Crystal Structure of compound 1-mediated ternary complex of KRAS G12R GCP with pVHL:ElonginC:ElonginB

Andre Wijaya (Creator)
Natalia Karolak (Creator)
Alessio Ciulli (Creator)

Centre for Targeted Protein Degradation

Dataset

Date made available	12 Nov 2025
Publisher	Protein Data Bank (PDB)

Contact

[email protected]

DOI
10.2210/pdb9rke/pdb

1 Article

Identification of a Highly Cooperative PROTAC Degrader Targeting GTP-loaded KRAS(on) Alleles
Vetma, V., Puoti, I., Karolak, N. K., Chakraborti, S., Diers, E., Girardi, E., Khan, S., Kidd, G., Kropatsch, K. G., Mclennan, R., O'Connor, S., Samwer, M., Trainor, N., Whitworth, C., Wijaya, A. J., Wong, J. Y. F., Zollman, D., Farnaby, W., Popow, J. & Ciulli, A. (Lead / Corresponding author) & 2 others, Ettmayer, P. (Lead / Corresponding author) & McAulay, K. (Lead / Corresponding author), 30 Oct 2025, (E-pub ahead of print) In: Journal of the American Chemical Society. 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File

Cite this