Research output per year
Research output per year
Equipments Details
Description
Crystallography is the most powerful method for determining the atomic three-dimensional structures of large biological molecules. The technique provides valuable information used to direct research projects throughout the School, where groups use X-ray crystallography to link protein structure with function, to aid in rational drug design and perform fragment screening.
Publication mapping for SLS facilities in Discovery began in 2021 and so does not include the historical contributions of the facilities in research across the University.
Publication mapping for SLS facilities in Discovery began in 2021 and so does not include the historical contributions of the facilities in research across the University.
Fingerprint
Explore the research areas in which this equipment has been used. These labels are generated based on the related outputs. Together they form a unique fingerprint.
Research output
- 2 Article
-
Design and development of lysyl tRNA synthetase inhibitors, for the treatment of tuberculosis
Davis, S. H., Mathieson, M., Buchanan, K. I., Dawson, A., Smith, A., Cocco, M., Tamaki, F. K., Post, J. M., Baragaña, B., Jansen, C., Kiczun, M., Zuccotto, F., Wood, G., Scullion, P., Ray, P. C., Epemolu, O., Lopez-Román, E. M., Guijarro López, L., Engelhart, C. A. & Kim, J. & 8 others, , 14 Aug 2025, In: Journal of Medicinal Chemistry. 68, 15, p. 16459-16482 24 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)139 Downloads (Pure) -
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity
Green, S. R. (Lead / Corresponding author), Wilson, C., Eadsforth, T. C., Punekar, A. S., Tamaki, F. K., Wood, G., Caldwell, N., Forte, B., Norcross, N. R., Kiczun, M., Post, J. M., Lopez-Román, E. M., Engelhart, C. A., Lukac, I., Zuccotto, F., Epemolu, O., Boshoff, H. I. M., Schnappinger, D., Walpole, C. & Gilbert, I. H. & 3 others, , 23 Nov 2023, In: Journal of Medicinal Chemistry. 66, 22, p. 15380-15408 29 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Link opens in a new tab Citations (Scopus)413 Downloads (Pure)