Biological Chemistry and Drug Discovery

Research output

Research output per year 1972 2005 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025

• 147190 Citations
• 156 h-index
• 1731 Article
• 114 Review article
• 31 Letter
• 30 Chapter
• 203 More
  • 28 Meeting abstract
  • 26 Chapter (peer-reviewed)
  • 26 Comment/debate
  • 26 Editorial
  • 15 Patent
  • 14 Conference contribution
  • 12 Book/Film/Article review
  • 11 Other contribution
  • 9 Preprint
  • 7 Other report
  • 4 Short survey
  • 4 Exhibition
  • 3 Abstract
  • 3 Digital or Visual Products
  • 2 Foreword/postscript
  • 2 Paper
  • 2 Poster
  • 2 Conference article
  • 2 Special issue
  • 1 Book
  • 1 Entry for encyclopedia/dictionary
  • 1 Artefact
  • 1 Exhibition catalogue
  • 1 Software

Research output per year

Research output per year

Search results

• 2024

  Preliminary assessment of microneedle wound healing in a full-thickness ex vivo human skin model cultured at physiological tension

  Campbell, P., Hickerson, R., Conneely, M., Grussu, D., Tsutsumi, S. K. H., Prausnitz, M. & Azizoglu, G., 1 Aug 2024, In: Journal of Investigative Dermatology. 144, 8, p. 185 1 p., S185.

  Research output: Contribution to journal › Meeting abstract › peer-review

  • Wound Healing 100%
  • Full-thickness 100%
  • In Vitro Skin Model 100%
  • Microneedles 100%
  • Wound 100%
• 2023

  Discovery of new E3 ligases for alpha-synuclein clearance

  Kocaturk, N. (Lead / Corresponding author), Li, Z., Ganley, I. & Sapkota, G. P., 28 Jun 2023, In: Journal of Parkinson's Disease. 13, S1, p. 74 1 p., P03.05.

  Research output: Contribution to journal › Meeting abstract › peer-review

  Open Access

  • E3 Ligase 100%
  • Alpha-synuclein (α-syn) 100%
  • Ligase 100%
  • Alpha-Synuclein 100%
  • Parkinson's Disease 60%

• Mechanical tension influences the immunocompetency of ex vivo skin tissue

  Hickerson, R., Grussu, D., Tsutsumi, K., Campbell, P. & Conneely, M., 31 May 2023, In: Journal of Investigative Dermatology. 143, 5, p. S180 1 p., 1053.

  Research output: Contribution to journal › Meeting abstract › peer-review

  • Skin Tissue 100%
  • Ex Vivo Human Skin 100%
  • Mechanical Tension 100%
  • Immunocompetency 100%
  • Ex Vivo 100%

• ‘Exchanges’: A visual resource to inspire and support deeper conversations in the Parkinson’s community

  Muqit, M., Patel, D., Patrick, S., Kocaturk, N., Saarela, D., Agarwal, S., Shi, G., Carton, B., Niven, J., Wreford, K., Lawson, D., Keir, I., Langlands, S., Donegan, L., Knowles, A., Knowles, S., Milne, J., Giddens, T. & Davies, P., 28 Jun 2023, In: Journal of Parkinson's Disease. 13, S1, p. 348 1 p., P45.32.

  Research output: Contribution to journal › Meeting abstract › peer-review

  Open Access

  • Parkinson 100%
  • Visual Resources 100%
  • Lived Experience 100%
  • Valuable Resource 50%
  • Research Process 50%
• 2020

  Investigating the role of protein S-glutathionylation in sFlt-1 regulation and preeclampsia phenotype

  Lermant, A., Sneddon, C., Hanna, J., Markwalder, L. & Murdoch, C., 5 Apr 2020, In: Heart. 106, Suppl 1, p. A7 1 p., P4.

  Research output: Contribution to journal › Meeting abstract › peer-review

  • Preeclampsia 100%
  • S-glutathionylation 100%
  • Soluble Fms-like Tyrosine kinase-1 (sFlt-1) 100%
  • Protein S 100%
  • S-Glutathionylation 100%
• 2019

  IDENTIFICATION OF THE PLASMODIUM FALCIPARUM ACETYL-COA SYNTHETASE AS AN EMERGING ANTIPLASMODIAL DRUG TARGET

  Summers, R. L., Vanaerschot, M., Murithi, J. M., Pasaje, C. F., Luth, M. R., Magistrado-Coxen, P., Carpenter, E. F., Bath, J., Pisco, J. P., Punekar, A. S., Baragana, B., Gilbert, I. H., Munro, J. T., Llinas, M., Niles, J. C., Ottilie, S., Winzeler, E. A., Lee, M. C., Fidock, D. A. & Lukens, A. K. & 1 others, Wirth, D. F., Nov 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 5_Suppl, p. 476-477 2 p., 1555.

  Research output: Contribution to journal › Meeting abstract › peer-review
  2 Citations (Scopus)
• 2017

  Early stages of Parkin activation - A computational study

  Carvalheda Dos Santos, C., Bueren-Calabuig, J., Kumar, A., Walden, H. & Pisliakov, A., 2017, In: European Biophysics Journal. 46, Suppl 1, p. S155 1 p., P-154.

  Research output: Contribution to journal › Meeting abstract

  Open Access

  • Computational Study 100%
  • Parkin 100%
  • Conformation 100%
  • Ubiquitin-Conjugating Enzyme 100%
  • Allosteric Regulation 50%

• Molecular details of RNA methyltransferase activity and allosteric regulation: A simulation study

  Bueren-Calabuig, J., Bage, M., Cowling, V. & Pisliakov, A., 2017, In: European Biophysics Journal. 46, Suppl 1, p. S154 1 p., P-151.

  Research output: Contribution to journal › Meeting abstract

  Open Access
• 2014

  ChemicalToolBoX and its application on the study of the drug like and purchasable space

  Lucas, X. (Lead / Corresponding author), Grüning, B. A. & Günther, S., 11 Mar 2014, In: Journal of Cheminformatics. 6, Suppl. 1, 1 p., P51.

  Research output: Contribution to journal › Meeting abstract › peer-review

  Open Access

  File
  165 Downloads (Pure)
• 2013

  A nonsense mutation in the mattrin gene causes the matted mouse phenotype and is a predisposing gene for atopic dermatitis in humans

  Goh, C. S., Saunders, S. P., Cole, C., Weidinger, S., Baurecht, H., Lee, Y., Reynolds, N. J., Barker, J. N., Cordell, H. J., Brown, S. J., Irvine, A. D., McLean, I., Sandilands, A. & Fallon, P. G., 2013, In: Journal of Investigative Dermatology. 133, S1, p. S145 1 p., 854.

  Research output: Contribution to journal › Meeting abstract › peer-review
• 2011

  Drug discovery initiative at the University of Dundee: hit-to-lead development for hat and generation of chemical tools

  Grimaldi, R., Urich, R., Sienkiewicz, N., Woodland, A., Urbaniak, M. D., Mathieson, T., Eberhard, D., Bantscheff, M., Drewes, G., Ferguson, M. A. J., Gilbert, I. H., Frearson, J. A., Wyatt, P. G. & Fairlamb, A. H., 2011, In: Tropical Medicine & International Health. 16, S.1, p. 212 1 p., 1.3-148.

  Research output: Contribution to journal › Meeting abstract › peer-review

• On the hunt for new diagnostic antigens for human African trypanosomiasis

  Sullivan, L., Carrington, M. & Ferguson, M. A. J., Oct 2011, In: Tropical Medicine & International Health. 16, p. 201-201 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review
• 2010

  Glycoinositolphosphorylceramide from Pathogenic Fungus Sporothrix schenckii Shows That Fatty Acid Hydroxylation Level Correlates with the Mycelium-Yeast Thermal-Induced Morphological Transition

  Medeiros, A., Bandini, G., Macedo, C., Ferguson, M., Kirsch, S., Soltwisch, J., Previato, J., Mendonca-Previato, L. & Peter-Katalinic, J., Nov 2010, In: Glycobiology. 20, 11, p. 1506-1506 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review
• 2009

  A requirement for GDP-L-fucose in Leishmania inferred by rescue of D-arabinopyranose/L-fucose salvage mutants (Fkp40(-)/Afkp80(-)) by expression of GDP-L-fuc synthetic enzymes

  Guo, H., Novozhilova, N. M., Bandini, G., Notton, T., Turco, S. J., Ferguson, M. A. J. & Beverley, S. M., Nov 2009, In: Glycobiology. 19, 11, p. 1297-1297 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• How does human O-Glcnacase recognize O-Glcnacylated protein substrates?

  Schimpl, M., Borodkin, V. S. & Van Aalten, D. M. F., 2009, In: Glycobiology. 19, 11, p. 1369-1369 1 p., 272.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Preferential Activation of TLR2/6 Heterodimer by Synthetic Trypanosoma Cruzi Trypomastigote Glycosylphosphatidylinositols is Enhanced by Coexpression of CD14 and CD36

  Nohara, L., Yashunsky, D., Ferguson, M., Nikolaev, A. & Almeida, I., Nov 2009, In: Glycobiology. 19, 11, p. 1361-1361 1 p., 247.

  Research output: Contribution to journal › Meeting abstract › peer-review
• 2008

  Sugar nucleotide metabolism and compartmentation in Trypanosoma brucei: new insights from UDP-GlcNAc and UDP-Glc biosynthesis

  Marino, K., Guther, M. L. S. & Ferguson, M., Nov 2008, In: Glycobiology. 18, 11, p. 946-946 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review
• 2006

  The proteome of Trypanosoma cruzi shed vesicles involved in host immuno modulation and cell invasion

  Nakayasu, E. S., Torrecilhas, A. C. T., Gozzo, F., Nohara, L. L., Lamont, D., Alves, M. J. M., Ferguson, M. A. J. & Almeida, I. C., 2006, In: FASEB Journal. 20, 4, p. A514-A514 1 p., 346.5.

  Research output: Contribution to journal › Meeting abstract › peer-review
• 2003

  Species specific inhibitors of glycosylphosphatidylinositol anchor biosynthesis that target trypanosoma brucei, the causative agent of African Sleeping Sickness

  Urbaniak, M. D., Smith, T. K., Crossman, A., Chang, T. & Ferguson, M. A. J., Nov 2003, In: Glycobiology. 13, 11, p. 877-878 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review
• 2001

  New parasite-specific inhibitors of GPI anchor biosynthesis.

  Smith, T. K., Crossman, A., Borissow, C. N., Paterson, M. J., Dix, A. P., Brimacombe, J. S. & Ferguson, M. A. J., 2001, In: Glycobiology. 11, 10 (Supplement), p. 870-870 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review
• 2000

  Cloning, complementation and expression of UDP glucose 4 ' epimerase from Trypanosoma brucei and T-cruzi

  Roper, J. R., Milne, K. G., Guther, M. L. S. & Ferguson, M. A. J., Oct 2000, In: Glycobiology. 10, 10 (Supplement), p. 1124-1124 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Synthesis of aminoacids derivatives as Rev-RRE binding inhibitors, using solid phase combinatorial chemistry

  Jimenez-Bueno, G., Simons, C. & Gilbert, I. H., 2000, In: Antiviral Research. 46, 1, p. A43-A43 1 p., 26.

  Research output: Contribution to journal › Meeting abstract › peer-review
• 1999

  Glycoform analysis of a Trypanosoma brucei class III variant surface glycoprotein (VSG) by MALDI-TOF

  Mehlert, A. & Ferguson, M. A. J., 1999, In: Glycobiology. 9, 10, p. 1151-1152 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• The structure of novel phosphosaccharide glycans of Trypanosoma cruzi

  Allen, S., Mehlert, A. & Ferguson, M. A. J., 1999, In: Biochemical Society Transactions. 27, 3, p. A111 1 p., 72.

  Research output: Contribution to journal › Meeting abstract › peer-review
• 1998

  Regulation of yeast Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p

  Sassoon, I., Taba-Casari, M. R., Severin, F. F., Andrews, P. D., Kaplan, K. B., Stark, M. J. R., Sorger, P. K. & Hyman, A. A., Nov 1998, In: Molecular Biology of the Cell. 9, Supple., p. 281A-281A 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• The structural basis of ConA-resistance in Trypanosoma brucei glycosylation mutants

  Acosta-Serrano, A., Mehlert, A., Ferguson, M. A. J. & Englund, P. T., 1998, In: Glycobiology. 8, 11, p. 1106-1107 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review
• 1997

  Biosynthesis of GPI-anchored proteins

  Ferguson, M. A. J., 1997, In: FASEB Journal. 11, 9, p. A859-A859 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review
  79 Citations (Scopus)

• Primary and three dimensional structure of the type II VSG GPI anchor

  Richardson, J. M., Mehlert, A. & Ferguson, M. A. J., 1997, In: Biochemical Society Transactions. 25, 4, p. S664-S664 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review