Centre for Advanced Scientific Technologies

  • United Kingdom

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Proteomics Medicine & Life Sciences
Phosphorylation Chemical Compounds
Imaging techniques Chemical Compounds
GMP synthase (glutamine-hydrolyzing) Medicine & Life Sciences
Chemical activation Chemical Compounds
Mitochondrial Degradation Medicine & Life Sciences
Proteins Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences

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No photo of Paul Appleton

Appleton, Paul

No photo of Rosemary Clarke

Clarke, Rosemary

No photo of Yongchang Fan

Fan, Yongchang


Research Output 2015 2018

  • 258 Citations
  • 8 h-Index
  • 21 Article
  • 2 Conference contribution
  • 1 Chapter
30 Citations

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

McWilliams, T. G., Prescott, A. R., Montava-Garriga, L., Ball, G., Singh, F., Barini, E., Muqit, M. M. K., Brooks, S. P. & Ganley, I. G., 6 Feb 2018, In : Cell Metabolism. 27, 2, p. 439-449.e5 17 p., e5.

Research output: Contribution to journalArticle

Open Access
Mitochondrial Degradation
Parkinson Disease
Dopaminergic Neurons
Islets of Langerhans

Phosphorylation of Parkin at Serine65 is essential for its activation in vivo

McWilliams, T. G., Barini, E., Pohjolan-Pirhonen, R., Brooks, S. P., Singh, F., Burel, S., Balk, K., Kumar, A., Montava Garriga, L., Prescott, A., Hassoun, S. M., Mouton-Liger, F., Ball, G., Hills, R., Knebel, A., Ulusoy, A., Di Monte, D. A., Tamjar, J., Antico, O., Fears, K. & 11 othersSmith, L., Brambilla, R., Palin, E., Valori, M., Eerola-Rautio, J., Tienari, P., Corti, O., Dunnett, S. B., Ganley, I., Suomalainen, A. & Muqit, M., 7 Nov 2018, In : Open Biology. 8, 11, 18 p., 181108.

Research output: Contribution to journalArticle

Open Access
Chemical activation

UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy

Shorrock, H. K., van der Hoorn, D., Boyd, P. J., Llavero Hurtado, M., Lamont, D. J., Wirth, B., Sleigh, J. N., Schiavo, G., Wishart, T. M., Groen, E. J. N. & Gillingwater, T. H., 1 Oct 2018, In : Brain. 141, 10, p. 2878-2894 17 p.

Research output: Contribution to journalArticle

Open Access
Spinal Muscular Atrophy
Sensory Receptor Cells
Charcot-Marie-Tooth Disease
Amino Acyl-tRNA Synthetases