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  1. Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment

    Mace, P. D., Linke, K., Feltham, R., Schumacher, F-R., Smith, C. A., Vaux, D. L., Silke, J. & Day, C. L. 2008 In : Journal of Biological Chemistry. 283, 46, p. 31633-31640 8 p.

    Research output: Contribution to journalArticle

  2. The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys(63)-linked polyubiquitination of IRAK1

    Ordureau, A., Smith, H., Windheim, M., Peggie, M., Carrick, E., Morrice, N. & Cohen, P. 2008 In : Biochemical Journal. 409, 1, p. 43-52 10 p.

    Research output: Contribution to journalArticle

  3. The selectivity of protein kinase inhibitors: a further update

    Bain, J., Plater, L., Elliott, M., Shpiro, N., Hastie, C. J., Mclauchlan, H., Klevernic, I., Arthur, J. S. C., Alessi, D. R. & Cohen, P. 15 Dec 2007 In : Biochemical Journal. 408, p. 297-315 19 p.

    Research output: Contribution to journalArticle

  4. BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo

    Sapkota, G. P., Cummings, L., Newell, F. S., Armstrong, C., Bain, J., Frodin, M., Grauert, M., Hoffmann, M., Schnapp, G., Steegmaier, M., Cohen, P. & Alessi, D. R. 16 Oct 2007 In : Biochemical Journal. 401, 1, p. 29-38 10 p.

    Research output: Contribution to journalArticle

  5. Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR

    Geraghty, K. M., Chen, S., Harthill, J. E., Ibrahim, A. F., Toth, R., Morrice, N. A., Vandermoere, F., Moorhead, G. B., Hardie, D. G. & MacKintosh, C. 15 Oct 2007 In : Biochemical Journal. 407, p. 231-241 11 p.

    Research output: Contribution to journalArticle

  6. Identification of protor as a novel rictor-binding component of mTOR complex-2

    Pearce, L. R., Huang, X., Boudeau, J., Pawłowski, R., Wullschleger, S., Deak, M., Ibrahim, A. F. M., Gourlay, R., Magnuson, M. A. & Alessi, D. R. 1 Aug 2007 In : Biochemical Journal. 405, 3, p. 513-522 10 p.

    Research output: Contribution to journalArticle

  7. Targeting of TMV movement protein to plasmodesmata requires the actin/ER network: evidence from FRAP

    Wright, K. M., Wood, N. T., Roberts, A. G., Chapman, S., Boevink, P., MacKenzie, K. M. & Oparka, K. J. Jan 2007 In : Traffic. 8, 1, p. 21-31 11 p.

    Research output: Contribution to journalArticle

  8. UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination

    Alpi, A., Langevin, F., Mosedale, G., Machida, Y. J., Dutta, A. & Patel, K. J. 2007 In : Molecular and Cellular Biology. 27, 24, p. 8421-8430 10 p.

    Research output: Contribution to journalArticle

  9. TAK1-binding protein 1 is a pseudophosphatase

    Conner, S. H., Kular, G., Peggie, M., Shepherd, S., Schüttelkopf, A. W., Cohen, P. & van Aalten, D. M. F. 1 Nov 2006 In : Biochemical Journal. 399, 3, p. 427-434 8 p.

    Research output: Contribution to journalArticle

  10. The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells

    Cartlidge, R. A., Knebel, A., Peggie, M., Alexandrov, A., Phizicky, E. M. & Cohen, P. May 2005 In : The EMBO Journal. 24, 9, p. 1696-1705 10 p.

    Research output: Contribution to journalArticle

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