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  1. Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

    Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J. 20 Nov 2016 New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January, p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  2. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

    Cameron, A. R., Morrison, V., Levin, D., Mohan, M., Forteath, C., Beall, C., McNeilly, A. D., Balfour, D. J. K., Savinko, T., Wong, A. K. F., Viollet, B., Sakamoto, K., Fagerholm, S. C., Foretz, M., Lang, C. C. & Rena, G. 19 Aug 2016 In : Circulation Research. 119, 5, p. 652-665 14 p.

    Research output: Contribution to journalArticle

  3. Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

    Daniels, M. J. D. , Rivers-Auty, J. , Schilling, T. , Spencer, N. G. , Watremez, W. , Fasolino, V. , Booth, S. J. , White, C. S. , Baldwin, A. G. , Freeman, S. , Wong, R. , Latta, C. , Yu, S. , Jackson, J. , Fischer, N. , Koziel, V. , Pillot, T. , Bagnall, J. , Allan, S. M. & 6 others Paszek, P., Galea, J., Harte, M. K., Eder, C., Lawrence, C. B. & Brough, D. 11 Aug 2016 In : Nature Communications. 7, 10 p., 12504

    Research output: Contribution to journalArticle

  4. The genetic architecture of type 2 diabetes

    Morris, A. D. & 300 others Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F., Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B-J., Kim, Y., Kim, Y. J., Kwon, M-S., Lee, J., Lee, S., Lin, K-H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B-G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S-H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C-Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C-C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., van der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S-T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., Hrabé de Angelis, M., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A-C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J-Y., Park, T., Donnelly, P., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M., Altshuler, D. & McCarthy, M. I. 4 Aug 2016 In : Nature. 536, p. 41-47 29 p., 18642

    Research output: Contribution to journalArticle

  5. Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells

    Leitch, C. S., Natafji, E., Yu, C., Abdul-Ghaffar, S., Madarasingha, N., Venables, Z. C., Chu, R., Fitch, P. M., Muinonen-Martin, A. J., Campbell, L. E., McLean, W. H. I., Schwarze, J., Howie, S. E. M. & Weller, R. B. Aug 2016 In : Journal of Allergy and Clinical Immunology. 138, 2, p. 482-490.e7 16 p.

    Research output: Contribution to journalArticle

  6. Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug

    Cameron, A., Logie, L., Patel, K., Bacon, S., Forteath, C., Harthill, J., Roberts, A., Sutherland, C., Stewart, D., Viollet, B., Sakamoto, K., McDougall, G., Foretz, M. & Rena, G. Aug 2016 In : Biochimica et Biophysica Acta. Molecular Basis of Disease. 1862, 8, p. 1412-1422 11 p.

    Research output: Contribution to journalArticle

  7. Rhodiola rosea L.: from golden root to green cell factories

    Marchev, A. S., Dinkova-Kostova, A. T., György, Z., Mirmazloum, I., Aneva, I. Y. & Georgiev, M. I. Aug 2016 In : Phytochemistry Reviews. 15, 4, p. 515-536 22 p.

    Research output: Contribution to journalArticle

  8. Trends in type 2 diabetes incidence and mortality in Scotland between 2004 and 2013

    Read, S. H., Kerssens, J. J., McAllister, D. A., Colhoun, H. M., Fischbacher, C. M., Lindsay, R. S., McCrimmon, R. J., McKnight, J. A., Petrie, J. R., Sattar, N., Wild, S. H. & On behalf of the Scottish Diabetes Research Network Epidemiology Group 28 Jul 2016 In : Diabetologia. 8 p.

    Research output: Contribution to journalArticle

  9. A hydraulically driven colonoscope

    Coleman, S. A., Tapia Siles, S. C., Pakleppa, M., Vorstius, J. B., Keatch, R. P., Tang, B. & Cuschieri, A. 22 Jul 2016 In : Surgical Endoscopy. p. 1-10 11 p.

    Research output: Contribution to journalArticle

  10. SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models

    Naidu, S. D. , Dinkova-Kostova, A. T. & 22 others Quinti, L., Casale, M., Moniot, S., Pais, T. F., Van Kanegan, M. J., Kaltenbach, L. S., Pallos, J., Lim, R. G., Runne, H., Meisel, L., Rauf, N. A., Leyfer, D., Maxwell, M. M., Saiah, E., Landers, J. E., Luthi-Carter, R., Abagyan, R., Steegborn, C., Marsh, J. L., Lo, D. C., Thompson, L. M. & Kazantsev, A. G. 21 Jul 2016 In : Cell Chemical Biology. 23, 7, p. 849-861 13 p.

    Research output: Contribution to journalArticle

  11. Mutations in the mevalonate pathway genes in Chinese patients with porokeratosis

    Li, M., Li, Z., Wang, J., Ni, C., Sun, Z., Wilson, N. J., Zhang, J., Chen, F., Li, X., Du, X., Yu, H., Zhang, L., Smith, F. J. D., Zhang, G. & Yao, Z. 16 Jul 2016 In : Journal of the European Academy of Dermatology and Venereology. 6 p.

    Research output: Contribution to journalArticle

  12. Feedback in surgical education

    El Boghdady, M. & Alijani, A. 15 Jul 2016 In : Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 6 p.

    Research output: Contribution to journalArticle

  13. Laparoscopic assisted colonoscopy: results and follow up endoscopic success

    Quyn, A. J., Vujovic, Z., Ziyaie, D., Steele, R. J. C. & Campbell, K. L. 15 Jul 2016 In : Colorectal Disease.

    Research output: Contribution to journalArticle

  14. Expression of P53 and isoforms in bening and malignant lesions of the head and neck

    Trovato, M., Ruggeri, R. M., Guzzo, E., Certo, R., Alibrandi, A., Scifo, S., Scardigno, M., Vitarelli, E., Arena, G., Gambadoro, O., Catalano, N., Bourdon, J. C., Galletti, B., Galletti, F. & Cavallari, V. 14 Jul 2016 In : Histology and Histopathology. 11802

    Research output: Contribution to journalArticle

  15. Safety, complications and patients' acceptance of Mohs micrographic surgery (MMS) under local anaesthesia - results from the UK MAPS (Mohs Acceptance and Patient Safety) Collaboration Group

    Hussain, W., Affleck, A., Al-Niaimi, F., Cooper, A., Craythorne, E., Fleming, C., Ghura, V., Langtry, J., Lawrence, C., Loghdey, S., Naysmith, L., Oliphant, T., Rahim, R., Rice, S., Sivaramkrishan, M., Stables, G., Varma, S. & Mallipeddi, R. 5 Jul 2016 In : British Journal of Dermatology.

    Research output: Contribution to journalLetter

  16. An empirical comparison of joint and stratified frameworks for studying G x E interactions: systolic blood pressure and smoking in the CHARGE gene-lifestyle interactions working group

    Smith, B. H. & 57 others Sung, Y. J., Winkler, T. W., Manning, A. K., Aschard, H., Gudnason, V., Harris, T. B., Smith, A. V., Boerwinkle, E., Brown, M. R., Morrison, A. C., Fornage, M., Lin, L. A., Richard, M., Bartz, T. M., Psaty, B. M., Hayward, C., Polasek, O., Marten, J., Rudan, I., Feitosa, M. F., Kraja, A. T., Province, M. A., Deng, X., Fisher, V. A., Zhou, Y., Bielak, L. F., Smith, J., Huffman, J. E., Padmanabhan, S., Ding, J., Liu, Y., Lohman, K., Bouchard, C., Rankinen, T., Rice, T. K., Arnett, D., Schwander, K., Guo, X., Palmas, W., Rotter, J. I., Alfred, T., Bottinger, E. P., Loos, R. J. F., Amin, N., Franco, O. H., van Duijn, C. M., Vojinovic, D., Chasman, D. I., Ridker, P. M., Rose, L. M., Kardia, S., Zhu, X., Rice, K., Borecki, I. B., Rao, D. C., Gauderman, W. J. & Cupples, L. A. Jul 2016 In : Genetic Epidemiology. 40, 5, p. 404-415 12 p., 21978

    Research output: Contribution to journalArticle

  17. Liver retraction system by C3-muco-adhesive polymer films for laparoscopic surgery

    Aldeghaither, S., Tang, B., Alijani, A., McLean, D., Wright, E., Wang, Z., Tait, I. & Cuschieri, A. Jul 2016 In : Surgical Endoscopy. 30, 7, p. 2834-2839 6 p.

    Research output: Contribution to journalArticle

  18. Transcutaneous Electrical Nerve Stimulation improves walking performance in patients with intermittent claudication

    Seenan, C., McSwiggan, S., Roche, P. A., Tan, C-W., Mercer, T. & Belch, J. J. F. Jul 2016 In : European Journal of Cardiovascular Nursing. 31, 4, p. 323-330 8 p.

    Research output: Contribution to journalArticle

  19. Respiratory effect of beta-blocker eye drops in asthma: population-based study and meta-analysis of clinical trials

    Morales, D. R., Dreischulte, T., Lipworth, B. J., Donnan, P. T., Jackson, C. & Guthrie, B. Sep 2016 In : British Journal of Clinical Pharmacology. 82, 3, p. 814-822 9 p.

    Research output: Contribution to journalArticle

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