Cellular Medicine

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2020

Activation of transcription factor Nrf2 to counteract mitochondrial dysfunction in Parkinson’s disease

Bento-Pereira, C. & Dinkova-Kostova, A., 18 Jul 2020, In : Medicinal Research Reviews. 18 p.

Research output: Contribution to journalReview article

Open Access
File
8 Downloads (Pure)

Can activation of NRF2 be a strategy against COVID-19?

Cuadrado, A., Pajares, M., Benito, C., Jiménez-Villegas, J., Escoll, M., Fernández-Ginés, R., Garcia Yagüe, A. J., Lastra, D., Manda, G., Rojo, A. I. & Dinkova-Kostova, A. T., 14 Jul 2020, In : Trends in Pharmacological Sciences. 13 p.

Research output: Contribution to journalReview article

Open Access

Multifaceted transforming growth factor-beta (TGFβ) signalling in glioblastoma

Birch, J. L., Coull, B. J., Spender, L. C., Watt, C., Willison, A., Syed, N., Chalmers, A. J., Hossain-Ibrahim, M. K. & Inman, G. J., Aug 2020, In : Cellular Signalling. 72, p. 1-12 12 p., 109638.

Research output: Contribution to journalReview article

1 Citation (Scopus)

New insight into the biology of R-loops

Chakraborty, P., May 2020, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 821, p. 1-8 8 p., 111711.

Research output: Contribution to journalReview article

Obesity and NRF2-mediated cytoprotection: Where is the missing link?

Vasileva, L. V., Savova, M. S., Amirova, K. M., Dinkova-Kostova, A. & Georgiev, M. I., Jun 2020, In : Pharmacological Research. 156, p. 1-9 9 p., 104760.

Research output: Contribution to journalReview article

Open Access
File
5 Citations (Scopus)
58 Downloads (Pure)

Oxidative Stress in Cancer

Hayes, J., Dinkova-Kostova, A. & Tew, K. D., 10 Aug 2020, In : Cancer Cell. 38, 31 p.

Research output: Contribution to journalReview article

2019

Broccoli or Sulforaphane: Is It the Source or Dose That Matters?

Yagishita, Y., Fahey, J. W., Dinkova-Kostova, A. T. & Kensler, T. W., Oct 2019, In : Molecules and Cells. 24, 19, p. 1-38 38 p., 3593.

Research output: Contribution to journalReview article

Open Access
File
14 Citations (Scopus)
203 Downloads (Pure)

The Emerging Landscape of p53 Isoforms in Physiology, Cancer and Degenerative Diseases

Anbarasan, T. & Bourdon, J-C., 11 Dec 2019, In : International Journal of Molecular Sciences. 20, 24, p. 1-20 20 p., 6257.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
64 Downloads (Pure)

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

Cuadrado, A., Rojo, A. I., Wells, G., Hayes, J., Cousin, S. P., Rumsey, W. L., Attucks, O. C., Franklin, S., Levonen, A-L., Kensler, T. W. & Dinkova-Kostova, A., Apr 2019, In : Nature Reviews Drug Discovery. 18, 4, p. 295-317 23 p.

Research output: Contribution to journalReview article

Open Access
File
134 Citations (Scopus)
208 Downloads (Pure)

What is the potential of p53 isoforms as a predictive biomarker in the treatment of cancer?

Hayman, L., Chaudhry, W. R., Revin, V. V., Zhelev, N. & Bourdon, J-C., Feb 2019, In : Expert Review of Molecular Diagnostics. 19, 2, p. 149-159 11 p.

Research output: Contribution to journalReview article

Open Access
File
4 Citations (Scopus)
86 Downloads (Pure)
2018

Individual capacity for repair of DNA damage and potential uses of stem cell lines for clinical applications: a matter of (genomic) integrity

Petkova, R., Zhelev, N., Pankov, R. & Chakarov, S., 2 Nov 2018, In : Biotechnology and Biotechnological Equipment. 32, 6, p. 1352-1358 7 p.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
63 Downloads (Pure)

Kinase and Phosphatase Cross-Talk at the Kinetochore

Saurin, A. T., 19 Jun 2018, In : Frontiers in Cell and Developmental Biology. 6, p. 1-23 23 p., 62.

Research output: Contribution to journalReview article

Open Access
File
21 Citations (Scopus)
135 Downloads (Pure)

Phenethyl isothiocyanate, a dual activator of transcription factors NRF2 and HSF1

Dayalan Naidu, S., Suzuki, T., Yamamoto, M., Fahey, J. W. & Dinkova-Kostova, A., 1 Sep 2018, In : Molecular Nutrition & Food Research. 62, 18, p. e1700908 9 p., 1700908.

Research output: Contribution to journalReview article

Open Access
File
9 Citations (Scopus)
155 Downloads (Pure)

The role of Nrf2 signaling in counteracting neurodegenerative diseases

Dinkova-Kostova, A. T., Kostov, R. V. & Kazantsev, A. G., 1 Oct 2018, In : FEBS Journal. 285, 19, p. 3576-3590 15 p.

Research output: Contribution to journalReview article

Open Access
File
54 Citations (Scopus)
235 Downloads (Pure)
2017

Some problems and errors in cytogenetic biodosimetry

Mosse, I., Kilchevsky, A., Nikolova, N. & Zhelev, N., 4 May 2017, In : Biotechnology and Biotechnological Equipment. 31, 3, p. 460-468 9 p.

Research output: Contribution to journalReview article

Open Access
File
62 Downloads (Pure)
2012

Differential genetic advantages in youth and in aging, or how to die healthy

Khalil, H. S., Petkova, R. & Zhelev, N., 1 Feb 2012, In : Biotechnology and Biotechnological Equipment. 26, 1, p. 2703-2711 9 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)
2011

Nothing in excess - lessons learned from the expression of high-mobility group proteins type A in non-cancer and cancer cells

Petkova, R., Tummala, H. & Zhelev, N., 1 Nov 2011, In : Biotechnology and Biotechnological Equipment. 25, 4, p. 2572-2575 4 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Repair, Abort, Ignore? Strategies for dealing with UV damage

Tummala, H., Khalil, H. S. & Zhelev, N., 27 Sep 2011, In : Biotechnology and Biotechnological Equipment. 25, 3, p. 2443-2446 4 p.

Research output: Contribution to journalReview article

Open Access
4 Citations (Scopus)
2006

The role of modelling in identifying drug targets for diseases of the cell cycle

Clyde, R. G., Bown, J. L., Hupp, T. R., Zhelev, N. & Crawford, J. W., Oct 2006, In : Journal of the Royal Society Interface. 3, 10, p. 617-627 11 p.

Research output: Contribution to journalReview article

19 Citations (Scopus)
2005

A gradient signal orchestrates the mitotic spindle

Clarke, P. R., 26 Aug 2005, In : Science. 309, 5739, p. 1334-1335 2 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)

The role of Keap1 in cellular protective responses

Dinkova-Kostova, A. T., Holtzclaw, W. D. & Kensler, T. W., 1 Dec 2005, In : Chemical Research in Toxicology. 18, 12, p. 1779-1791 13 p.

Research output: Contribution to journalReview article

287 Citations (Scopus)
2004

Spatial and temporal control of nuclear envelope assembly by Ran GTPase.

Clarke, P. R. & Zhang, C., 1 Jan 2004, In : Symposia of the Society for Experimental Biology. 56, p. 193-204 12 p.

Research output: Contribution to journalReview article

18 Citations (Scopus)
2002

Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly

Zhang, C., Golderg, M. W., Moore, W. J., Allen, T. D. & Clarke, P. R., 1 Nov 2002, In : European Journal of Cell Biology. 81, 11, p. 623-633 11 p.

Research output: Contribution to journalReview article

37 Citations (Scopus)
66 Citations (Scopus)
2001

Ran GTPase: A master regulator of nuclear structure and function during the eukaryotic cell division cycle?

Clarke, P. R. & Zhang, C., 1 Sep 2001, In : Trends in Cell Biology. 11, 9, p. 366-371 6 p.

Research output: Contribution to journalReview article

106 Citations (Scopus)

Therapeutic potential of ischaemic preconditioning

Edwards, R. J., Saurin, A. T., Rakhit, R. D. & Marber, M. S., 24 Dec 2001, In : British Journal of Clinical Pharmacology. 50, 2, p. 87-97 11 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)
2000
211 Citations (Scopus)