Biological Chemistry and Drug Discovery

Finished

Development Of An Anti-Malarial Drug Discovery Pipeline In Ghana (Joint with University Of Ghana and KHUST - Kwame Nkrumah University Of Science And Technology)

Gilbert, I., Read, K. & Wyllie, S.

Bill and Melinda Gates Foundation

18/03/22 → 17/04/23

Project: Research

Purchase of Sample Handling Robot And Mass Spec For Structural Spectrometry Drug Screening

Ferguson, M. & Masson, G.

Biotechnology and Biological Sciences Research Council

1/06/21 → 31/05/22

Project: Research

DCAF E3 Ligase Exploration To Expand degRadation (DELETER)

Ciulli, A.

COMMISSION OF THE EUROPEAN COMMUNITIES

1/05/21 → 30/04/23

Project: Research

Optimisation of Multistage Inhibitors of P. Falciparum Lysyl-t-RNA Synthetase for the Treatment of Malaria (joint with Eisai Pharmaceuticals and Medicines for Malaria Venture)

Gilbert, I., Gray, D., Read, K. & Wyatt, P.

1/04/21 → 31/03/23

Project: Research

Structure-Based PROTAC Design In-Silico (SBPD In Silico)

Ciulli, A.

COMMISSION OF THE EUROPEAN COMMUNITIES

1/02/21 → 31/01/23

Project: Research

Early Stage Challenge Fund Application - HGSP Covid Response RNACapRx (High Growth Spin Out Programme)

Cowling, V. & Gray, D.

14/09/20 → 31/03/21

Project: Research

Rapid Research in Covid -19 Programme

Barrable, A., Belch, J., Boehnke, J., Booth, D., Brown, A., Cantrell, D., Chalmers, J., Coleman, S., Connell, D., Cuschieri, A., Dicker, A., Doney, A., Eftimie, R., Fang, M., Farre, A., Gamble, C., Howden, A., Krstajic, N., Lamond, A., Lee, M., Palmer, C., Parcell, B., Pearson, E., Shoemark, A. & Sixsmith, J.

1/06/20 → 30/09/21

Project: Research

Dundee - Confidence in Concept 2019

Brady, J., Brady, J., Ferguson, M., Gray, D. & Wyatt, P.

Medical Research Council

31/03/20 → 1/04/23

Project: Research

A Drug Target for Shigella (Open Lab Programme)

Gilbert, I., Gray, D. & Read, K.

17/10/19 → 16/02/23

Project: Research

PPM1H Activators for Treatment of Parkinson's Disease

Alessi, D. & Gray, D.

1/09/19 → 30/03/21

Project: Research

Genetic Validation of a Promising Drug Target for Cryptosporidiosis

Baragana, B., Gilbert, I., Pawlowic, M. & Wyllie, S.

Carnegie Trust for the Universities of Scotland

20/08/19 → 19/02/21

Project: Research

The Innovative Targets Portfolio: Basic Life Sciences Research to Novel Therapies, through a Portfolio of Small Molecule Translational Projects

Ferguson, M., Gray, D. & Wyatt, P.

Medical Research Council

1/07/19 → 30/06/22

Project: Research

Development of New Agents for the Treatment of Cryptosporidiosis (DPFS) (Joint with University of Vermont)

Gilbert, I., Gray, D., Pawlowic, M., Read, K. & Wyatt, P.

Medical Research Council

1/05/19 → 31/01/23

Project: Research

Converting Natural Product Leads into Structure and Ligand Based Drug Discovery Campaigns against Leishmaniasis and Chagas' Disease (Joint with Sao Paulo State University)

Gilbert, I., Read, K. & Wyllie, S.

Medical Research Council

1/04/19 → 31/03/22

Project: Research

Defining the Function of Cryptosporidium Oocyst Wall Proteins in Parasite Transmission

Gilbert, I. & Pawlowic, M.

27/03/19 → 26/03/20

Project: Research

Drug Discovery Collaboration - Tau Seeding

Gray, D.

1/03/19 → 30/11/21

Project: Research

Identification and Validation of the Targets of Compounds Demonstrating In Vitro Activity Against Trypanosoma Cruzi (Newton International Fellowship)

Wyllie, S.

1/03/19 → 1/09/21

Project: Research

Developing Small Molecule Cancer Therapeutics Targeting the RNA Splicing Machinery: Target Validation on STRAP/UNRIP

Gray, D., Lamond, A., Petty, R. & Wyatt, P.

Cancer Research UK

1/10/18 → 31/12/20

Project: Research

Novel PROTAC-based Chemical Biology Approaches to Induced Protein Knockdown Across the Proteome (PhD Studentship - with Boehringer Ingelheim)

Ciulli, A. & Sapkota, G.

1/09/18 → 2/09/22

Project: Research

Industrial Strategy MRC DTP Studentship for the University of Dundee

Hunter, B. & MacKintosh, C.

Medical Research Council

1/09/18 → 28/02/22

Project: Research

MRC Proximity to Discovery 2017

Brady, J., Brady, J., Ferguson, M. & Wyatt, P.

Medical Research Council

1/03/18 → 30/09/21

Project: Research

MRC Confidence in Concept 2018

Ferguson, M., Gray, D. & Wyatt, P.

Medical Research Council

1/03/18 → 29/02/20

Project: Research

Development of an Image-Based High Throughput Screening Platform in Full Thickness Skin (Tools and Resources Development Fund: Bioimaging)

Conneely, M. & Hickerson, R.

Biotechnology and Biological Sciences Research Council

1/10/17 → 30/09/19

Project: Research

University of Dundee NPIF Studentships 2017

Hunter, B.

Medical Research Council

1/09/17 → 28/02/21

Project: Research

Mode of Action Studies in Kinetoplastid Parasites (Industrial CASE Studentship)

Gilbert, I. & Horn, D.

Medical Research Council

1/09/17 → 30/09/21

Project: Research

Targeting the Neuroepithelial Transforming Gene 1 (NET1)-PH/RhoA Interface to Fight the Invasive Phenotype of the Gastric Adenocarcinoma

Gray, D. & Petit, A.

6/03/17 → 5/03/18

Project: Research

The Innovative Targets Portfolio: Basic Life Sciences Research to Novel Therapies, through a Portfolio of Small Molecule Translational Projects

Ferguson, M., Gray, D. & Wyatt, P.

Medical Research Council

1/03/17 → 28/02/19

Project: Research

Increasing the Translational Impact of Drug Discovery

Brady, J., Ferguson, M. & Wyatt, P.

Medical Research Council

1/03/17 → 31/08/18

Project: Research

SHORTEN-TB: Developing Leads to Shorten Duration of TB Chemotherapy (Joint with NIH NIAD, University of Cambridge, University of Cape Town Braunschweig Germany)

Gilbert, I., Gray, D., Read, K. & Wyatt, P.

National Institutes of Health

23/01/17 → 22/01/20

Project: Research

Global Mechanisms for Control of the Trypanosome Proteome: Defining the Composition, Origins and Roles of Cullin E3 Ligases

Field, M.

Medical Research Council

1/01/17 → 31/12/19

Project: Research

An Antibacterial Drug Discovery Accelerator

Ferguson, M. & Gilbert, I.

1/01/17 → 31/03/17

Project: Research

Anchor E3s

Ciulli, A. & Lucas, X.

COMMISSION OF THE EUROPEAN COMMUNITIES

1/08/16 → 31/07/18

Project: Research

Control of Gene Expression in Trypanosoes: Defining the Nuclear Lamina

Field, M.

Medical Research Council

1/07/16 → 29/02/20

Project: Research

Hit Discovery for Schistosomiasis (Pathfinder) (Joint with University of Aberystwyth)

Gilbert, I., Gray, D. & Read, K.

Wellcome Trust

1/07/16 → 30/06/19

Project: Research

Innovative Targets Portfolio: Basic Life Sciences Research to Novel Therapies, through a Portfolio of Small Molecule Translational Projects (Confidence in Concept)

Ferguson, M., Gray, D. & Wyatt, P.

Medical Research Council

1/03/16 → 28/02/18

Project: Research

Increasing the Translational Impact of Drug Discovery (Proximity to Discovery 2015)

Brady, J., Ferguson, M. & Wyatt, P.

Medical Research Council

1/03/16 → 31/08/17

Project: Research

Understanding the Molecular Details as the Basis of Epigenetic Readers Function (Fellowship)

Bortoluzzi, A. & Ciulli, A.

1/10/15 → 30/09/16

Project: Research

Novel Antisense Technology for Treating Epidermolysis Bullosa Simplex (Clinical Fellowship)

Hickerson, R., McLean, I. & van Steensel, M.

1/10/15 → 3/01/23

Project: Research

Bump-BET; Bump and Hole Approach to Ellucidate Function of Individual Bromodomains of BET Proteins (Marie Curie Fellowship)

Chan, K. H. & Ciulli, A.

COMMISSION OF THE EUROPEAN COMMUNITIES

1/10/15 → 30/09/17

Project: Research

Lipopolysaccharide Translocation Across the Gram-Negative Inner Membrane: Development and Exploitation of Reagents and Knowledge to Guide Early Stage Drug Discovery(EPSRC-DSTL Industrial CASE Studentship)

Hunter, B.

Engineering and Physical Sciences Research Council

1/10/15 → 1/10/19

Project: Research

Development of Objective Clinical Endpoint for Skin Blistering Disorders

Campbell, P., Hickerson, R., McLean, I. & van Steensel, M.

1/09/15 → 30/09/18

Project: Research

Development of Filaggrin Upregulating Compounds for Treatment of Ichthyosis Vulgaris, Dry Skin and Eczema

Hickerson, R. & McLean, I.

British Skin Foundation

3/04/15 → 2/04/18

Project: Research

Characterisation of the Ess Protein Secretion System of Staphylococcus Aureus a Key Virulence Factor

Hunter, B. & Palmer, T.

Medical Research Council

1/04/15 → 31/05/18

Project: Research

Increasing the Translational Impact of Drug Discovery (Proximity to Discovery: Industry Engagement Fund)

Ferguson, M. & Wyatt, P.

Medical Research Council

1/03/15 → 31/08/16

Project: Research

The Innovative Targets Portfolio: Basic Life Sciences Research to Novel Therapies, Through a Portfolio of Small Molecule Translational Projects (Confidence in Concept award)

Ferguson, M., Woodland, A. & Wyatt, P.

Medical Research Council

1/03/15 → 31/08/16

Project: Research

High Throughput Biolayer Interferometry at Dundee for Anti-Microbial and Interaction Studies

Birch, P., Ciulli, A., Fairlamb, A., Gray, D., Hunter, B., Owen-Hughes, T., Palmer, T., Ryan, R., Sargent, F., Stanley-Wall, N. & van Aalten, D.

Biotechnology and Biological Sciences Research Council

22/01/15 → 21/01/16

Project: Research

Targeting the Surface PRoteome of Trypanosoma Cruzi (Newton001) (Joint with Federal University of Sao Paulo, Brazil)

Field, M. & Horn, D.

Medical Research Council

1/01/15 → 31/12/15

Project: Research

Modes of Action and Resistance Mechanisms towards Anti-Trypanocidal Benzoxaboroles (Joint with University of Glasgow)

Field, M. & Horn, D.

Medical Research Council

1/01/15 → 31/12/17

Project: Research

Chemical Biology: Leveraging Phenotypic Hits Against Kinetoplastids (Strategic Grant)

Fairlamb, A., Field, M., Gilbert, I., Gray, D., Horn, D. & Wyatt, P.

Wellcome Trust

1/01/15 → 31/12/20

Project: Research

Keratinizing Skin Disorder: From Systems Biology to Targeted Therapeutics (New Investigator Award)

Leslie Pedrioli, D.

Medical Research Council

1/07/14 → 30/06/17

Project: Research

Biological Chemistry and Drug Discovery

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