Biological Chemistry and Drug Discovery

  • United Kingdom

Research Output 1972 2020

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Chapter (peer-reviewed)
2019

DiCre-Based Inducible Disruption of Leishmania Genes

Duncan, S. M., Myburgh, E., Alves-Ferreira, E. V. & Mottram, J. C., 2019, Leishmania: Methods and Protocols. Clos, J. (ed.). New York: Humana Press, Vol. 1971. p. 211-224 14 p. (Methods in Molecular Biology; vol. 1971).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Leishmania
Essential Genes
Gene Deletion
Genes
Enzyme Activation
2017
16 Citations (Scopus)

Euglena gracilis Genome and Transcriptome: Organelles, Nuclear Genome Assembly Strategies and Initial Features

Ebenezer, T. E., Carrington, M., Lebert, M., Kelly, S. & Field, M. C., 21 Apr 2017, Euglena: Biochemistry, Cell and Molecular Biology. Schwartzbach, S. D. & Shigeoka, S. (eds.). Switzerland: Springer International Publishing, p. 125-140 16 p. (Advances in Experimental Medicine and Biology; vol. 979).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Euglena gracilis
Transcriptome
Organelles
Genome
Plastid Genomes
1 Citation (Scopus)

Profiling phosphopeptide-binding domain recognition specificity using peptide microarrays

Tinti, M., Panni, S. & Cesareni, G., 2017, Small molecule microarrays: methods and protocols. Uttamchandani, M. & Yao, S. Q. (eds.). New York: Springer , p. 177-193 17 p. (Methods in molecular biology; vol. 1518).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Phosphopeptides
Phosphorylation
Peptides
Proteins
Threonine
2016
8 Citations (Scopus)

High-Efficiency Isolation of Nuclear Envelope Protein Complexes from Trypanosomes

Obado, S. O., Field, M. C., Chait, B. T. & Rout, M. P., 2016, The Nuclear Envelope. Shackleton, S., Collas, P. & Schirmer, E. C. (eds.). New York: Humana Press, p. 67-80 14 p. (Methods in Molecular Biology; vol. 1411).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Trypanosomiasis
Nuclear Envelope
Nuclear Proteins
Protein Interaction Maps
Nuclear Pore
2 Citations (Scopus)

Imaging functional nucleic acid delivery to skin

Kaspar, R. L., Hickerson, R. P., González-González, E., Flores, M. A., Speaker, T. P., Rogers, F. A., Milstone, L. M. & Contag, C. H., 2016, RNA Imaging: methods and protocols. Medarova, Z. (ed.). New York: Springer , p. 1-24 24 p. (Methods in molecular biology; vol. 1372).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Nucleic Acids
Skin
Reporter Genes
Small Interfering RNA
Optical Imaging
2015
12 Citations (Scopus)

Surface plasmon resonance analysis of seven-transmembrane receptors

Aristotelous, T., Hopkins, A. L. & Navratilova, I., 2015, Membrane proteins—production and functional characterization. Shukla, A. K. (ed.). Academic Press, p. 499-525 27 p. (Methods in Enzymology; vol. 556).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Surface Plasmon Resonance
Surface plasmon resonance
Ligands
G-Protein-Coupled Receptors
Screening
2014
2 Citations (Scopus)

Structure-based virtual screening for the identification of RNA-binding ligands

Daldrop, P. & Brenk, R., 2014, Therapeutic applications of ribozymes and riboswitches: methods and protocols. Lafontaine, D. & Dubé, A. (eds.). Humana Press, p. 127-139 13 p. (Methods in Molecular Biology; vol. 1103).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

RNA
Ligands
Software
Proteins
2013
36 Citations (Scopus)

Biophysical screening for the discovery of small-molecule ligands

Ciulli, A., 2013, Protein-ligand interactions: methods and applications. Williams, M. A. & Daviter, T. (eds.). Humana Press, p. 357-388 32 p. (Methods in Molecular Biology; vol. 1008).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Ligands
Fluorometry
Calorimetry
Proteins
Fluorescence Polarization
6 Citations (Scopus)

Creation and characterization of glycosyltransferase mutants of trypanosoma brucei

Izquierdo, L., Güther, M. L. S. & Ferguson, M. A. J., 2013, Glycosyltransferases. Brockhausen, I. (ed.). Humana Press, p. 249-275 27 p. (Methods in Molecular Biology; vol. 1022).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Glycosyltransferases
Trypanosoma brucei brucei
Glycoconjugates
Life Cycle Stages
Parasites
2012

The structure and folding of helical junctions in RNA

Lilley, D. M. J., 2012, Innovations in Biomolecular Modeling and Simulations. Schlick, T. (ed.). Cambridge: Royal Society of Chemistry, (RSC Biomolecular Sciences).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

2007
1 Citation (Scopus)

Proteins interacting with Saccharomyces cerevisiae type 1 protein phosphatase catalytic subunit identified by single-step affinity purification and mass spectrometry

Walsh, E. P., Lamont, D., Beattie, K. A. & Stark, M. J. R., 2007, Protein phosphatase protocols. Moorhead, G. (ed.). Humana Press, p. 235-246 12 p. (Methods in Molecular Biology; vol. 365).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Saccharomyces cerevisiae Proteins
Phosphoprotein Phosphatases
Mass Spectrometry
Catalytic Domain
Yeasts
1999
9 Citations (Scopus)

Analysis of the carbohydrate components of glycosylphosphatidylinositol structures using fluorescent labeling

Zitzmann, N. & Ferguson, M. A. J., 1999, Protein lipidation protocols . Gelb, M. H. (ed.). Totowa: Humana Press, p. 73-89 17 p. (Methods in Molecular Biology; vol. 116).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Glycosylphosphatidylinositols
Labeling
Carbohydrates
Inositol
Phospholipids
1998
12 Citations (Scopus)

Analysis of the carbohydrate and lipid components of glycosylphosphatidylinositol structures

Treumann, A., Güther, M. L., Schneider, P. & Ferguson, M. A. J., 1998, Glycoanalysis protocols . Hounsell, E. F. (ed.). Totowa: Humana Press, p. 213-235 23 p. (Methods in Molecular Biology; vol. 76).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Glycosylphosphatidylinositols
Carbohydrates
Lipids
Inositol
Phospholipids
1995
50 Citations (Scopus)

Microscale analysis of glycosylphosphatidylinositol structures

Schneider, P. & Ferguson, M. A. J., 1995, Lipid modifications of proteins. Casey, P. J. & Buss, J. E. (eds.). Academic Press, p. 614-630 17 p. (Methods in Enzymology; vol. 250).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

1993
8 Citations (Scopus)

The microanalysis of glycosyl-phosphatidylinositol glycans

Güther, M. L. & Ferguson, M. A. J., 1993, Glycoprotein analysis in biomedicine . Hounsell, E. F. (ed.). Totowa: Humana Press, p. 99-117 19 p. (Methods in Molecular Biology; vol. 14).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)