Biological Chemistry and Drug Discovery

Finished

Characterisation of the Ess Protein Secretion System of Staphylococcus Aureus a Key Virulence Factor

Hunter, B. (Investigator) & Palmer, T. (Investigator)

1/04/15 → 31/05/18

Project: Research

High Throughput Biolayer Interferometry at Dundee for Anti-Microbial and Interaction Studies

Birch, P. (Investigator), Ciulli, A. (Investigator), Fairlamb, A. (Investigator), Gray, D. (Investigator), Hunter, B. (Investigator), Owen-Hughes, T. (Investigator), Palmer, T. (Investigator), Ryan, R. (Investigator), Sargent, F. (Investigator), Stanley-Wall, N. (Investigator) & van Aalten, D. (Investigator)

Biotechnology and Biological Sciences Research Council

22/01/15 → 21/01/16

Project: Research

Targeting the Surface PRoteome of Trypanosoma Cruzi (Newton001) (Joint with Federal University of Sao Paulo, Brazil)

Field, M. (Investigator) & Horn, D. (Investigator)

Medical Research Council

1/01/15 → 31/12/15

Project: Research

Modes of Action and Resistance Mechanisms towards Anti-Trypanocidal Benzoxaboroles (Joint with University of Glasgow)

Field, M. (Investigator) & Horn, D. (Investigator)

Medical Research Council

1/01/15 → 31/12/17

Project: Research

Chemical Biology: Leveraging Phenotypic Hits Against Kinetoplastids (Strategic Grant)

Fairlamb, A. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Horn, D. (Investigator) & Wyatt, P. (Investigator)

1/01/15 → 31/12/20

Project: Research

Keratinizing Skin Disorder: From Systems Biology to Targeted Therapeutics (New Investigator Award)

Leslie Pedrioli, D. (Investigator)

Medical Research Council

1/07/14 → 30/06/17

Project: Research

Hidden Fats: Allosteric and Direct Mechanisms of Lipid Signalling Through GPCRs (CASE Studentship)

Zachariae, U. (Investigator)

Biotechnology and Biological Sciences Research Council

1/04/14 → 31/03/19

Project: Research

Melarsoprol-Pentamidine Cross Resistance in African Trypanosomes.

Horn, D. (Investigator)

Medical Research Council

28/10/13 → 27/10/16

Project: Research

Interactome Analysis of the Structure of the Trypanosome Nuclear Lamina and Other Complexes

Field, M. (Investigator)

21/10/13 → 20/05/14

Project: Research

Maintenance of the Cells Surface of Trypanosomes

Field, M. (Investigator)

21/10/13 → 20/05/15

Project: Research

Defining and Leveraging the Mechanism of Action of Suramin for Treatment of Trypanosomiasis (joint with University of Cambridge)

Field, M. (Investigator) & Horn, D. (Investigator)

Medical Research Council

21/10/13 → 20/06/16

Project: Research

Genetic Analysis in Keratoderma

Smith, F. (Investigator)

1/10/13 → 1/10/15

Project: Research

Mechanisms of Drug Resistance and Immune Evasion in African Trypanosomes

Horn, D. (Investigator)

1/09/13 → 31/03/14

Project: Research

High-Throughput Decoding of Virulence Mechanisms in African Trypanosomes (Senior Investigator Award)

Horn, D. (Investigator)

1/09/13 → 29/02/20

Project: Research

Chromosal Recombination and Repair in African Trypanosomes (joint with University of Glasgow)

Horn, D. (Investigator)

1/09/13 → 30/04/14

Project: Research

Macrophage Responses to Anti-Leishmanial Drug Treatment

Wyllie, S. (Investigator)

British Society for Antimicrobial Chemotherapy

1/01/13 → 30/06/14

Project: Research

State of the Art Pulse EPR Instrumentation for Long Range Distance Measurements in Biomacromolecules (Multi-User Equipment Grant) (Joint with University of St Andrews)

Hunter, B. (Investigator), Keeble, D. (Investigator), Lilley, D. (Investigator), Norman, D. (Investigator) & Owen-Hughes, T. (Investigator)

24/09/12 → 23/09/17

Project: Research

Pachyonychia Congenita Patient Support Meeting

Smith, F. (Investigator)

1/06/12 → 30/11/12

Project: Research

State-of-the-Art Facilities for Structural Biology at the University of Dundee

Hunter, B. (Investigator), Lilley, D. (Investigator), Owen-Hughes, T. (Investigator), Wyatt, P. (Investigator) & van Aalten, D. (Investigator)

1/03/12 → 28/02/17

Project: Research

Developing an Assay to Implement Screening for Differentiation-Inducing and/or Cytotoxic Agents of Cancer Stem Cells for the Potential Development of Pancreatic Cancer Therapeutics

Gray, D. (Investigator) & McElroy, S. (Investigator)

1/02/12 → 31/07/13

Project: Research

Genetic Screening in Pachyonychia Congenita

Smith, F. (Investigator)

1/10/11 → 30/09/13

Project: Research

Analysis of Rare-Keratinizing Disorders by Whole Exome Sequencing

Smith, F. (Investigator)

1/10/11 → 30/09/12

Project: Research

Discovery and Development of Drug Candidates for Neglected Diseases (joint with industrial partner)

Brenk, R. (Investigator), Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Hopkins, A. (Investigator), Horn, D. (Investigator), Read, K. (Investigator), Wyatt, P. (Investigator) & van Aalten, D. (Investigator)

1/02/11 → 1/07/17

Project: Research

Aref#d: 21992. Form and Function in the ESX-1 Secretion System; Elucidation of Mechanism and Structural Determinants of Bacterial Virulence

Hunter, B. (Investigator) & Palmer, T. (Investigator)

1/04/10 → 18/08/13

Project: Research

Aref#d: 21558. SIRNA Therapy in Dominant Skin and Eye Disorders (Programme Grant)

McLean, I. (Investigator) & Smith, F. (Investigator)

Medical Research Council

18/02/10 → 17/02/15

Project: Research

Aref#d: 22450. Capital Award in Biomedical Science - The Centre for Molecular Medicine (CMM)

Colhoun, H. (Investigator), Leigh, I. (Investigator), Marshall, S. (Investigator), McLean, I. (Investigator), Morris, A. (Investigator), Panteleyev, A. (Investigator), Proby, C. (Investigator), Schweiger, S. (Investigator), Smith, F. (Investigator), South, A. (Investigator) & Sutherland, C. (Investigator)

1/09/09 → 31/08/14

Project: Research