Cellular Medicine

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• An Evaluation of Transforming Growth Factor-β Signalling in Adult Glioblastoma

  Author: Willison, A., 2019

  Supervisor: Inman, G. (Supervisor) & Hossain-Ibrahim, K. (Supervisor)

  Student thesis: Master's Thesis › Master of Science

• Characterisation of novel mechanisms of resistance to single-agent and combination chemotherapy in ovarian cancer

  Author: Vaidyanathan, A., 2019

  Supervisor: Smith, G. (Supervisor), Clarke, P. (Supervisor) & Herrington, S. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Dual regulation of transcription factor Nrf2 by Keap1 and the beta-TrCP/GSK-3 in cancer

  Author: Ebisine, K., 2019

  Supervisor: Hayes, J. (Supervisor) & Dinkova-Kostova, A. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Generation of Stem Cell Based Models to Investigate Pancreatic Neuroendocrine Tumorigenesis

  Author: Poland, C. C., 2021

  Supervisor: Newey, P. (Supervisor) & Sutherland, C. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Influence of genotoxic drug-induced post-translational modifications on mutant p53 stability and oncogenic activities

  Author: Estevan Barber, A., 2018

  Supervisor: Bourdon, J. (Supervisor), Fuller-Pace, F. (Supervisor) & Meek, D. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Inhibition of PLK1 by p53 and by PLK1-targeted drugs

  Author: Ahmadi, M., 2018

  Supervisor: Meek, D. (Supervisor), Clarke, P. R. (Supervisor) & Fuller-Pace, F. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating DNA Methylation Changes in a Preclinical Murine Model of Cutaneous Squamous Cell Carcinoma

  Author: Roth, K., 2019

  Supervisor: Dinkova-Kostova, A. (Supervisor) & Hayes, J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating nutrient excess and endothelial dysfunction: a role for BACE1 and amyloid?

  Author: Coull, B. M., 2020

  Supervisor: Ashford, M. (Supervisor) & Sutherland, C. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating the Interplay between Kinases and Phosphatases at the Kinetochore

  Author: Smith, R., 2021

  Supervisor: Saurin, A. (Supervisor) & Hiom, K. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Investigating the role of the Nrf2-Keap1 pathway in mitophagy

  Author: Bento-Pereira, C., 2020

  Supervisor: Dinkova-Kostova, A. (Supervisor) & Muqit, M. (Supervisor)

  Student thesis: Master's Thesis › Master of Science

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• Investigating the role of transcription factor Nrf2 in the pathogenesis of NAFLD

  Author: Wood, K. L., 2017

  Supervisor: Dillon, J. (Supervisor) & Hayes, J. (Supervisor)

  Student thesis: Master's Thesis › Master of Science

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• Mechanisms of repression of the transcription factor NRF2 by KEAP1- and B-TrCP-dependent ubiquitin ligases and how the dysregulation of NRF2 contributes to lung cancer progression

  Author: Robertson, H., 2019

  Supervisor: Hayes, J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Molecular and Genetic Mechanisms in Atopic Eczema

  Author: Brown, S. J., 2020

  Supervisor: Fuller-Pace, F. (Supervisor) & Hayes, J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• PP2A-B56 isoform specificity at the centromere and kinetochore

  Author: Vallardi, G., 2018

  Supervisor: Saurin, A. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The Non-Wnt Functions of APC: Unravelling the Link between APC and Apoptosis

  Author: Cuddihy, J., 2016

  Supervisor: Hiom, K. (Supervisor) & Nathke, I. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Medicine

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• The Role of Amino Acid Transport in the Regulation of mTORC1 by Metformin

  Author: Forteath, C. D., 2017

  Supervisor: Rena, N. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Towards development of new strategies for inhibiting skin cancer progression

  Author: Nobre Salvador, D., 2019

  Supervisor: Dinkova-Kostova, A. (Supervisor), Proby, C. (Supervisor), Sherwood, V. (Supervisor) & Morris, C. (External person) (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy