BindingDB Entry 50008275: Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis.

BindingDB
Michael Thomas (Creator)
Manu De Rycker (Creator)
Myriam Ajakane (Creator)
Sébastian Albrecht (Creator)
Ana Isabel Álvarez-Pedraglio (Creator)
Markus Boesche (Creator)
Stephen Brand (Creator)
Lorna Campbell (Creator)
Juan Cantizani-Perez (Creator)
Laura Cleghorn (Creator)
Royston C B Copley (Creator)
Sabrinia D. Crouch (Creator)
Alain Daugan (Creator)
Gerard Drewes (Creator)
Santiago Ferrer-Bazaga (Creator)
Sonja Ghidelli-Disse (Creator)
Silvia Gonzalez (Creator)
Stephanie L. Gresham (Creator)
Alan P. Hill (Creator)
Sean J. Hindley (Creator)
Rhiannon M. Lowe (Creator)
Claire Mackenzie (Creator)
Lorna MacLean (Creator)
Sujatha Manthri (Creator)
Franck Martin (Creator)
Juan Miguel-Siles (Creator)
Suzanne Norval (Creator)
Maria Osuna-Cabello (Creator)
Andrew Woodland (Creator)
Stephen Patterson (Creator)
Imanol Pena (Creator)
Maria Teresa Quesada-Campos (Creator)
Iain H. Reid (Creator)
Charlotte Revill (Creator)
Jennifer Riley (Creator)
Jose Ramon Ruiz-Gomez (Creator)
Yoko Shishikura (Creator)
Frederick Simeons (Creator)
Victoria C. Smith (Creator)
Daniel Spinks (Creator)
Laste Stojanovski (Creator)
John Thomas (Creator)
Stephen Thompson (Creator)
Tim Z. Underwood (Creator)
David Gray (Creator)
Jose Maria Fiandor (Creator)
Ian Gilbert (Creator)
Paul Wyatt (Creator)
Kevin Read (Creator)
Timothy J. Miles (Creator)

Dataset

Description

Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cyclin-dependent kinase 2, Cyclin-dependent kinase 4, and Cytochrome P450 3A4, Uniprot P08684, P11802, P24941, and P40989

Date made available	22 Feb 2021
Publisher	BindingDB

Keywords

1,3-beta-glucan synthase component GSC2, Cyclin-dependent kinase 2, Cyclin-dependent kinase 4, and Cytochrome P450 3A4, University of Dundee, Affinity

Contact

[email protected]

DOI
10.7270/q2zc867r

2 Finished

A Translational Engine for Biomedical Discoveries (Strategic Grant)
Fairlamb, A. (Investigator) & Gilbert, I. (Investigator)
1/01/13 → 30/09/15
Project: Research
Discovery and Development of Drug Candidates for Neglected Diseases (joint with industrial partner)
Brenk, R. (Investigator), Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Hopkins, A. (Investigator), Horn, D. (Investigator), Read, K. (Investigator), Wyatt, P. (Investigator) & van Aalten, D. (Investigator)
1/02/11 → 1/07/17
Project: Research

1 Article

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis
Thomas, M. G., De Rycker, M., Ajakane, M., Albrecht, S., Álvarez-Pedraglio, A. I., Boesche, M., Brand, S., Campbell, L., Cantizani-Perez, J., Cleghorn, L. A. T., Copley, R. C. B., Crouch, S. D., Daugan, A., Drewes, G., Ferrer, S., Ghidelli-Disse, S., Gonzalez, S., Gresham, S. L., Hill, A. P. & Hindley, S. J. & 32 others, Lowe, R. M., MacKenzie, C. J., MacLean, L., Manthri, S., Martin, F., Miguel-Siles, J., Nguyen, V. L., Norval, S., Osuna-Cabello, M., Woodland, A., Patterson, S., Pena, I., Quesada-Campos, M. T., Reid, I. H., Revill, C., Riley, J., Ruiz-Gomez, J. R., Shishikura, Y., Simeons, F. R. C., Smith, A., Smith, V. C., Spinks, D., Stojanovski, L., Thomas, J., Thompson, S., Underwood, T., Gray, D. W., Fiandor, J. M., Gilbert, I. H., Wyatt, P. G. (Lead / Corresponding author), Read, K. D. (Lead / Corresponding author) & Miles, T. J. (Lead / Corresponding author), 14 Feb 2019, In: Journal of Medicinal Chemistry. 62, 3, p. 1180-1202 23 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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44 Link opens in a new tab Citations (Scopus)

431 Downloads (Pure)

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DataSetCite

Thomas, M. (Creator), De Rycker, M. (Creator), Ajakane, M. (Creator), Albrecht, S. (Creator), Álvarez-Pedraglio, A. I. (Creator), Boesche, M. (Creator), Brand, S. (Creator), Campbell, L. (Creator), Cantizani-Perez, J. (Creator), Cleghorn, L. (Creator), Copley, R. C. B. (Creator), Crouch, S. D. (Creator), Daugan, A. (Creator), Drewes, G. (Creator), Ferrer-Bazaga, S. (Creator), Ghidelli-Disse, S. (Creator), Gonzalez, S. (Creator), Gresham, S. L. (Creator), Hill, A. P. (Creator), Hindley, S. J. (Creator), Lowe, R. M. (Creator), Mackenzie, C. (Creator), MacLean, L. (Creator), Manthri, S. (Creator), Martin, F. (Creator), Miguel-Siles, J. (Creator), Norval, S. (Creator), Osuna-Cabello, M. (Creator), Woodland, A. (Creator), Patterson, S. (Creator), Pena, I. (Creator), Quesada-Campos, M. T. (Creator), Reid, I. H. (Creator), Revill, C. (Creator), Riley, J. (Creator), Ruiz-Gomez, J. R. (Creator), Shishikura, Y. (Creator), Simeons, F. (Creator), Smith, V. C. (Creator), Spinks, D. (Creator), Stojanovski, L. (Creator), Thomas, J. (Creator), Thompson, S. (Creator), Underwood, T. Z. (Creator), Gray, D. (Creator), Fiandor, J. M. (Creator), Gilbert, I. (Creator), Wyatt, P. (Creator), Read, K. (Creator), Miles, T. J. (Creator) (22 Feb 2021). BindingDB Entry 50008275: Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis. BindingDB. 10.7270/q2zc867r

BindingDB Entry 50008275: Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis.

Description

Keywords

Contact

DOI

Projects

A Translational Engine for Biomedical Discoveries (Strategic Grant)

Discovery and Development of Drug Candidates for Neglected Diseases (joint with industrial partner)

Research output

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Cite this