Centre for Targeted Protein Degradation

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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  • 14-3-3 Protein-Protein Interactions: From Mechanistic Understanding to Their Small-Molecule Stabilization

    Somsen, B. A., Cossar, P. J., Arkin, M. R., Brunsveld, L. & Ottmann, C. (Lead / Corresponding author), 15 Jul 2024, In: ChemBioChem. 25, 14, 14 p., e202400214.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    File
    1 Citation (Scopus)
    15 Downloads (Pure)

  • Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules

    Dodd, D. O., Mechaussier, S., Yeyati, P. L., McPhie, F., Anderson, J. R., Khoo, C. J., Shoemark, A., Gupta, D. K., Attard, T., Zariwala, M. A., Legendre, M., Bracht, D., Wallmeier, J., Gui, M., Fassad, M. R., Parry, D. A., Tennant, P. A., Meynert, A., Wheway, G. & Fares-Taie, L. & 65 others, Black, H. A., Mitri-Frangieh, R., Faucon, C., Kaplan, J., Patel, M., McKie, L., Megaw, R., Gatsogiannis, C., Mohamed, M. A., Aitken, S., Gautier, P., Reinholt, F. R., Hirst, R. A., O’Callaghan, C., Heimdal, K., Bottier, M., Escudier, E., Crowley, S., Descartes, M., Jabs, E. W., Kenia, P., Amiel, J., Bacci, G. M., Calogero, C., Palazzo, V., Tiberi, L., Blümlein, U., Rogers, A., Wambach, J. A., Wegner, D. J., Fulton, A. B., Kenna, M., Rosenfeld, M., Holm, I. A., Quigley, A., Hall, E. A., Murphy, L. C., Cassidy, D. M., von Kriegsheim, A., Scottish Genomes Partnership, Genomics England Research Consortium, Undiagnosed Diseases Network, Papon, J.-F., Pasquier, L., Murris, M. S., Chalmers, J. D., Hogg, C., Macleod, K. A., Macleod, K. A., Urquhart, D. S., Unger, S., Aitman, T. J., Amselem, S., Leigh, M. W., Knowles, M. R., Omran, H., Mitchison, H. M., Brown, A., Marsh, J. A., Welburn, J. P. I., Ti, S.-C., Horani, A., Rozet, J.-M., Perrault, I. (Lead / Corresponding author) & Mill, P. (Lead / Corresponding author), 26 Apr 2024, In: Science. 384, 6694, eadf5489.

    Research output: Contribution to journal › Article › peer-review

    9 Citations (Scopus)

  • Combination of AID2 and BromoTag expands the utility of degron-based protein knockdowns

    Hatoyama, Y., Islam, M., Bond, A. G., Hayashi, K. I., Ciulli, A. & Kanemaki, M. T. (Lead / Corresponding author), 10 Sept 2024, In: EMBO Reports. 25, 9, p. 4062-4077 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    16 Downloads (Pure)
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