Biological Chemistry and Drug Discovery &ndash; Projects

Active

PPM1H Activators for Treatment of Parkinson's Disease

Alessi, D. & Gray, D.

9/09/19 → 8/09/20

Project: Research

Genetic Validation of a Promising Drug Target for Cryptosporidiosis

Baragana, B., Gilbert, I., Pawlowic, M. & Wyllie, S.

Carnegie Trust for the Universities of Scotland

26/08/19 → 25/08/20

Project: Research

The Innovative Targets Portfolio: Basic Life Sciences Research to Novel Therapies, through a Portfolio of Small Molecule Translational Projects

Ferguson, M., Gray, D. & Wyatt, P.

Medical Research Council

1/07/19 → 30/06/21

Project: Research

Development of New Agents for the Treatment of Cryptosporidiosis (DPFS) (Joint with University of Vermont)

Gilbert, I., Gray, D., Pawlowic, M., Read, K. & Wyatt, P.

Medical Research Council

1/05/19 → 31/12/21

Project: Research

Converting Natural Product Leads into Structure and Ligand Based Drug Discovery Campaigns against Leishmaniasis and Chagas' Disease (Joint with Sao Paulo State University)

Gilbert, I., Read, K. & Wyllie, S.

Medical Research Council

1/04/19 → 31/03/22

Project: Research

Defining the Function of Cryptosporidium Oocyst Wall Proteins in Parasite Transmission

Gilbert, I. & Pawlowic, M.

Royal Society

27/03/19 → 26/03/20

Project: Research

Drug Discovery Collaboration - Tau Seeding

Gray, D.

1/03/19 → 31/08/21

Project: Research

Identification and Validation of the Targets of Compounds Demonstrating In Vitro Activity Against Trypanosoma Cruzi (Newton International Fellowship)

Wyllie, S.

Royal Society

1/03/19 → 28/02/21

Project: Research

Defining Oocyst Wall Biogenesis and Function in Cryptosporidium Transmission (Reference #UNS68421) (Sir Henry Dale Fellowship)

Gilbert, I. & Pawlowic, M.

Wellcome Trust

1/02/19 → 31/01/24

Project: Research

Structure-Guided Drug Discovery for Malaria and Tuberculosis (joint with Structural Genomics Consortium)

Gilbert, I., Gray, D., Read, K. & Wyatt, P.

Bill and Melinda Gates Foundation

1/01/19 → 1/07/21

Project: Research

Male Contraceptive Drug Development Using a Novel Human Sperm Phenotypic Screening Platform (Grand Challenges Phase II)

Andrews, P., Barratt, C., Gilbert, I., Martins Da Silva, S. & Read, K.

Bill and Melinda Gates Foundation

1/11/18 → 31/10/20

Project: Research

Developing Small Molecule Cancer Therapeutics Targeting the RNA Splicing Machinery: Target Validation on STRAP/UNRIP

Gray, D., Lamond, A., Petty, R. & Wyatt, P.

Cancer Research UK

1/10/18 → 30/09/20

Project: Research

Industrial Collaborative Awards in Science and Engineering (iCASE) Studentships for the University of Dundee

Hunter, B. & MacKintosh, C.

Medical Research Council

3/09/18 → 31/03/23

Project: Research

Novel PROTAC-based Chemical Biology Approaches to Induced Protein Knockdown Across the Proteome (PhD Studentship - with Boehringer Ingelheim)

Ciulli, A. & Sapkota, G.

3/09/18 → 2/09/22

Project: Research

Industrial Strategy MRC DTP Studentship for the University of Dundee

Hunter, B. & MacKintosh, C.

Medical Research Council

1/09/18 → 28/02/22

Project: Research

MRC Proximity to Discovery 2017

Brady, J., Brady, J., Ferguson, M. & Wyatt, P.

Medical Research Council

1/03/18 → 30/09/20

Project: Research

MRC Confidence in Concept 2018

Ferguson, M., Gray, D. & Wyatt, P.

Medical Research Council

1/03/18 → 29/02/20

Project: Research

KRS Inhibitors: A Dundee Mini Portfolio

Gilbert, I., Gray, D., Read, K. & Wyatt, P.

1/01/18 → 1/01/20

Project: Research

A Systems Approach for Understanding Cell Surface Dynamics in Trypanosomes (Investigator Award)

Field, M.

Wellcome Trust

1/10/17 → 30/09/22

Project: Research

Development of an Image-Based High Throughput Screening Platform in Full Thickness Skin (Tools and Resources Development Fund: Bioimaging)

Conneely, M. & Hickerson, R.

Biotechnology and Biological Sciences Research Council

1/10/17 → 30/09/19

Project: Research

Mode of Action Studies in Kinetoplastid Parasites (Industrial CASE Studentship)

Gilbert, I. & Horn, D.

Medical Research Council

1/09/17 → 30/09/21

Project: Research

University of Dundee NPIF Studentships 2017

Hunter, B.

Medical Research Council

1/09/17 → 28/02/21

Project: Research

MICA: Delivering Gene Silencing Therapy to the Epidermis and Ocular Surface

Hickerson, R. & McLean, I.

Medical Research Council

1/06/17 → 31/08/22

Project: Research

Wellcome Centre for Anti-Infectives Research

Cook, S., Fairlamb, A., Ferguson, M., Field, M., Gilbert, I., Gray, D., Horn, D., Read, K. & Wyatt, P.

Wellcome Trust

1/04/17 → 31/03/22

Project: Research

Architecture of a Biofilm (Joint with University of Edinburgh)

Campbell, P., Davidson, F., Ferguson, M., Stanley-Wall, N. & Swedlow, J.

Biotechnology and Biological Sciences Research Council

1/02/17 → 31/01/22

Project: Research

SHORTEN-TB: Developing Leads to Shorten Duration of TB Chemotherapy (Joint with NIH NIAD, University of Cambridge, University of Cape Town Braunschweig Germany)

Gilbert, I., Gray, D., Read, K. & Wyatt, P.

National Institutes of Health

23/01/17 → 22/01/20

Project: Research

Global Mechanisms for Control of the Trypanosome Proteome: Defining the Composition, Origins and Roles of Cullin E3 Ligases

Field, M.

Medical Research Council

1/01/17 → 31/12/19

Project: Research

Training the Next Generation of Scientists in Quantitative and Interdisciplinary Approaches to Biomedical Science (Doctoral Training Partnership)

Hunter, B. & MacKintosh, C.

Medical Research Council

5/09/16 → 31/03/24

Project: Research

Control of Gene Expression in Trypanosoes: Defining the Nuclear Lamina

Field, M.

Medical Research Council

1/07/16 → 29/02/20

Project: Research

Lipopolysaccharide Translocation Across the Gram-Negative Inner Membrane: Development and Exploitation of Reagents and Knowledge to Guide Early Stage Drug Discovery(EPSRC-DSTL Industrial CASE Studentship)

Hunter, B.

Engineering and Physical Sciences Research Council

1/10/15 → 1/10/19

Project: Research

Novel Antisense Technology for Treating Epidermolysis Bullosa Simplex (Clinical Fellowship)

Hickerson, R., McLean, I. & van Steensel, M.

1/10/15 → 31/07/20

Project: Research

Chemical Biology: Leveraging Phenotypic Hits Against Kinetoplastids (Strategic Grant)

Fairlamb, A., Field, M., Gilbert, I., Gray, D., Horn, D. & Wyatt, P.

Wellcome Trust

1/01/15 → 30/06/20

Project: Research

Protein Glycosylation in Trypanosomes: Defining and Exploiting a Biological System (Senior Investigator Award)

Ferguson, M.

Wellcome Trust

1/10/13 → 30/09/20

Project: Research

High-Throughput Decoding of Virulence Mechanisms in African Trypanosomes (Senior Investigator Award)

Horn, D.

Wellcome Trust

1/09/13 → 29/02/20

Project: Research