Research Output per year
Research Output 1984 2020
- 1 - 50 out of 172 results
- Title (ascending)
(+)-Pinoresinol/(+)-lariciresinol reductase from Forsythia intermedia: Protein purification, cDNA cloning, heterologous expression and comparison to isoflavone reductase
Dinkova-Kostova, A. T., Gang, D. R., Davin, L. B., Bedgar, D. L., Chu, A. & Lewis, N. G., 26 Nov 1996, In : Journal of Biological Chemistry. 271, 46, p. 29473-29482 10 p.Research output: Contribution to journal › Article
A comparative pharmacokinetic study of PARP inhibitors demonstrates favorable properties for niraparib efficacy in preclinical tumor models
Sun, K., Mikule, K., Wang, Z., Poon, G., Vaidyanathan, A., Smith, G., Zhang, Z. Y., Hanke, J., Ramaswamy, S. & Wang, J., 14 Dec 2018, In : Oncotarget. 9, 98, p. 37080-37096 17 p.Research output: Contribution to journal › Article
Acute effects of electronic and tobacco cigarettes on vascular and respiratory function in healthy volunteers: a cross-over study
Kerr, D. M. I., Brooksbank, K. J. M., Taylor, R. G., Pinel, K., Rios, F. J., Touyz, R. M. & Delles, C., Jan 2019, In : Journal of Hypertension. 37, 1, p. 154-166 13 p.Research output: Contribution to journal › Article
A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia
Baardman, J., Verberk, S. G. S., Prange, K. H. M., van Weeghel, M., van der Velden, S., Ryan, D. G., Wüst, R. C. I., Neele, A. E., Speijer, D., Denis, S. W., Witte, M. E., Houtkooper, R. H., O'neill, L. A., Knatko, E. V., Dinkova-Kostova, A. T., Lutgens, E., de Winther, M. P. J. & Van den Bossche, J., 20 Nov 2018, In : Cell Reports. 25, 8, p. 2044-2052.e5 15 p.Research output: Contribution to journal › Article
Adenosine Monophosphate-Activated Protein Kinase: Hydroxymethylglutaryl-CoA Reductase Kinase
Carling, D., Clarke, P. R. & Hardie, D. G., 1 Jan 1991, In : Methods in Enzymology. 200, C, p. 362-371 10 p.Research output: Contribution to journal › Article
A gradient signal orchestrates the mitotic spindle
Clarke, P. R., 26 Aug 2005, In : Science. 309, 5739, p. 1334-1335 2 p.Research output: Contribution to journal › Review article
Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress
Muqit, M. M. K., Abou-Sleiman, P. M., Saurin, A. T., Harvey, K., Gandhi, S., Deas, E., Eaton, S., Payne Smith, M. D., Venner, K., Matilla, A., Healy, D. G., Gilks, W. P., Lees, A. J., Holton, J., Revesz, T., Parker, P. J., Harvey, R. J., Wood, N. W. & Latchman, D. S., Jul 2006, In : Journal of Neurochemistry. 98, 1, p. 156-169 14 p.Research output: Contribution to journal › Article
Analysis of the genomic l rna segment from lymphocytic choriomeningitis virus
Singh, M. K., Fuller-Pace, F. V., Buchmeier, M. J. & Southern, P. J., 1 Dec 1987, In : Virology. 161, 2, p. 448-456 9 p.Research output: Contribution to journal › Article
Anchoring RCC1 by the tail
Clarke, P. R., 1 May 2007, In : Nature Cell Biology. 9, 5, p. 485-487 3 p.Research output: Contribution to journal › Article
Apoptosis: Does stress kill?
Cosulich, S. & Clarke, P., 1 Jan 1996, In : Current Biology. 6, 12, p. 1586-1588 3 p.Research output: Contribution to journal › Article
Are baseline ultrasound and mammographic features associated with rates of pathological completes response in patients receiving neoadjuvant chemotherapy for breast cancer?
Savaridas, S. L., Sim, Y. T., Vinnicombe, S. J., Purdie, C. A., Thompson, A. M. & Evans, A., 21 Oct 2019, In : Cancer Imaging. 19, 1, p. 1-7 7 p., 67.Research output: Contribution to journal › Article
Atypical APC/C-dependent degradation of Mcl-1 provides an apoptotic timer during mitotic arrest
Allan, L. A., Skowyra, A., Rogers, K. I., Zeller, D. & Clarke, P. R., 3 Sep 2018, In : The EMBO Journal. 37, 17, p. 1-15 15 p., e96831.Research output: Contribution to journal › Article
Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Nik-Zainal, S., Davies, H., Staaf, J., Ramakrishna, M., Glodzik, D., Zou, X., Martincorena, I., Alexandrov, L. B., Martin, S., Wedge, D. C., Van Loo, P., Ju, Y. S., Smid, M., Brinkman, A. B., Morganella, S., Aure, M. R., Lingjærde, O. C., Langerød, A., Ringnér, M., Ahn, S-M. & 68 others, , 7 Feb 2019, In : Nature. 566, 7742, p. E1 1 p.Research output: Contribution to journal › Article
Azathioprine: friend or foe?
Leigh, I. M., Proby, C. M., Inman, G. J. & Harwood, C. A., May 2019, In : British Journal of Dermatology. 180, 5, p. 961-963 3 p.Research output: Contribution to journal › Editorial
Bcl-2 regulates a caspase-3/caspase-2 apoptotic cascade in cytosolic extracts
Swanton, E., Savory, P., Cosulich, S., Clarke, P. & Woodman, P., 11 Mar 1999, In : Oncogene. 18, 10, p. 1781-1787 7 p.Research output: Contribution to journal › Article
Bcl-2 regulates activation of apoptotic proteases in a cell-free system
Cosulich, S. C., Green, S. & Clarke, P. R., 1 Aug 1996, In : Current Biology. 6, 8, p. 997-1005 9 p.Research output: Contribution to journal › Article
Bcl-2 regulates amplification of caspase activation by cytochrome c
Cosulich, S. C., Savory, P. J. & Clarke, P. R., 11 Feb 1999, In : Current Biology. 9, 3, p. 147-150 4 p.Research output: Contribution to journal › Article
Bis(2-hydroxybenzylidene)acetone, a potent inducer of the phase 2 response, causes apoptosis in mouse leukemia cells through a p53-independent, caspase-mediated pathway
Dinkova-Kostova, A. T., Cory, A. H., Bozak, R. E., Hicks, R. J. & Cory, J. G., 8 Jan 2007, In : Cancer Letters. 245, 1-2, p. 341-349 9 p.Research output: Contribution to journal › Article
Broccoli or Sulforaphane: Is It the Source or Dose That Matters?
Yagishita, Y., Fahey, J. W., Dinkova-Kostova, A. T. & Kensler, T. W., 6 Oct 2019, In : Molecules and Cells. 24, 19, p. 1-38 38 p., 3593.Research output: Contribution to journal › Review article
Calmodulin-dependent multiprotein kinase and protein kinase C phosphorylate the same site on HMG-CoA reductase as the AMP-activated protein kinase
Clarke, P. R. & Grahame Hardie, D., 20 Aug 1990, In : FEBS Letters. 269, 1, p. 213-217 5 p.Research output: Contribution to journal › Article
Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1
Casares Perez, L., García, V., Garrido-Rodríguez, M., Millán, E., Collado, J. A., García-Martín, A., Peñarando, J., Calzado, M. A., de la Vega, L. & Muñoz, E., 5 Sep 2019, In : Redox Biology. 28, p. 1-15 15 p., 101321.Research output: Contribution to journal › Article
cdc25‐C is ACTIVATED BY PHOSPHORYLATION AT MITOSIS
Hoffmann, I., Clarke, P., Karsenti, E. & Draetta, G., 1 Jan 1992, In : Biology of the Cell. 76, 2, p. 213 1 p.Research output: Contribution to journal › Article
Cell Biology: Ran, Mitosis and the Cancer Connection
Sanderson, H. S. & Clarke, P. R., 20 Jun 2006, In : Current Biology. 16, 12, p. R466-R468 3 p.Research output: Contribution to journal › Short survey
Chemical Structures of Inducers of Nicotinamide Quinone Oxidoreductase 1 (NQO1)
Dinkova-Kostova, A. T., Fahey, J. W. & Talalay, P., 2004, In : Methods in Enzymology. 382, p. 423-448 26 p.Research output: Contribution to journal › Article
Chemoprotection against cancer: An idea whose time has come
Dinkova-Kostova, A. T., 1 Mar 2007, In : Alternative Therapies in Health and Medicine. 13, 2, p. S122-S127Research output: Contribution to journal › Article
Chemoprotective properties of phenylpropenoids, bis(benzylidene)cycloalkanones, and related Michael reaction acceptors: Correlation of potencies as phase 2 enzyme inducers and radical scavengers
Dinkova-Kostova, A. T., Abeygunawardana, C. & Talalay, P., 17 Dec 1998, In : Journal of Medicinal Chemistry. 41, 26, p. 5287-5296 10 p.Research output: Contribution to journal › Article
Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes
Fahey, J. W., Stephenson, K. K., Dinkova-Kostova, A. T., Egner, P. A., Kensler, T. W. & Talalay, P., 1 Jul 2005, In : Carcinogenesis. 26, 7, p. 1247-1255 9 p.Research output: Contribution to journal › Article
Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts
Zhang, C. & Clarke, P. R., 26 May 2000, In : Science. 288, 5470, p. 1429-1432 4 p.Research output: Contribution to journal › Article
Cleavage and inactivation of DNA-dependent protein kinase catalytic subunit during apoptosis in Xenopus egg extracts
Le Romancer, M., Cosulich, S. C., Jackson, S. P. & Clarke, P. R., 1 Dec 1996, In : Journal of Cell Science. 109, 13, p. 3121-3127 7 p.Research output: Contribution to journal › Article
Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway
Clarke, C. A. L., Bennett, L. N. & Clarke, P. R., 21 Oct 2005, In : Journal of Biological Chemistry. 280, 42, p. 35337-35345 9 p.Research output: Contribution to journal › Article
Cleavage of Rabaptin-5 blocks endosome fusion during apoptosis
Cosulich, S. C., Horiuchi, H., Zerial, M., Clarke, P. R. & Woodman, P. G., 5 Nov 1997, In : EMBO Journal. 16, 20, p. 6182-6191 10 p.Research output: Contribution to journal › Article
Cloning and fnctional expression of an apparent splice variant of the murine 5-HT3 receptor A subunit
Hope, A. G., Downie, D. L., Sutherland, L. A., Lambert, J. J., Peters, J. A. & Burchell, B., 15 Apr 1993, In : European Journal of Pharmacology: Molecular Pharmacology. 245, 2, p. 187-192 6 p.Research output: Contribution to journal › Article
Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly
Zhang, C., Golderg, M. W., Moore, W. J., Allen, T. D. & Clarke, P. R., 1 Nov 2002, In : European Journal of Cell Biology. 81, 11, p. 623-633 11 p.Research output: Contribution to journal › Review article
Correction: The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth
Hanson, K., Robinson, S. D., Al-Yousuf, K., Hendry, A. E., Sexton, D. W., Sherwood, V. & Wheeler, G. N., 27 Nov 2018, In : Oncotarget. 9, 93, p. 36645 1 p.Research output: Contribution to journal › Article
Cutaneous immunohistochemical staining pattern of p53β isoforms
Ko, C. J., Myung, P., Leffell, D. J. & Bourdon, J-C., Dec 2018, In : Journal of Clinical Pathology. 71, 12, p. 1120-1122 3 p.Research output: Contribution to journal › Article
Cyclin-Dependent Kinases: CAK-handed kinase activation
Clarke, P. R., 1 Jan 1995, In : Current Biology. 5, 1, p. 40-42 3 p.Research output: Contribution to journal › Article
Cytoprotective Effects of Dinitrosyl Iron Complexes on Viability of Human Fibroblasts and Cardiomyocytes
Akentieva, N. P., Sanina, N. A., Gizatullin, A. R., Shkondina, N. I., Prikhodchenko, T. R., Shram, S. I., Zhelev, N. & Aldoshin, S. M., 11 Nov 2019, In : Frontiers in Pharmacology. 10, p. 1-10 21 p., 1277.Research output: Contribution to journal › Article
DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia
Legrand, J. M. D., Chan, A-L., La, H. M., Rossello, F. J., Änkö, M-L., Fuller-Pace, F. V. & Hobbs, R. M., 23 May 2019, In : Nature Communications. 10, 1, p. 1-21 21 p., 2278.Research output: Contribution to journal › Article
Deficiency in Protein Tyrosine Phosphatase PTP1B shortens lifespan and leads to development of acute leukemia
Le Sommer, S., Morrice, N., Pesaresi, M., Thompson, D., Vickers, M. A., Murray, G. I., Mody, N., Neel, B. G., Bence, K. K., Wilson, H. M. & Delibegović, M., Jan 2018, In : Cancer Research. 78, 1, p. 75-87 14 p.Research output: Contribution to journal › Article
Delay in development and behavioural abnormalities in the absence of p53 in zebrafish
Elabd, S., Jabeen, N. A., Gerber, V., Peravali, R., Bourdon, J-C., Kancherla, S., Vallone, D. & Blattner, C., 19 Jul 2019, In : PLoS ONE. 14, 7, 18 p., e0220069.Research output: Contribution to journal › Article
Dephosphorylation of cdc25-C by a type-2A protein phosphatase: Specific regulation during the cell cycle in Xenopus egg extracts
Clarke, P. R., Hoffmann, I., Draetta, G. & Karsenti, E., 1 Apr 1993, In : Molecular Biology of the Cell. 4, 4, p. 397-411 15 p.Research output: Contribution to journal › Article
Dephosphorylation of the inhibitory phosphorylation site S287 in Xenopus Cdc25C by protein phosphatase-2A is inhibited by 14-3-3 binding
Hutchins, J. R. A., Dikovskaya, D. & Clarke, P. R., 25 Sep 2002, In : FEBS Letters. 528, 1-3, p. 267-271 5 p.Research output: Contribution to journal › Article
Detection of virus-specific RNA-dependent RNA polymerase activity in extracts from cells infected with lymphocytic choriomeningitis virus: in vitro synthesis of full-length viral RNA species
Fuller-Pace, F. V. & Southern, P. J., 1 May 1989, In : Journal of Virology. 63, 5, p. 1938-1944 7 p.Research output: Contribution to journal › Article
DHX9 Helicase promotes R-loop formation in cells with impaired RNA splicing
Chakraborty, P., Huang, J. & Hiom, K., 19 Oct 2018, In : Nature Communications. 9, 9, p. 1-14 14 p., 4346.Research output: Contribution to journal › Article
Differential expression of secreted factors SOSTDC1 and ADAMTS8 cause pro-fibrotic changes in linear morphoea fibroblasts
Badshah, I. I., Brown, S., Weibel, L., Rose, A., Way, B., Sebire, N., Inman, G., Harper, J., Kinsler, V. & O'Shaughnessy, R., 26 Oct 2018, In : British Journal of Dermatology.Research output: Contribution to journal › Article
Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase
Groom, L. A., Sneddon, A. A., Alessi, D. R., Dowd, S. & Keyse, S. M., 15 Jul 1996, In : EMBO Journal. 15, 14, p. 3621-32 12 p.Research output: Contribution to journal › Article
Discovery and development of Seliciclib. How systems biology approaches can lead to better drug performance
Khalil, H. S., Mitev, V., Vlaykova, T., Cavicchi, L. & Zhelev, N., 20 May 2015, In : Journal of Biotechnology. 202, p. 40-49 10 p.Research output: Contribution to journal › Article
Distribution and diversity of hsd genes in Escherichia coli and other enteric bacteria.
Daniel, A. S., Fuller-Pace, F. V., Legge, D. M. & Murray, N. E., 1 Apr 1988, In : Journal of Bacteriology. 170, 4, p. 1775-1782 8 p.Research output: Contribution to journal › Article
Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation: Evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury during myocardial ischemia
Tanno, M., Bassi, R., Gorog, D. A., Saurin, A. T., Jiang, J., Heads, R. J., Martin, J. L., Davis, R. J., Flavell, R. A. & Marber, M. S., 8 Aug 2003, In : Circulation Research. 93, 3, p. 254-261 8 p.Research output: Contribution to journal › Article
Division of labour between PP2A-B56 isoforms at the centromere and kinetochore
Vallardi, G., Allan, L., Crozier, L. & Saurin, A. T., 4 Mar 2019, In : eLife. 8, p. 1-25 25 p., e42619.Research output: Contribution to journal › Article