Crystal Structure of compound 3-mediated ternary complex of KRAS G12V C118S GDP with pVHL:ElonginC:ElonginB

David Zollman (Creator)
Natalia Karolak (Creator)
Alessio Ciulli (Creator)

Centre for Targeted Protein Degradation

Dataset

Description

PDB Entry - 9RK8 (pdb_00009rk8)

Date made available	26 Nov 2025
Publisher	Protein Data Bank (PDB)

Contact

[email protected]

DOI
10.2210/pdb9rk8/pdb

1 Article

Identification of a Highly Cooperative PROTAC Degrader Targeting GTP-loaded KRAS(on) Alleles
Vetma, V., Puoti, I., Karolak, N. K., Chakraborti, S., Diers, E., Girardi, E., Khan, S., Kidd, G., Kropatsch, K. G., Mclennan, R., O'Connor, S., Samwer, M., Trainor, N., Whitworth, C., Wijaya, A. J., Wong, J. Y. F., Zollman, D., Farnaby, W., Popow, J. & Ciulli, A. (Lead / Corresponding author) & 2 others, Ettmayer, P. (Lead / Corresponding author) & McAulay, K. (Lead / Corresponding author), 12 Nov 2025, In: Journal of the American Chemical Society. 147, 45, p. 41367-41378 12 p.
Research output: Contribution to journal › Article › peer-review

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