Cellular Medicine

Research Output 1984 2020

2014
128 Citations (Scopus)

NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis

South, A. P., Purdie, K. J., Watt, S. A., Haldenby, S., den Breems, N., Dimon, M., Arron, S. T., Kluk, M. J., Aster, J. C., McHugh, A., Xue, D. J., Dayal, J. H. S., Robinson, K. S., Rizvi, S. M. H., Proby, C. M., Harwood, C. A. & Leigh, I. M., Oct 2014, In : Journal of Investigative Dermatology. 134, 10, p. 2630-2638 9 p.

Research output: Contribution to journalArticle

Skin
Carcinogenesis
Epithelial Cells
Mutation
Dermatology
2015
20 Citations (Scopus)
24 Downloads (Pure)

Discovery and development of Seliciclib. How systems biology approaches can lead to better drug performance

Khalil, H. S., Mitev, V., Vlaykova, T., Cavicchi, L. & Zhelev, N., 20 May 2015, In : Journal of Biotechnology. 202, p. 40-49 10 p.

Research output: Contribution to journalArticle

Open Access
File
Systems Biology
Cell growth
Pharmaceutical Preparations
Animals
Testing
2016
38 Citations (Scopus)
90 Downloads (Pure)

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

Cammareri, P., Rose, A., Vincent, D. F., Wang, J., Nagano, A., Libertini, S., Ridgway, R. A., Athineos, D., Coates, P. J. ., McHugh, A., Pourreyron, C., Dayal, J., Larsson, J., Weidlich, S., Spender, L., Sapkota, G., Purdie, K. J., Proby, C., Harwood, C. A., Leigh, I. & 9 others, Clevers, H., Barker, N., Karlsson, S., Pritchard, C., Marais, R., Chelala, C., South, A., Sansom, O. J. & Inman, G., 25 Aug 2016, In : Nature Communications. 7, p. 1-7 7 p., 12493.

Research output: Contribution to journalArticle

Open Access
File
stem cells
Stem cells
deactivation
Squamous Cell Carcinoma
Stem Cells
20 Citations (Scopus)
85 Downloads (Pure)

QTL meta-analysis of root traits in Brassica napus under contrasting phosphorus supply in two growth systems

Zhang, Y., Thomas, C. L., Xiang, J., Long, Y., Wang, X., Zou, J., Luo, Z., Ding, G., Cai, H., Graham, N. S., Hammond, J. P., King, G. J., White, P. J., Xu, F., Broadley, M. R., Shi, L. & Meng, J., 14 Sep 2016, In : Scientific Reports. 6, p. 1-12 12 p., 33113.

Research output: Contribution to journalArticle

Open Access
File
Brassica napus
Quantitative Trait Loci
Phosphorus
Meta-Analysis
Growth
8 Citations (Scopus)
23 Downloads (Pure)

Role of membrane lipids in the regulation of erythrocytic oxygen-transport function in cardiovascular diseases

Revin, V. V., Gromova, N. V., Revina, E. S., Martynova, M. I., Seikina, A. I., Revina, N. V., Imarova, O. G., Solomadin, I. N., Tychkov, A. Y. & Zhelev, N., 2016, In : BioMed Research International. 2016, p. 1-11 11 p., 3429604.

Research output: Contribution to journalArticle

Open Access
File
Membrane Lipids
Hemoglobins
Cardiovascular Diseases
Erythrocytes
Interference Microscopy
2017
5 Citations (Scopus)
79 Downloads (Pure)

Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE-/- mouse model of atherosclerosis with alterations in IL10/AMPKa pathway

Thompson, D., Morrice, N., Grant, L., Le Sommer, S., Ziegler, K., Whitfield, P., Mody, N., Wilson, H. & Delibegovic, M., Jun 2017, In : Molecular Metabolism. 6, 8, p. 845-853

Research output: Contribution to journalArticle

Open Access
File
Non-Receptor Type 1 Protein Tyrosine Phosphatase
Apolipoproteins E
Atherosclerotic Plaques
Interleukin-10
Atherosclerosis
7 Citations (Scopus)
24 Downloads (Pure)

Pharamcological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in LDLR-/- mouse model of atherosclerosis

Thompson, D., Morrice, N., Grant, L., Lees, E. K., Mody, N., Wilson, H. & Delibegovic, M., 29 Sep 2017, In : Clinical Science. 131, 20, p. 2489-2501

Research output: Contribution to journalArticle

Open Access
File
Non-Receptor Type 1 Protein Tyrosine Phosphatase
Atherosclerotic Plaques
Atherosclerosis
Insulin Receptor
Cardiovascular Diseases
2 Citations (Scopus)
92 Downloads (Pure)

Physical and Chemical Processes and the Morphofunctional Characteristics of Human Erythrocytes in Hyperglycaemia

Revin, V. V., Klenova, N. A., Gromova, N. V., Grunyushkin, I. P., Solomadin, I. N., Tychkov, A. Y., Pestryakova, A. A., Sadykhova, A. V., Revina, E. S., Prosnikova, K. V., Bourdon, J-C. & Zhelev, N., 30 Aug 2017, In : Frontiers in Physiology. 8, 606.

Research output: Contribution to journalArticle

Open Access
File
Chemical Phenomena
Physical Phenomena
Hyperglycemia
Hemoglobins
Erythrocytes
23 Downloads (Pure)

Some problems and errors in cytogenetic biodosimetry

Mosse, I., Kilchevsky, A., Nikolova, N. & Zhelev, N., 4 May 2017, In : Biotechnology and Biotechnological Equipment. 31, 3, p. 460-468 9 p.

Research output: Contribution to journalReview article

Open Access
File
Radiation Tolerance
Cytogenetics
Alleles
Binomial Distribution
Interspersed Repetitive Sequences
2018
7 Citations (Scopus)
94 Downloads (Pure)

A comparative pharmacokinetic study of PARP inhibitors demonstrates favorable properties for niraparib efficacy in preclinical tumor models

Sun, K., Mikule, K., Wang, Z., Poon, G., Vaidyanathan, A., Smith, G., Zhang, Z. Y., Hanke, J., Ramaswamy, S. & Wang, J., 14 Dec 2018, In : Oncotarget. 9, 98, p. 37080-37096 17 p.

Research output: Contribution to journalArticle

Open Access
File
Pharmacokinetics
Neoplasms
Cell Membrane Permeability
niraparib
Poly(ADP-ribose) Polymerase Inhibitors
16 Citations (Scopus)
103 Downloads (Pure)

A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia

Baardman, J., Verberk, S. G. S., Prange, K. H. M., van Weeghel, M., van der Velden, S., Ryan, D. G., Wüst, R. C. I., Neele, A. E., Speijer, D., Denis, S. W., Witte, M. E., Houtkooper, R. H., O'neill, L. A., Knatko, E. V., Dinkova-Kostova, A. T., Lutgens, E., de Winther, M. P. J. & Van den Bossche, J., 20 Nov 2018, In : Cell Reports. 25, 8, p. 2044-2052.e5 15 p.

Research output: Contribution to journalArticle

Open Access
File
Pentoses
Pentose Phosphate Pathway
Macrophages
Hypercholesterolemia
Metabolism
6 Citations (Scopus)
123 Downloads (Pure)

Atypical APC/C-dependent degradation of Mcl-1 provides an apoptotic timer during mitotic arrest

Allan, L. A., Skowyra, A., Rogers, K. I., Zeller, D. & Clarke, P. R., 3 Sep 2018, In : The EMBO Journal. 37, 17, p. 1-15 15 p., e96831.

Research output: Contribution to journalArticle

Open Access
File
Anaphase-Promoting Complex-Cyclosome
Mitosis
Degradation
Ubiquitin-Protein Ligases
Isoleucine
64 Downloads (Pure)

Correction: The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth

Hanson, K., Robinson, S. D., Al-Yousuf, K., Hendry, A. E., Sexton, D. W., Sherwood, V. & Wheeler, G. N., 27 Nov 2018, In : Oncotarget. 9, 93, p. 36645 1 p.

Research output: Contribution to journalArticle

Open Access
File
leflunomide
Antirheumatic Agents
Mitogen-Activated Protein Kinase Kinases
Melanoma
Growth

Cutaneous immunohistochemical staining pattern of p53β isoforms

Ko, C. J., Myung, P., Leffell, D. J. & Bourdon, J-C., Dec 2018, In : Journal of Clinical Pathology. 71, 12, p. 1120-1122 3 p.

Research output: Contribution to journalArticle

Protein Isoforms
Staining and Labeling
Skin
Cytoplasm
Mutation
6 Citations (Scopus)
75 Downloads (Pure)

Deficiency in Protein Tyrosine Phosphatase PTP1B shortens lifespan and leads to development of acute leukemia

Le Sommer, S., Morrice, N., Pesaresi, M., Thompson, D., Vickers, M. A., Murray, G. I., Mody, N., Neel, B. G., Bence, K. K., Wilson, H. M. & Delibegović, M., Jan 2018, In : Cancer Research. 78, 1, p. 75-87 14 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Tyrosine Phosphatases
Leukemia
Myeloid Cells
Acute Myeloid Leukemia
Liver
7 Citations (Scopus)
112 Downloads (Pure)

DHX9 Helicase promotes R-loop formation in cells with impaired RNA splicing

Chakraborty, P., Huang, J. & Hiom, K., 19 Oct 2018, In : Nature Communications. 9, 9, p. 1-14 14 p., 4346.

Research output: Contribution to journalArticle

Open Access
File
RNA Splicing
splicing
RNA
cells
Chromosome Fragility
2 Citations (Scopus)
37 Downloads (Pure)

Differential expression of secreted factors SOSTDC1 and ADAMTS8 cause pro-fibrotic changes in linear morphoea fibroblasts

Badshah, I. I., Brown, S., Weibel, L., Rose, A., Way, B., Sebire, N., Inman, G., Harper, J., Kinsler, V. & O'Shaughnessy, R., 26 Oct 2018, In : British Journal of Dermatology.

Research output: Contribution to journalArticle

Open Access
File
Localized Scleroderma
Fibroblasts
Myofibroblasts
Transforming Growth Factors
Therapeutics
76 Downloads (Pure)

Druggable Nucleolin Identifies Breast Tumours Associated with Poor Prognosis That Exhibit Different Biological Processes

Nguyen Van Long, F., Lardy-Cleaud, A., Bray, S., Chabaud, S., Dubois, T., Diot, A., Thompson, A. M., Bourdon, J-C., Perol, D., Bouvet, P., Diaz, J-J. & Marcel, V., 22 Oct 2018, In : Cancers. 10, 10, p. 1-11 11 p., 390.

Research output: Contribution to journalArticle

Open Access
File
Biological Phenomena
Breast Neoplasms
Triple Negative Breast Neoplasms
Messenger RNA
Neoplasms
1 Citation (Scopus)

Effect of Dinitrosyl Iron Complexes (NO Donors) on the Metabolic Processes in Human Fibroblasts

Gizatullin, A. R., Akentieva, N. P., Sanina, N. A., Shmatko, N. Y., Goryachev, N. S., Shkondina, N. I., Prichodchenko, T. R., Zhelev, N. & Aldoshin, S. M., Nov 2018, In : Doklady Biochemistry and Biophysics. 483, 1, p. 337-340 4 p.

Research output: Contribution to journalArticle

Fibroblasts
Cell Survival
Iron Compounds
Mitochondrial Membrane Potential
Sulfur
22 Downloads (Pure)

Effect of liquid nitrogen pre-treatment on various types of wool waste fibres for biogas production

Kuzmanova, E., Zhelev, N. & Akunna, J. C., May 2018, In : Heliyon. 4, 5, p. 1-11 11 p., e00619.

Research output: Contribution to journalArticle

Open Access
File
wool
biogas
liquid
nitrogen
methane

Erratum to: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions (Nature, (2015), 528, 7583, (517-522), 10.1038/nature16193)

Huang, W., Thomas, B., Flynn, R. A., Gavzy, S. J., Wu, L., Kim, S. V., Hall, J. A., Miraldi, E. R., Ng, C. P., Rigo, F., Meadows, S., Montoya, N. R., Herrera, N. G., Domingos, A. I., Rastinejad, F., Myers, R. M., Fuller-Pace, F. V., Bonneau, R., Chang, H. Y., Acuto, O. & 1 others, Littman, D. R., 4 Oct 2018, In : Nature. 562, 7725, 1 p.

Research output: Contribution to journalComment/debate

Long Noncoding RNA
Th17 Cells
History
27 Citations (Scopus)
115 Downloads (Pure)
Open Access
File
NF-E2-Related Factor 2
Fructose
Liver Cirrhosis
Fats
Endoplasmic Reticulum Stress
1 Citation (Scopus)
25 Downloads (Pure)

Individual capacity for repair of DNA damage and potential uses of stem cell lines for clinical applications: a matter of (genomic) integrity

Petkova, R., Zhelev, N., Pankov, R. & Chakarov, S., 2018, In : Biotechnology and Biotechnological Equipment. 32, 6, p. 1352-1358 7 p.

Research output: Contribution to journalReview article

Open Access
File
DNA Damage
Stem Cells
Cell Line
Pluripotent Stem Cells
Safety
2 Citations (Scopus)

In vitro screening of cell bioenergetics to assess mitochondrial dysfunction in drug development

Tilmant, K., Gerets, H., De Ron, P., Hanon, E., Bento-Pereira, C. & Atienzar, F. A., 1 Oct 2018, In : Toxicology in Vitro. 52, p. 374-383 10 p.

Research output: Contribution to journalArticle

Chemical and Drug Induced Liver Injury
Energy Metabolism
Screening
Poisons
Pharmaceutical Preparations
13 Citations (Scopus)
88 Downloads (Pure)

Kinase and Phosphatase Cross-Talk at the Kinetochore

Saurin, A. T., 19 Jun 2018, In : Frontiers in Cell and Developmental Biology. 6, p. 1-23 23 p., 62.

Research output: Contribution to journalReview article

Open Access
File
Kinetochores
Phosphoric Monoester Hydrolases
Phosphotransferases
Enzymes
M Phase Cell Cycle Checkpoints
10 Citations (Scopus)
96 Downloads (Pure)

Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease

Arnoux, I., Willam, M., Griesche, N., Krummeich, J., Watari, H., Offermann, N., Weber, S., Narayan Dey, P., Chen, C., Monteiro, O., Buettner, S., Meyer, K., Bano, D., Radyushkin, K., Langston, R., Lambert, J. J., Wanker, E., Methner, A., Krauss, S., Schweiger, S. & 1 others, Stroh, A., 4 Sep 2018, In : eLife. 7, p. 1-32 32 p., e38744.

Research output: Contribution to journalArticle

Open Access
File
Metformin
Huntington Disease
Animal Behavior
Aberrations
Visual Cortex
5 Citations (Scopus)
108 Downloads (Pure)

Phenethyl isothiocyanate, a dual activator of transcription factors NRF2 and HSF1

Dayalan Naidu, S., Suzuki, T., Yamamoto, M., Fahey, J. W. & Dinkova-Kostova, A., 1 Sep 2018, In : Molecular Nutrition & Food Research. 62, 18, p. e1700908 9 p., 1700908.

Research output: Contribution to journalReview article

Open Access
File
isothiocyanates
heat stress
transcription factors
Vegetables
Glucosinolates
10 Citations (Scopus)
103 Downloads (Pure)

Prediction of Pathological Complete Response to Neoadjuvant Chemotherapy for Primary Breast Cancer Comparing Interim Ultrasound, Shear Wave Elastography and MRI

Evans, A., Whelehan, P., Thompson, A., Purdie, C., Jordan, L., Macaskill, J., Waugh, S., Fuller-Pace, F., Brauer, K. & Vinnicombe, S., Aug 2018, In : European Journal of Ultrasound. 39, 04, p. 422-431 10 p.

Research output: Contribution to journalArticle

Open Access
File
Elasticity Imaging Techniques
Magnetic Resonance Imaging
Breast Neoplasms
Drug Therapy
Sensitivity and Specificity
3 Citations (Scopus)
77 Downloads (Pure)

Pre-operative stromal stiffness measured by shear wave elastography is independently associated with breast cancer specific survival

Evans, A., Sim, Y. T., Pourreyron, C., Thompson, A., Jordan, L., Fleming, D., Purdie, C., Macaskill, J., Vinnicombe, S. & Pharoah, P., 1 Jun 2018, In : Breast Cancer Research and Treatment. 171, 2, p. 383-389 7 p.

Research output: Contribution to journalArticle

Open Access
File
Elasticity Imaging Techniques
Breast Neoplasms
Survival
Biopsy
Neoplasms
1 Citation (Scopus)
71 Downloads (Pure)

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

Ladds, M. J. G. W., Van Leeuwen, I. M. M., Drummond, C. J., Chu, S., Healy, A. R., Popova, G., Pastor Fernández, A., Mollick, T., Darekar, S., Sedimbi, S. K., Nekulova, M., Sachweh, M. C. C., Campbell, J., Higgins, M., Tuck, C., Popa, M., Safont, M. M., Gelebart, P., Fandalyuk, Z., Thompson, A. M. & 26 others, Svensson, R., Gustavsson, A. L., Johansson, L., Färnegårdh, K., Yngve, U., Saleh, A., Haraldsson, M., D'Hollander, A. C. A., Franco, M., Zhao, Y., Håkansson, M., Walse, B., Larsson, K., Peat, E. M., Pelechano, V., Lunec, J., Vojtesek, B., Carmena, M., Earnshaw, W. C., McCarthy, A. R., Westwood, N. J., Arsenian-Henriksson, M., Lane, D. P., Bhatia, R., McCormack, E. & Laín, S., 22 May 2018, In : Nature Communications. 9, 1, p. 2071 2071.

Research output: Contribution to journalArticle

Open Access
File
document markup languages
inhibitors
Publications
Tumors
tumors
4 Citations (Scopus)
32 Downloads (Pure)

The collagen prolyl hydroxylases are bifunctional growth regulators in melanoma

Atkinson, A., Renziehausen, A., Wang, H., Nigro, C. L., Lattanzio, L., Merlano, M., Rao, B., Weir, L., Evans, A., Matin, R., Harwood, C., Szlosarek, P., Pickering, J. G., Fleming, C., Sim, V. R., Li, S., Vasta, J. T., Raines, R. T., Boniol, M., Thompson, A. & 3 others, Proby, C., Crook, T. & Syed, N., 16 Nov 2018, In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

Open Access
File
Prolyl Hydroxylases
Melanoma
Collagen
Growth
Tumors
108 Downloads (Pure)

The effect of experimental hyperoxia on erythrocytes’ oxygen-transport function

Revin, V. V., Gromova, N. V., Revina, E. S., Grunyushkin, I. P., Tychkov, A. Y., Samonova, A. Y., Kukina, A. N., Moskovkin, A. A., Bourdon, J. C. & Zhelev, N., 2018, In : Biotechnology and Biotechnological Equipment. 32, 5, p. 1236-1250 15 p.

Research output: Contribution to journalArticle

Open Access
File
Hyperoxia
Erythrocytes
Oxygen
Erythrocyte Membrane
Ions
24 Citations (Scopus)
105 Downloads (Pure)

The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature

Inman, G. J., Wang, J., Nagano, A., Alexandrov, L. B., Purdie, K. J., Taylor, R. G., Sherwood, V., Thomson, J., Hogan, S., Spender, L. C., South, A. P., Stratton, M., Chelala, C., Harwood, C. A., Proby, C. M. & Leigh, I. M., 10 Sep 2018, In : Nature Communications. 9, 1, p. 1-14 14 p., 3667.

Research output: Contribution to journalArticle

Open Access
File
Azathioprine
Tumors
tumors
signatures
Skin
4 Citations (Scopus)
4 Downloads (Pure)

The role of APETALA1 in petal number robustness

Monniaux, M., Pieper, B., McKim, S. M., Routier-Kierzkowska, A. L., Kierzkowski, D., Smith, R. S. & Hay, A., 18 Oct 2018, In : eLife. 7, p. 1-22 22 p., e39399.

Research output: Contribution to journalArticle

Open Access
File
Nucleic Acid Regulatory Sequences
Arabidopsis
Cardamine
Quantitative Trait Loci
3 Citations (Scopus)
94 Downloads (Pure)

The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions

Purdie, K. J., Proby, C. M., Rizvi, H., Griffin, H., Doorbar, J., Sommerlad, M., Feltkamp, M. C., Van der Meijden, E., Inman, G. J., South, A. P., Leigh, I. M. & Harwood, C. A., 14 Aug 2018, In : Frontiers in Microbiology. 9, 16 p., 1806.

Research output: Contribution to journalArticle

Open Access
File
Polyomavirus
Squamous Cell Carcinoma
Skin
Mutation
Warts
34 Citations (Scopus)
180 Downloads (Pure)

The role of Nrf2 signaling in counteracting neurodegenerative diseases

Dinkova-Kostova, A. T., Kostov, R. V. & Kazantsev, A. G., 1 Oct 2018, In : FEBS Journal. 285, 19, p. 3576-3590 15 p.

Research output: Contribution to journalReview article

Open Access
File
Neurodegenerative diseases
Neurodegenerative Diseases
Antioxidants
Detoxification
NF-E2 Transcription Factor
90 Downloads (Pure)

Timed degradation of Mcl-1 controls mitotic cell death

Clarke, P. R., Allan, L. A. & Skowyra, A., 2 Nov 2018, In : Molecular and Cellular Oncology. 5, 6, p. 1-4 4 p., e1516450.

Research output: Contribution to journalArticle

Open Access
File
Anaphase-Promoting Complex-Cyclosome
Proteasome Endopeptidase Complex
Ubiquitin
Mitosis
Proteolysis
5 Citations (Scopus)
58 Downloads (Pure)
Open Access
File
Cullin Proteins
NF-E2-Related Factor 2
Zinc
Transcription Factors
Switches
2019
3 Citations (Scopus)
74 Downloads (Pure)

Acute effects of electronic and tobacco cigarettes on vascular and respiratory function in healthy volunteers: a cross-over study

Kerr, D. M. I., Brooksbank, K. J. M., Taylor, R. G., Pinel, K., Rios, F. J., Touyz, R. M. & Delles, C., Jan 2019, In : Journal of Hypertension. 37, 1, p. 154-166 13 p.

Research output: Contribution to journalArticle

Open Access
File
Cross-Over Studies
Tobacco
Blood Vessels
Healthy Volunteers
Smoking
30 Downloads (Pure)

Are baseline ultrasound and mammographic features associated with rates of pathological completes response in patients receiving neoadjuvant chemotherapy for breast cancer?

Savaridas, S. L., Sim, Y. T., Vinnicombe, S. J., Purdie, C. A., Thompson, A. M. & Evans, A., 21 Oct 2019, In : Cancer Imaging. 19, 1, p. 1-7 7 p., 67.

Research output: Contribution to journalArticle

Open Access
File
Breast Neoplasms
Drug Therapy
Calcinosis
Neoplasms
Biopsy
1 Citation (Scopus)

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences

Nik-Zainal, S., Davies, H., Staaf, J., Ramakrishna, M., Glodzik, D., Zou, X., Martincorena, I., Alexandrov, L. B., Martin, S., Wedge, D. C., Van Loo, P., Ju, Y. S., Smid, M., Brinkman, A. B., Morganella, S., Aure, M. R., Lingjærde, O. C., Langerød, A., Ringnér, M., Ahn, S-M. & 68 others, Boyault, S., Brock, J. E., Broeks, A., Butler, A., Desmedt, C., Dirix, L., Dronov, S., Fatima, A., Foekens, J. A., Gerstung, M., Hooijer, G. K. J., Jang, S. J., Jones, D. R., Kim, H-Y., King, T. A., Krishnamurthy, S., Lee, H. J., Lee, J-Y., Li, Y., McLaren, S., Menzies, A., Mustonen, V., O'Meara, S., Pauporté, I., Pivot, X., Purdie, C. A., Raine, K., Ramakrishnan, K., Rodríguez-González, F. G., Romieu, G., Sieuwerts, A. M., Simpson, P. T., Shepherd, R., Stebbings, L., Stefansson, O. A., Teague, J., Tommasi, S., Treilleux, I., Van den Eynden, G. G., Vermeulen, P., Vincent-Salomon, A., Yates, L., Caldas, C., Van't Veer, L., Tutt, A., Knappskog, S., Tan, B. K. T., Jonkers, J., Borg, Å., Ueno, N. T., Sotiriou, C., Viari, A., Futreal, P. A., Campbell, P. J., Span, P. N., Van Laere, S., Lakhani, S. R., Eyfjord, J. E., Thompson, A. M., Birney, E., Stunnenberg, H. G., van de Vijver, M. J., Martens, J. W. M., Børresen-Dale, A-L., Richardson, A. L., Kong, G., Thomas, G. & Stratton, M. R., 7 Feb 2019, In : Nature. 566, 7742, p. E1 1 p.

Research output: Contribution to journalArticle

Genome
Breast Neoplasms
Mutation
1 Citation (Scopus)

Azathioprine: friend or foe?

Leigh, I. M., Proby, C. M., Inman, G. J. & Harwood, C. A., May 2019, In : British Journal of Dermatology. 180, 5, p. 961-963 3 p.

Research output: Contribution to journalEditorial

4 Downloads (Pure)

Breast MRI and tumour biology predict axillary lymph node response to neoadjuvant chemotherapy for breast cancer

Al-hattali, S., Vinnicombe, S. J., Gowdh, N. M., Evans, A., Armstrong, S., Adamson, D., Purdie, C. A. & Macaskill, E. J., 26 Dec 2019, In : Cancer Imaging. 19, 1, p. 1-9 9 p., 91.

Research output: Contribution to journalArticle

Open Access
File
Breast
Lymph Nodes
Magnetic Resonance Imaging
Breast Neoplasms
Drug Therapy
72 Downloads (Pure)

Broccoli or Sulforaphane: Is It the Source or Dose That Matters?

Yagishita, Y., Fahey, J. W., Dinkova-Kostova, A. T. & Kensler, T. W., 6 Oct 2019, In : Molecules and Cells. 24, 19, p. 1-38 38 p., 3593.

Research output: Contribution to journalReview article

Open Access
File
Brassica
Pharmacodynamics
beverages
public health
bioavailability
12 Downloads (Pure)

Cytoprotective Effects of Dinitrosyl Iron Complexes on Viability of Human Fibroblasts and Cardiomyocytes

Akentieva, N. P., Sanina, N. A., Gizatullin, A. R., Shkondina, N. I., Prikhodchenko, T. R., Shram, S. I., Zhelev, N. & Aldoshin, S. M., 11 Nov 2019, In : Frontiers in Pharmacology. 10, p. 1-10 21 p., 1277.

Research output: Contribution to journalArticle

Open Access
File
Cardiac Myocytes
Fibroblasts
Doxorubicin
Mitochondria
Nitric Oxide
3 Citations (Scopus)
65 Downloads (Pure)

DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia

Legrand, J. M. D., Chan, A-L., La, H. M., Rossello, F. J., Änkö, M-L., Fuller-Pace, F. V. & Hobbs, R. M., 23 May 2019, In : Nature Communications. 10, 1, p. 1-21 21 p., 2278.

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spermatogenesis
Spermatogonia
maintenance
Spermatogenesis
Genes
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Delay in development and behavioural abnormalities in the absence of p53 in zebrafish

Elabd, S., Jabeen, N. A., Gerber, V., Peravali, R., Bourdon, J-C., Kancherla, S., Vallone, D. & Blattner, C., 19 Jul 2019, In : PLoS ONE. 14, 7, 18 p., e0220069.

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Clustered Regularly Interspaced Short Palindromic Repeats
Cell proliferation
Zebrafish
Stem cells
Danio rerio
2 Citations (Scopus)
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Division of labour between PP2A-B56 isoforms at the centromere and kinetochore

Vallardi, G., Allan, L., Crozier, L. & Saurin, A. T., 4 Mar 2019, In : eLife. 8, p. 1-25 25 p., e42619.

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Kinetochores
Centromere
Protein Isoforms
Personnel
M Phase Cell Cycle Checkpoints
4 Citations (Scopus)
130 Downloads (Pure)

Dual-specificity MAP kinase phosphatases in health and disease

Seternes, O-M., Kidger, A. M. & Keyse, S., 1 Jan 2019, In : BBA - Molecular Cell Research. 1866, 1, p. 124-143 20 p.

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Phosphoric Monoester Hydrolases
Phosphotransferases
Health
MAP Kinase Signaling System
Genetic Models
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Editorial: Metformin: Beyond Diabetes

Bost, F., Rena, G. & Viollet, B., 6 Dec 2019, In : Frontiers in endocrinology. 10, p. 1-3 3 p., 851.

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Open Access
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