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  1. Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils

    Fan, Y., Howden, A. J. M., Sarhan, A. R., Lis, P., Ito, G., Martinez, T. N., Brockmann, K., Gasser, T., Alessi, D. R. & Sammler, E. 2 Jan 2018 In : Biochemical Journal. 475, 1, p. 23-44

    Research output: Contribution to journalArticle

  2. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Turcot, V. , Lu, Y. , Highland, H. M. , Schurmann, C. , Justice, A. E. , Fine, R. S. , Bradfield, J. P. , Esko, T. , Giri, A. , Graff, M. , Guo, X. , Hendricks, A. E. , Karaderi, T. , Lempradl, A. , Locke, A. E. , Mahajan, A. , Marouli, E. , Sivapalaratnam, S. , Young, K. L. , Alfred, T. & 380 others Feitosa, M. F., Masca, N. G. D., Manning, A. K., Medina-Gomez, C., Mudgal, P., Ng, M. C. Y., Reiner, A. P., Vedantam, S., Willems, S. M., Winkler, T. W., Abecasis, G., Aben, K. K., Alam, D. S., Alharthi, S. E., Allison, M., Amouyel, P., Asselbergs, F. W., Auer, P. L., Balkau, B., Bang, L. E., Barroso, I., Bastarache, L., Benn, M., Bergmann, S., Bielak, L. F., Blüher, M., Boehnke, M., Boeing, H., Boerwinkle, E., Böger, C. A., Bork-Jensen, J., Bots, M. L., Bottinger, E. P., Bowden, D. W., Brandslund, I., Breen, G., Brilliant, M. H., Broer, L., Brumat, M., Burt, A. A., Butterworth, A. S., Campbell, P. T., Cappellani, S., Carey, D. J., Catamo, E., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Chen, Y. D. I., Chowdhury, R., Christensen, C., Chu, A. Y., Cocca, M., Collins, F. S., Cook, J. P., Corley, J., Corominas Galbany, J., Cox, A. J., Crosslin, D. S., Cuellar-Partida, G., D'Eustacchio, A., Danesh, J., Davies, G., Bakker, P. I. W., Groot, M. C. H., Mutsert, R., Deary, I. J., Dedoussis, G., Demerath, E. W., Heijer, M., Hollander, A. I., Ruijter, H. M., Dennis, J. G., Denny, J. C., Angelantonio, E., Drenos, F., Du, M., Dubé, M. P., Dunning, A. M., Easton, D. F., Edwards, T. L., Ellinghaus, D., Ellinor, P. T., Elliott, P., Evangelou, E., Farmaki, A. E., Farooqi, I. S., Faul, J. D., Fauser, S., Feng, S., Ferrannini, E., Ferrieres, J., Florez, J. C., Ford, I., Fornage, M., Franco, O. H., Franke, A., Franks, P. W., Friedrich, N., Frikke-Schmidt, R., Galesloot, T. E., Gan, W., Gandin, I., Gasparini, P., Gibson, J., Giedraitis, V., Gjesing, A. P., Gordon-Larsen, P., Gorski, M., Grabe, H. J., Grant, S. F. A., Grarup, N., Griffiths, H. L., Grove, M. L., Gudnason, V., Gustafsson, S., Haessler, J., Hakonarson, H., Hammerschlag, A. R., Hansen, T., Harris, K. M., Harris, T. B., Hattersley, A. T., Have, C. T., Hayward, C., He, L., Heard-Costa, N. L., Heath, A. C., Heid, I. M., Helgeland, Ø., Hernesniemi, J., Hewitt, A. W., Holmen, O. L., Hovingh, G. K., Howson, J. M. M., Hu, Y., Huang, P. L., Huffman, J. E., Ikram, M. A., Ingelsson, E., Jackson, A. U., Jansson, J. H., Jarvik, G. P., Jensen, G. B., Jia, Y., Johansson, S., Jørgensen, M. E., Jørgensen, T., Jukema, J. W., Kahali, B., Kahn, R. S., Kähönen, M., Kamstrup, P. R., Kanoni, S., Kaprio, J., Karaleftheri, M., Kardia, S. L. R., Karpe, F., Kathiresan, S., Kee, F., Kiemeney, L. A., Kim, E., Kitajima, H., Komulainen, P., Kooner, J. S., Kooperberg, C., Korhonen, T., Kovacs, P., Kuivaniemi, H., Kutalik, Z., Kuulasmaa, K., Kuusisto, J., Laakso, M., Lakka, T. A., Lamparter, D., Lange, E. M., Lange, L. A., Langenberg, C., Larson, E. B., Lee, N. R., Lehtimäki, T., Lewis, C. E., Li, H., Li, J., Li-Gao, R., Lin, H., Lin, K. H., Lin, L. A., Lin, X., Lind, L., Lindström, J., Linneberg, A., Liu, C. T., Liu, D. J., Liu, Y., Lo, K. S., Lophatananon, A., Lotery, A. J., Loukola, A., Luan, J. A., Lubitz, S. A., Lyytikäinen, L. P., Männistö, S., Marenne, G., Mazul, A. L., McCarthy, M. I., McKean-Cowdin, R., Medland, S. E., Meidtner, K., Milani, L., Mistry, V., Mitchell, P., Mohlke, K. L., Moilanen, L., Moitry, M., Montgomery, G. W., Mook-Kanamori, D. O., Moore, C., Mori, T. A., Morris, A. P., Morris, A. P., Müller-Nurasyid, M., Munroe, P. B., Nalls, M. A., Narisu, N., Nelson, C. P., Neville, M., Nielsen, S. F., Nikus, K., Njølstad, P. R., Nordestgaard, B. G., Nyholt, D. R., O'Connel, J. R., O'Donoghue, M. L., Olde Loohuis, L. M., Ophoff, R. A., Owen, K. R., Packard, C. J., Padmanabhan, S., Palmer, C. N. A., Palmer, N. D., Pasterkamp, G., Patel, A. P., Pattie, A., Pedersen, O., Peissig, P. L., Peloso, G. M., Pennell, C. E., Perola, M., Perry, J. A., Perry, J. R. B., Pers, T. H., Person, T. N., Peters, A., Petersen, E. R. B., Peyser, P. A., Pirie, A., Polasek, O., Polderman, T. J., Puolijoki, H., Raitakari, O. T., Rasheed, A., Rauramaa, R., Reilly, D. F., Renström, F., Rheinberger, M., Ridker, P. M., Rioux, J. D., Rivas, M. A., Roberts, D. J., Robertson, N. R., Robino, A., Rolandsson, O., Rudan, I., Ruth, K. S., Saleheen, D., Salomaa, V., Samani, N. J., Sapkota, Y., Sattar, N., Schoen, R. E., Schreiner, P. J., Schulze, M. B., Scott, R. A., Segura-Lepe, M. P., Shah, S. H., Sheu, W. H. H., Sim, X., Slater, A. J., Small, K. S., Smith, A. V., Southam, L., Spector, T. D., Speliotes, E. K., Starr, J. M., Stefansson, K., Steinthorsdottir, V., Stirrups, K. E., Strauch, K., Stringham, H. M., Stumvoll, M., Sun, L., Surendran, P., Swift, A. J., Tada, H., Tansey, K. E., Tardif, J. C., Taylor, K. D., Teumer, A., Thompson, D. J., Thorleifsson, G., Thorsteinsdottir, U., Thuesen, B. H., Tönjes, A., Tromp, G., Trompet, S., Tsafantakis, E., Tuomilehto, J., Tybjaerg-Hansen, A., Tyrer, J. P., Uher, R., Uitterlinden, A. G., Uusitupa, M., Laan, S. W., Duijn, C. M., Leeuwen, N., Van Setten, J., Vanhala, M., Varbo, A., Varga, T. V., Varma, R., Velez Edwards, D. R., Vermeulen, S. H., Veronesi, G., Vestergaard, H., Vitart, V., Vogt, T. F., Völker, U., Vuckovic, D., Wagenknecht, L. E., Walker, M., Wallentin, L., Wang, F., Wang, C. A., Wang, S., Wang, Y., Ware, E. B., Wareham, N. J., Warren, H. R., Waterworth, D. M., Wessel, J., White, H. D., Willer, C. J., Wilson, J. G., Witte, D. R., Wood, A. R., Wu, Y., Yaghootkar, H., Yao, J., Yao, P., Yerges-Armstrong, L. M., Young, R., Zeggini, E., Zhan, X., Zhang, W., Zhao, J. H., Zhao, W., Zhou, W., Zondervan, K. T., Rotter, J. I., Pospisilik, J. A., Rivadeneira, F., Borecki, I. B., Deloukas, P., Frayling, T. M., Lettre, G., North, K. E., Lindgren, C. M., Hirschhorn, J. N. & Loos, R. J. F. 1 Jan 2018 In : Nature Genetics. 50, 1, p. 26-35 10 p.

    Research output: Contribution to journalArticle

  3. The effect of perindopril on postural instability in older people with a history of falls-a randomised controlled trial

    Sumukadas, D., Price, R., McMurdo, M. E. T., Rauchhaus, P., Struthers, A., McSwiggan, S., Arnold, G., Abboud, R. & Witham, M. 1 Jan 2018 In : Age and Ageing. 47, 1, p. 75-81 7 p.

    Research output: Contribution to journalArticle

  4. Differential Distribution of Retinal Ca2+/Calmodulin-Dependent Kinase II (CaMKII) Isoforms Indicates CaMKII-β and -δ as Specific Elements of Electrical Synapses Made of Connexin36 (Cx36)

    Tetenborg, S., Yadav, S. C., Hormuzdi, S. G., Monyer, H., Janssen-Bienhold, U. & Dedek, K. 19 Dec 2017 In : Frontiers in Molecular Neuroscience. 10, 15 p., 425

    Research output: Contribution to journalArticle

  5. Balancing training and outcomes in total knee replacement: A ten-year review

    Faulkner, A., Reidy, M. J., Davies, P. S. E., Wang, W., Buddhadev, N., Johnston, L. & Clift, B. 13 Dec 2017 In : Surgeon. 5 p.

    Research output: Contribution to journalArticle

  6. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein-coupled receptors

    Alexander, S. P. H., Christopoulos, A., Davenport, A. P., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174, Suppl. 1, p. S17-S129 113 p.

    Research output: Contribution to journalArticle

  7. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Voltage-gated ion channels

    Alexander, S. P. H., Striessnig, J., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S160-S194 35 p.

    Research output: Contribution to journalArticle

  8. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Other ion channels

    Alexander, S. P. H., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S195-S207 13 p.

    Research output: Contribution to journalArticle

  9. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Ligand-gated ion channels

    Alexander, S. P. H., Peters, J. A., Kelly, E., Marrion, N. V., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S130-S159 30 p.

    Research output: Contribution to journalArticle

  10. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Catalytic receptors

    Alexander, S. P. H., Fabbro, D., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S225-S271 47 p.

    Research output: Contribution to journalArticle

  11. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview

    Alexander, S. P. H., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Buneman, O. P., Cidlowski, J. A., Christopoulos, A., Davenport, A. P., Fabbro, D., Spedding, M., Striessnig, J., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S1-S16 16 p.

    Research output: Contribution to journalArticle

  12. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes

    Alexander, S. P. H., Fabbro, D., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S272-S359 88 p.

    Research output: Contribution to journalArticle

  13. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Nuclear hormone receptors

    Alexander, S. P. H., Cidlowski, J. A., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S208-S224 17 p.

    Research output: Contribution to journalArticle

  14. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters

    Alexander, S. P. H., Kelly, E., Marrion, N. V., Peters, J. A., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators Dec 2017 In : British Journal of Pharmacology. 174 , Suppl. 1, p. S360-S446 87 p.

    Research output: Contribution to journalArticle

  15. Editorial: Role of protein-protein interactions in metabolism: Genetics, structure, function

    Pandey, A. V., Henderson, C. J., Ishii, Y., Kranendonk, M., Backes, W. L. & Zanger, U. M. 27 Nov 2017 In : Frontiers in Pharmacology. 8, p. 1-3 3 p., 881

    Research output: Contribution to journalEditorial

  16. Genetic mannose binding lectin deficiency is associated with airway microbiota diversity and reduced exacerbation frequency in COPD

    Dicker, A. J., Crichton, M. L., Cassidy, A. J., Brady, G., Hapca, A., Tavendale, R., Einarsson, G. G., Furrie, E., Elborn, J. S., Schembri, S., Marshall, S. E., Palmer, C. N. A. & Chalmers, J. D. 3 Nov 2017 In : Thorax.

    Research output: Contribution to journalArticle

  17. Development of a therapeutic capsule endoscope for treatment in the gastrointestinal tract: Bench testing to translational trial

    Stewart, F. R., Newton, I. P., Nathke, I., Huang, Z., Cox, B. F. & Cochran, S. 2 Nov 2017 2017 IEEE International Ultrasonics Symposium (IUS). United States: IEEE, p. 1-4 4 p. 8091791. (IEEE International Ultrasonics Symposium)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  18. A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway

    Sartelli, M. , Kluger, Y. , Ansaloni, L. , Carlet, J. , Brink, A. J. , Hardcastle, T. C. , Khanna, A. , Chicom-Mefire, A. , Rodríguez-Baño, J. , Nathwani, D. , Mendelson, M. , Watkins, R. R. , Pulcini, C. , Beović, B. , May, A. K. , Itani, K. M. F. , Mazuski, J. E. , Fry, D. E. , Coccolini, F. , Rasxa, K. & 218 others Montravers, P., Eckmann, C., Abbo, L. M., Abubakar, S., Abu-Zidan, F. M., Adesunkanmi, A. K., Al-Hasan, M. N., Althani, A. A., Ticas, J. E. A., Ansari, S., Ansumana, R., Da Silva, A. R. A., Augustin, G., Bala, M., Balogh, Z. J., Baraket, O., Bassetti, M., Bellanova, G., Beltran, M. A., Ben-Ishay, O., Biffl, W. L., Boermeester, M. A., Brecher, S. M., Bueno, J., Cainzos, M. A., Cairns, K. A., Camacho-Ortiz, A., Ceresoli, M., Chandy, S. J., Cherry-Bukowiec, J. R., Cirocchi, R., Colak, E., Corcione, A., Cornely, O. A., Cortese, F., Cui, Y., Curcio, D., Damaskos, D., Dasx, K., Delibegovic, S., Demetrashvili, Z., De Simone, B., De Souza, H. P., De Waele, J., Dhingra, S., Diaz, J. J., Di Carlo, I., Di Marzo, F., Di Saverio, S., Dogjani, A., Dorj, G., Dortet, L., Duane, T. M., Dupont, H., Egiev, V. N., Eid, H. O., Elmangory, M., El-Sayed Marei, H., Enani, M. A., Escandón-Vargas, K., Faro, M. P., Ferrada, P., Foghetti, D., Foianini, E., Fraga, G. P., Frattima, S., Gandhi, C., Gattuso, G., Giamarellou, E., Ghnnam, W., Gkiokas, G., Girardis, M., Goff, D. A., Gomes, C. A., Gomi, H., Gronerth, R. I. G., Guirao, X., Guzman-Blanco, M., Haque, M., Hecker, A., Hell, M., Herzog, T., Hicks, L., Kafka-Ritsch, R., Kao, L. S., Kanj, S. S., Kaplan, L. J., Kapoor, G., Karamarkovic, A., Kashuk, J., Kenig, J., Khamis, F., Khokha, V., Kiguba, R., Kirkpatrick, A. W., Kørner, H., Koike, K., Kok, K. Y. Y., Kon, K., Kong, V., Inaba, K., Ioannidis, O., Isik, A., Iskandar, K., Labbate, M., Labricciosa, F. M., Lagrou, K., Lagunes, L., Latifi, R., Lasithiotakis, K., Laxminarayan, R., Lee, J. G., Leone, M., Leppäniemi, A., Li, Y., Liang, S. Y., Liau, K. H., Litvin, A., Loho, T., Lowman, W., Machain, G. M., Maier, R. V., Manzano-Nunez, R., Marinis, A., Marmorale, C., Martin-Loeches, I., Marwah, S., Maseda, E., McFarlane, M., De Melo, R. B., Melotti, M. R., Memish, Z., Mertz, D., Mesina, C., Menichetti, F., Mishra, S. K., Montori, G., Moore, E. E., Moore, F. A., Naidoo, N., Napolitano, L., Negoi, I., Nicolau, D. P., Nikolopoulos, I., Nord, C. E., Ofori-Asenso, R., Olaoye, I., Omari, A. H., Ordoñez, C. A., Ouadii, M., Ouedraogo, A. S., Pagani, L., Paiva, J. A., Parreira, J. G., Pata, F., Pereira, J., Rocha-Pereira, N., Petrosillo, N., Picetti, E., Pintar, T., Ponce-De-Leon, A., Popovski, Z., Poulakou, G., Preller, J., Guerrero, A. P., Pupelis, G., Quiodettis, M., Rawson, T. M., Reichert, M., Reinhart, K., Rems, M., Rello, J., Rizoli, S., Roberts, J., Rubio-Perez, I., Ruppé, E., Sakakushev, B., Sall, I., Kafil, H. S., Sanders, J., Sato, N., Sawyer, R. G., Scalea, T., Scibé, R., Scudeller, L., Lohse, H. S., Sganga, G., Shafiq, N., Shah, J. N., Spigaglia, P., Suroowan, S., Tsioutis, C., Sifri, C. D., Siribumrungwong, B., Sugrue, M., Talving, P., Tan, B. K., Tarasconi, A., Tascini, C., Tilsed, J., Timsit, J. F., Tumbarello, M., Trung, N. T., Ulrych, J., Uranues, S., Velmahos, G., Vereczkei, A. G., Viale, P., Estape, J. V., Viscoli, C., Wagenlehner, F., Wright, B. J., Xiao, Y., Yuan, K. C., Zachariah, S. K., Zahar, J. R., Mergulhão, P. & Catena, F. 1 Nov 2017 In : Surgical Infections. 18, 8, p. 846-853 8 p.

    Research output: Contribution to journalArticle

  19. Cruciate Retaining compared with Posterior Stabilised Nexgen total knee arthroplasty: results at 10 years in a matched cohort

    Mayne, A. I. W., Harshavardhan, H. P., Johnston, L. R., Wang, W. & Jariwala, A. Nov 2017 In : Annals of the Royal College of Surgeons of England. 99, 8, p. 602-606 5 p.

    Research output: Contribution to journalArticle

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