Keyphrases
Trypanosoma Brucei
100%
GPI-anchored Protein (GPI-AP)
43%
Trypanosome
40%
Plasmodium Falciparum
39%
T. Brucei
34%
Trypanosoma Cruzi (T. cruzi)
34%
African Trypanosomes
32%
Drug Discovery
29%
Spike Glycoprotein
24%
Leishmania
24%
Drug Target
23%
Bloodstream Forms
20%
Trypanosomatids
19%
Leishmania Major
18%
Active Sites
18%
Proteolysis Targeting chimera (PROTAC)
18%
Human African Trypanosomiasis
16%
Leishmania Donovani
16%
Small Molecules
15%
Malaria
15%
Trypanothione Reductase
14%
Plasmodium
14%
Mycobacterium Tuberculosis (M. tb)
13%
Eukaryotes
13%
Chagas Disease
12%
Protein Kinase
12%
Recombinant
12%
Drug Resistance
12%
Binding Site
11%
Protozoan Parasites
11%
Phosphorylation
11%
Antitrypanosomal Activity
11%
High-throughput Screening
10%
Trypanothione
10%
Visceral Leishmaniasis
10%
Mode of Action
10%
Membrane Anchor
10%
Degrader
10%
Kinetoplastid
9%
Putative Drug Targets
9%
Phosphate
9%
Virulence
9%
Glycoconjugates
9%
Bromodomain
9%
Antigenic Variation
9%
Dundee
9%
Escherichia Coli
8%
RNA Interference
8%
Structure-activity Relationship
8%
New Drugs
8%
E3 Ubiquitin Ligase
8%
Potent Inhibitor
8%
Causative Agents
8%
Methyl
8%
High-throughput
8%
Biosynthetic Pathway
8%
Inositol
8%
E3 Ligase
8%
Protein-protein Interaction
8%
Metabolism
8%
Gene Expression
8%
GlcNAc
8%
Procyclic Form
7%
Knockdown
7%
Fragment Screening
7%
Null mutant
7%
Atopic Dermatitis
7%
Amino
7%
Ubiquitin
7%
Lipophosphoglycan
7%
African Sleeping Sickness
7%
N-acetyltransferase 2 (NAT2)
7%
Leishmaniasis
7%
Mechanism of Action
7%
Structure-based Design
7%
Glycoprotein
7%
Ternary Complex
7%
Von Hippel-Lindau
7%
Glycans
7%
Methylenetetrahydrofolate Reductase (MTHFR)
7%
Molecular Targets
7%
Antimalarial Drugs
6%
Trypanocidal Activity
6%
Small Molecule Inhibitors
6%
Mouse Model
6%
Transferases
6%
Macrophages
6%
Medicinal Chemistry
6%
N-myristoyltransferase
6%
Eukaryotic Cells
6%
Drug Development
6%
Chemical Synthesis
6%
Myo-inositol
6%
Phenotypic Screening
6%
Gene Regulation
6%
Selective Inhibitor
6%
Binding Mode
6%
Chemical Probes
6%
Pteridine Reductase 1
6%
Promastigote
6%
Biochemistry, Genetics and Molecular Biology
Enzyme
61%
Trypanosoma Brucei
61%
Trypanosoma
46%
Anabolism
28%
Crystal Structure
26%
Glycosylphosphatidylinositol
24%
Glycoprotein
22%
Small Molecule
22%
Binding Site
18%
Phosphotransferase
18%
Kinase
18%
Plasmodium falciparum
16%
Active Site
16%
Proteolysis
15%
Trypanosomatidae
14%
Proteomics
14%
Plasmodium
13%
Eukaryote
13%
Ubiquitin Ligase
13%
Oxidoreductase
12%
Gene Expression
12%
Ubiquitin
12%
Leishmania
12%
RNA
12%
Proteome
12%
Conformation
11%
Ubiquitin-Conjugating Enzyme
11%
Transcription
11%
Bromodomain
11%
Protozoon
10%
Protein Kinases
10%
Genetics
10%
Infectious Agent
10%
Transferase
10%
Leishmania Major
10%
Trypanosoma Cruzi
10%
Polysaccharide
10%
N-Terminus
9%
Binding Protein
9%
Reductase
9%
Messenger RNA
9%
Precursor
9%
C-Terminus
9%
Trypanothione
9%
Metabolic Pathway
8%
Escherichia coli
8%
Uridine Diphosphate
8%
Drug Resistance
8%
Inositol
8%
Protein Catabolism
7%
Ternary Complex
7%
Membrane Anchor
7%
Protein-Protein Interaction
7%
Copurification
7%
RNAI
7%
Glycosylation
7%
N-Acetyltransferase
7%
Amino Acids
7%
Phosphatidylinositol
7%
Adenosine Triphosphate
7%
Mycobacterium Tuberculosis
6%
Posttranslational Modification
6%
Lipid
6%
Ligand Binding
6%
Galactose
6%
Solution and Solubility
6%
Glycosyl
6%
Wild Type
6%
Protease
6%
Mass Spectrometry
6%
Ubiquitination
6%
Dynamics
6%
Synthase
6%
Histone
6%
Serine
5%
Protein Complexes
5%
Glycoconjugate
5%
Antigenic Variation
5%
Epigenetics
5%
Ribozyme
5%
Genomics
5%
Kinetoplastida
5%
Homeostasis
5%
Chitinase
5%
Isoform
5%
Cell Cycle
5%
Glycosyltransferase
5%
Proteasome
5%
Gene Linkage
5%
T Cell
5%