Keyphrases
Leucine-rich Repeat Kinase 2 (LRRK2)
61%
Ubiquitylation
40%
E3 Ligase
36%
Ubiquitin
36%
Parkin
32%
Parkinson's Disease
28%
Proteolysis Targeting chimera (PROTAC)
26%
E3 Ubiquitin Ligase
23%
UFM1
23%
Phosphorylation
21%
Budding Yeast
19%
TORC1
19%
Mitophagy
17%
Protein Phosphorylation
17%
Degrader
16%
Endoplasmic Reticulum
16%
Ubiquitin Ligase Activity
15%
High-throughput
15%
Rnf12
15%
CMG Helicase
15%
Autophosphorylation
15%
Assembly Chaperone
15%
VPS35
15%
PTEN-induced Kinase 1 (PINK1)
15%
Phosphatase
14%
UFMylation
14%
HOIL-1L
13%
Matrix-assisted Laser Desorption Ionization-time of Flight Mass Spectrometry (MALDI-TOF MS)
13%
RNA Polymerase II (RNAPII)
12%
Helicase
12%
Mitochondria
11%
Eukaryotes
11%
Proteasome Assembly
11%
Dephosphorylation
11%
Drug Discovery
10%
Protein Function
10%
Catalytic Subunit
10%
Replisome
10%
Cdc48
9%
Golgi
9%
Non-canonical
9%
E3 Ligase Activity
9%
UBE2T
9%
Primary Neurons
9%
Parkinson
9%
Protein Phosphatase 2A (PP2A)
9%
Phosphoproteomics
9%
Rab29
9%
Outer Membrane Complex
9%
Ciliogenesis
9%
Mass Spectrometry Analysis
8%
Activating mutation
8%
Fibrosis
8%
Esters
8%
Protease Inhibitors
8%
TORC1 Signaling
8%
Proteomics Data
8%
Protein Phosphatase
8%
Chromatin
8%
Multisite Phosphorylation
8%
60S Ribosomal Subunit
8%
Membrane Recruitment
8%
Membrane Activation
8%
Threonine
8%
Activation Mechanism
8%
Phospholipids
8%
UBE2A
7%
UBE2B
7%
PPP2CA
7%
Regulation Mechanism
7%
UBR4
7%
GTPase
7%
Embryonic Gene Expression
7%
Syrbactin
7%
Immunoproteasome Inhibitor
7%
Spt5
7%
Constitutive Proteasome
7%
ROSAH Syndrome
7%
MALDI-TOF Mass Spectrometry
7%
Polyglucosan
7%
Reconstituted System
7%
STK33
7%
Deubiquitinating Enzyme
7%
NPL4
7%
KLHDC2
7%
Deubiquitinase
7%
Protein Ubiquitylation
7%
Multimodal Analysis
7%
SHP-1
7%
ARID1A
7%
Rab12
7%
Polyubiquitin
7%
Bleomycin-induced Lung Injury
7%
Genetic Screening
7%
Structure-based Design
7%
Cellular Stress
7%
BNIP3L
7%
Enzyme Assay
7%
Activity-based Probes
7%
TMEM55B
7%
Ribosome-associated Chaperones
7%
Target Following
7%
Conserved Mechanisms
7%
NEK1
7%
Berzosertib
7%
ATR Inhibitor
7%
MCM7
7%
Two-pathway
7%
Heme-regulated Inhibitor
7%
Heme Binding
7%
GTPase Domain
7%
Transcriptional Repression
7%
Mammalian Cell Cycle
7%
Penetrant
7%
Homeostasis
7%
Stem Cells
7%
ERK5
7%
Ufd1
7%
Forkhead Box P3 (FOXP3)
7%
Rejuvenation
7%
X Chromosome Inactivation
7%
Particle Assembly
7%
Bisphosphonates
7%
SWItch/Sucrose Non-fermentable
7%
Catenin
7%
Myeloma
7%
Protein Localization
7%
Kruppel-like Factor 2 (KLF2)
7%
Pexophagy
7%
Bone Degeneration
7%
Toll-like Receptor 7 (TLR7)
7%
Protein Kinase C Isoforms
7%
DONSON
7%
Co-immunoprecipitation (co-IP)
7%
Transcriptional Activation
7%
K-ras
7%
Signaling Modules
7%
Protein Stability
7%
Target Molecule
7%
Severe Disease
7%
Histone Binding
7%
Metabolic Rewiring
7%
Early Embryo
7%
Functional Characterization
7%
Ubiquitin Linkage
7%
N-terminal Helix
7%
Actin Remodeling
7%
Missense Variants
7%
Telomere
7%
Binding Activity
7%
Orally Bioavailable
7%
Diaphragmatic Hernia
7%
C-terminal Extension
7%
DGAT1
7%
Mutation Carriers
7%
Protease
7%
Unfoldase
7%
Ester Bond
7%
Conserved Residues
7%
SIK2
7%
IRAK2
7%
Blood-brain Barrier
7%
Translocon
7%
Palmoplantar Keratoderma
7%
ALPK1
7%
HTTPS
7%
Web Tool
7%
Response Regulator
7%
DNA Damage Response
7%
New Biomarkers
7%
FAM83G
7%
Structural Rearrangement
7%
Nucleotide Sugars
7%
RILPL1
7%
Wnt Signaling
7%
Spiradenoma
7%
Feed-forward Mechanism
7%
Neuroprotective
7%
Smad3
7%
Transforming Growth Factor-β
7%
Growth Factor Signaling
7%
WRN Helicase
7%
Selective Killing
7%
Cancer Cells
7%
Microsatellite Instability-high (MSI-H)
7%
Mouse Embryonic Stem Cells (mESCs)
7%
Zinc Finger
6%
Kinase Domain
6%
Protein of Interest
6%
Clinical Trials
6%
Cell Viability
6%
CDC45
6%
Human Disease
6%
Actin Patch
5%
Regulatory Particle
5%
Cortical Actin
5%
Sigma Phase
5%
Knock-in Mouse Model
5%
Protein Kinase
5%
AlphaFold
5%
Biochemistry, Genetics and Molecular Biology
Kinase
100%
Phosphotransferase
100%
Ubiquitin
65%
Leucine-Rich Repeat
49%
Ubiquitin Ligase
45%
Ubiquitination
39%
Proteolysis
29%
Proteasome
26%
Ubiquitin-Conjugating Enzyme
25%
Mass Spectrometry
25%
Helicase
25%
Phosphatase
24%
PINK1
23%
Transcription
22%
LRRK2
21%
Mitophagy
20%
Budding Yeast
20%
Proteomics
19%
Enzyme
19%
GTPase
16%
Enzyme Active Site
15%
P97
15%
VPS35
15%
Gene Linkage
15%
Autophosphorylation
15%
Cancer Cell
15%
Mitochondrion
12%
Embryonic Stem Cell
12%
Binding Site
12%
N-Terminus
12%
Cell Cycle
12%
Phosphoprotein Phosphatase
11%
Ciliogenesis
11%
Dephosphorylation
11%
Protein Kinases
11%
Quality Control
10%
Replisome
10%
Drive
10%
Eukaryote
10%
Phospholipid
10%
Fibroblast
10%
Homeostasis
10%
Protein Homeostasis
9%
Proteasome Inhibitor
9%
C-Terminus
9%
Genetics
9%
Stem Cell
9%
Actin
8%
Clinical Trial
8%
DNA Synthesis
8%
Lysosome
8%
Cell Viability
8%
Binding Affinity
8%
Small Molecule
8%
Translocase
8%
Transfer RNA
7%
Lysine
7%
Translocon
7%
Lipid
7%
Protein Dephosphorylation
7%
RING1
7%
Matrix-Assisted Laser Desorption-Ionization
7%
Isoform
7%
Protein Stability
7%
ARID1A
7%
X-Inactivation
7%
Missense
7%
RNA Polymerase II
7%
Actin Remodeling
7%
Enzyme Assay
7%
Catenin
7%
Maturation
7%
KLF2
7%
Cell Stress
7%
Pexophagy
7%
BNIP3L
7%
Intravenous Immunoglobulin
7%
Gene Expression
7%
Immunoprecipitation
7%
Protein Kinase C
7%
Blood Brain Barrier
7%
TLR7
7%
DNA Damage
7%
DNA Damage Response
7%
Phosphoproteomics
7%
Exome Sequencing
7%
SWI/SNF
7%
Protease
7%
Histone
7%
Heptose
7%
Adenosine Diphosphate
7%
Nucleotide Sugar
7%
Cancer Growth Factor
7%
Microsatellite Instability
7%
Deubiquitylating Enzyme
7%
Growth Factor Signaling
7%
Telomere
7%
Enzyme Specificity
7%
Serine
6%
Threonine
6%
Autophagy
6%
Adenosine Triphosphate
6%
Uridine Diphosphate
6%
S Phase
6%
Metabolome
5%
Crystal Structure
5%
Nucleosome
5%
Matrix-Assisted Laser Desorption/Ionization
5%
Time-of-Flight Mass Spectrometry
5%
Cryoelectron Microscopy
5%
Single-Domain Antibody
5%
RNA Binding
5%
Protein Catabolism
5%
Protein Biosynthesis
5%