Cellular Medicine

Research Output 1984 2020

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Review article
2019
19 Citations (Scopus)
50 Downloads (Pure)

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

Cuadrado, A., Rojo, A. I., Wells, G., Hayes, J., Cousin, S. P., Rumsey, W. L., Attucks, O. C., Franklin, S., Levonen, A-L., Kensler, T. W. & Dinkova-Kostova, A., Apr 2019, In : Nature Reviews Drug Discovery. 18, 4, p. 295-317 23 p.

Research output: Contribution to journalReview article

Open Access
File
Chronic Disease
NF-E2-Related Factor 2
Ubiquitin-Protein Ligases
Cytoprotection
Neurodegenerative Diseases

What is the potential of p53 isoforms as a predictive biomarker in the treatment of cancer?

Hayman, L., Chaudhry, W. R., Revin, V. V., Zhelev, N. & Bourdon, J-C., Feb 2019, In : Expert Review of Molecular Diagnostics. 19, 2, p. 149-159 11 p.

Research output: Contribution to journalReview article

Protein Isoforms
Biomarkers
Neoplasms
Oncogenes
Regeneration
2018
10 Citations (Scopus)
55 Downloads (Pure)

Kinase and Phosphatase Cross-Talk at the Kinetochore

Saurin, A. T., 19 Jun 2018, In : Frontiers in Cell and Developmental Biology. 6, p. 1-23 23 p., 62.

Research output: Contribution to journalReview article

Open Access
File
Kinetochores
Phosphoric Monoester Hydrolases
Phosphotransferases
Enzymes
M Phase Cell Cycle Checkpoints
4 Citations (Scopus)
79 Downloads (Pure)

Phenethyl isothiocyanate, a dual activator of transcription factors NRF2 and HSF1

Dayalan Naidu, S., Suzuki, T., Yamamoto, M., Fahey, J. W. & Dinkova-Kostova, A., 1 Sep 2018, In : Molecular Nutrition & Food Research. 62, 18, p. e1700908 9 p., 1700908.

Research output: Contribution to journalReview article

Open Access
File
isothiocyanates
heat stress
transcription factors
Vegetables
Glucosinolates
22 Citations (Scopus)
126 Downloads (Pure)

The role of Nrf2 signaling in counteracting neurodegenerative diseases

Dinkova-Kostova, A. T., Kostov, R. V. & Kazantsev, A. G., 1 Oct 2018, In : FEBS Journal. 285, 19, p. 3576-3590 15 p.

Research output: Contribution to journalReview article

Open Access
File
Neurodegenerative diseases
Neurodegenerative Diseases
Antioxidants
Detoxification
NF-E2 Transcription Factor
2005
16 Citations (Scopus)

A gradient signal orchestrates the mitotic spindle

Clarke, P. R., 26 Aug 2005, In : Science. 309, 5739, p. 1334-1335 2 p.

Research output: Contribution to journalReview article

269 Citations (Scopus)

The role of Keap1 in cellular protective responses

Dinkova-Kostova, A. T., Holtzclaw, W. D. & Kensler, T. W., 1 Dec 2005, In : Chemical Research in Toxicology. 18, 12, p. 1779-1791 13 p.

Research output: Contribution to journalReview article

2004
18 Citations (Scopus)

Spatial and temporal control of nuclear envelope assembly by Ran GTPase.

Clarke, P. R. & Zhang, C., 1 Jan 2004, In : Symposia of the Society for Experimental Biology. 56, p. 193-204 12 p.

Research output: Contribution to journalReview article

GTP Phosphohydrolases
Nuclear Envelope
Guanosine Triphosphate
beta Karyopherins
Chromatin
2002
37 Citations (Scopus)

Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly

Zhang, C., Golderg, M. W., Moore, W. J., Allen, T. D. & Clarke, P. R., 1 Nov 2002, In : European Journal of Cell Biology. 81, 11, p. 623-633 11 p.

Research output: Contribution to journalReview article

Nuclear Pore
Nuclear Envelope
Chromatin
Guanosine Triphosphate
Membranes
65 Citations (Scopus)
Edible Plants
Enzymes
Neoplasms
Carcinogenesis
Animal Models
2001
105 Citations (Scopus)

Ran GTPase: A master regulator of nuclear structure and function during the eukaryotic cell division cycle?

Clarke, P. R. & Zhang, C., 1 Sep 2001, In : Trends in Cell Biology. 11, 9, p. 366-371 6 p.

Research output: Contribution to journalReview article

Cell Nucleus Active Transport
GTP Phosphohydrolases
Eukaryotic Cells
Cell Cycle
Karyopherins
24 Citations (Scopus)

Therapeutic potential of ischaemic preconditioning

Edwards, R. J., Saurin, A. T., Rakhit, R. D. & Marber, M. S., 24 Dec 2001, In : British Journal of Clinical Pharmacology. 50, 2, p. 87-97 11 p.

Research output: Contribution to journalReview article

2000
205 Citations (Scopus)
NAD(P)H Dehydrogenase (Quinone)
Quinones
Toxicity
Hydroquinones
Dicumarol