Research output per year
Research output per year
Research output
- 50 - 100 out of 2,067 results
Search results
-
2023
Chemical pulldown combined with mass spectrometry to identify the molecular targets of antimalarials in cell-free lysates
Smith, R. J., Milne, R., Lopez, V. C., Wiedemar, N., Dey, G., Syed, A. J., Patterson, S. (Lead / Corresponding author) & Wyllie, S. (Lead / Corresponding author), 17 Mar 2023, In: STAR Protocols. 4, 1, 30 p., 102002.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)132 Downloads (Pure) -
Classification of likely functional state for ligand binding sites identified from fragment screening
Utgés, J. S., MacGowan, S. A., Ives, C. M. & Barton, G. J., 24 Jul 2023, Research Square.Research output: Working paper/Preprint › Preprint
Open Access -
Comparative Genomics for Evolutionary Cell Biology Using AMOEBAE: Understanding the Golgi and Beyond
Barlow, L. D. (Lead / Corresponding author), Maciejowski, W., More, K., Terry, K., Vargová, R., Záhonová, K. & Dacks, J. B. (Lead / Corresponding author), 2023, Golgi: Methods and Protocols. Wang, Y., Lupashin, V. V. & Graham, T. R. (eds.). New York: Humana Press, p. 431-452 22 p. (Methods in Molecular Biology; vol. 2557).Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
7 Citations (Scopus) -
Comparison of real-world treatment outcomes of systemic immunomodulating therapy in atopic dermatitis patients with dark and light skin types
Bosma, A. L. (Lead / Corresponding author), Ouwerkerk, W., Heidema, M. J., Prieto-Merino, D., Ardern-Jones, M. R., Beattie, P., Brown, S. J., Ingram, J. R., Irvine, A. D., Ogg, G., Patel, P., Reynolds, N. J., Hearn, R. M. R., Wan, M., Warren, R. B., Woolf, R. T., Hyseni, A. M., Gerbens, L. A. A., Spuls, P. I. & Flohr, C. & 3 others, , 1 Mar 2023, In: JAAD International. 10, p. 14-24 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)134 Downloads (Pure) -
Competition among variants is predictable and contributes to the antigenic variation dynamics of African trypanosomes
Escrivani, D. O., Scheidt, V., Tinti, M., Correia Faria, J. & Horn, D. (Lead / Corresponding author), 17 Jul 2023, In: PLoS Pathogens. 19, 7, 21 p., e1011530.Research output: Contribution to journal › Article › peer-review
Open AccessFile64 Downloads (Pure) -
Crystallization of VHL-based PROTAC-induced ternary complexes
Wijaya, A. J., Farnaby, W. & Ciulli, A. (Lead / Corresponding author), 2023, Targeted Protein Degradation. Burslem, G. L. (ed.). Academic Press Inc., Vol. 681. p. 241-263 23 p. (Methods in Enzymology).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Citations (Scopus) -
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target
Istvan, E. S., Guerra, F., Abraham, M., Huang, K. S., Rocamora, F., Zhao, H., Xu, L., Pasaje, C., Kumpornsin, K., Luth, M. R., Cui, H., Yang, T., Diaz, S. P., Gomez-Lorenzo, M. G., Qahash, T., Mittal, N., Ottilie, S., Niles, J., Lee, M. C. S. & Llinas, M. & 7 others, , 8 Mar 2023, In: Science Translational Medicine. 15, 686, eadc9249.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Defining early steps in Bacillus subtilis biofilm biosynthesis
Arbour, C. A., Nagar, R., Bernstein, H. M., Ghosh, S., Al-Sammarraie, Y., Dorfmueller, H. C., Ferguson, M. A. J., Stanley-Wall, N. R. (Lead / Corresponding author) & Imperiali, B. (Lead / Corresponding author), 31 Oct 2023, In: MBio. 14, 5, 21 p., e00948-23.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)76 Downloads (Pure) -
Design and synthesis of covalent inhibitors of FabA
Martin, J. S., Mackenzie, C. J., Lin, D., Homeyer, N., Gray, D. W., Zuccotto, F. & Gilbert, I. H. (Lead / Corresponding author), 11 Apr 2023, In: ACS Omega. 8, 14, p. 12787–12804 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile89 Downloads (Pure) -
Development of a 2,4-diaminothiazole series for the treatment of human African trypanosomiasis highlights the importance of static-cidal screening of analogues
Cleghorn, L. A. T., Wall, R. J., Albrecht, S., MacGowan, S. A., Norval, S., De Rycker, M., Woodland, A., Spinks, D., Thompson, S., Patterson, S., Corpas Lopez, V., Dey, G., Collie, I. T., Hallyburton, I., Kime, R., Simeons, F. R. C., Stojanovski, L., Frearson, J. A., Wyatt, P. G. & Read, K. D. & 2 others, , 13 Jul 2023, In: Journal of Medicinal Chemistry. 66, 13, p. 8896–8916 21 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)79 Downloads (Pure) -
Deviating from the norm: Nuclear organisation in trypanosomes
Field, M. C. (Lead / Corresponding author), Dec 2023, In: Current Opinion in Cell Biology. 85, 12, 7 p., 102234.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)50 Downloads (Pure) -
Discovery of new E3 ligases for alpha-synuclein clearance
Kocaturk, N. (Lead / Corresponding author), Li, Z., Ganley, I. & Sapkota, G. P., 28 Jun 2023, In: Journal of Parkinson's Disease. 13, S1, p. 74 1 p., P03.05.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc1
Braillard, S., Keenan, M., Breese, K. J., Heppell, J., Abbott, M., Islam, R., Shackleford, D. M., Katneni, K., Crighton, E., Chen, G., Patil, R., Lee, G., White, K. L., Carvalho, S., Wall, R. J., Chemi, G., Zuccotto, F., Gonzalez, S., Marco, M. & Deakyne, J. & 18 others, , 13 Dec 2023, In: Science Translational Medicine. 15, 726, 15 p., eadh9902.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)95 Downloads (Pure) -
Endosomal vesicle fusion machinery is involved with the contractile vacuole in Dictyostelium discoideum
Manna, P. T. (Lead / Corresponding author), Barlow, L. D., Ramirez-Macias, I., Herman, E. K. & Dacks, J. B. (Lead / Corresponding author), 18 Jan 2023, In: Journal of Cell Science. 136, 2, 8 p., jcs260477.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Ethanolaminephosphate cytidyltransferase is essential for survival, lipid homeostasis and stress tolerance in Leishmania major
Basu, S., Pawlowic, M., Hsu, F.-F., Thomas, G. & Zhang, K. (Lead / Corresponding author), 11 Jan 2023, Cold Spring Harbor Laboratory: BioRxiv, 66 p.Research output: Working paper/Preprint › Preprint
Open AccessFile65 Downloads (Pure) -
Ethanolaminephosphate cytidylyltransferase is essential for survival, lipid homeostasis and stress tolerance in Leishmania major
Basu, S., Pawlowic, M. C., Hsu, F.-F., Thomas, G. & Zhang, K. (Lead / Corresponding author), 28 Jul 2023, In: PLoS Pathogens. 19, 7, 28 p., e1011112.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)61 Downloads (Pure) -
Evolutionary, structural and functional insights in nuclear organisation and nucleocytoplasmic transport in trypanosomes
Padilla-Mejia, N. E. (Lead / Corresponding author) & Field, M. C., 24 Oct 2023, In: FEBS Letters. 597, 20, p. 2501-2518 18 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus)51 Downloads (Pure) -
Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel-Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1α Stabilizers
Vu, L. P., Diehl, C. J., Casement, R., Bond, A. G., Steinebach, C., Strašek, N., Bricelj, A., Perdih, A., Schnakenburg, G., Sosič, I., Ciulli, A. (Lead / Corresponding author) & Gütschow, M. (Lead / Corresponding author), 28 Sept 2023, In: Journal of Medicinal Chemistry. 66, 18, p. 12776-12811 36 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)87 Downloads (Pure) -
Extracellular vesicles secreted by Echinococcus multilocularis: Important players inangiogenesis promotion
Liu, C., Cao, J., Zhang, H., Field, M. C. & Yin, J. (Lead / Corresponding author), 1 Sept 2023, In: Microbes and Infection. 25, 7, 105147.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)257 Downloads (Pure) -
Functional differentiation of Sec13 paralogues in the euglenozoan protists
Drahomíra, F. (Lead / Corresponding author), Záhonová, K., Benz, C., Dacks, J. B., Field, M. & Lukeš, J. (Lead / Corresponding author), 14 Jun 2023, In: Open Biology. 13, 6, 15 p., 220364.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)87 Downloads (Pure) -
Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders
Hanzl, A., Casement, R., Imrichova, H., Hughes, S. J., Barone, E., Testa, A., Bauer, S., Wright, J., Brand, M., Ciulli, A. (Lead / Corresponding author) & Winter, G. E. (Lead / Corresponding author), Mar 2023, In: Nature Chemical Biology. 19, p. 323-333 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile44 Citations (Scopus)308 Downloads (Pure) -
Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum
Kümpornsin, K., Kochakarn, T., Yeo, T., Okombo, J., Luth, M. R., Hoshizaki, J., Rawat, M., Pearson, R. D., Schindler, K. A., Mok, S., Park, H., Uhlemann, A.-C., Jana, G. P., Maity, B. C., Laleu, B., Chenu, E., Duffy, J., Moliner Cubel, S., Franco, V. & Gomez-Lorenzo, M. G. & 5 others, , 27 May 2023, In: Nature Communications. 14, 14 p., 3059.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)81 Downloads (Pure) -
HiBiT Cellular Thermal Shift Assay (HiBiT CETSA)
Ramachandran, S., Szewczyk, M., Barghout, S. H., Ciulli, A., Barsyte-Lovejoy, D. & Vu, V. (Lead / Corresponding author), 2023, Chemogenomics: Methods and Protocols. Merk, D. & Chaikuad, A. (eds.). 1 ed. New York: Humana Press, p. 149-165 17 p. (Methods in Molecular Biology; vol. 2706).Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
Open AccessFile4 Citations (Scopus)68 Downloads (Pure) -
Identification of inhibitors for the transmembrane Trypanosoma cruzi eIF2α kinase relevant for parasite proliferation
de Paula Marcelino, T., Fala, A. M., da Silva, M. M., Souza-Melo, N., Malvezzi, A. M., Hollunder Klippel, A., Zoltner, M., Padilla-Mejia, N., Kosto, S., Field, M. C., de Assis Burle Caldas, G., Ribeiro Teixeira, S. M., Couñago, R. M., Brauer Massirer, K. (Lead / Corresponding author) & Schenkman, S. (Lead / Corresponding author), Jul 2023, In: Journal of Biological Chemistry. 299, 7, 18 p., 104857.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)93 Downloads (Pure) -
Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3
Röth, S., Kocaturk, N. M., Sathyamurthi, P. S., Carton, B., Watt, M., Macartney, T. J., Chan, K.-H., Isidro-Llobet, A., Konopacka, A., Queisser, M. A. & Sapkota, G. P. (Lead / Corresponding author), 19 Oct 2023, In: Cell Chemical Biology. 30, 10, p. 1261-1276.e7 23 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)98 Downloads (Pure) -
Identification of the glycosylphosphatidylinositol-specific phospholipase A2 (GPI-PLA2) that mediates GPI fatty acid remodeling in Trypanosoma brucei
Ji, Z., Nagar, R., Duncan, S. M., Sampaio Guther, M. L. & Ferguson, M. A. J. (Lead / Corresponding author), Aug 2023, In: Journal of Biological Chemistry. 299, 8, 13 p., 105016.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)72 Downloads (Pure) -
Impact of inherent biases built into proteomic techniques: Proximity labeling and affinity capture compared
Moreira, C. M. D. N., Kelemen, C. D., Obado, S. O., Zahedifard, F., Zhang, N., Holetz, F. B., Gauglitz, L., Dallagiovanna, B., Field, M. C., Kramer, S. (Lead / Corresponding author) & Zoltner, M. (Lead / Corresponding author), Jan 2023, In: Journal of Biological Chemistry. 299, 1, 15 p., 102726.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)164 Downloads (Pure) -
Integrative Genetic Manipulation of Plasmodium cynomolgi Reveals Multidrug Resistance-1 Y976F Associated With Increased In Vitro Susceptibility to Mefloquine
Ward, K. E., Christensen, P., Racklyeft, A., Dhingra, S. K., Chua, A. C. Y., Remmert, C., Suwanarusk, R., Matheson, J., Blackman, M. J., Kaneko, O., Kyle, D. E., Lee, M. C. S., Moon, R. W., Snounou, G., Rénia, L., Fidock, D. A., Russell, B. (Lead / Corresponding author) & Bifani, P., 15 May 2023, In: The Journal of infectious diseases. 227, 10, p. 1121-1126 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)49 Downloads (Pure) -
Integrative GWAS and co-localisation analysis suggests novel genes associated with age-related multimorbidity
West, C. E. (Lead / Corresponding author), Karim, M., Falaguera, M. J., Speidel, L., Green, C. J., Logie, L., Schwartzentruber, J., Ochoa, D., Lord, J. M., Ferguson, M. A. J., Bountra, C., Wilkinson, G. F., Vaughan, B., Leach, A. R., Dunham, I. & Marsden, B. D., 25 Sept 2023, In: Scientific Data. 10, 13 p., 655.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)51 Downloads (Pure) -
In Vitro Activity of Two Cefepime-Based Novel Combinations, Cefepime/Taniborbactam and Cefepime/Zidebactam, against Carbapenemase-Expressing Enterobacterales Collected in India
Bakthavatchalam, Y. D., Elangovan, D., Jaganathan, S. V., Subburaju, N., Shankar, A., Manokaran, Y., J., S., Devi, R., Baveja, S., Devi, S., S., J., Bhattacharya, S., M., R. S., Yesudhason, B., Shetty, V., Mutreja, A., Manesh, A., Varghese, G. M., Marwick, C. A. & Parcell, B. J. & 2 others, , 13 Apr 2023, In: Microbiology Spectrum. 11, 2, 10 p., e04925-22.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)146 Downloads (Pure) -
Lessons from the deep: mechanisms behind diversification of eukaryotic protein complexes
Prokopchuk, G., Butenko, A., Dacks, J. B., Speijer, D., Field, M. C. (Lead / Corresponding author) & Lukeš, J. (Lead / Corresponding author), Dec 2023, In: Biological reviews of the Cambridge Philosophical Society. 98, 6, p. 1910-1927 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)80 Downloads (Pure) -
Mechanical tension influences the immunocompetency of ex vivo skin tissue
Hickerson, R., Grussu, D., Tsutsumi, K., Campbell, P. & Conneely, M., 31 May 2023, In: Journal of Investigative Dermatology. 143, 5, p. S180 1 p., 1053.Research output: Contribution to journal › Meeting abstract › peer-review
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Mode of action studies confirm on-target engagement of lysyl-tRNA synthetase inhibitor and lead to new selection marker for Cryptosporidium
Hanna, J. C. .., Corpas Lopez, V., Seizova, S., Colon, B. L., Bacchetti, R., Hall, G. M. J., Sands, E. M., Robinson, L., Baragaña, B., Wyllie, S. (Lead / Corresponding author) & Pawlowic, M. (Lead / Corresponding author), 4 Aug 2023, In: Frontiers in Cellular and Infection Microbiology. 13, 14 p., 1236814.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)108 Downloads (Pure) -
Novel kinetoplastid-specific cAMP binding proteins identified by RNAi screening for cAMP resistance in Trypanosoma brucei
Bachmaier, S., Gould, M. K., Polatoglou, E., Omelianczyk, R., Brennand, A. E., Aloraini, M. A., Munday, J. C., Horn, D., Boshart, M. (Lead / Corresponding author) & de Koning, H. P. (Lead / Corresponding author), 5 Jul 2023, In: Frontiers in Cellular and Infection Microbiology. 13, 15 p., 1204707.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)47 Downloads (Pure) -
Phylogeny-wide analysis of G-protein coupled receptors in social amoebas and implications for the evolution of multicellularity: [version 2; peer review: 2 approved]
Hall, G., Kelly, S., Schaap, P. & Schilde, C. (Lead / Corresponding author), 15 Feb 2023, In: Open Research Europe. 2, 28 p., 134.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)110 Downloads (Pure) -
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation
Bopp, S., Pasaje, C. F. A., Summers, R. L., Magistrado-Coxen, P., Schindler, K. A., Corpas-Lopez, V., Yeo, T., Mok, S., Dey, S., Smick, S., Nasamu, A. S., Demas, A. R., Milne, R., Wiedemar, N., Corey, V., Gomez-Lorenzo, M. D. G., Franco, V., Early, A. M., Lukens, A. K. & Milner, D. & 10 others, , 16 Mar 2023, In: Nature Communications. 14, 15 p., 1455.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)62 Downloads (Pure) -
Propensity of selecting mutant parasites for the antimalarial drug cabamiquine
Stadler, E., Maiga, M., Friedrich, L., Thathy, V., Demarta-Gatsi, C., Dara, A., Sogore, F., Striepen, J., Oeuvray, C., Djimdé, A. A., Lee, M. C. S., Dembélé, L. (Lead / Corresponding author), Fidock, D. A. (Lead / Corresponding author), Khoury, D. S. (Lead / Corresponding author) & Spangenberg, T. (Lead / Corresponding author), 25 Aug 2023, In: Nature Communications. 14, 10 p., 5205.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)37 Downloads (Pure) -
Proximity-Based Modalities for Biology and Medicine
Liu, X. & Ciulli, A. (Lead / Corresponding author), 26 Jul 2023, In: ACS Central Science. 9, 7, p. 1269-1284 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile46 Citations (Scopus)132 Downloads (Pure) -
Public Engagement with Research and Scholarship Evaluation Framework 2023-2028
Cameron, A., Floyd, A., Hardee, E., Mackintosh, A. & Stanley-Wall, N., Sept 2023, Dundee: University of Dundee. 13 p.Research output: Book/Report › Other report
Open AccessFile215 Downloads (Pure) -
Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage (Nature Communications, (2018), 9, 1, (1107), 10.1038/s41467-018-03441-3)
Ladds, M. J. G. W., van Leeuwen, I. M. M., Drummond, C. J., Chu, S., Healy, A. R., Popova, G., Pastor Fernández, A., Mollick, T., Darekar, S., Sedimbi, S. K., Nekulova, M., Sachweh, M. C. C., Campbell, J., Higgins, M., Tuck, C., Popa, M., Safont, M. M., Gelebart, P., Fandalyuk, Z. & Thompson, A. M. & 26 others, , 18 Aug 2023, In: Nature Communications. 14, 1, 5019.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile1 Citation (Scopus)38 Downloads (Pure) -
RES-Seq – a barcoded library of drug-resistant Leishmania donovani allowing rapid assessment of cross-resistance and relative fitness
Tulloch, L. B., Carvalho, S., Lima, M., Wall, R. J., Tinti, M., Pinto, E. G., MacLean, L. & Wyllie, S. (Lead / Corresponding author), 19 Dec 2023, In: MBio. 14, 6, 15 p., e01803-23.Research output: Contribution to journal › Article › peer-review
Open AccessFile41 Downloads (Pure) -
Rhs NADase effectors and their immunity proteins are exchangeable mediators of interbacterial competition in Serratia
Hagan, M., Pankovs, G., Gallegos Monterrosa, R., Williams, D. J., Earl, C., Buchanan, G., Hunter, W. N. (Lead / Corresponding author) & Coulthurst, S. J. (Lead / Corresponding author), 28 Sept 2023, In: Nature Communications. 14, 16 p., 6061.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)77 Downloads (Pure) -
Roles of glycans in protozoal host-parasite interactions
Bandini, G. & Ferguson, M. A. J., 2023, Encyclopedia of Cell Biology. Bradshaw, R. A., Hart, G. W. & Stahl, P. D. (eds.). 2nd ed. London: Elsevier, Vol. 4. p. 363-372 10 p.Research output: Chapter in Book/Report/Conference proceeding › Entry for encyclopedia/dictionary
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Safe and effective treatments are needed for cryptosporidiosis, a truly neglected tropical disease
Gilbert, I. H., Vinayak, S., Striepen, B., Manjunatha, U. H., Khalil, I. A., Van Voorhis, W. C. (Lead / Corresponding author) & Cryptosporidiosis Therapeutics Advocacy Group CTAG, Aug 2023, In: BMJ Global Health. 8, 8, 6 p., e012540.Research output: Contribution to journal › Editorial › peer-review
Open AccessFile11 Citations (Scopus)66 Downloads (Pure) -
SBDD and Its Challenges
Chakraborti, S. (Lead / Corresponding author) & Sachchidanand, S., 2023, Current Trends in Computational Modeling for Drug Discovery. Kar, S. & Leszczynski, J. (eds.). 1 ed. Cham: Springer , p. 1-24 24 p. (Challenges and Advances in Computational Chemistry and Physics; vol. 35).Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Citation (Scopus) -
Short-course combination treatment for experimental chronic Chagas disease
González, S., Wall, R. J., Thomas, J., Braillard, S., Brunori, G., Camino Díaz, I., Cantizani, J., Carvalho, S., Castañeda Casado, P., Chatelain, E., Cotillo, I., Fiandor, J. M., Francisco, A. F., Grimsditch, D., Keenan, M., Kelly, J. M., Kessler, A., Luise, C., Lyon, J. J. & MacLean, L. & 10 others, , 13 Dec 2023, In: Science Translational Medicine. 15, 726, 17 p., adg8105.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)87 Downloads (Pure) -
SophosQM: Accurate Binding Affinity Prediction in Compound Optimization
Guareschi, R., Lukac, I., Gilbert, I. H. (Lead / Corresponding author) & Zuccotto, F. (Lead / Corresponding author), 2 May 2023, In: ACS Omega. 8, 17, p. 15083-15098 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)158 Downloads (Pure) -
Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2
Ramachandran, S., Makukhin, N., Haubrich, K., Nagala, M., Forrester, B., Lynch, D. M., Casement, R., Testa, A., Bruno, E., Gitto, R. & Ciulli, A. (Lead / Corresponding author), 10 Oct 2023, In: Nature Communications. 14, 17 p., 6345.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)73 Downloads (Pure) -
Structure Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors
Thomas, M. G., McGonagle, K., Rowland, P., Robinson, D. A., Dodd, P. G., Camino-Díaz, I., Campbell, L., Cantizani, J., Castañeda, P., Conn, D., Craggs, P. D., Edwards, D., Ferguson, L., Fosberry, A., Frame, L., Goswami, P., Hu, X., Korczynska, J., MacLean, L. & Martin, J. & 21 others, , 10 Aug 2023, In: Journal of Medicinal Chemistry. 66, 15, p. 10413-10431 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)114 Downloads (Pure) -
Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline
Kreutzfeld, O. (Lead / Corresponding author), Tumwebaze, P. K., Okitwi, M., Orena, S., Byaruhanga, O., Katairo, T., Conrad, M. D., Rasmussen, S. A., Legac, J., Aydemir, O., Giesbrecht, D., Forte, B., Campbell, P., Smith, A., Kano, H., Nsobya, S. L., Blasco, B., Duffey, M., Bailey, J. A. & Cooper, R. A. & 1 others, , 15 Jun 2023, In: Microbiology Spectrum. 11, 3, 14 p., e05236-22.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)73 Downloads (Pure)