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  1. Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

    Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J. 20 Nov 2016 New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January, p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  2. Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

    Khan, F. , Belch, J. & 25 others Gonçalves, I., Edsfeldt, A., Colhoun, H. M., Shore, A. C., Palombo, C., Natali, A., Fredrikson, G. N., Björkbacka, H., Wigren, M., Bengtsson, E., Östling, G., Aizawa, K., Casanova, F., Persson, M., Gooding, K., Gates, P., Looker, H. C., Adams, F., Pinnola, S., Venturi, E., Kozakova, M., Gan, L-M., Schnecke, V., Nilsson, J. & on behalf of the SUMMIT consortium 5 Sep 2016 In : BMC Cardiovascular Disorders. 16, p. 1-10 10 p., 171

    Research output: Contribution to journalArticle

  3. Skin microbiome prior to development of atopic dermatitis: early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year

    Kennedy, E. A., Connolly, J., O.'B. Hourihane, J., Fallon, P. G., McLean, W. H. I., Murray, D., Jo, J-H., Segre, J. A., Kong, H. H. & Irvine, A. D. 5 Sep 2016 In : Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalArticle

  4. The effect of dietary intervention on the metabolic and behavioural impairments generated by short term high fat feeding in the rat

    McNeilly, A. D., Gao, A., Hill, A. Y., Gomersall, T., Balfour, D. J. K., Sutherland, C. & Stewart, C. A. 1 Dec 2016 In : Physiology & Behavior. 167, p. 100-109 10 p.

    Research output: Contribution to journalArticle

  5. Childhood obesity in relation to poor asthma control and exacerbation: a meta-analysis

    Ahmadizar, F., Vijverberg, S. J. H., Arets, H. G. M., de Boer, A., Lang, J. E., Kattan, M., Palmer, C. N. A., Mukhopadhyay, S., Turner, S. & Maitland-van der Zee, A. H. 1 Sep 2016 In : European Respiratory Journal.

    Research output: Contribution to journalArticle

  6. Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

    Postmus, I. , Warren, H. R. , Trompet, S. , Arsenault, B. J. , Avery, C. L. , Bis, J. C. , Chasman, D. I. , de Keyser, C. E. , Deshmukh, H. A. , Evans, D. S. , Feng, Q. , Li, X. , Smit, R. A. J. , Smith, A. V. , Sun, F. , Taylor, K. D. , Arnold, A. M. , Barnes, M. R. , Barratt, B. J. & 69 others Betteridge, J., Boekholdt, S. M., Boerwinkle, E., Buckley, B. M., Chen, Y-D. I., de Craen, A. J. M., Cummings, S. R., Denny, J. C., Dubé, M. P., Durrington, P. N., Eiriksdottir, G., Ford, I., Guo, X., Harris, T. B., Heckbert, S. R., Hofman, A., Hovingh, G. K., Kastelein, J. J. P., Launer, L. J., Liu, C-T., Liu, Y., Lumley, T., McKeigue, P. M., Munroe, P. B., Neil, A., Nickerson, D. A., Nyberg, F., O'Brien, E., O'Donnell, C. J., Post, W., Poulter, N., Vasan, R. S., Rice, K., Rich, S. S., Rivadeneira, F., Sattar, N., Sever, P., Shaw-Hawkins, S., Shields, D. C., Slagboom, P. E., Smith, N. L., Smith, J. D., Sotoodehnia, N., Stanton, A., Stott, D. J., Stricker, B. H., Stürmer, T., Uitterlinden, A. G., Wei, W-Q., Westendorp, R. G. J., Whitsel, E. A., Wiggins, K. L., Wilke, R. A., Ballantyne, C. M., Colhoun, H. M., Cupples, L. A., Franco, O. H., Gudnason, V., Hitman, G., Palmer, C. N. A., Psaty, B. M., Ridker, P. M., Stafford, J. M., Stein, C. M., Tardif, J-C., Caulfield, M. J., Jukema, J. W., Rotter, J. I. & Krauss, R. M. 1 Sep 2016 In : Journal of Medical Genetics. 11 p.

    Research output: Contribution to journalArticle

  7. The effect of a performance based intra-procedural checklist on a simulated emergency laparoscopic task in novice surgeons

    El Boghdady, M., Tang, B. & Alijani, A. 1 Sep 2016 In : Surgical Endoscopy. 5 p.

    Research output: Contribution to journalArticle

  8. 30-day mortality after systemic anticancer treatment for breast and lung cancer in England: a population-based, observational study

    Wallington, M., Saxon, E. B., Bomb, M., Smittenaar, R., Wickenden, M., McPhail, S., Rashbass, J., Chao, D., Dewar, J., Talbot, D., Peake, M., Perren, T., Wilson, C. & Dodwell, D. Sep 2016 In : Lancet Oncology. 17, 9, p. 1203-1216 14 p.

    Research output: Contribution to journalArticle

  9. MEK is a therapeutic and chemopreventative target in squamous cell carcinoma

    Adelmann, C. H., Truong, K. A., Liang, R. J., Bansal, V., Gandee, L., Saporito, R., Lee, W., Du, L., Nicholas, C., Napoli, M., Mino, B., South, A. P., Proby, C. M., Leigh, I. M., Coarfa, C., Flores, E. R. & Tsai, K. Y. Sep 2016 In : Journal of Investigative Dermatology. 136, 9, p. 1920-1924 5 p.

    Research output: Contribution to journalLetter

  10. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

    Cameron, A. R., Morrison, V., Levin, D., Mohan, M., Forteath, C., Beall, C., McNeilly, A. D., Balfour, D. J. K., Savinko, T., Wong, A. K. F., Viollet, B., Sakamoto, K., Fagerholm, S. C., Foretz, M., Lang, C. C. & Rena, G. 19 Aug 2016 In : Circulation Research. 119, 5, p. 652-665 14 p.

    Research output: Contribution to journalArticle

  11. Mutations in the mevalonate pathway genes in Chinese patients with porokeratosis

    Li, M., Li, Z., Wang, J., Ni, C., Sun, Z., Wilson, N. J., Zhang, J., Chen, F., Li, X., Du, X., Yu, H., Zhang, L., Smith, F. J. D., Zhang, G. & Yao, Z. 19 Aug 2016 In : Journal of the European Academy of Dermatology and Venereology. 30, 9, p. 1512-1517 6 p.

    Research output: Contribution to journalArticle

  12. tRNA methyltransferase homologue gene TRMT10A mutation in young adult-onset diabetes with intellectual disability, microcephaly and epilepsy

    Yew, T. W., McCreight, L., Colclough, K., Ellard, S. & Pearson, E. R. 17 Aug 2016 In : Diabetic Medicine. 33, 9, p. e21-e25 5 p.

    Research output: Contribution to journalArticle

  13. Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

    Daniels, M. J. D. , Rivers-Auty, J. , Schilling, T. , Spencer, N. G. , Watremez, W. , Fasolino, V. , Booth, S. J. , White, C. S. , Baldwin, A. G. , Freeman, S. , Wong, R. , Latta, C. , Yu, S. , Jackson, J. , Fischer, N. , Koziel, V. , Pillot, T. , Bagnall, J. , Allan, S. M. & 6 others Paszek, P., Galea, J., Harte, M. K., Eder, C., Lawrence, C. B. & Brough, D. 11 Aug 2016 In : Nature Communications. 7, p. 1-10 10 p., 12504

    Research output: Contribution to journalArticle

  14. Respiratory effect of beta-blocker eye drops in asthma: population-based study and meta-analysis of clinical trials

    Morales, D. R., Dreischulte, T., Lipworth, B. J., Donnan, P. T., Jackson, C. & Guthrie, B. 8 Aug 2016 In : British Journal of Clinical Pharmacology. 82, 3, p. 814-822 9 p.

    Research output: Contribution to journalArticle

  15. The genetic architecture of type 2 diabetes

    Morris, A. D. & 300 others Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F., Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B-J., Kim, Y., Kim, Y. J., Kwon, M-S., Lee, J., Lee, S., Lin, K-H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B-G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S-H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C-Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C-C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., van der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S-T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., Hrabé de Angelis, M., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A-C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J-Y., Park, T., Donnelly, P., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M., Altshuler, D. & McCarthy, M. I. 4 Aug 2016 In : Nature. 536, p. 41-47 29 p., 18642

    Research output: Contribution to journalArticle

  16. Arterio-venous differences in cord levels of catecholamines, glucose, lactate and blood gases

    Koh, D. K. M., Hume, R., Eisenhofer, G., Watson, J. & Williams, F. L. R. 1 Aug 2016 In : Journal of Perinatal Medicine. 44, 6, p. 695-704 10 p.

    Research output: Contribution to journalArticle

  17. Reports of Perceived Adverse Events of Stimulant Medication on Cognition, Motivation, and Mood: Qualitative Investigation and the Generation of Items for the Medication and Cognition Rating Scale

    Kovshoff, H., Banaschewski, T., Buitelaar, J. K., Carucci, S., Coghill, D., Danckaerts, M., Dittmann, R. W., Falissard, B., Grimshaw, D. G., Hollis, C., Inglis, S., Konrad, K., Liddle, E., McCarthy, S., Nagy, P., Thompson, M., Wong, I. C. K., Zuddas, A. & Sonuga-Barke, E. J. S. 1 Aug 2016 In : Journal of Child and Adolescent Psychopharmacology. 26, 6, p. 537-547 11 p.

    Research output: Contribution to journalArticle

  18. Acute risk factors in fatal opioid overdoses as a result of hypoxia and cardiotoxicity. A systematic review and critical appraisal

    Baldacchino, A., Tolomeo, S., Khan, F., Humphris, G. & Carrà, G. Aug 2016 In : Heroin Addiction and Related Clinical Problems. 18, 4, p. 33-42 10 p.

    Research output: Contribution to journalReview article

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