PROTAC-mediated complex of KRAS with VHL/Elongin-B/Elongin-C/Cullin-2/Rbx1

Gerhard Fischer (Creator)
Daniel Peter (Boehringer Ingelheim RCV GmBH & Co KG) (Creator)
Silvia Arce-Solano (Boehringer Ingelheim RCV GmBH & Co KG) (Creator)
Alessio Ciulli (Creator)

Centre for Targeted Protein Degradation

Dataset

Date made available	6 Dec 2023
Publisher	Research Collaboratory for Structural Bioinformatics Protein Data Bank

Data Monitor categories

Drug development

Contact

[email protected]

DOI
10.2210/pdb8qu8/pdb

3 Finished

A Translational Engine for Biomedical Discoveries (Strategic Grant)
Fairlamb, A. (Investigator) & Gilbert, I. (Investigator)
1/01/13 → 30/09/15
Project: Research
Strategic Award: Wellcome Trust Technology Platform
Blow, J. (Investigator), Lamond, A. (Investigator) & Owen-Hughes, T. (Investigator)
1/01/13 → 30/09/18
Project: Research
State-of-the-Art Facilities for Structural Biology at the University of Dundee
Hunter, B. (Investigator), Lilley, D. (Investigator), Owen-Hughes, T. (Investigator), Wyatt, P. (Investigator) & van Aalten, D. (Investigator)
1/03/12 → 28/02/17
Project: Research

1 Article

Targeting cancer with small molecule pan-KRAS degraders
Popow, J., Farnaby, W., Gollner, A., Kofink, C., Fischer, G., Wurm, M., Zollman, D., Wijaya, A., Mischerikow, N., Hasenoehrl, C., Prokofeva, P., Arnhof, H., Arce-Solano, S., Bell, S., Boeck, G., Diers, E., Frost, A. B., Goodwin-Tindall, J., Karolyi-Oezguer, J. & Khan, S. & 23 others, Klawatsch, T., Koegl, M., Kousek, R., Kratochvil, B., Kropatsch, K., Lauber, A. A., McLennan, R., Olt, S., Peter, D., Petermann, O., Roessler, V., Stolt-Bergner, P., Strack, P., Strauss, E., Trainor, N., Vetma, V., Whitworth, C., Zhong, S., Quant, J., Weinstabl, H., Kuster, B., Ettmayer, P. (Lead / Corresponding author) & Ciulli, A. (Lead / Corresponding author), 20 Sept 2024, In: Science. 385, 6715, p. 1338-1347 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
19 Citations (Scopus)

242 Downloads (Pure)

Cite this