Cellular Medicine

Research Output 1984 2020

2018
8 Citations (Scopus)
83 Downloads (Pure)

Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease

Arnoux, I., Willam, M., Griesche, N., Krummeich, J., Watari, H., Offermann, N., Weber, S., Narayan Dey, P., Chen, C., Monteiro, O., Buettner, S., Meyer, K., Bano, D., Radyushkin, K., Langston, R., Lambert, J. J., Wanker, E., Methner, A., Krauss, S., Schweiger, S. & 1 others, Stroh, A., 4 Sep 2018, In : eLife. 7, p. 1-32 32 p., e38744.

Research output: Contribution to journalArticle

Open Access
File
Metformin
Huntington Disease
Animal Behavior
Aberrations
Visual Cortex
5 Citations (Scopus)
99 Downloads (Pure)

Phenethyl isothiocyanate, a dual activator of transcription factors NRF2 and HSF1

Dayalan Naidu, S., Suzuki, T., Yamamoto, M., Fahey, J. W. & Dinkova-Kostova, A., 1 Sep 2018, In : Molecular Nutrition & Food Research. 62, 18, p. e1700908 9 p., 1700908.

Research output: Contribution to journalReview article

Open Access
File
isothiocyanates
heat stress
transcription factors
Vegetables
Glucosinolates
6 Citations (Scopus)
89 Downloads (Pure)

Prediction of Pathological Complete Response to Neoadjuvant Chemotherapy for Primary Breast Cancer Comparing Interim Ultrasound, Shear Wave Elastography and MRI

Evans, A., Whelehan, P., Thompson, A., Purdie, C., Jordan, L., Macaskill, J., Waugh, S., Fuller-Pace, F., Brauer, K. & Vinnicombe, S., Aug 2018, In : European Journal of Ultrasound. 39, 04, p. 422-431 10 p.

Research output: Contribution to journalArticle

Open Access
File
Elasticity Imaging Techniques
Magnetic Resonance Imaging
Breast Neoplasms
Drug Therapy
Sensitivity and Specificity
2 Citations (Scopus)
67 Downloads (Pure)

Pre-operative stromal stiffness measured by shear wave elastography is independently associated with breast cancer specific survival

Evans, A., Sim, Y. T., Pourreyron, C., Thompson, A., Jordan, L., Fleming, D., Purdie, C., Macaskill, J., Vinnicombe, S. & Pharoah, P., 1 Jun 2018, In : Breast Cancer Research and Treatment. 171, 2, p. 383-389 7 p.

Research output: Contribution to journalArticle

Open Access
File
Elasticity Imaging Techniques
Breast Neoplasms
Survival
Biopsy
Neoplasms
1 Citation (Scopus)
59 Downloads (Pure)

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

Ladds, M. J. G. W., Van Leeuwen, I. M. M., Drummond, C. J., Chu, S., Healy, A. R., Popova, G., Pastor Fernández, A., Mollick, T., Darekar, S., Sedimbi, S. K., Nekulova, M., Sachweh, M. C. C., Campbell, J., Higgins, M., Tuck, C., Popa, M., Safont, M. M., Gelebart, P., Fandalyuk, Z., Thompson, A. M. & 26 others, Svensson, R., Gustavsson, A. L., Johansson, L., Färnegårdh, K., Yngve, U., Saleh, A., Haraldsson, M., D'Hollander, A. C. A., Franco, M., Zhao, Y., Håkansson, M., Walse, B., Larsson, K., Peat, E. M., Pelechano, V., Lunec, J., Vojtesek, B., Carmena, M., Earnshaw, W. C., McCarthy, A. R., Westwood, N. J., Arsenian-Henriksson, M., Lane, D. P., Bhatia, R., McCormack, E. & Laín, S., 22 May 2018, In : Nature Communications. 9, 1, p. 2071 2071.

Research output: Contribution to journalArticle

Open Access
File
document markup languages
inhibitors
Publications
Tumors
tumors
4 Citations (Scopus)
9 Downloads (Pure)

The collagen prolyl hydroxylases are bifunctional growth regulators in melanoma

Atkinson, A., Renziehausen, A., Wang, H., Nigro, C. L., Lattanzio, L., Merlano, M., Rao, B., Weir, L., Evans, A., Matin, R., Harwood, C., Szlosarek, P., Pickering, J. G., Fleming, C., Sim, V. R., Li, S., Vasta, J. T., Raines, R. T., Boniol, M., Thompson, A. & 3 others, Proby, C., Crook, T. & Syed, N., 16 Nov 2018, In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

Open Access
File
Prolyl Hydroxylases
Melanoma
Collagen
Growth
Tumors
92 Downloads (Pure)

The effect of experimental hyperoxia on erythrocytes’ oxygen-transport function

Revin, V. V., Gromova, N. V., Revina, E. S., Grunyushkin, I. P., Tychkov, A. Y., Samonova, A. Y., Kukina, A. N., Moskovkin, A. A., Bourdon, J. C. & Zhelev, N., 2018, In : Biotechnology and Biotechnological Equipment. 32, 5, p. 1236-1250 15 p.

Research output: Contribution to journalArticle

Open Access
File
Hyperoxia
Erythrocytes
Oxygen
Erythrocyte Membrane
Ions
21 Citations (Scopus)
94 Downloads (Pure)

The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature

Inman, G. J., Wang, J., Nagano, A., Alexandrov, L. B., Purdie, K. J., Taylor, R. G., Sherwood, V., Thomson, J., Hogan, S., Spender, L. C., South, A. P., Stratton, M., Chelala, C., Harwood, C. A., Proby, C. M. & Leigh, I. M., 10 Sep 2018, In : Nature Communications. 9, 1, p. 1-14 14 p., 3667.

Research output: Contribution to journalArticle

Open Access
File
Azathioprine
Tumors
tumors
signatures
Skin
3 Citations (Scopus)
1 Downloads (Pure)

The role of APETALA1 in petal number robustness

Monniaux, M., Pieper, B., McKim, S. M., Routier-Kierzkowska, A. L., Kierzkowski, D., Smith, R. S. & Hay, A., 18 Oct 2018, In : eLife. 7, p. 1-22 22 p., e39399.

Research output: Contribution to journalArticle

Open Access
File
Nucleic Acid Regulatory Sequences
Arabidopsis
Cardamine
Quantitative Trait Loci
3 Citations (Scopus)
81 Downloads (Pure)

The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions

Purdie, K. J., Proby, C. M., Rizvi, H., Griffin, H., Doorbar, J., Sommerlad, M., Feltkamp, M. C., Van der Meijden, E., Inman, G. J., South, A. P., Leigh, I. M. & Harwood, C. A., 14 Aug 2018, In : Frontiers in Microbiology. 9, 16 p., 1806.

Research output: Contribution to journalArticle

Open Access
File
Polyomavirus
Squamous Cell Carcinoma
Skin
Mutation
Warts
30 Citations (Scopus)
169 Downloads (Pure)

The role of Nrf2 signaling in counteracting neurodegenerative diseases

Dinkova-Kostova, A. T., Kostov, R. V. & Kazantsev, A. G., 1 Oct 2018, In : FEBS Journal. 285, 19, p. 3576-3590 15 p.

Research output: Contribution to journalReview article

Open Access
File
Neurodegenerative diseases
Neurodegenerative Diseases
Antioxidants
Detoxification
NF-E2 Transcription Factor
78 Downloads (Pure)

Timed degradation of Mcl-1 controls mitotic cell death

Clarke, P. R., Allan, L. A. & Skowyra, A., 2 Nov 2018, In : Molecular and Cellular Oncology. 5, 6, p. 1-4 4 p., e1516450.

Research output: Contribution to journalArticle

Open Access
File
Anaphase-Promoting Complex-Cyclosome
Proteasome Endopeptidase Complex
Ubiquitin
Mitosis
Proteolysis
4 Citations (Scopus)
33 Downloads (Pure)
Open Access
File
Cullin Proteins
NF-E2-Related Factor 2
Zinc
Transcription Factors
Switches
2017
4 Citations (Scopus)
68 Downloads (Pure)

Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE-/- mouse model of atherosclerosis with alterations in IL10/AMPKa pathway

Thompson, D., Morrice, N., Grant, L., Le Sommer, S., Ziegler, K., Whitfield, P., Mody, N., Wilson, H. & Delibegovic, M., Jun 2017, In : Molecular Metabolism. 6, 8, p. 845-853

Research output: Contribution to journalArticle

Open Access
File
Non-Receptor Type 1 Protein Tyrosine Phosphatase
Apolipoproteins E
Atherosclerotic Plaques
Interleukin-10
Atherosclerosis
7 Citations (Scopus)
20 Downloads (Pure)

Pharamcological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in LDLR-/- mouse model of atherosclerosis

Thompson, D., Morrice, N., Grant, L., Lees, E. K., Mody, N., Wilson, H. & Delibegovic, M., 29 Sep 2017, In : Clinical Science. 131, 20, p. 2489-2501

Research output: Contribution to journalArticle

Open Access
File
Non-Receptor Type 1 Protein Tyrosine Phosphatase
Atherosclerotic Plaques
Atherosclerosis
Insulin Receptor
Cardiovascular Diseases
2 Citations (Scopus)
83 Downloads (Pure)

Physical and Chemical Processes and the Morphofunctional Characteristics of Human Erythrocytes in Hyperglycaemia

Revin, V. V., Klenova, N. A., Gromova, N. V., Grunyushkin, I. P., Solomadin, I. N., Tychkov, A. Y., Pestryakova, A. A., Sadykhova, A. V., Revina, E. S., Prosnikova, K. V., Bourdon, J-C. & Zhelev, N., 30 Aug 2017, In : Frontiers in Physiology. 8, 606.

Research output: Contribution to journalArticle

Open Access
File
Chemical Phenomena
Physical Phenomena
Hyperglycemia
Hemoglobins
Erythrocytes
9 Downloads (Pure)

Some problems and errors in cytogenetic biodosimetry

Mosse, I., Kilchevsky, A., Nikolova, N. & Zhelev, N., 4 May 2017, In : Biotechnology and Biotechnological Equipment. 31, 3, p. 460-468 9 p.

Research output: Contribution to journalReview article

Open Access
File
Radiation Tolerance
Cytogenetics
Alleles
Binomial Distribution
Interspersed Repetitive Sequences
2016
35 Citations (Scopus)
80 Downloads (Pure)

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

Cammareri, P., Rose, A., Vincent, D. F., Wang, J., Nagano, A., Libertini, S., Ridgway, R. A., Athineos, D., Coates, P. J. ., McHugh, A., Pourreyron, C., Dayal, J., Larsson, J., Weidlich, S., Spender, L., Sapkota, G., Purdie, K. J., Proby, C., Harwood, C. A., Leigh, I. & 9 others, Clevers, H., Barker, N., Karlsson, S., Pritchard, C., Marais, R., Chelala, C., South, A., Sansom, O. J. & Inman, G., 25 Aug 2016, In : Nature Communications. 7, p. 1-7 7 p., 12493.

Research output: Contribution to journalArticle

Open Access
File
stem cells
Stem cells
deactivation
Squamous Cell Carcinoma
Stem Cells
19 Citations (Scopus)
69 Downloads (Pure)

QTL meta-analysis of root traits in Brassica napus under contrasting phosphorus supply in two growth systems

Zhang, Y., Thomas, C. L., Xiang, J., Long, Y., Wang, X., Zou, J., Luo, Z., Ding, G., Cai, H., Graham, N. S., Hammond, J. P., King, G. J., White, P. J., Xu, F., Broadley, M. R., Shi, L. & Meng, J., 14 Sep 2016, In : Scientific Reports. 6, p. 1-12 12 p., 33113.

Research output: Contribution to journalArticle

Open Access
File
Brassica napus
Quantitative Trait Loci
Phosphorus
Meta-Analysis
Growth
7 Citations (Scopus)
8 Downloads (Pure)

Role of membrane lipids in the regulation of erythrocytic oxygen-transport function in cardiovascular diseases

Revin, V. V., Gromova, N. V., Revina, E. S., Martynova, M. I., Seikina, A. I., Revina, N. V., Imarova, O. G., Solomadin, I. N., Tychkov, A. Y. & Zhelev, N., 2016, In : BioMed Research International. 2016, p. 1-11 11 p., 3429604.

Research output: Contribution to journalArticle

Open Access
File
Membrane Lipids
Hemoglobins
Cardiovascular Diseases
Erythrocytes
Interference Microscopy
2015
19 Citations (Scopus)
10 Downloads (Pure)

Discovery and development of Seliciclib. How systems biology approaches can lead to better drug performance

Khalil, H. S., Mitev, V., Vlaykova, T., Cavicchi, L. & Zhelev, N., 20 May 2015, In : Journal of Biotechnology. 202, p. 40-49 10 p.

Research output: Contribution to journalArticle

Open Access
File
Systems Biology
Cell growth
Pharmaceutical Preparations
Animals
Testing
2014
121 Citations (Scopus)

NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis

South, A. P., Purdie, K. J., Watt, S. A., Haldenby, S., den Breems, N., Dimon, M., Arron, S. T., Kluk, M. J., Aster, J. C., McHugh, A., Xue, D. J., Dayal, J. H. S., Robinson, K. S., Rizvi, S. M. H., Proby, C. M., Harwood, C. A. & Leigh, I. M., Oct 2014, In : Journal of Investigative Dermatology. 134, 10, p. 2630-2638 9 p.

Research output: Contribution to journalArticle

Skin
Carcinogenesis
Epithelial Cells
Mutation
Dermatology
2013

Erratum to: A high-fat-diet-induced cognitive deficit in rats that is not prevented by improving insulin sensitivity with metformin

McNeilly, A. D., Williamson, R., Balfour, D. J. K., Stewart, C. A. & Sutherland, C., 1 Jan 2013, In : Diabetologia. 56, 1, p. 230 1 p.

Research output: Contribution to journalComment/debate

18 Citations (Scopus)

Phosphorylation of Crm1 by CDK1-cyclin-B promotes Ran-dependent mitotic spindle assembly

Wu, Z., Jiang, Q., Clarke, P. R. & Zhang, C., 1 Aug 2013, In : Journal of Cell Science. 126, 15, p. 3417-3428 12 p.

Research output: Contribution to journalArticle

Cyclin B
Spindle Apparatus
Cell Nucleus Active Transport
Mitosis
Phosphorylation
2008
5 Citations (Scopus)

The isothiocyanate sulforaphane induces the phase 2 response by signaling of the Keap1-Nrf2-are pathway: Implications for dietary protection against cancer

Dinkova-Kostova, A. T., 26 Sep 2008, Dietary Modulation of Cell Signaling Pathways. Surh, Y-J., Dong, Z., Cadenas, E. & Packer, L. (eds.). 1 ed. CRC Press, p. 205-227 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Enzymes
Neoplasms
Oxidants
Animals
Antioxidants
2007
2 Citations (Scopus)

Anchoring RCC1 by the tail

Clarke, P. R., 1 May 2007, In : Nature Cell Biology. 9, 5, p. 485-487 3 p.

Research output: Contribution to journalArticle

Guanine Nucleotide Exchange Factors
Spindle Apparatus
Cell Nucleus Active Transport
Nuclear Envelope
Post Translational Protein Processing
14 Citations (Scopus)

Bis(2-hydroxybenzylidene)acetone, a potent inducer of the phase 2 response, causes apoptosis in mouse leukemia cells through a p53-independent, caspase-mediated pathway

Dinkova-Kostova, A. T., Cory, A. H., Bozak, R. E., Hicks, R. J. & Cory, J. G., 8 Jan 2007, In : Cancer Letters. 245, 1-2, p. 341-349 9 p.

Research output: Contribution to journalArticle

Caspases
Leukemia
Apoptosis
Caspase 3
Caspase 10
6 Citations (Scopus)

Chemoprotection against cancer: An idea whose time has come

Dinkova-Kostova, A. T., 1 Mar 2007, In : Alternative Therapies in Health and Medicine. 13, 2, p. S122-S127

Research output: Contribution to journalArticle

117 Citations (Scopus)

Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts

Dinkova-Kostova, A. T., Fahey, J. W., Wade, K. L., Jenkins, S. N., Shapiro, T. A., Fuchs, E. J., Kerns, M. L. & Talalay, P., 1 Apr 2007, In : Cancer Epidemiology Biomarkers and Prevention. 16, 4, p. 847-851 5 p.

Research output: Contribution to journalArticle

Open Access
Brassica
Skin
Enzymes
Safety
Heme Oxygenase-1
54 Citations (Scopus)

Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities

Liby, K., Honda, T., Williams, C. R., Risingsong, R., Royce, D. B., Suh, N., Dinkova-Kostova, A. T., Stephenson, K. K., Talalay, P., Sundararajan, C., Gribble, G. W. & Sporn, M. B., 1 Jul 2007, In : Molecular Cancer Therapeutics. 6, 7, p. 2113-2119 7 p.

Research output: Contribution to journalArticle

Open Access
Pentacyclic Triterpenes
Plant Bark
Apoptosis
Betula
betulinic acid
38 Citations (Scopus)

Phenolic Michael reaction acceptors: Combined direct and indirect antioxidant defenses against electrophiles and oxidants

Dinkova-Kostova, A. T., Cheah, J., Samouilov, A., Zweier, J. L., Bozak, R. E., Hicks, R. J. & Talalay, P., 1 May 2007, In : Medicinal Chemistry. 3, 3, p. 261-268 8 p.

Research output: Contribution to journalArticle

Oxidants
Antioxidants
Hydroxyl Radical
Thioredoxin-Disulfide Reductase
Chalcone
212 Citations (Scopus)

Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast

Cornblatt, B. S., Ye, L., Dinkova-Kostova, A. T., Erb, M., Fahey, J. W., Singh, N. K., Chen, M. S. A., Stierer, T., Garrett-Mayer, E., Argani, P., Davidson, N. E., Talalay, P., Kensler, T. W. & Visvanathan, K., 1 Jul 2007, In : Carcinogenesis. 28, 7, p. 1485-1490 6 p.

Research output: Contribution to journalArticle

Brassica
Chemoprevention
Breast
Glucosinolates
Heme Oxygenase-1
31 Citations (Scopus)

Protein kinases, from B to C

Cameron, A. J., De Rycker, M., Calleja, V., Alcor, D., Kjaer, S., Kostelecky, B., Saurin, A., Faisal, A., Laguerre, M., Hemmings, B. A., McDonald, N., Larijani, B. & Parker, P. J., 1 Nov 2007, In : Biochemical Society Transactions. 35, 5, p. 1013-1017 5 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-akt
Catalytic Domain
Phosphorylation
Protein Kinase C
Ground state
66 Citations (Scopus)

Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex

Kerns, M. L., DePianto, D., Dinkova-Kostova, A. T., Talalay, P. & Coulombe, P. A., 4 Sep 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 36, p. 14460-14465 6 p.

Research output: Contribution to journalArticle

Open Access
Epidermolysis Bullosa Simplex
Keratins
Skin
Keratinocytes
Intermediate Filaments
2006
122 Citations (Scopus)

Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress

Muqit, M. M. K., Abou-Sleiman, P. M., Saurin, A. T., Harvey, K., Gandhi, S., Deas, E., Eaton, S., Payne Smith, M. D., Venner, K., Matilla, A., Healy, D. G., Gilks, W. P., Lees, A. J., Holton, J., Revesz, T., Parker, P. J., Harvey, R. J., Wood, N. W. & Latchman, D. S., Jul 2006, In : Journal of Neurochemistry. 98, 1, p. 156-169 14 p.

Research output: Contribution to journalArticle

Parkinson Disease
Lewy Bodies
Mitochondria
Mitochondrial Proteins
Brain
26 Citations (Scopus)

Cell Biology: Ran, Mitosis and the Cancer Connection

Sanderson, H. S. & Clarke, P. R., 20 Jun 2006, In : Current Biology. 16, 12, p. R466-R468 3 p.

Research output: Contribution to journalShort survey

Open Access
Cytology
mitotic spindle apparatus
Spindle Apparatus
Monomeric GTP-Binding Proteins
guanosinetriphosphatase
162 Citations (Scopus)

Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts

Dinkova-Kostova, A. T., Jenkins, S. N., Fahey, J. W., Ye, L., Wehage, S. L., Liby, K. T., Stephenson, K. K., Wade, K. L. & Talalay, P., 28 Aug 2006, In : Cancer Letters. 240, 2, p. 243-252 10 p.

Research output: Contribution to journalArticle

Brassica
Ultraviolet Rays
Carcinogenesis
Skin
Radiation
218 Citations (Scopus)

Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: A clinical phase I study

Shapiro, T. A., Fahey, J. W., Dinkova-Kostova, A. T., Holtzclaw, W. D., Stephenson, K. K., Wade, K. L., Ye, L. & Talalay, P., 5 Oct 2006, In : Nutrition and Cancer. 55, 1, p. 53-62 10 p.

Research output: Contribution to journalArticle

Isothiocyanates
Glucosinolates
sprouts (food)
Brassica
isothiocyanates
2005
16 Citations (Scopus)

A gradient signal orchestrates the mitotic spindle

Clarke, P. R., 26 Aug 2005, In : Science. 309, 5739, p. 1334-1335 2 p.

Research output: Contribution to journalReview article

72 Citations (Scopus)

Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes

Fahey, J. W., Stephenson, K. K., Dinkova-Kostova, A. T., Egner, P. A., Kensler, T. W. & Talalay, P., 1 Jul 2005, In : Carcinogenesis. 26, 7, p. 1247-1255 9 p.

Research output: Contribution to journalArticle

Open Access
Tetrapyrroles
Chlorophyll
Carotenoids
Genes
Polyenes
30 Citations (Scopus)

Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway

Clarke, C. A. L., Bennett, L. N. & Clarke, P. R., 21 Oct 2005, In : Journal of Biological Chemistry. 280, 42, p. 35337-35345 9 p.

Research output: Contribution to journalArticle

Caspase 7
DNA Damage
Apoptosis
Phosphorylation
DNA
70 Citations (Scopus)

DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system

Clarke, C. A. L. & Clarke, P. R., 1 Jun 2005, In : Biochemical Journal. 388, 2, p. 705-712 8 p.

Research output: Contribution to journalArticle

Phosphorylation
Cell-Free System
Cells
Automatic teller machines
DNA
151 Citations (Scopus)

Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein

Dinkova-Kostova, A. T., Holtzclaw, W. D. & Wakabayashi, N., 10 May 2005, In : Biochemistry. 44, 18, p. 6889-6899 11 p.

Research output: Contribution to journalArticle

Metalloproteins
Oxidants
Zinc
Sensors
Sulfhydryl Compounds
79 Citations (Scopus)

Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c

Martin, M. C., Allan, L. A., Lickrish, M., Sampson, C., Morrice, N. & Clarke, P. R., 15 Apr 2005, In : Journal of Biological Chemistry. 280, 15, p. 15449-15455 7 p.

Research output: Contribution to journalArticle

Cytochromes c1
Caspase 9
Cyclic AMP-Dependent Protein Kinases
Cytochromes c
Chemical activation
7 Citations (Scopus)

The Crm de la crème of mitosis

Clarke, P. R., 1 Jun 2005, In : Nature Cell Biology. 7, 6, p. 551-552 2 p.

Research output: Contribution to journalArticle

Cell Nucleus Active Transport
Mitosis
Kinetochores
Monomeric GTP-Binding Proteins
Guanosine Triphosphate
272 Citations (Scopus)

The role of Keap1 in cellular protective responses

Dinkova-Kostova, A. T., Holtzclaw, W. D. & Kensler, T. W., 1 Dec 2005, In : Chemical Research in Toxicology. 18, 12, p. 1779-1791 13 p.

Research output: Contribution to journalReview article

2004
109 Citations (Scopus)

Chemical Structures of Inducers of Nicotinamide Quinone Oxidoreductase 1 (NQO1)

Dinkova-Kostova, A. T., Fahey, J. W. & Talalay, P., 2004, In : Methods in Enzymology. 382, p. 423-448 26 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)
Oxidative Stress
Cysteine
Sulfhydryl Compounds
Oxidants
Genes
28 Citations (Scopus)

Redox ranking of inducers of a cancer-protective enzyme via the energy of their highest occupied molecular orbital

Zoete, V., Rougée, M., Dinkova-Kostova, A. T., Talalay, P. & Bensasson, R. V., 1 Jun 2004, In : Free Radical Biology and Medicine. 36, 11, p. 1418-1423 6 p.

Research output: Contribution to journalArticle

Molecular orbitals
Oxidation-Reduction
Electrons
Enzymes
NAD(P)H Dehydrogenase (Quinone)