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  1. Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

    Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J. 20 Nov 2016 New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January, p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  2. Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer

    Schmid, P. , Pinder, S. E. , Wheatley, D. , Macaskill, J. , Zammit, C. , Hu, J. , Price, R. , Bundred, N. , Hadad, S. , Shia, A. , Sarker, S. J. , Lim, L. , Gazinska, P. , Woodman, N. , Korbie, D. , Trau, M. , Mainwaring, P. , Gendreau, S. , Lackner, M. R. & 7 others Derynck, M., Wilson, T. R., Butler, H., Earl, G., Parker, P., Purushotham, A. & Thompson, A. 10 Jun 2016 In : Journal of Clinical Oncology. 34, 17, p. 1987-1994 8 p.

    Research output: Contribution to journalArticle

  3. Analysis of physical pore space characteristics of two pyrolytic biochars and potential as microhabitat

    Schnee, L. S., Knauth, S., Hapca, S., Otten, W. & Eickhorst, T. 2 Jun 2016 In : Plant and Soil. p. 1-12 12 p.

    Research output: Contribution to journalArticle

  4. Medical humanities: A closer look at learning

    Patterson, A., Sharek, D., Hennessy, M., Phillips, M. & Schofield, S. 1 Jun 2016 In : Medical Humanities. 42, 2, p. 115-120 6 p.

    Research output: Contribution to journalArticle

  5. How well do contoured superior midshaft clavicle plates fit the clavicle?: A cadaveric study

    Malhas, A. M., Skarparis, Y. G., Sripada, S., Soames, R. W. & Jariwala, A. C. Jun 2016 In : Journal of Shoulder and Elbow Surgery. 25, 6, p. 954-959 6 p.

    Research output: Contribution to journalArticle

  6. Exosome-mediated transfer from the tumor microenvironment increases TGFβ signaling in squamous cell carcinoma

    Languino, L. R., Singh, A., Prisco, M., Inman, G. J., Luginbuhl, A., Curry, J. M. & South, A. P. 30 May 2016 8, 5, p. 2432-2437 6 p.

    Research output: Contribution to journalArticle

  7. Connexin30.2: In vitro interaction with connexin36 in hela cells and expression in AII amacrine cells and intrinsically photosensitive ganglion cells in the mouse retina

    Meyer, A., Tetenborg, S., Greb, H., Segelken, J., Dorgau, B., Weiler, R., Hormuzdi, S. G., Janssen-Bienhold, U. & Dedek, K. 27 May 2016 In : Frontiers in Molecular Neuroscience. 9, MAY, 17 p., 36

    Research output: Contribution to journalArticle

  8. Outcome of phacoemulsification and intraocular lens implantion in eyes with pseudoexfoliation and weak zonules

    Shingleton, B. J., Neo, Y. N., Cvintal, V., Shaikh, A. M., Liberman, P. & O'Donoghue, M. W. 27 May 2016 In : Acta Ophthalmologica. 6 p., 13110

    Research output: Contribution to journalArticle

  9. Thyroxine replacement: a clinical endocrinologist’s viewpoint

    Eligar, V., Taylor, P. N., Okosieme, O. E., Leese, G. P. & Dayan, C. M. 27 May 2016 In : Annals of Clinical Biochemistry. 53, 4, p. 421-433 13 p.

    Research output: Contribution to journalArticle

  10. Evidence-based guidelines for treating bipolar disorder: Revised third edition recommendations from the British Association for Psychopharmacology

    Goodwin, G. M. , Haddad, P. M. , Ferrier, I. N. , Aronson, J. K. , Barnes, T. R. H. , Cipriani, A. , Coghill, D. R. , Fazel, S. , Geddes, J. R. , Grunze, H. , Holmes, E. A. , Howes, O. , Hudson, S. , Hunt, N. , Jones, I. , MacMillan, I. C. , McAllister-Williams, H. , Miklowitz, D. R. , Morriss, R. & 8 others Munafò, M., Paton, C., Saharkian, B. J., Saunders, K. E. A., Sinclair, J. M. A., Taylor, D., Vieta, E. & Young, A. H. 10 May 2016 In : Journal of Psychopharmacology. 30, 6, p. 495-553 59 p.

    Research output: Contribution to journalArticle

  11. Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD

    Rabinovich, R. A., Miller, B. E., Wrobel, K., Ranjit, K., Williams, M. C., Drost, E., Edwards, L. D., Lomas, D. A., Rennard, S. I., Agustí, A., Tal-Singer, R., Vestbo, J., Wouters, E. F. M., John, M., Van Beek, E. J. R., Murchison, J. T., Bolton, C. E., Macnee, W. & Huang, J. T. J. 1 May 2016 In : European Respiratory Journal. 47, 5, p. 1365-1373 9 p.

    Research output: Contribution to journalArticle

  12. Can antioxidant-rich blackcurrant juice drink consumption improve photoprotection against ultraviolet radiation?

    Ray, S., Belch, J. J., Craigie, A. M., Khan, F., Kennedy, G., Hill, A., Barton, K. L., Dawe, R. S. & Ibbotson, S. H. May 2016 In : British Journal of Dermatology. 174, 5, p. 1101-1103 3 p.

    Research output: Contribution to journalLetter

  13. Development and validation of a model to predict absolute vascular risk reduction by moderate-intensity statin therapy in individual patients with type 2 diabetes mellitus

    Kaasenbrood, L., Poulter, N. R., Sever, P. S., Colhoun, H. M., Livingstone, S. J., Boekholdt, S. M., Pressel, S. L., Davis, B. R., Van Der Graaf, Y. & Visseren, F. L. J. May 2016 9, 3, p. 213-221 9 p.

    Research output: Contribution to journalArticle

  14. Nrf2 activation in the treatment of neurodegenerative diseases: A focus on its role in mitochondrial bioenergetics and function

    Esteras, N., Dinkova-Kostova, A. T. & Abramov, A. Y. May 2016 In : Biological Chemistry. 397, 5, p. 383-400 18 p.

    Research output: Contribution to journalArticle

  15. Spironolactone for people aged 70 or over with osteoarthritic knee pain: a proof-of-concept trial

    McMurdo, M. E. T., Sumukadas, D., Donnan, P. T., Cvoro, V., Rauchhaus, P., Argo, I., Waldie, H., Littleford, R., Struthers, A. D. & Witham, M. D. May 2016 In : Arthritis Care & Research. 68, 5, p. 716-721 6 p.

    Research output: Contribution to journalArticle

  16. Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug

    Cameron, A., Logie, L., Patel, K., Bacon, S., Forteath, C., Harthill, J., Roberts, A., Sutherland, C., Stewart, D., Viollet, B., Sakamoto, K., McDougall, G., Foretz, M. & Rena, G. Aug 2016 In : Biochimica et Biophysica Acta. Molecular Basis of Disease. 1862, 8, p. 1412-1422 11 p.

    Research output: Contribution to journalArticle

  17. Adherence to antiepileptic drugs in children with epilepsy in a Scottish population cohort

    Shetty, J., Greene, S. A., Mesalles-Naranjo, O. & Kirkpatrick, M. 22 Apr 2016 In : Developmental Medicine and Child Neurology. 58, 5, p. 469-474 6 p., 12942

    Research output: Contribution to journalArticle

  18. In vivo validation of spatio-temporal liver motion prediction from motion tracked on MR thermometry images

    Tanner, C., Zur, Y., French, K., Samei, G., Strehlow, J., Sat, G., McLeod, H., Houston, G., Kozerke, S., Székely, G., Melzer, A. & Preusser, T. 12 Apr 2016 In : International Journal of Computer Assisted Radiology and Surgery. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  19. The essentiality of arachidonic acid in infant development

    Hadley, K. B., Ryan, A. S., Forsyth, S., Gautier, S. & Salem, N. 12 Apr 2016 In : Nutrients. 8, 4, 47 p., 216

    Research output: Contribution to journalArticle

  20. Synthesis, molecular modeling and NAD(P)H: quinone oxidoreductase 1 inducer activity of novel 2-phenylquinazolin-4-amine derivatives

    Ghorab, M. M., Alsaid, M. S., Higgins, M., Dinkova-Kostova, A. T., Shahat, A. A., Elghazawy, N. H. & Arafa, R. K. 7 Apr 2016 In : Journal of Enzyme Inhibition and Medicinal Chemistry. p. 1-7 7 p.

    Research output: Contribution to journalArticle

  21. Should studies of diabetes treatment stratification correct for baseline HbA1c?

    Jones, A. G., Lonergan, M., Henley, W. E., Pearson, E. R., Hattersley, A. T. & Shields, B. M. 6 Apr 2016 In : PLoS ONE. 11, 4, 14 p., e0152428

    Research output: Contribution to journalArticle

  22. The heparan sulfate sulfotransferase 3-OST3A (HS3ST3A) is a novel tumor regulator and a prognostic marker in breast cancer

    Mao, X., Gauche, C., Coughtrie, M. W. H., Bui, C., Gulberti, S., Merhi-Soussi, F., Ramalanjaona, N., Bertin-Jung, I., Diot, A., Dumas, D., De Freitas Caires, N., Thompson, A. M., Bourdon, J-C., Ouzzine, M. & Fournel-Gigleux, S. 4 Apr 2016 In : Oncogene. 13 p.

    Research output: Contribution to journalArticle

  23. Altered metabolic parameters in association with antipsychotic medication use in diabetes: A population based case-control study

    Wake, D. J., Broughton, P., Perera, S. M., MacIntyre, D. J. & Leese, G. P. 1 Apr 2016 In : Psychoneuroendocrinology. 66, p. 214-220 7 p.

    Research output: Contribution to journalArticle

  24. Making the invisible visible

    van Steensel, M. A. M. 1 Apr 2016 In : Seminars in Cell & Developmental Biology. 52, p. 58-65 8 p.

    Research output: Contribution to journalArticle

  25. Chemical constituents and NAD(P)H:Quinone oxidoreductase 1 (NQO1) inducer activity of Teucrium oliverianum Ging. ex Benth

    Shahat, A. A., Alsaid, M. S., Khan, J. A., Higgins, M. & Dinkova-Kostova, A. T. Apr 2016 In : Indian Journal of Traditional Knowledge. 15, 2, p. 232-236 5 p.

    Research output: Contribution to journalArticle

  26. During postnatal development endogenous neurosteroids influence GABA-ergic neurotransmission of mouse cortical neurons

    Brown, A. R., Mitchell, S., Peden, D. R., Herd, M. B., Seifi, M., Swinny, J. D., Belelli, D. & Lambert, J. Apr 2016 In : Neuropharmacology. 103, p. 163-173 11 p.

    Research output: Contribution to journalArticle

  27. Effects of adding Tiotropium or Aclidinium as triple therapy using impulse oscillometry in COPD

    Manoharan, A., Morrison, A. E. & Lipworth, B. Apr 2016 In : Lung. 194, 2, p. 259-266 8 p.

    Research output: Contribution to journalArticle

  28. Efficacy of the ulnar-basilic arteriovenous fistula for hemodialysis: a systematic review

    Al Shakarchi, J., Khawaja, A., Cassidy, D., Houston, J. G. & Inston, N. Apr 2016 In : Annals of Vascular Surgery. 32, p. 1-4 4 p.

    Research output: Contribution to journalArticle

  29. Feasibility and acceptability of TRANSFoRm to improve clinical trial recruitment in primary care

    Mastellos, N., Bliźniuk, G., Czopnik, D., McGilchrist, M., Misiaszek, A., Bródka, P., Curcin, V., Car, J., Delaney, B. C. & Andreasson, A. Apr 2016 In : Family Practice. 33, 2, p. 186-191 6 p., cmv102

    Research output: Contribution to journalArticle

  30. How does sex influence multimorbidity? Secondary analysis of a large nationally representative dataset

    Agur, K., McLean, G., Hunt, K., Guthrie, B. & Mercer, S. W. Apr 2016 In : International Journal of Environmental Research and Public Health. 13, 4, 12 p., 391

    Research output: Contribution to journalArticle

  31. Intravenous regional anaesthesia

    Checketts, M. R. Apr 2016 In : Anaesthesia and Intensive Care Medicine. 17, 4, p. 192-193 2 p.

    Research output: Contribution to journalArticle

  32. Is Gly16Arg β2 Receptor Polymorphism Related to Impulse Oscillometry in a Real-Life Asthma Clinic Setting?

    Jabbal, S., Manoharan, A., Lipworth, J., Anderson, W., Short, P. & Lipworth, B. Apr 2016 In : Lung. 194, 2, p. 267-271 5 p.

    Research output: Contribution to journalArticle

  33. Locally advanced basal cell carcinoma has a distinct methylation and transcriptomic profile

    Brinkhuizen, T., van Geel, M., Denil, S. L. I. J., De Meyer, T., Kelleners-Smeets, N. W. J., Lohuis, P. J. F. M., Hoebers, F. J. P., Winnepenninckx, V. J. L., van Steensel, M. A. M. & Mosterd, K. Apr 2016 In : Experimental Dermatology. 25, 4, p. 316-318 3 p.

    Research output: Contribution to journalLetter

  34. Post Hoc Analysis of Potential Predictors of Response to Atomoxetine for the Treatment of Adults with Attention-Deficit/Hyperactivity Disorder using an Integrated Database

    Bushe, C., Sobanski, E., Coghill, D., Berggren, L., De Bruyckere, K. & Leppämäki, S. Apr 2016 In : CNS Drugs. 30, 4, p. 317-334 18 p.

    Research output: Contribution to journalArticle

  35. Practical aspects of ultrasound-guided regional anaesthesia

    Raju, P. K. B. C. & Grant, C. R. K. Apr 2016 In : Anaesthesia and Intensive Care Medicine. 17, 4, p. 171-174 4 p.

    Research output: Contribution to journalArticle

  36. Systemic toxic effects of local anaesthetics

    Beecroft, C. & Davies, G. Apr 2016 In : Anaesthesia and Intensive Care Medicine. 17, 4, p. 179-181 3 p.

    Research output: Contribution to journalArticle

  37. The prevalence and impact of thrombocytopenia, anaemia and leucopenia on sustained virological response in patients receiving hepatitis C therapy: evidence from a large ‘real world’ cohort

    Wang, H., Innes, H., Hutchinson, S. J., Goldberg, D. J., Allen, S., Barclay, S. T., Bramley, P., Fox, R., Fraser, A., Hayes, P. C., Kennedy, N., Mills, P. R. & Dillon, J. F. Apr 2016 In : European Journal of Gastroenterology & Hepatology. 28, 4, p. 398-404 7 p.

    Research output: Contribution to journalArticle

  38. Upper limb nerve blocks

    Coventry, D. M. & Raju, P. K. B. C. Apr 2016 In : Anaesthesia and Intensive Care Medicine. 17, 4, p. 187-191 5 p.

    Research output: Contribution to journalArticle

  39. Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease

    Morris, A. D. & 128 others Stitziel, N. O., Stirrups, K. E., Masca, N. G. D., Erdmann, J., Ferrario, P. G., König, I. R., Weeke, P. E., Webb, T. R., Auer, P. L., Schick, U. M., Lu, Y., Zhang, H., Dube, M. P., Goel, A., Farrall, M., Peloso, G. M., Won, H. H., Do, R., Van Iperen, E., Kanoni, S., Kruppa, J., Mahajan, A., Scott, R. A., Willenborg, C., Braund, P. S., Van Capelleveen, J. C., Doney, A. S. F., Donnelly, L. A., Asselta, R., Merlini, P. A., Duga, S., Marziliano, N., Denny, J. C., Shaffer, C. M., El-Mokhtari, N. E., Franke, A., Gottesman, O., Heilmann, S., Hengstenberg, C., Hoffmann, P., Holmen, O. L., Hveem, K., Jansson, J. H., Jöckel, K. H., Kessler, T., Kriebel, J., Laugwitz, K. L., Marouli, E., Martinelli, N., McCarthy, M. I., van Zuydam, N. R., Meisinger, C., Esko, T., Mihailov, E., Escher, S. A., Alver, M., Moebus, S., Müller-Nurasyid, M., Nikpay, M., Olivieri, O., Perreault, L. P. L., AlQarawi, A., Robertson, N. R., Akinsanya, K. O., Reilly, D. F., Vogt, T. F., Yin, W., Asselbergs, F. W., Kooperberg, C., Jackson, R. D., Stahl, E., Strauch, K., Varga, T. V., Waldenberger, M., Zeng, L., Kraja, A. T., Liu, C., Ehret, G. B., Newton-Cheh, C., Chasman, D. I., Chowdhury, R., Ferrario, M., Ford, I., Jukema, J. W., Kee, F., Kuulasmaa, K., Nordestgaard, B. G., Perola, M., Saleheen, D., Sattar, N., Surendran, P., Tregouet, D., Young, R., Howson, J. M. M., Butterworth, A. S., Danesh, J., Ardissino, D., Bottinger, E. P., Erbel, R., Franks, P. W., Girelli, D., Hall, A. S., Hovingh, G. K., Kastrati, A., Lieb, W., Meitinger, T., Kraus, W. E., Shah, S. H., McPherson, R., Orho-Melander, M., Melander, O., Metspalu, A., Palmer, C. N. A., Peters, A., Rader, D. J., Reilly, M. P., Loos, R. J. F., Reiner, A. P., Roden, D. M., Tardif, J. C., Thompson, J. R., Wareham, N. J., Watkins, H., Willer, C. J., Kathiresan, S., Deloukas, P., Samani, N. J. & Schunkert, H. 24 Mar 2016 In : New England Journal of Medicine. 374, 12, p. 1134-1144 11 p.

    Research output: Contribution to journalArticle

  40. Safer Prescribing: A Trial of Education, Informatics, and Financial Incentives

    Dreischulte, T., Donnan, P., Grant, A., Hapca, A., McCowan, C. & Guthrie, B. 17 Mar 2016 In : New England Journal of Medicine. 374, 11, p. 1053-1064 12 p.

    Research output: Contribution to journalArticle

  41. Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation

    Orriss, I. R., Arnett, T. R., George, J. & Witham, M. D. 15 Mar 2016 In : Experimental Cell Research. 342, 2, p. 166-174 9 p.

    Research output: Contribution to journalArticle

  42. Changes in autofluorescence based organoid model of muscle invasive urinary bladder cancer

    Palmer, S., Litvinova, K., Dunaev, A., Fleming, S., McGloin, D. & Nabi, G. 7 Mar 2016 In : Biomedical Optics Express. 7, 4, p. 1193-2000 8 p.

    Research output: Contribution to journalArticle

  43. The loop structure and the RNA helicase p72/DDX17 influence the processing efficiency of the mice miR-132

    Remenyi, J., Bajan, S., Fuller-Pace, F. V., Arthur, J. S. C. & Hutvagner, G. 7 Mar 2016 In : Scientific Reports. 6, 13 p., 22848

    Research output: Contribution to journalArticle

  44. S-palmitoylation and the regulation of NCX1

    Fuller, W., Reilly, L. & Hilgemann, D. W. 3 Mar 2016 In : Channels. 10, 2, p. 75-77 3 p.

    Research output: Contribution to journalArticle

  45. Association between allopurinol use and hip fracture in older patients

    Basu, U., Goodbrand, J., McMurdo, M. E. T., Donnan, P. T., McGilchrist, M., Frost, H., George, J. & Witham, M. D. Mar 2016 In : Bone. 84, p. 189-193 5 p.

    Research output: Contribution to journalArticle

  46. Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population

    Smith, B. H. & 22 others Clarke, T. K., Lupton, M. K., Fernandez-Pujals, A. M., Starr, J., Davies, G., Cox, S., Pattie, A., Liewald, D. C., Hall, L. S., MacIntyre, D. J., Hocking, L. J., Padmanabhan, S., Thomson, P. A., Hayward, C., Hansell, N. K., Montgomery, G. W., Medland, S. E., Martin, N. G., Wright, M. J., Porteous, D. J., Deary, I. J. & McIntosh, A. M. Mar 2016 In : Molecular Psychiatry. 21, 3, p. 419-425 7 p.

    Research output: Contribution to journalArticle

  47. Effects of formoterol or salmeterol on impulse oscillometry in persistent asthma

    Manoharan, A., von Wilamowitz-Moellendorff, A., Morrison, A. & Lipworth, B. J. Mar 2016 In : Journal of Allergy and Clinical Immunology. 137, 3, p. 727-733.e1 8 p.

    Research output: Contribution to journalArticle

  48. Photodynamic diagnostic ureterorenoscopy: a valuable tool in the detection of upper urinary tract tumour

    Kata, S. G., Aboumarzouk, O. M., Zreik, A., Somani, B., Ahmad, S., Nabi, G., Buist, R., Goodman, C., Chlosta, P., Golabek, T. & Moseley, H. Mar 2016 In : Photodiagnosis and Photodynamic Therapy. 13, p. 255-260 6 p.

    Research output: Contribution to journalArticle

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