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      • 2017

        Factors associated with change in objectively measured physical activity in older people: data from the Physical Activity Cohort Scotland study

        Clarke, C., Sniehotta, F. F., Vadiveloo, T., Argo, I., Donnan, P., McMurdo, M. & Witham, M., 14 Aug 2017, In: BMC Geriatrics. 17, p. 1-9 9 p., 180.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        15 Citations (Scopus)
        164 Downloads (Pure)

      • Genetic variation in Kruppel like factor 15 is associated with left ventricular hypertrophy in patients with type 2 diabetes: discovery and replication cohorts

        Patel, S. K., Wai, B., Lang, C. C., Levin, D., Palmer, C. N. A., Parry, H. M., Velkoska, E., Harrap, S. B., Srivastava, P. M. & Burrell, L. M., Apr 2017, In: EBioMedicine. 18, p. 171-178 8 p.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        14 Citations (Scopus)
        86 Downloads (Pure)

      • Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

        Howard, D. M., Hall, L. S., Hafferty, J. D., Yanni, Z., Adams, M. J., Clarke, T-K., Porteous, D. J., Nagy, R., Hayward, C., Smith, B., Murray, A. D., Ryan, N. M., Evans, K. L., Haley, C. S., Deary, I. J., Thomson, P. A. & McIntosh, A. M., 30 Nov 2017, In: Translational Psychiatry. 7, p. 1-9 9 p., 1263.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        16 Citations (Scopus)
        161 Downloads (Pure)

      • Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

        Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K. L., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A., & 297 othersRenström, F., Wu, J. M. W., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg-Gresham, J. L., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Neergaard Harder, M., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, J. M., Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L-P., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-Nurasyid, M., Navarro, P., Pérusse, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stančáková, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S. W., van der Most, P. J., van Vliet-Ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Hua Zhao, J., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J. P., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E. P., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., de Borst, G. J., de Craen, A. J. M., de Geus, E. J. C., Dedoussis, G., Delgado, G. E., den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, N., Haitjema, S., Hallmans, G., Hamsten, A., Hansen, T., Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L. A., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Jan Hottenga, J., Huang, J., Hung, J., Hutri-Kähönen, N., Ingelsson, E., James, A. L., Jansson, J-O., Jarvelin, M-R., Jhun, M. A., Jørgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaløy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, A., Lobbens, S., Loh, M., Lorentzon, M., Luben, R. N., Lubke, G., Ludolph-donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-Vidal, P., Martin, N. G., McKenzie, C. A., McKnight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-Torvik, L. J., Rawal, R., Rice, T. K., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M-C., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S. H., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Chen, Y., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., de Faire, U., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-Larsen, P., Grabe, H-J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Wouter Jukema, J., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Marchand, L. L., März, W., McCarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, O., Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sørensen, T. I. A., Strauch, K., Tiemeier, H., Tremoli, E., van der Harst, P., Vestergaard, H., Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J. L., Loos, R. J. F., Kilpeläinen, T. O., Liu, C-T., Borecki, I. B., North, K. E. & Cupples, L. A., 26 Apr 2017, In: Nature Communications. 8, 19 p., 14977.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        111 Citations (Scopus)
        151 Downloads (Pure)

      • Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with Major Depressive Disorder

        Yanni, Z., Navarro, P., Shirali, M., Howard, D. M., Adams, M. J., Hall, L. S., Clarke, T-K., Thomson, P. A., Smith, B. H., Murray, A., Padmanabhan, S., Hayward, C., Boutin, T., MacIntyre, D. J., Lewis, C. M., Wray, N. R., Mehta, D., Penninx, B. W. J. H., Milaneschi, Y., Baune, B. T., & 20 othersAir, T., Hottenga, J-J., Mbarek, H., Castelao, E., Pistis, G., Schulze, T. G., Streit, F., Forstner, A. J., Byrne, E. M., Martin, N. G., Breen, G., Müller-Myhsok, B., Lucae, S., Kloiber, S., Domenici, E., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Deary, I. J., Porteous, D. J., Haley, C. S. & McIntosh, A. M., 1 Sept 2017, In: Biological Psychiatry. 82, 5, p. 312-321 10 p.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        19 Citations (Scopus)
        140 Downloads (Pure)

      • Has primary care antimicrobial use really been increasing? Comparison of changes in different prescribing measures for a complete geographic population 1995-2014

        Neilly, M. D. J., Guthrie, B., Hernandez Santiago, V., Vadiveloo, T., Donnan, P. T. & Marwick, C. A., 1 Oct 2017, In: Journal of Antimicrobial Chemotherapy. 72, 10, p. 2921-2930 10 p.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        10 Citations (Scopus)
        189 Downloads (Pure)

      • Investigating shared aetiology between type 2 diabetes and major depressive disorder in a population based cohort

        Clarke, T-K., Obsteter, J., Hall, L. S., Hayward, C., Thomson, P. A., Smith, B. H., Padmanabhan, S., Hocking, L. J., Deary, I. J., Porteous, D. J. & McIntosh, A. M., Apr 2017, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 174, 3, p. 227-234 8 p.

        Research output: Contribution to journal › Review article › peer-review

        Open Access
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        19 Citations (Scopus)
        155 Downloads (Pure)

      • Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

        Christophersen, I. E., Rienstra, M., Roselli, C., Yin, X., Geelhoed, B., Barnard, J., Lin, H., Arking, D. E., Smith, A. V., Albert, C. M., Chaffin, M., Tucker, N. R., Li, M., Klarin, D., Bihlmeyer, N. A., Low, S-K., Weeke, P. E., Mueller-Nurasyid, M., Smith, J. G., Brody, J. A., & 142 othersNiemeijer, M. N., Doerr, M., Trompet, S., Huffman, J. E., Gustafsson, S., Schurmann, C., Kleber, M. E., Lyytikainen, L-P., Seppala, I., Malik, R., Horimoto, A. R. V. R., Perez, M., Sinisalo, J., Aeschbacher, S., Theriault, S., Yao, J., Radmanesh, F., Weiss, S., Teumer, A., Choi, S. H., Weng, L-C., Clauss, S., Deo, R., Rader, D. J., Shah, S. H., Sun, A., Hopewell, J. C., Debette, S., Chauhan, G., Yang, Q., Worrall, B. B., Pare, G., Kamatani, Y., Hagemeijer, Y. P., Verweij, N., Siland, J. E., Kubo, M., Smith, J. D., Van Wagoner, D. R., Bis, J. C., Perz, S., Psaty, B. M., Ridker, P. M., Magnani, J. W., Harris, T. B., Launer, L. J., Shoemaker, M. B., Padmanabhan, S., Haessler, J., Bartz, T. M., Waldenberger, M., Lichtner, P., Arendt, M., Krieger, J. E., Kahonen, M., Risch, L., Mansur, A. J., Peters, A., Smith, B. H., Lind, L., Scott, S. A., Lu, Y., Bottinger, E. B., Hernesniemi, J., Lindgren, C. M., Wong, J. A., Huang, J., Eskola, M., Morris, A. P., Ford, I., Reiner, A. P., Delgado, G., Chen, L. Y., Chen, Y-D. I., Sandhu, R. K., Li, M., Boerwinkle, E., Eisele, L., Lannfelt, L., Rost, N., Anderson, C. D., Taylor, K. D., Campbell, A., Magnusson, P. K. E., Porteous, D. J., Hocking, L. J., Vlachopoulou, E., Pedersen, N. L., Nikus, K., Orho-Melander, M., Hamsten, A., Heeringa, J., Denny, J. C., Kriebel, J., Darbar, D., Newton-Cheh, C., Shaffer, C. M., Macfarlane, P. W., Heilmann-Heimbach, S., Almgren, P., Huang, P. L., Sotoodehnia, N., Soliman, E. Z., Uitterlinden, A. G., Hofman, A., Franco, O. H., Voelker, U., Joeckel, K-H., Sinner, M. F., Lin, H. J., Guo, X., Dichgans, M., Ingelsson, E., Kooperberg, C., Melander, O., Loos, R. J. F., Laurikka, J., Conen, D., Rosand, J., van der Harst, P., Lokki, M-L., Kathiresan, S., Pereira, A., Jukema, J. W., Hayward, C., Rotter, J. I., Maerz, W., Lehtimaki, T., Stricker, B. H. C., Chung, M. K., Felix, S. B., Gudnason, V., Alonso, A., Roden, D. M., Kaeaeb, S., Chasman, D. I., Heckbert, S. R., Benjamin, E. J., Tanaka, T., Lunetta, K. L., Lubitz, S. A. & Ellinor, P. T., Jun 2017, In: Nature Genetics. 49, 6, p. 946-952 7 p.

        Research output: Contribution to journal › Letter › peer-review

        Open Access
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        185 Citations (Scopus)
        331 Downloads (Pure)

      • Mapping Local Codes to Read Codes

        Bonney, W., Galloway, J., Hall, C., Ghattas, M., Tramma, L., Nind, T., Donnelly, L., Jefferson, E. & Doney, A., 2017, Building Capacity for Health Informatics in the Future. Lau, F., Bartle-Clar, J., Bliss, G., Borycki, E., Courtney, K. & Kuo, A. (eds.). Amsterdam: IOS Press, p. 29-36 8 p. (Studies in Health Technology and Informatics; vol. 234).

        Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

        Open Access
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        3 Citations (Scopus)
        284 Downloads (Pure)

      • Meta-analysis of genome-wide association studies on the intolerance of angiotensin-converting enzyme inhibitors

        Mahmoudpour, S. H., Veluchamy, A., Siddiqui, M. K., Asselbergs, F. W., Souverein, P. C., de Keyser, C. E., Hofman, A., Lang, C. C., Doney, A. S. F., Stricker, B. H., de Boer, A., Maitland-van der Zee, A-H., Palmer, C. N. A. & PREDICTION-ADR Consortium, Mar 2017, In: Pharmacogenetics and Genomics. 27, 3, p. 112-119 8 p.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        15 Citations (Scopus)
        146 Downloads (Pure)

      • Modifying Alcohol Consumption to Reduce Obesity: A Randomized Controlled Feasibility Study of a Complex Community-based Intervention for Men

        Irvine, L., Crombie, I., Cunningham, K., Williams, B., Sniehotta, F. F., Norrie, J., Melson, A., Jones, C., Rice, P., Slane, P. W., Achison, M., McKenzie, A., Dimova, E. & Allan, S., 1 Nov 2017, In: Alcohol and Alcoholism. 52, 6, p. 677-684 9 p.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        7 Citations (Scopus)
        131 Downloads (Pure)

      • Oral and topical antibiotics for clinically infected eczema in children: a pragmatic randomized controlled trial in ambulatory care

        Francis, N. A., Ridd, M. J., Thomas-Jones, E., Butler, C. C., Hood, K., Shepherd, V., Marwick, C. A., Huang, C., Longo, M., Wootton, M., Sullivan, F. & the CREAM Trial Management Group, 30 Apr 2017, In: Annals of Family Medicine. 15, 2, p. 124-130 7 p.

        Research output: Contribution to journal › Article › peer-review

        29 Citations (Scopus)

      • Prevalence of unrecognised myocardial infarction in a low-intermediate risk asymptomatic cohort and its relation to systemic atherosclerosis

        Weir-McCall, J., Papagiorcopulo, C. J., Fitzgerald, K., Gandy, S., Lambert, M., Belch, J., Cavin, I., Littleford, R., MacFarlance, J. A., Matthew, S., Nicholas, R. S., Struthers, A., Sullivan, F., Waugh, S. A., White, R. D. & Houston, J., Jun 2017, In: European Heart Journal - Cardiovascular Imaging. 18, 6, p. 657-662 6 p.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        13 Citations (Scopus)
        105 Downloads (Pure)

      • Process evaluation of the Data-driven Quality Improvement in Primary Care (DQIP) trial: case-study evaluation of adoption and maintenance of a complex intervention to reduce high-risk primary care prescribing

        Grant, A., Dreischulte, T. & Guthrie, B., 1 Mar 2017, In: BMJ Open. 7, 3, p. 1-12 12 p., e015281.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        17 Citations (Scopus)
        167 Downloads (Pure)

      • Rates of glycaemic deterioration in a real-world population with type 2 diabetes

        Donnelly, L. A., Zhou, K., Doney, A. S. F., Jennison, C., Franks, P. W. & Pearson, E. R., 19 Dec 2017, In: Diabetologia. 61, p. 607-615 9 p.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        31 Citations (Scopus)
        193 Downloads (Pure)

      • Real Time Monitoring of Engagement with a Text Message Intervention to Reduce Binge Drinking Among Men Living in Socially Disadvantaged Areas of Scotland

        Irvine, L., Melson, A. J., Williams, B., Sniehotta, F. F., McKenzie, A., Jones, C. & Crombie, I. K., Oct 2017, In: International Journal of Behavioral Medicine. 24, 5, p. 713-721 9 p.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        9 Citations (Scopus)
        168 Downloads (Pure)

      • Regional variation in health is predominantly driven by lifestyle rather than genetics

        Amador, C., Xia, C., Nagy, R., Campbell, A., Porteous, D. J., Smith, B. H., Hastie, N., Vitart, V., Hayward, C., Navarro, P. & Haley, C. S., 6 Oct 2017, In: Nature Communications. 8, p. 1-7 7 p., 801.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        9 Citations (Scopus)
        158 Downloads (Pure)

      • Replication confirms the association of loci in FOXE1, PDE8B, CAPZB and PDE10A with thyroid traits: a Genetics of Diabetes Audit and Research Tayside study

        Soto-Pedre, E., Siddiqui, M. K., Doney, A. S., Palmer, C. N. A., Pearson, E. R. & Leese, G. P., 1 Oct 2017, In: Pharmacogenetics and Genomics. 27, 10, p. 356-362 7 p.

        Research output: Contribution to journal › Article › peer-review

        Open Access
        File
        6 Citations (Scopus)
        278 Downloads (Pure)

      • Risk of acute kidney injury and survival in patients treated with Metformin: an observational cohort study

        Bell, S., Farran, B., McGurnaghan, S., McCrimmon, R., Leese, G. P., Petrie, J. R., McKeigue, P. M., Sattar, N., Wild, S., McKnight, J., Lindsay, R., Colhoun, H. M. & Looker, H., 19 May 2017, In: BMC Nephrology. 18, p. 1-8 8 p., 163.

        Research output: Contribution to journal › Article › peer-review

        Open Access
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        43 Citations (Scopus)
        162 Downloads (Pure)

      • Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

        Jason, F., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F., & 281 othersHighland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B-J., Kim, Y., Kim, Y. J., Kwon, M-S., Lee, J., Lee, S., Lin, K-H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B-G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S-H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C-Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C-C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S-T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., de Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A-C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J-Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Scott, L. J., Morris, A. P., Kang, H. M., Altshuler, D., Burtt, N. P., Florez, J. C., Boehnke, M. & McCarthy, M. I., 19 Dec 2017, In: Scientific Data. 4, p. 1-20 20 p., 170179.

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      • Temporal changes in frequency of severe hypoglycemia treated by emergency medical services in types 1 and 2 diabetes: a population-based data-linkage cohort study

        Wang, H., Donnan, P. T., Leese, C. J., Duncan, E., Fitzpatrick, D. R., Frier, B. M. & Leese, G. P., 15 Aug 2017, In: Clinical Diabetes and Endocrinology. 3, p. 1-8 8 p., 7.

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      • The epidemiology of hyperprolactinaemia over 20 years in the Tayside region of Scotland: The Prolactin Epidemiology, Audit, and Research Study (PROLEARS)

        Soto-Pedre, E., Newey, P. J., Bevan, J. S., Greig, N. & Leese, G. P., Jan 2017, In: Clinical Endocrinology. 86, 1, p. 60-67 8 p.

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        33 Citations (Scopus)
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      • The genetic landscape of renal complications in type 1 diabetes

        Sandholm, N., Van Zuydam, N., Ahlqvist, E., Juliusdottir, T., Deshmukh, H. A., Rayner, N. W., Di Camillo, B., Forsblom, C., Fadista, J., Ziemek, D., Salem, R. M., Hiraki, L. T., Pezzolesi, M., Trégouët, D., Dahlström, E., Valo, E., Oskolkov, N., Ladenvall, C., Marcovecchio, M. L., Cooper, J., & 31 othersSambo, F., Malovini, A., Manfrini, M., McKnight, A. J., Lajer, M., Harjutsalo, V., Gordin, D., Parkkonen, M., The FinnDiane Study Group, Tuomilehto, J., Lyssenko, V., McKeigue, P. M., Rich, S. S., Brosnan, M. J., Fauman, E., Bellazzi, R., Rossing, P., Krolewski, A., Paterson, A. D., The DCCT/EDIC Study Group, Florez, J. C., Hirschhorn, J. N., Maxwell, A. P., GENIE Consortium, Dunger, D., Cobelli, C., Colhoun, H. M., Groop, L., McCarthy, M. I., Groop, P-H. & SUMMIT Consortium, Feb 2017, In: Journal of the American Society of Nephrology. 28, 2, p. 557-574 18 p.

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        75 Citations (Scopus)
      • 2016

        Accounting for multimorbidity in pay for performance: a modelling study using UK Quality and Outcomes Framework data

        Ruscitto, A., Mercer, S. W., Morales, D. & Guthrie, B., 5 Jul 2016, In: British Journal of General Practice. 66, 649, p. e561-e567 7 p.

        Research output: Contribution to journal › Article › peer-review

        3 Citations (Scopus)

      • Adherence to antiepileptic drugs in children with epilepsy in a Scottish population cohort

        Shetty, J., Greene, S. A., Mesalles-Naranjo, O. & Kirkpatrick, M., May 2016, In: Developmental Medicine and Child Neurology. 58, 5, p. 469-474 6 p.

        Research output: Contribution to journal › Article › peer-review

        18 Citations (Scopus)

      • A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

        Mosley, J. D., Shaffer, C. M., Van Driest, S. L., Weeke, P. E., Wells, Q. S., Karnes, J. H., Velez Edwards, D. R., Wei, W-Q., Teixeira, P. L., Bastarache, L., Crawford, D. C., Li, R., Manolio, T. A., Bottinger, E. P., McCarty, C. A., Linneman, J. G., Brilliant, M. H., Pacheco, J. A., Thompson, W., Chisholm, R. L., & 27 othersJarvik, G. P., Crosslin, D. R., Carrell, D. S., Baldwin, E., Ralston, J., Larson, E. B., Grafton, J., Scrol, A., Jouni, H., Kullo, I. J., Tromp, G., Borthwick, K. M., Kuivaniemi, H., Carey, D. J., Ritchie, M. D., Bradford, Y., Verma, S. S., Chute, C. G., Veluchamy, A., Siddiqui, M., Palmer, C. N. A., Doney, A., MahmoudPour, S. H., Maitland-van der Zee, A. H., Morris, A. D., Denny, J. C. & Roden, D. M., Jun 2016, In: Pharmacogenomics Journal. 16, 3, p. 231-237 7 p.

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      • A Genome-Wide Association Study Provides New Evidence That CACNA1C Gene is Associated With Diabetic Cataract

        Chang, C., Zhang, K., Veluchamy, A., Hébert, H. L., Looker, H. C., Colhoun, H. M., Palmer, C. N. A. & Meng, W., 1 Apr 2016, In: Investigative Ophthalmology & Visual Science. 57, 4, p. 2246-50 5 p.

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        11 Citations (Scopus)
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      • An evaluation of the psychometric properties of the Indicator of Relative Need (IoRN) instrument

        Canny, A., Robertson, F., Knight, P., Redpath, A. & Witham, M. D., 28 Jul 2016, In: BMC Geriatrics. 16, 10 p., 147.

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      • Association between allopurinol use and hip fracture in older patients

        Basu, U., Goodbrand, J., McMurdo, M. E. T., Donnan, P. T., McGilchrist, M., Frost, H., George, J. & Witham, M. D., Mar 2016, In: Bone. 84, p. 189-193 5 p.

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        12 Citations (Scopus)
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      • Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

        Gonçalves, I., Edsfeldt, A., Colhoun, H. M., Shore, A. C., Palombo, C., Natali, A., Fredrikson, G. N., Björkbacka, H., Wigren, M., Bengtsson, E., Östling, G., Aizawa, K., Casanova, F., Persson, M., Gooding, K., Gates, P., Khan, F., Looker, H. C., Adams, F., Belch, J., & 7 othersPinnola, S., Venturi, E., Kozakova, M., Gan, L-M., Schnecke, V., Nilsson, J. & SUMMIT Consortium, 5 Sept 2016, In: BMC Cardiovascular Disorders. 16, p. 1-10 10 p., 171.

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        11 Citations (Scopus)
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      • A systems BIOlogy Study to TAilored Treatment in Chronic Heart Failure: Rationale, design, and baseline characteristics of BIOSTAT-CHF

        Voors, A. A., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., ter Maaten, J. M., Ng, L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H. & Metra, M., 20 Jun 2016, In: European Journal of Heart Failure. 18, 6, p. 716-726 11 p.

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        127 Citations (Scopus)

      • Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease

        Stitziel, N. O., Stirrups, K. E., Masca, N. G. D., Erdmann, J., Ferrario, P. G., König, I. R., Weeke, P. E., Webb, T. R., Auer, P. L., Schick, U. M., Lu, Y., Zhang, H., Dube, M. P., Goel, A., Farrall, M., Peloso, G. M., Won, H. H., Do, R., Van Iperen, E., Kanoni, S., & 109 othersKruppa, J., Mahajan, A., Scott, R. A., Willenborg, C., Braund, P. S., Van Capelleveen, J. C., Doney, A. S. F., Donnelly, L. A., Asselta, R., Merlini, P. A., Duga, S., Marziliano, N., Denny, J. C., Shaffer, C. M., El-Mokhtari, N. E., Franke, A., Gottesman, O., Heilmann, S., Hengstenberg, C., Hoffmann, P., Holmen, O. L., Hveem, K., Jansson, J. H., Jöckel, K. H., Kessler, T., Kriebel, J., Laugwitz, K. L., Marouli, E., Martinelli, N., McCarthy, M. I., van Zuydam, N. R., Meisinger, C., Esko, T., Mihailov, E., Escher, S. A., Alver, M., Moebus, S., Morris, A. D., Müller-Nurasyid, M., Nikpay, M., Olivieri, O., Perreault, L. P. L., AlQarawi, A., Robertson, N. R., Akinsanya, K. O., Reilly, D. F., Vogt, T. F., Yin, W., Asselbergs, F. W., Kooperberg, C., Jackson, R. D., Stahl, E., Strauch, K., Varga, T. V., Waldenberger, M., Zeng, L., Kraja, A. T., Liu, C., Ehret, G. B., Newton-Cheh, C., Chasman, D. I., Chowdhury, R., Ferrario, M., Ford, I., Jukema, J. W., Kee, F., Kuulasmaa, K., Nordestgaard, B. G., Perola, M., Saleheen, D., Sattar, N., Surendran, P., Tregouet, D., Young, R., Howson, J. M. M., Butterworth, A. S., Danesh, J., Ardissino, D., Bottinger, E. P., Erbel, R., Franks, P. W., Girelli, D., Hall, A. S., Hovingh, G. K., Kastrati, A., Lieb, W., Meitinger, T., Kraus, W. E., Shah, S. H., McPherson, R., Orho-Melander, M., Melander, O., Metspalu, A., Palmer, C. N. A., Peters, A., Rader, D. J., Reilly, M. P., Loos, R. J. F., Reiner, A. P., Roden, D. M., Tardif, J. C., Thompson, J. R., Wareham, N. J., Watkins, H., Willer, C. J., Kathiresan, S., Deloukas, P., Samani, N. J. & Schunkert, H., 24 Mar 2016, In: New England Journal of Medicine. 374, 12, p. 1134-1144 11 p.

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      • CYP2C8 and SLCO1B1 variants and therapeutic response to thiazolidinediones in patients with type 2 diabetes.

        Dawed, A. Y., Donnelly, L., Tavendale, R., Carr, F., Leese, G., Palmer, C. N. A., Pearson, E. & Zhou, K., Nov 2016, In: Diabetes Care. 39, 11, p. 1902-1908 7 p.

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        44 Citations (Scopus)
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      • Fair access to medicine? Retrospective analysis of UK medical schools application data 2009-2012 using three measures of socioeconomic status

        Steven, K., Dowell, J., Jackson, C. & Guthrie, B., 13 Jan 2016, In: BMC Medical Education. 16, 1, 10 p., 11.

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        67 Citations (Scopus)
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      • Genetic variants linked to education predict longevity

        22 Nov 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 47, p. 13366-13371 6 p.

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        45 Citations (Scopus)
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      • How does sex influence multimorbidity? Secondary analysis of a large nationally representative dataset

        Agur, K., McLean, G., Hunt, K., Guthrie, B. & Mercer, S. W., Apr 2016, In: International Journal of Environmental Research and Public Health. 13, 4, 12 p., 391.

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        31 Citations (Scopus)
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      • Incidence and outcomes of Acute Kidney Injury requiring renal replacement therapy: a retrospective cohort study

        Rennie, T. J. W., Patton, A., Dreischulte, T. & Bell, S., Aug 2016, In: Nephron. 133, 4, p. 239-246 8 p.

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        11 Citations (Scopus)
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      • Mean HbA1c and mortality in diabetic individuals with heart failure: a population cohort study

        Elder, D. H. J., Singh, J. S. S., Levin, D., Donnelly, L. A., Choy, A-M. J., George, J., Struthers, A. D., Doney, A. S. F. & Lang, C. C., Jan 2016, In: European Journal of Heart Failure. 18, 1, p. 94-102 9 p.

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      • Predictors of quality of life in head and neck cancer survivors up to 5 years after end of treatment: a cross-sectional survey

        Wells, M., Swartzman, S., Lang, H., Cunningham, M., Taylor, L., Thomson, J., Philp, J. & McCowan, C., Jun 2016, In: Supportive Care in Cancer. 24, 6, p. 2463-2472 10 p.

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        42 Citations (Scopus)

      • Reduction in post-operative acute kidney injury following a change in antibiotic prophylaxis policy for orthopaedic surgery: an observational study

        Walker, H., Patton, A., Bayne, G., Marwick, C., Sneddon, J., Davey, P., Nathwani, D. & Bell, S., Sept 2016, In: Journal of Antimicrobial Chemotherapy. 71, 9, p. 2598-2605 8 p.

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      • Safer Prescribing: A Trial of Education, Informatics, and Financial Incentives

        Dreischulte, T., Donnan, P., Grant, A., Hapca, A., McCowan, C. & Guthrie, B., 17 Mar 2016, In: New England Journal of Medicine. 374, 11, p. 1053-1064 12 p.

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      • Slower Decline in C-Reactive Protein after an Inflammatory Insult Is Associated with Longer Survival in Older Hospitalised Patients

        Barma, M., Goodbrand, J. A., Donnan, P. T., McGilchrist, M. M., Frost, H., McMurdo, M. E. T. & Witham, M. D., 28 Jul 2016, In: PLoS ONE. 11, 7, 10 p., e0159412.

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        4 Citations (Scopus)
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      • Targeting, monitoring and effect of oral iron therapy on haemoglobin levels in older patients discharged to primary care from inpatient rehabilitation: a cohort study using routinely collected data

        Thomson, Z., Hands, K. J. & Witham, M., Aug 2016, In: Drugs & Aging. 33, 8, p. 603-610 8 p.

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      • The genetic architecture of type 2 diabetes

        Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F., Highland, H. M., & 281 othersDupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B-J., Kim, Y., Kim, Y. J., Kwon, M-S., Lee, J., Lee, S., Lin, K-H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B-G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S-H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C-Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C-C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., van der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S-T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., Hrabé de Angelis, M., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A-C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J-Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M., Altshuler, D. & McCarthy, M. I., 4 Aug 2016, In: Nature. 536, p. 41-47 29 p., 18642.

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      • The health and economic burden of bloodstream infections caused by antimicrobial-susceptible and non-susceptible Enterobacteriaceae and Staphylococcus aureus in European hospitals, 2010 and 2011: a multicentre retrospective cohort study

        Stewardson, A. J., Allignol, A., Beyersmann, J., Graves, N., Schumacher, M., Meyer, R., Tacconelli, E., De Angelis, G., Farina, C., Pezzoli, F., Bertrand, X., Gbaguidi-Haore, H., Edgeworth, J., Tosas, O., Martinez, J. A., Ayala-Blanco, M. P., Pan, A., Zoncada, A., Marwick, C. A., Nathwani, D., & 6 othersSeifert, H., Hos, N., Hagel, S., Pletz, M., Harbarth, S. & TIMBER Study Group, 18 Aug 2016, In: Eurosurveillance. 21, 33, p. 1-12 12 p., Article 2.

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      • 2015

        A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain

        Meng, W., Deshmukh, H. A., Donnelly, L. A., Wellcome Trust Case Control Consortium 2, Surrogate Markers for Micro- and Macro-Vascular Hard Endpoints for Innovative Diabetes Tools (SUMMIT) Study Group, Torrance, N., Colhoun, H. M., Palmer, C. N. A. & Smith, B. H., Oct 2015, In: EBioMedicine. 2, 10, p. 1386-1393 8 p.

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        50 Citations (Scopus)
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      • Analysis of hyponatraemia associated post-operative mortality in 3897 hip fracture patients

        Tinning, C. G., Cochrane, L. A. & Singer, B. R., 1 Jul 2015, In: Injury: the British Journal of Accident Surgery. 46, 7, p. 1328-1332 5 p.

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        18 Citations (Scopus)

      • Assessment of spirometry and impulse oscillometry in relation to asthma control

        Manoharan, A., Anderson, W. J., Lipworth, J. & Lipworth, B. J., Feb 2015, In: Lung. 193, 1, p. 47-51 5 p.

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        32 Citations (Scopus)

      • Association between kidney function, rehabilitation outcome, and survival in older patients discharged from inpatient rehabilitation

        Doyle, E. M., Sloan, J. M., Goodbrand, J. A., McMurdo, M. E. T., Donnan, P. T., McGilchrist, M. M., Frost, H. & Witham, M. D., Nov 2015, In: American Journal of Kidney Diseases. 66, 5, p. 768-774 7 p.

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      • Association between retinal vasculature and muscle mass in older people

        Sumukadas, D., McMurdo, M., Pieretti, I., Ballerini, L., Price, R., Wilson, P., Doney, A., Leese, G. & Trucco, E., Nov 2015, In: Archives of Gerontology and Geriatrics. 61, 3, p. 425-428 4 p.

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        4 Citations (Scopus)