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  1. The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system

    Strickson, S., Campbell, D. G., Emmerich, C. H., Knebel, A., Plater, L., Ritorto, M. S., Shpiro, N. & Cohen, P. 1-May-2013 In : Biochemical Journal. 451, 3, p. 427-437, 11 p.

    Research output: Contribution to journal › Article

  2. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability

    Bett, J. S., Ibrahim, A. F. M., Garg, A. K., Kelly, V., Pedrioli, P., Rocha, S. & Hay, R. T. 15-Apr-2013 In : Biochemical Journal. 451, 2, p. 185-194, 10 p., BJ20130026

    Research output: Contribution to journal › Article

  3. The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction

    Ohta, A., Schumacher, F-R., Mehellou, Y., Johnson, C., Knebel, A., Macartney, T. J., Wood, N. T., Alessi, D. R. & Kurz, T. 1-Apr-2013 In : Biochemical Journal. 451, 1, p. 111-122, 12 p.

    Research output: Contribution to journal › Article

  4. CSN-and CAND1-dependent remodelling of the budding yeast SCF complex

    Zemla, A., Thomas, Y., Kedziora, S., Knebel, A., Wood, N. T., Rabut, G. & Kurz, T. 27-Mar-2013 In : Nature Communications. 4, 1641

    Research output: Contribution to journal › Article

  5. PGE2 Induces Macrophage IL-10 Production and a Regulatory-like Phenotype via a Protein Kinase A-SIK-CRTC3 Pathway

    Mackenzie, K. F., Clark, K., Naqvi, S., McGuire, V. A., Nöehren, G., Kristariyanto, Y., van den Bosch, M., Mudaliar, M., McCarthy, P. C., Pattison, M. J., Pedrioli, P. G. A., Barton, G. J., Toth, R., Prescott, A. & Arthur, J. S. C. 15-Jan-2013 In : Journal of Immunology. 190, 2, p. 565-77, 13 p.

    Research output: Contribution to journal › Article

  6. Hydrophilic Strong Anion Exchange (hSAX) Chromatography for Highly Orthogonal Peptide Separation of Complex Proteomes

    Ritorto, M. S., Cook, K., Tyagi, K., Pedrioli, P. G. A. & Trost, M. 2013 In : Journal of Proteome Research.

    Research output: Contribution to journal › Article

  7. Kinase drug discovery: What's next in the field?

    Cohen, P. & Alessi, D. R. 2013 In : ACS Chemical Biology. 8, 1, p. 96-104, 9 p.

    Research output: Contribution to journal › Article

  8. Heterologous SUMO-2/3-Ubiquitin Chains Optimize IκBα Degradation and NF-κB Activity

    Aillet, F., Lopitz-Otsoa, F., Egaña, I., Hjerpe, R., Fraser, P., Hay, R. T., Rodriguez, M. S. & Lang, V. 20-Dec-2012 In : PLoS ONE. 7, 12, e51672

    Research output: Contribution to journal › Article

  9. Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases

    McIver, E. G., Bryans, J., Birchall, K., Chugh, J., Drake, T., Lewis, S. J., Osborne, J., Smiljanic-Hurley, E., Tsang, W., Kamal, A., Levy, A., Newman, M., Taylor, D., Arthur, J. S. C., Clark, K. & Cohen, P. Dec-2012 In : Bioorganic & Medicinal Chemistry Letters. 22, 23, p. 7169-7173, 5 p.

    Research output: Contribution to journal › Article

  10. NEDD8 overexpression results in neddylation of ubiquitin substrates by the ubiquitin pathway

    Hjerpe, R., Thomas, Y. & Kurz, T. Aug-2012 In : Journal of Molecular Biology. 421, 1, p. 27-9, 3 p.

    Research output: Contribution to journal › Article

  11. The IkappaB kinase family phosphorylates the Parkinson's disease kinase LRRK2 at Ser935 and Ser910 during Toll-Like Receptor signaling

    Dzamko, N., Inesta-Vaquera, F., Zhang, J., Arthur, S., Cohen, P., Clark, K., Alessi, D. R., Xie, C., Cai, H., Tan, L., Choi, H., Gray, N. & Pedrioli, P. 18-Jun-2012 In : PLoS ONE. 7, 6, e39132

    Research output: Contribution to journal › Article

  12. Essential Role for IKK beta in Production of Type 1 Interferons by Plasmacytoid Dendritic Cells

    Pauls, E., Shpiro, N., Peggie, M., Young, E. R., Sorcek, R. J., Tan, L., Choi, H. G. & Cohen, P. 1-Jun-2012 In : Journal of Biological Chemistry. 287, 23, p. 19216-19228, 13 p.

    Research output: Contribution to journal › Article

  13. UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1 alpha accumulation

    Bandau, S., Knebel, A., Gage, Z. O., Wood, N. T. & Alexandru, G. 26-Apr-2012 In : BMC Biology. 10, p. -, 15 p., 36

    Research output: Contribution to journal › Article

  14. O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release

    Pathak, S., Borodkin, V. S., Albarbarawi, O., Campbell, D. G., Ibrahim, A. & van Aalten, D. M. F. 21-Mar-2012 In : EMBO Journal. 31, 6, p. 1394-1404, 11 p.

    Research output: Contribution to journal › Article

  15. Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes

    Hjerpe, R., Thomas, Y., Chen, J., Zemla, A., Curran, S., Shpiro, N., Dick, L. R. & Kurz, T. 1-Feb-2012 In : Biochemical Journal. 441, p. 927-936, 10 p.

    Research output: Contribution to journal › Article

  16. The Vibrio cholerae colonization factor GbpA possesses a modular structure that governs binding to different host surfaces

    Wong, E., Vaaje-Kolstad, G., Ghosh, A., Hurtado-Guerrero, R., Konarev, P. V., Ibrahim, A. F. M., Svergun, D. I., Eijsink, V. G. H., Chatterjee, N. S. & van Aalten, D. M. F. 12-Jan-2012 In : PLoS Pathogens. 8, 1, e1002373

    Research output: Contribution to journal › Article

  17. Exploring the role of p97 and its UBX-domain cofactors through identification of their interacting proteins

    Alexandru, G. 1-Jan-2012 Methods in Molecular Biology: Ubiquitin Family Modifiers and the Proteasome. Springer, Vol. 832, p. 305-312 8 p.

    Research output: Chapter in Book/Report/Conference proceeding › Other chapter contribution

  18. Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system

    Goh, E. T. H., Arthur, J. S. C., Cheung, P. C. F., Akira, S., Toth, R. & Cohen, P. 1-Jan-2012 In : Biochemical Journal. 441, p. 339-346, 8 p.

    Research output: Contribution to journal › Article

  19. An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains

    Licchesi, J. D. F., Mieszczanek, J., Mevissen, T. E. T., Rutherford, T. J., Akutsu, M., Virdee, S., El Oualid, F., Chin, J. W., Ovaa, H., Bienz, M. & Komander, D. Jan-2012 In : Nature Structural & Molecular Biology. 19, 1, p. 62-U83, 11 p.

    Research output: Contribution to journal › Article

  20. Pellino1 Is Required for Interferon Production by Viral Double-stranded RNA

    Enesa, K., Ordureau, A., Smith, H., Barford, D., Cheung, P. C. F., Patterson-Kane, J., Arthur, J. S. C. & Cohen, P. 2012 In : Journal of Biological Chemistry. 287, 41, p. 34825-34835, 11 p.

    Research output: Contribution to journal › Article

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