M., Vojinovic, D., Chasman, D. I., Ridker, P. M., Rose, L. M., Kardia, S., Zhu, X., Rice, K., Borecki, I. B., Rao, D. C., Gauderman, W. J. & Cupples, L. A. Jul 2016 In : Genetic Epidemiology. 40, 5, p. 404-415 12 p., 21978

    Research output: Contribution to journalArticle

  55. Liver retraction system by C3-muco-adhesive polymer films for laparoscopic surgery

    Aldeghaither, S., Tang, B., Alijani, A., McLean, D., Wright, E., Wang, Z., Tait, I. & Cuschieri, A. Jul 2016 In : Surgical Endoscopy. 30, 7, p. 2834-2839 6 p.

    Research output: Contribution to journalArticle

  56. Racquet string tension directly affects force experienced at the elbow: implications for the development of lateral epicondylitis in tennis players

    Mohandhas, B. R., Makaram, N., Drew, T. S., Wang, W., Arnold, G. P. & Abboud, R. J. Jul 2016 In : Shoulder and Elbow. 8, 3, p. 184-191 8 p.

    Research output: Contribution to journalArticle

  57. Transcutaneous Electrical Nerve Stimulation improves walking performance in patients with intermittent claudication

    Seenan, C., McSwiggan, S., Roche, P. A., Tan, C-W., Mercer, T. & Belch, J. J. F. Jul 2016 In : European Journal of Cardiovascular Nursing. 31, 4, p. 323-330 8 p.

    Research output: Contribution to journalArticle

  58. Development and preliminary psychometric properties of the Care Experience Feedback Improvement Tool (CEFIT)

    Beattie, M., Shepherd, A., Lauder, W., Atherton, I., Cowie, J. & Murphy, D. J. 14 Jun 2016 In : BMJ Open. 6, 6, 13 p., e010101

    Research output: Contribution to journalArticle

  59. Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer

    Schmid, P. , Pinder, S. E. , Wheatley, D. , Macaskill, J. , Zammit, C. , Hu, J. , Price, R. , Bundred, N. , Hadad, S. , Shia, A. , Sarker, S. J. , Lim, L. , Gazinska, P. , Woodman, N. , Korbie, D. , Trau, M. , Mainwaring, P. , Gendreau, S. , Lackner, M. R. & 7 others Derynck, M., Wilson, T. R., Butler, H., Earl, G., Parker, P., Purushotham, A. & Thompson, A. 10 Jun 2016 In : Journal of Clinical Oncology. 34, 17, p. 1987-1994 8 p.

    Research output: Contribution to journalArticle

  60. Does advancing male age influence the expression levels and localisation patterns of phospholipase C zeta (PLCζ) in human sperm?

    Yeste, M., Jones, C., Amdani, S. N., Yelumalai, S., Mounce, G., Martins da Silva, S. J., Child, T. & Coward, K. 8 Jun 2016 In : Scientific Reports. 6, 9 p., 27543

    Research output: Contribution to journalArticle

  61. Common Creatine Kinase gene mutation results in falsely reassuring CK levels in muscle disorders

    Wallace, B., Siddiqui, M. K., Palmer, C. N. A. & George, J. 1 Jun 2016 In : QJM : an International Journal of Medicine. 109, 6, p. 413-414 3 p.

    Research output: Contribution to journalArticle

  62. Medical humanities: A closer look at learning

    Patterson, A., Sharek, D., Hennessy, M., Phillips, M. & Schofield, S. 1 Jun 2016 In : Medical Humanities. 42, 2, p. 115-120 6 p.

    Research output: Contribution to journalArticle

  63. Genome-wide analysis of over 106  000 individuals identifies 9 neuroticism-associated loci

    Smith, B. H. & 31 others Smith, D. J., Escott-Price, V., Davies, G., Bailey, M. E. S., Colodro-Conde, L., Ward, J., Vedernikov, A., Marioni, R., Cullen, B., Lyall, D., Hagenaars, S. P., Liewald, D. C. M., Luciano, M., Gale, C. R., Ritchie, S. J., Hayward, C., Nicholl, B., Bulik-Sullivan, B., Adams, M., Couvy-Duchesne, B., Graham, N., Mackay, D., Evans, J., Porteous, D. J., Medland, S. E., Martin, N. G., Holmans, P., McIntosh, A. M., Pell, J. P., Deary, I. J. & O'Donovan, M. C. Jun 2016 In : Molecular Psychiatry. 21, 6, p. 749-757 9 p.

    Research output: Contribution to journalArticle

  64. How well do contoured superior midshaft clavicle plates fit the clavicle?: A cadaveric study

    Malhas, A. M., Skarparis, Y. G., Sripada, S., Soames, R. W. & Jariwala, A. C. Jun 2016 In : Journal of Shoulder and Elbow Surgery. 25, 6, p. 954-959 6 p.

    Research output: Contribution to journalArticle

  65. In vivo validation of spatio-temporal liver motion prediction from motion tracked on MR thermometry images

    Tanner, C., Zur, Y., French, K., Samei, G., Strehlow, J., Sat, G., McLeod, H., Houston, G., Kozerke, S., Székely, G., Melzer, A. & Preusser, T. Jun 2016 In : International Journal of Computer Assisted Radiology and Surgery. 11, 6, p. 1143-1152 10 p.

    Research output: Contribution to journalArticle

  66. Living well with dementia: enhancing dignity and quality of life, using a novel intervention, Dignity Therapy

    Johnston, B., Lawton, S., Mccaw, C., Law, E., Murray, J., Gibb, J., Pringle, J., Munro, G. & Rodriguez, C. Jun 2016 In : International Journal of Older People Nursing. 11, 2, p. 107-120 8 p.

    Research output: Contribution to journalArticle

  67. Methotrexate in psoriasis under real-world conditions: long-term efficacy and tolerability

    West, J., Ogston, S., Palmer, C., Fleming, C., Dawe, R., Kumar, V., Waterston, S. & Foerster, J. Jun 2016 In : British Journal of Dermatology. 174, 6, p. 1407-1410 4 p., 14452

    Research output: Contribution to journalLetter

  68. Exosome-mediated transfer from the tumor microenvironment increases TGFβ signaling in squamous cell carcinoma

    Languino, L. R., Singh, A., Prisco, M., Inman, G. J., Luginbuhl, A., Curry, J. M. & South, A. P. 30 May 2016 In : American Journal of Translational Research. 8, 5, p. 2432-2437 6 p.

    Research output: Contribution to journalArticle

  69. Connexin30.2: In vitro interaction with connexin36 in hela cells and expression in AII amacrine cells and intrinsically photosensitive ganglion cells in the mouse retina

    Meyer, A., Tetenborg, S., Greb, H., Segelken, J., Dorgau, B., Weiler, R., Hormuzdi, S. G., Janssen-Bienhold, U. & Dedek, K. 27 May 2016 In : Frontiers in Molecular Neuroscience. 9, MAY, 17 p., 36

    Research output: Contribution to journalArticle

  70. Outcome of phacoemulsification and intraocular lens implantion in eyes with pseudoexfoliation and weak zonules

    Shingleton, B. J., Neo, Y. N., Cvintal, V., Shaikh, A. M., Liberman, P. & O'Donoghue, M. W. 27 May 2016 In : Acta Ophthalmologica. 6 p., 13110

    Research output: Contribution to journalArticle

  71. Thyroxine replacement: a clinical endocrinologist’s viewpoint

    Eligar, V., Taylor, P. N., Okosieme, O. E., Leese, G. P. & Dayan, C. M. 27 May 2016 In : Annals of Clinical Biochemistry. 53, 4, p. 421-433 13 p.

    Research output: Contribution to journalArticle

  72. Simulation training for critical care

    Shippey, B. & Nimmo, G. 26 May 2016 Oxford textbook of critical care. Webb, A., Angus, D., Finfer, S., Gattinoni, L. & Singer, M. (eds.). 2nd ed. Oxford: Oxford University Press, p. 60-63 4 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  73. Evidence-based guidelines for treating bipolar disorder: Revised third edition recommendations from the British Association for Psychopharmacology

    Goodwin, G. M. , Haddad, P. M. , Ferrier, I. N. , Aronson, J. K. , Barnes, T. R. H. , Cipriani, A. , Coghill, D. R. , Fazel, S. , Geddes, J. R. , Grunze, H. , Holmes, E. A. , Howes, O. , Hudson, S. , Hunt, N. , Jones, I. , MacMillan, I. C. , McAllister-Williams, H. , Miklowitz, D. R. , Morriss, R. & 8 others Munafò, M., Paton, C., Saharkian, B. J., Saunders, K. E. A., Sinclair, J. M. A., Taylor, D., Vieta, E. & Young, A. H. 10 May 2016 In : Journal of Psychopharmacology. 30, 6, p. 495-553 59 p.

    Research output: Contribution to journalArticle

  74. Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD

    Rabinovich, R. A., Miller, B. E., Wrobel, K., Ranjit, K., Williams, M. C., Drost, E., Edwards, L. D., Lomas, D. A., Rennard, S. I., Agustí, A., Tal-Singer, R., Vestbo, J., Wouters, E. F. M., John, M., Van Beek, E. J. R., Murchison, J. T., Bolton, C. E., Macnee, W. & Huang, J. T. J. 1 May 2016 In : European Respiratory Journal. 47, 5, p. 1365-1373 9 p.

    Research output: Contribution to journalArticle

  75. Can antioxidant-rich blackcurrant juice drink consumption improve photoprotection against ultraviolet radiation?

    Ray, S., Belch, J. J., Craigie, A. M., Khan, F., Kennedy, G., Hill, A., Barton, K. L., Dawe, R. S. & Ibbotson, S. H. May 2016 In : British Journal of Dermatology. 174, 5, p. 1101-1103 3 p.

    Research output: Contribution to journalLetter

  76. Development and validation of a model to predict absolute vascular risk reduction by moderate-intensity statin therapy in individual patients with type 2 diabetes mellitus

    Kaasenbrood, L., Poulter, N. R., Sever, P. S., Colhoun, H. M., Livingstone, S. J., Boekholdt, S. M., Pressel, S. L., Davis, B. R., Van Der Graaf, Y. & Visseren, F. L. J. May 2016 In : Circulation: Cardiovascular Quality and Outcomes. 9, 3, p. 213-221 9 p.

    Research output: Contribution to journalArticle

  77. Nrf2 activation in the treatment of neurodegenerative diseases: A focus on its role in mitochondrial bioenergetics and function

    Esteras, N., Dinkova-Kostova, A. T. & Abramov, A. Y. May 2016 In : Biological Chemistry. 397, 5, p. 383-400 18 p.

    Research output: Contribution to journalArticle

  78. Spironolactone for people aged 70 or over with osteoarthritic knee pain: a proof-of-concept trial

    McMurdo, M. E. T., Sumukadas, D., Donnan, P. T., Cvoro, V., Rauchhaus, P., Argo, I., Waldie, H., Littleford, R., Struthers, A. D. & Witham, M. D. May 2016 In : Arthritis Care & Research. 68, 5, p. 716-721 6 p.

    Research output: Contribution to journalArticle

  79. Adherence to antiepileptic drugs in children with epilepsy in a Scottish population cohort

    Shetty, J., Greene, S. A., Mesalles-Naranjo, O. & Kirkpatrick, M. 22 Apr 2016 In : Developmental Medicine and Child Neurology. 58, 5, p. 469-474 6 p., 12942

    Research output: Contribution to journalArticle

  80. The essentiality of arachidonic acid in infant development

    Hadley, K. B., Ryan, A. S., Forsyth, S., Gautier, S. & Salem, N. 12 Apr 2016 In : Nutrients. 8, 4, 47 p., 216

    Research output: Contribution to journalArticle

  81. Synthesis, molecular modeling and NAD(P)H: quinone oxidoreductase 1 inducer activity of novel 2-phenylquinazolin-4-amine derivatives

    Ghorab, M. M., Alsaid, M. S., Higgins, M., Dinkova-Kostova, A. T., Shahat, A. A., Elghazawy, N. H. & Arafa, R. K. 7 Apr 2016 In : Journal of Enzyme Inhibition and Medicinal Chemistry. p. 1-7 7 p.

    Research output: Contribution to journalArticle

  82. Should studies of diabetes treatment stratification correct for baseline HbA1c?

    Jones, A. G., Lonergan, M., Henley, W. E., Pearson, E. R., Hattersley, A. T. & Shields, B. M. 6 Apr 2016 In : PLoS ONE. 11, 4, 14 p., e0152428

    Research output: Contribution to journalArticle

  83. The heparan sulfate sulfotransferase 3-OST3A (HS3ST3A) is a novel tumor regulator and a prognostic marker in breast cancer

    Mao, X., Gauche, C., Coughtrie, M. W. H., Bui, C., Gulberti, S., Merhi-Soussi, F., Ramalanjaona, N., Bertin-Jung, I., Diot, A., Dumas, D., De Freitas Caires, N., Thompson, A. M., Bourdon, J-C., Ouzzine, M. & Fournel-Gigleux, S. 4 Apr 2016 In : Oncogene. 13 p.

    Research output: Contribution to journalArticle

  84. Altered metabolic parameters in association with antipsychotic medication use in diabetes: A population based case-control study

    Wake, D. J., Broughton, P., Perera, S. M., MacIntyre, D. J. & Leese, G. P. 1 Apr 2016 In : Psychoneuroendocrinology. 66, p. 214-220 7 p.

    Research output: Contribution to journalArticle

  85. Making the invisible visible

    van Steensel, M. A. M. 1 Apr 2016 In : Seminars in Cell & Developmental Biology. 52, p. 58-65 8 p.

    Research output: Contribution to journalArticle

  86. Chemical constituents and NAD(P)H:Quinone oxidoreductase 1 (NQO1) inducer activity of Teucrium oliverianum Ging. ex Benth

    Shahat, A. A., Alsaid, M. S., Khan, J. A., Higgins, M. & Dinkova-Kostova, A. T. Apr 2016 In : Indian Journal of Traditional Knowledge. 15, 2, p. 232-236 5 p.

    Research output: Contribution to journalArticle

  87. During postnatal development endogenous neurosteroids influence GABA-ergic neurotransmission of mouse cortical neurons

    Brown, A. R., Mitchell, S., Peden, D. R., Herd, M. B., Seifi, M., Swinny, J. D., Belelli, D. & Lambert, J. Apr 2016 In : Neuropharmacology. 103, p. 163-173 11 p.

    Research output: Contribution to journalArticle

  88. Effects of adding Tiotropium or Aclidinium as triple therapy using impulse oscillometry in COPD

    Manoharan, A., Morrison, A. E. & Lipworth, B. Apr 2016 In : Lung. 194, 2, p. 259-266 8 p.

    Research output: Contribution to journalArticle

  89. Efficacy of the ulnar-basilic arteriovenous fistula for hemodialysis: a systematic review

    Al Shakarchi, J., Khawaja, A., Cassidy, D., Houston, J. G. & Inston, N. Apr 2016 In : Annals of Vascular Surgery. 32, p. 1-4 4 p.

    Research output: Contribution to journalArticle

  90. Feasibility and acceptability of TRANSFoRm to improve clinical trial recruitment in primary care

    Mastellos, N., Bliźniuk, G., Czopnik, D., McGilchrist, M., Misiaszek, A., Bródka, P., Curcin, V., Car, J., Delaney, B. C. & Andreasson, A. Apr 2016 In : Family Practice. 33, 2, p. 186-191 6 p., cmv102

    Research output: Contribution to journalArticle

  91. How does sex influence multimorbidity? Secondary analysis of a large nationally representative dataset

    Agur, K., McLean, G., Hunt, K., Guthrie, B. & Mercer, S. W. Apr 2016 In : International Journal of Environmental Research and Public Health. 13, 4, 12 p., 391

    Research output: Contribution to journalArticle

  92. Intravenous regional anaesthesia

    Checketts, M. R. Apr 2016 In : Anaesthesia and Intensive Care Medicine. 17, 4, p. 192-193 2 p.

    Research output: Contribution to journalArticle

  93. Is Gly16Arg β2 Receptor Polymorphism Related to Impulse Oscillometry in a Real-Life Asthma Clinic Setting?

    Jabbal, S., Manoharan, A., Lipworth, J., Anderson, W., Short, P. & Lipworth, B. Apr 2016 In : Lung. 194, 2, p. 267-271 5 p.

    Research output: Contribution to journalArticle

  94. Locally advanced basal cell carcinoma has a distinct methylation and transcriptomic profile

    Brinkhuizen, T., van Geel, M., Denil, S. L. I. J., De Meyer, T., Kelleners-Smeets, N. W. J., Lohuis, P. J. F. M., Hoebers, F. J. P., Winnepenninckx, V. J. L., van Steensel, M. A. M. & Mosterd, K. Apr 2016 In : Experimental Dermatology. 25, 4, p. 316-318 3 p.

    Research output: Contribution to journalLetter

  95. Post Hoc Analysis of Potential Predictors of Response to Atomoxetine for the Treatment of Adults with Attention-Deficit/Hyperactivity Disorder using an Integrated Database

    Bushe, C., Sobanski, E., Coghill, D., Berggren, L., De Bruyckere, K. & Leppämäki, S. Apr 2016 In : CNS Drugs. 30, 4, p. 317-334 18 p.

    Research output: Contribution to journalArticle

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