Biological Chemistry and Drug Discovery

  • United Kingdom

Fingerprint Dive into the research topics where Biological Chemistry and Drug Discovery is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Trypanosoma brucei brucei Medicine & Life Sciences
Parasites Medicine & Life Sciences
Trypanosomiasis Medicine & Life Sciences
Proteins Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Drug Discovery Medicine & Life Sciences
Enzymes Medicine & Life Sciences
African Trypanosomiasis Medicine & Life Sciences

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Profiles

No photo of Eleanor Adams

Adams, Eleanor

Person: Research Postgraduate Student

No photo of Ross Bacchetti

Bacchetti, Ross

Person: Research Postgraduate Student

No photo of Gemma Baillie

Baillie, Gemma

Person: Associate Staff

20172017

Projects 2012 2025

Research Output 1972 2020

1 Citation (Scopus)
71 Downloads (Pure)

A chemical-genetics approach to study the role of atypical Protein Kinase C in Drosophila

Hannaford, M., Loyer, N., Tonelli, F., Zoltner, M. & Januschke, J., 29 Jan 2019, In : Development. 146, 2, p. 1-11 11 p., dev170589.

Research output: Contribution to journalArticle

Open Access
File
Drosophila
Phosphotransferases
Drosophila Proteins
Cell Polarity
Nuclear Envelope
34 Downloads (Pure)

A high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans-splicing

Pandarakalam, G. C., Speake, M., McElroy, S., Alturkistani, A., Philippe, L., Pettitt, J., Müller, B. & Connolly, B., Aug 2019, In : International Journal for Parasitology: Drugs and Drug Resistance. 10, p. 28-37 10 p.

Research output: Contribution to journalArticle

Open Access
File
Spliced Leader RNA
Trans-Splicing
Gene Targeting
Anthelmintics
Gene Expression

Amino acid substitutions in the human homomeric β3 GABAA receptor that enable activation by GABA

Gottschald Chiodi, C., Baptista-Hon, D., Hunter, W. & Hales, T., 15 Feb 2019, In : Journal of Biological Chemistry. 294, 7, p. 2375-2385 11 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Amino Acid Substitution
gamma-Aminobutyric Acid
Substitution reactions
Chemical activation

Datasets

Whole Genome Sequencing Variant Call Files for Trypanosoma brucei clones resistant to nifurtimox or fexinidazole

Fairlamb, A. (Creator), Foth, B. (Creator), Berriman, M. (Creator), University of Dundee, 2015

Dataset

File

Prizes

Awarded Capps Green Zomaya Award from the Royal Society of Chemistry

Andrew L. Hopkins (Recipient), 2008

Prize: Prize (including medals and awards)

Awarded Corwin Hansch Award, Chemoinformatics and QSAR Society

Andrew L. Hopkins (Recipient), 2007

Prize: Prize (including medals and awards)

Elected Fellow of the Learned Society of Wales

Andrew L. Hopkins (Recipient), 2014

Prize: Election to learned society

Activities 1997 2019

Science Saturday: Family Fun Day with Women in STEM Women's Festival Dundee

Christine Millar (Host), Heather Doran (Organiser), Rolf Black (Organiser), Amy Rogers (Organiser), Amy Cameron (Organiser), Catarina Sobreira (Contributor), Bethany Coull (Contributor), Daniella Cavellini (Contributor), Shobna Vasishta (Contributor), Amy Learmonth (Contributor), Simone Altmann (Contributor), Ruth Hamilton (Contributor), Carmen Escudero-Martinez (Contributor), Julie Kovarova (Contributor), Anna Trenaman (Contributor), Alice Dawson (Contributor), Nicola Morrice (Contributor)
2 Mar 2019

Activity: Other activity typesPublic engagement and outreach - festival/exhibition

File

Action Medical Research - Scientific Advisory Panel

David Gray (Member)
2019 → …

Activity: Other activity typesOther

Genetic evaluation of purine biosynthesis in Cryptosporidium parvum suggests nucleotide uptake from the host cell

Mattie Pawlowic (Speaker)
1 Nov 20182 Nov 2018

Activity: Talk or presentation typesInvited talk

Press / Media

Tuberculosis drug may also target visceral leishmaniasis

Alan H. Fairlamb & Kevin Read

24/05/16

1 item of Media coverage

Press/Media: Research

Automated design for Drug Discovery

Andrew L. Hopkins, Suzanne Norval, Jeremy Besnard, Laste Stojanovski, Richard Bickerton, Kevin Read & Ian Gilbert

13/12/12

1 item of Media coverage

Press/Media: Research

Student theses

A biophysical approach for the study of G-protein coupled receptor complexes

Author: Aristotelous, T., 2017

Supervisor: Hopkins, A. (Supervisor) & Hopkins Navratilova, I. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

African Trypanosome Genes Specifically Required for Fitness in vivo

Author: Shrimpton, J. W., 2017

Supervisor: Horn, D. (Supervisor)

Student thesis: Master's ThesisMaster of Science

File

Arsenic, antimony and visceral leishmaniasis

Author: Perry, M. R., 2014

Supervisor: Fairlamb, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File