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Induced ubiquitination of the partially disordered Estrogen Receptor alpha protein via a 14-3-3-directed molecular glue-based PROTAC design

Dataset

Description

Source data includes raw data each replicate for biophysical experiments. Specifically, fluorescence polarization experiments and time-resolve fluorescence energy experiments transfer, the in-cell target engagement BRET assay, mass photometry experiments, ubiquitination mass spectrometry experiments.
Date made available1 Jan 2027
PublisherUniversity of Dundee

Keywords

  • Induce proximity
  • PROTAC
  • Drug discovery

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