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Scottish Institute for ceLL Signalling

  1. Oligomerization conditions Mdm2-mediated efficient p53 polyubiquitylation but not its proteasomal degradation

    Hjerpe, R., Aillet, F., Lopitz-Otsoa, F., Lang, V., Torres-Ramos, M., Farras, R., Hay, R. T. & Rodriguez, M. S. May 2010 In : International Journal of Biochemistry & Cell Biology. 42, 5, p. 725-735 11 p.

    Research output: Contribution to journalArticle

  2. Semisynthetic Src SH2 domains demonstrate altered phosphopeptide specificity induced by incorporation of unnatural lysine derivatives

    Virdee, S., Macmillan, D. & Waksman, G. 26 Mar 2010 In : Chemistry & Biology. 17, 3, p. 274-284 11 p.

    Research output: Contribution to journalArticle

  3. Molecular mechanism of elongation factor 1A inhibition by a Legionella pneumophila glycosyltransferase

    Hurtado-Guerrero, R., Zusman, T., Pathak, S., Ibrahim, A. F. M., Shepherd, S., Prescott, A., Segal, G. & van Aalten, D. M. F. 15 Mar 2010 In : Biochemical Journal. 426, p. 281-292 12 p.

    Research output: Contribution to journalArticle

  4. Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation

    Cohen, P. 1 Jan 2010 In : Biochemical Journal. 425, p. 53-54 2 p.

    Research output: Contribution to journalLiterature review

  5. An improved SUMmOn-based methodology for the identification of ubiquitin and ubiquitin-like protein conjugation sites identifies novel ubiquitin-like protein chain linkages

    Jeram, S. M., Srikumar, T., Zhang, X-D., Eisenhauer, H. A., Rogers, R., Pedrioli, P. G. A., Matunis, M. & Raught, B. 2010 In : Proteomics. 10, 2, p. 254-265 12 p.

    Research output: Contribution to journalArticle

  6. Glycogen synthase kinase 3

    Cohen, P. & Frame, S. 2010 Handbook of cell signaling. Bradshaw, R. A. & Dennis, E. A. (eds.). 2nd ed. London: Academic Press, Vol. 2, p. 569-573 5 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  7. Phosphatase families dephosphorylating serine and threonine residues in proteins

    Cohen, P. T. W. 2010 Handbook of cell signaling. Bradshaw, R. A. & Dennis, E. A. (eds.). 2nd ed. London: Academic Press, Vol. 2, p. 659-675 17 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  8. Phosphoproteomic Analysis Reveals Interconnected System-Wide Responses to Perturbations of Kinases and Phosphatases in Yeast

    Bodenmiller, B. , Wanka, S. , Kraft, C. , Urban, J. , Campbell, D. , Pedrioli, P. G. , Gerrits, B. , Picotti, P. , Lam, H. , Vitek, O. , Brusniak, M-Y. , Roschitzki, B. , Zhang, C. , Shokat, K. M. , Schlapbach, R. , Colman-Lerner, A. , Nolan, G. P. , Nesvizhskii, A. I. , Peter, M. & 3 others Loewith, R., von Mering, C. & Aebersold, R. 2010 In : Science Signaling. 3, 153, p. - 8 p., rs4

    Research output: Contribution to journalArticle

  9. Cullin neddylation and substrate-adaptors counteract SCF inhibition by the CAND1-like protein Lag2 in Saccharomyces cerevisiae

    Siergiejuk, E., Scott, D. C., Schulman, B. A., Hofmann, K., Kurz, T. & Peter, M. 16 Dec 2009 In : EMBO Journal. 28, 24, p. 3845-3856 12 p.

    Research output: Contribution to journalArticle

  10. Biochemical characterisation of the SWI/SNF family member HLTF

    MacKay, C., Toth, R. & Rouse, J. 11 Dec 2009 In : Biochemical and Biophysical Research Communications. 390, 2, p. 187-191 5 p.

    Research output: Contribution to journalArticle

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