Biological Chemistry and Drug Discovery

  • United Kingdom

Research Output 1972 2020

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Meeting abstract
2017

Early stages of Parkin activation - A computational study

Carvalheda Dos Santos, C., Bueren-Calabuig, J., Kumar, A., Walden, H. & Pisliakov, A., 2017, In : European Biophysics Journal. 46, Suppl 1, p. S155 1 p., P-154.

Research output: Contribution to journalMeeting abstract

Mitochondrial Degradation
Phosphorylation
Allosteric Regulation
Ubiquitin-Conjugating Enzymes
Mutation
2014
56 Downloads (Pure)

ChemicalToolBoX and its application on the study of the drug like and purchasable space

Lucas, X., Grüning, B. A. & Günther, S., 11 Mar 2014, In : Journal of Cheminformatics. 6, Suppl. 1, 1 p., P51.

Research output: Contribution to journalMeeting abstract

Open Access
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2013

A nonsense mutation in the mattrin gene causes the matted mouse phenotype and is a predisposing gene for atopic dermatitis in humans

Goh, C. S., Saunders, S. P., Cole, C., Weidinger, S., Baurecht, H., Lee, Y., Reynolds, N. J., Barker, J. N., Cordell, H. J., Brown, S. J., Irvine, A. D., McLean, I., Sandilands, A. & Fallon, P. G., 2013, In : Journal of Investigative Dermatology. 133, S1, p. S145 1 p., 854.

Research output: Contribution to journalMeeting abstract

2011

Drug discovery initiative at the University of Dundee: hit-to-lead development for hat and generation of chemical tools

Grimaldi, R., Urich, R., Sienkiewicz, N., Woodland, A., Urbaniak, M. D., Mathieson, T., Eberhard, D., Bantscheff, M., Drewes, G., Ferguson, M. A. J., Gilbert, I. H., Frearson, J. A., Wyatt, P. G. & Fairlamb, A. H., 2011, In : Tropical Medicine & International Health. 16, S.1, p. 212 1 p., 1.3-148.

Research output: Contribution to journalMeeting abstract

On the hunt for new diagnostic antigens for human African trypanosomiasis

Sullivan, L., Carrington, M. & Ferguson, M. A. J., Oct 2011, In : Tropical Medicine & International Health. 16, p. 201-201 1 p.

Research output: Contribution to journalMeeting abstract

2010

Glycoinositolphosphorylceramide from Pathogenic Fungus Sporothrix schenckii Shows That Fatty Acid Hydroxylation Level Correlates with the Mycelium-Yeast Thermal-Induced Morphological Transition

Medeiros, A., Bandini, G., Macedo, C., Ferguson, M., Kirsch, S., Soltwisch, J., Previato, J., Mendonca-Previato, L. & Peter-Katalinic, J., Nov 2010, In : Glycobiology. 20, 11, p. 1506-1506 1 p.

Research output: Contribution to journalMeeting abstract

2009

A requirement for GDP-L-fucose in Leishmania inferred by rescue of D-arabinopyranose/L-fucose salvage mutants (Fkp40(-)/Afkp80(-)) by expression of GDP-L-fuc synthetic enzymes

Guo, H., Novozhilova, N. M., Bandini, G., Notton, T., Turco, S. J., Ferguson, M. A. J. & Beverley, S. M., Nov 2009, In : Glycobiology. 19, 11, p. 1297-1297 1 p.

Research output: Contribution to journalMeeting abstract

How does human O-Glcnacase recognize O-Glcnacylated protein substrates?

Schimpl, M., Borodkin, V. S. & Van Aalten, D. M. F., 2009, In : Glycobiology. 19, 11, p. 1369-1369 1 p., 272.

Research output: Contribution to journalMeeting abstract

Preferential Activation of TLR2/6 Heterodimer by Synthetic Trypanosoma Cruzi Trypomastigote Glycosylphosphatidylinositols is Enhanced by Coexpression of CD14 and CD36

Nohara, L., Yashunsky, D., Ferguson, M., Nikolaev, A. & Almeida, I., Nov 2009, In : Glycobiology. 19, 11, p. 1361-1361 1 p., 247.

Research output: Contribution to journalMeeting abstract

2008

Sugar nucleotide metabolism and compartmentation in Trypanosoma brucei: new insights from UDP-GlcNAc and UDP-Glc biosynthesis

Marino, K., Guther, M. L. S. & Ferguson, M., Nov 2008, In : Glycobiology. 18, 11, p. 946-946 1 p.

Research output: Contribution to journalMeeting abstract

2006

The proteome of Trypanosoma cruzi shed vesicles involved in host immuno modulation and cell invasion

Nakayasu, E. S., Torrecilhas, A. C. T., Gozzo, F., Nohara, L. L., Lamont, D., Alves, M. J. M., Ferguson, M. A. J. & Almeida, I. C., 2006, In : FASEB Journal. 20, 4, p. A514-A514 1 p., 346.5.

Research output: Contribution to journalMeeting abstract

2003

Species specific inhibitors of glycosylphosphatidylinositol anchor biosynthesis that target trypanosoma brucei, the causative agent of African Sleeping Sickness

Urbaniak, M. D., Smith, T. K., Crossman, A., Chang, T. & Ferguson, M. A. J., Nov 2003, In : Glycobiology. 13, 11, p. 877-878 2 p.

Research output: Contribution to journalMeeting abstract

2001

New parasite-specific inhibitors of GPI anchor biosynthesis.

Smith, T. K., Crossman, A., Borissow, C. N., Paterson, M. J., Dix, A. P., Brimacombe, J. S. & Ferguson, M. A. J., 2001, In : Glycobiology. 11, 10 (Supplement), p. 870-870 1 p.

Research output: Contribution to journalMeeting abstract

2000

Cloning, complementation and expression of UDP glucose 4 ' epimerase from Trypanosoma brucei and T-cruzi

Roper, J. R., Milne, K. G., Guther, M. L. S. & Ferguson, M. A. J., Oct 2000, In : Glycobiology. 10, 10 (Supplement), p. 1124-1124 1 p.

Research output: Contribution to journalMeeting abstract

Synthesis of aminoacids derivatives as Rev-RRE binding inhibitors, using solid phase combinatorial chemistry

Jimenez-Bueno, G., Simons, C. & Gilbert, I. H., 2000, In : Antiviral Research. 46, 1, p. A43-A43 1 p., 26.

Research output: Contribution to journalMeeting abstract

1999

Glycoform analysis of a Trypanosoma brucei class III variant surface glycoprotein (VSG) by MALDI-TOF

Mehlert, A. & Ferguson, M. A. J., 1999, In : Glycobiology. 9, 10, p. 1151-1152 2 p.

Research output: Contribution to journalMeeting abstract

The structure of novel phosphosaccharide glycans of Trypanosoma cruzi

Allen, S., Mehlert, A. & Ferguson, M. A. J., 1999, In : Biochemical Society Transactions. 27, 3, p. A111 1 p., 72.

Research output: Contribution to journalMeeting abstract

1998

Regulation of yeast Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p

Sassoon, I., Taba-Casari, M. R., Severin, F. F., Andrews, P. D., Kaplan, K. B., Stark, M. J. R., Sorger, P. K. & Hyman, A. A., Nov 1998, In : Molecular Biology of the Cell. 9, Supple., p. 281A-281A 1 p.

Research output: Contribution to journalMeeting abstract

The structural basis of ConA-resistance in Trypanosoma brucei glycosylation mutants

Acosta-Serrano, A., Mehlert, A., Ferguson, M. A. J. & Englund, P. T., 1998, In : Glycobiology. 8, 11, p. 1106-1107 2 p.

Research output: Contribution to journalMeeting abstract

1997
72 Citations (Scopus)

Biosynthesis of GPI-anchored proteins

Ferguson, M. A. J., 1997, In : FASEB Journal. 11, 9, p. A859-A859 1 p.

Research output: Contribution to journalMeeting abstract

Primary and three dimensional structure of the type II VSG GPI anchor

Richardson, J. M., Mehlert, A. & Ferguson, M. A. J., 1997, In : Biochemical Society Transactions. 25, 4, p. S664-S664 1 p.

Research output: Contribution to journalMeeting abstract